Lista de obras -

A model for the origin of TCR-alphabeta+ CD4-CD8- B220+ cells based on high affinity TCR signals

artículo científico publicado en 1999

Abnormal regulation of the IL-2 promoter in lpr CD4-CD8- T lymphocytes results in constitutive expression of a novel nuclear factor of activated T cells-binding factor

artículo científico publicado en 1995

Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4+ T cells

artículo científico publicado en 2007

Activation of gamma delta T cells by Borrelia burgdorferi is indirect via a TLR- and caspase-dependent pathway

artículo científico publicado en 2008

Anti-CD40L accelerates renal disease and adenopathy in MRL-lpr mice in parallel with decreased thymocyte apoptosis ⬇️

artículo científico publicado el 15 de julio de 1998

Apoptosis of Fashigh CD4+ synovial T cells by borrelia-reactive Fas-ligand(high) gamma delta T cells in Lyme arthritis

artículo científico publicado en 1996

Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity

artículo científico publicado en 2008

Apoptosis regulators Fas and Bim synergistically control T-lymphocyte homeostatic proliferation

artículo científico publicado en 2010

Attenuation of apoptosis and the eye of the beholder

artículo científico publicado en 2008

Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π.

artículo científico publicado en 2016

Augmentation of proliferation of vascular smooth muscle cells by plasminogen activator inhibitor type 1.

artículo científico publicado en 2006

Biased T-Cell Antigen Receptor Repertoire in Lyme Arthritis ⬇️

artículo científico publicado el 1 de marzo de 1998

CD2-CD4-CD8- lymph node T lymphocytes in MRL lpr/lpr mice are derived from a CD2+CD4+CD8+ thymic precursor ⬇️

artículo científico publicado el 15 de julio de 1993

Caspase activation is required for T cell proliferation

artículo científico publicado en 1999

Caspase-8 and FLIP Regulate RIG-I/MDA5-induced Innate Immune Host Responses to Picornaviruses ⬇️

artículo científico publicado el 1 de diciembre de 2012

Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.

artículo científico publicado en 2007

Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation

artículo científico publicado en 2005

Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8.

artículo científico publicado en 2005

Cellular FLIP long form-transgenic mice manifest a Th2 cytokine bias and enhanced allergic airway inflammation

artículo científico publicado en 2004

Co-stimulation via CD28 induces activation of a refractory subset of MRL-Ipr/Ipr T lymphocytes

artículo científico publicado en 1993

Comment on “Essential Role of IL-17A in the Formation of a Mycobacterial Infection-Induced Granuloma in the Lung” ⬇️

artículo científico publicado el 15 de agosto de 2010

Decreased CD4-CD8- TCR-alpha beta + cells in lpr/lpr mice lacking beta 2-microglobulin

scientific article published on 01 March 1995

Delayed kinetics of T lymphocyte anergy and deletion in lpr mice

artículo científico publicado en 1994

Detection of Cell Surface Ligands for Human Synovial γδ T Cells

scientific article published on 23 September 2019

Diversity of rheumatoid synovial tissue T cells by T cell receptor analysis. Oligoclonal expansion in interleukin-2-responsive cells

scientific article published on 01 May 1991

Down-modulation of CD2 delays deletion of superantigen-responsive T cells ⬇️

artículo científico publicado el 1 de enero de 1998

Effector CD4+ T cells generate intermediate caspase activity and cleavage of caspase-8 substrates

artículo científico publicado en 2005

Expression level of c-FLIP versus Fas determines susceptibility to Fas ligand-induced cell death in murine thymoma EL-4 cells

artículo científico publicado en 2002

Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contacts ⬇️

artículo científico publicado el 25 de enero de 2011

Fas ligand deficiency impairs host inflammatory response against infection with the spirochete Borrelia burgdorferi

artículo científico publicado en 2006

Gammadelta T cells promote a Th1 response during coxsackievirus B3 infection in vivo: role of Fas and Fas ligand

artículo científico publicado en 2002

Glycolysis Induces MCJ Expression That Links T Cell Proliferation With Caspase-3 Activity and Death

Glycolysis promotes caspase-3 activation in lipid rafts in T cells

artículo científico publicado en 2018

High expression of Fas ligand by synovial fluid-derived gamma delta T cells in Lyme arthritis

artículo científico publicado en 2003

IL-15 maintains T-cell survival via S-nitrosylation-mediated inhibition of caspase-3

artículo científico publicado en 2014

In vivo levels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice.

artículo científico publicado en 2014

Increased caspase activity primes human Lyme arthritis synovial γδ T cells for proliferation and death ⬇️

artículo científico publicado el 22 de septiembre de 2011

Inhibition of apoptosis and caspase-3 in vascular smooth muscle cells by plasminogen activator inhibitor type-1.

artículo científico publicado en 2004

Interleukin-1 receptor and caspase-1 are required for the Th17 response in nitrogen dioxide-promoted allergic airway disease

artículo científico publicado en 2013

Introduction: lessons from the lpr mouse--T lymphocyte development

scientific article published on 01 February 1994

JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells

artículo científico publicado en 1996

Liver Damage Preferentially Results from CD8+ T Cells Triggered by High Affinity Peptide Antigens ⬇️

artículo científico publicado el 21 de septiembre de 1998

Liver Damage by Infiltrating CD8+ T Cells Is Fas Dependent ⬇️

artículo científico publicado el 1 de diciembre de 2001

Lyme arthritis synovial gamma delta T cells respond to Borrelia burgdorferi lipoproteins and lipidated hexapeptides

Lyme arthritis synovial gammadelta T cells instruct dendritic cells via fas ligand

scientific article published on 01 November 2005

Morphological and cytochemical determination of cell death by apoptosis

artículo científico publicado en 2007

Necroptosis of Dendritic Cells Promotes Activation of γδ T Cells.

artículo científico publicado en 2016

Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis

artículo científico publicado en 2012

Parallels in T lymphocyte development between lpr and normal mice

artículo científico publicado en 1994

Phosphorylation of FADD/MORT1 and Fas by kinases that associate with the membrane-proximal cytoplasmic domain of Fas ⬇️

artículo científico publicado el 15 de mayo de 1998

Proliferating γδ T cells manifest high and spatially confined caspase‐3 activity ⬇️

artículo científico publicado el 1 de abril de 2012

Prominent T lymphocyte response to Borrelia burgdorferi from peripheral blood of unexposed donors

artículo científico publicado en 1994

Proteolytic regulation of nuclear factor of activated T (NFAT) c2 cells and NFAT activity by caspase-3.

artículo científico publicado en 2006

Reactive nitrogen species-induced cell death requires Fas-dependent activation of c-Jun N-terminal kinase

artículo científico publicado en 2004

Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus

artículo científico publicado en 2016

Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas.

artículo científico publicado en 2009

Redox-based regulation of apoptosis: S-glutathionylation as a regulatory mechanism to control cell death

artículo científico publicado en 2012

Reduced immune response to Borrelia burgdorferi in the absence of γδ T cells.

artículo científico publicado en 2011

Reduced myocarditis following Coxsackievirus infection in cellular FLICE inhibitory protein--long form-transgenic mice

artículo científico publicado en 2006

Reducing protein oxidation reverses lung fibrosis

scientific article published on 09 July 2018

Regulation of apoptosis through cysteine oxidation: implications for fibrotic lung disease.

artículo científico publicado en 2010

Reversal of hyporesponsiveness in lpr CD4-CD8- T cells is achieved by induction of cell cycling and normalization of CD2 and p59fyn expression

artículo científico publicado en 1994

Selective DNA Demethylation Accompanies T Cell Homeostatic Proliferation and Gene Regulation in Lupus-Prone lpr Mice

artículo científico publicado en 2020

Serum amyloid A inhibits dendritic cell apoptosis to induce glucocorticoid resistance in CD4(+) T cells

artículo científico publicado en 2013

Spatial differences in active caspase-8 defines its role in T-cell activation versus cell death

artículo científico publicado en 2008

Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice

scientific article published on 16 April 2020

The c-FLIPL cleavage product p43FLIP promotes activation of extracellular signal-regulated kinase (ERK), nuclear factor κB (NF-κB), and caspase-8 and T cell survival

artículo científico publicado en 2013

The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes

artículo científico publicado en 2002

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

artículo científico publicado en 2000

The death receptor Fas (CD95/APO-1) mediates the deletion of T lymphocytes undergoing homeostatic proliferation

artículo científico publicado en 2005

The molecular signature of murine T cell homeostatic proliferation reveals both inflammatory and immune inhibition patterns

artículo científico publicado en 2017

The origin of CD4-CD8-TCR alpha beta+ thymocytes: a model based on T-cell receptor avidity

artículo científico publicado en 1995

The role of sex differences in autophagy in the heart during coxsackievirus B3-induced myocarditis

artículo científico publicado en 2014

Transgene-encoded human CD2 acts in a dominant negative fashion to modify thymocyte selection signals in mice

artículo científico publicado en 1996

Unstimulated Rheumatoid Synovial T‐Cells Have a Consistent Vβ Gene Bias when Compared to Peripheral Blood T‐Cells ⬇️

artículo científico publicado el 7 de julio de 1995

c-FLIP(S) reduces activation of caspase and NF-kappaB pathways and decreases T cell survival

artículo científico publicado en 2008

c-FLIP-Short reduces type I interferon production and increases viremia with coxsackievirus B3

artículo científico publicado en 2014

cFLIP regulation of lymphocyte activation and development

artículo científico publicado en 2006

Lista de obras de

A model for the origin of TCR-alphabeta+ CD4-CD8- B220+ cells based on high affinity TCR signals

Abnormal regulation of the IL-2 promoter in lpr CD4-CD8- T lymphocytes results in constitutive expression of a novel nuclear factor of activated T cells-binding factor

Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4+ T cells

Activation of gamma delta T cells by Borrelia burgdorferi is indirect via a TLR- and caspase-dependent pathway

Anti-CD40L accelerates renal disease and adenopathy in MRL-lpr mice in parallel with decreased thymocyte apoptosis ⬇️

Apoptosis of Fashigh CD4+ synovial T cells by borrelia-reactive Fas-ligand(high) gamma delta T cells in Lyme arthritis

Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity

Apoptosis regulators Fas and Bim synergistically control T-lymphocyte homeostatic proliferation

Attenuation of apoptosis and the eye of the beholder

Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π.

Augmentation of proliferation of vascular smooth muscle cells by plasminogen activator inhibitor type 1.

Biased T-Cell Antigen Receptor Repertoire in Lyme Arthritis ⬇️

CD2-CD4-CD8- lymph node T lymphocytes in MRL lpr/lpr mice are derived from a CD2+CD4+CD8+ thymic precursor ⬇️

Caspase activation is required for T cell proliferation

Caspase-8 and FLIP Regulate RIG-I/MDA5-induced Innate Immune Host Responses to Picornaviruses ⬇️

Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.

Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation

Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8.

Cellular FLIP long form-transgenic mice manifest a Th2 cytokine bias and enhanced allergic airway inflammation

Co-stimulation via CD28 induces activation of a refractory subset of MRL-Ipr/Ipr T lymphocytes

Comment on “Essential Role of IL-17A in the Formation of a Mycobacterial Infection-Induced Granuloma in the Lung” ⬇️

Decreased CD4-CD8- TCR-alpha beta + cells in lpr/lpr mice lacking beta 2-microglobulin

Delayed kinetics of T lymphocyte anergy and deletion in lpr mice

Detection of Cell Surface Ligands for Human Synovial γδ T Cells

Diversity of rheumatoid synovial tissue T cells by T cell receptor analysis. Oligoclonal expansion in interleukin-2-responsive cells

Down-modulation of CD2 delays deletion of superantigen-responsive T cells ⬇️

Effector CD4+ T cells generate intermediate caspase activity and cleavage of caspase-8 substrates

Expression level of c-FLIP versus Fas determines susceptibility to Fas ligand-induced cell death in murine thymoma EL-4 cells

Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contacts ⬇️

Fas ligand deficiency impairs host inflammatory response against infection with the spirochete Borrelia burgdorferi

Gammadelta T cells promote a Th1 response during coxsackievirus B3 infection in vivo: role of Fas and Fas ligand

Glycolysis Induces MCJ Expression That Links T Cell Proliferation With Caspase-3 Activity and Death

Glycolysis promotes caspase-3 activation in lipid rafts in T cells

High expression of Fas ligand by synovial fluid-derived gamma delta T cells in Lyme arthritis

IL-15 maintains T-cell survival via S-nitrosylation-mediated inhibition of caspase-3

In vivo levels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice.

Increased caspase activity primes human Lyme arthritis synovial γδ T cells for proliferation and death ⬇️

Inhibition of apoptosis and caspase-3 in vascular smooth muscle cells by plasminogen activator inhibitor type-1.

Interleukin-1 receptor and caspase-1 are required for the Th17 response in nitrogen dioxide-promoted allergic airway disease

Introduction: lessons from the lpr mouse--T lymphocyte development

JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells

Liver Damage Preferentially Results from CD8+ T Cells Triggered by High Affinity Peptide Antigens ⬇️

Liver Damage by Infiltrating CD8+ T Cells Is Fas Dependent ⬇️

Lyme arthritis synovial gamma delta T cells respond to Borrelia burgdorferi lipoproteins and lipidated hexapeptides

Lyme arthritis synovial gammadelta T cells instruct dendritic cells via fas ligand

Morphological and cytochemical determination of cell death by apoptosis

Necroptosis of Dendritic Cells Promotes Activation of γδ T Cells.

Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis

Parallels in T lymphocyte development between lpr and normal mice

Phosphorylation of FADD/MORT1 and Fas by kinases that associate with the membrane-proximal cytoplasmic domain of Fas ⬇️

Proliferating γδ T cells manifest high and spatially confined caspase‐3 activity ⬇️

Prominent T lymphocyte response to Borrelia burgdorferi from peripheral blood of unexposed donors

Proteolytic regulation of nuclear factor of activated T (NFAT) c2 cells and NFAT activity by caspase-3.

Reactive nitrogen species-induced cell death requires Fas-dependent activation of c-Jun N-terminal kinase

Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus

Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas.

Redox-based regulation of apoptosis: S-glutathionylation as a regulatory mechanism to control cell death

Reduced immune response to Borrelia burgdorferi in the absence of γδ T cells.

Reduced myocarditis following Coxsackievirus infection in cellular FLICE inhibitory protein--long form-transgenic mice

Reducing protein oxidation reverses lung fibrosis

Regulation of apoptosis through cysteine oxidation: implications for fibrotic lung disease.

Reversal of hyporesponsiveness in lpr CD4-CD8- T cells is achieved by induction of cell cycling and normalization of CD2 and p59fyn expression

Selective DNA Demethylation Accompanies T Cell Homeostatic Proliferation and Gene Regulation in Lupus-Prone lpr Mice

Serum amyloid A inhibits dendritic cell apoptosis to induce glucocorticoid resistance in CD4(+) T cells

Spatial differences in active caspase-8 defines its role in T-cell activation versus cell death

Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice

The c-FLIPL cleavage product p43FLIP promotes activation of extracellular signal-regulated kinase (ERK), nuclear factor κB (NF-κB), and caspase-8 and T cell survival

The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

The death receptor Fas (CD95/APO-1) mediates the deletion of T lymphocytes undergoing homeostatic proliferation

The molecular signature of murine T cell homeostatic proliferation reveals both inflammatory and immune inhibition patterns

The origin of CD4-CD8-TCR alpha beta+ thymocytes: a model based on T-cell receptor avidity

The role of sex differences in autophagy in the heart during coxsackievirus B3-induced myocarditis

Transgene-encoded human CD2 acts in a dominant negative fashion to modify thymocyte selection signals in mice

Unstimulated Rheumatoid Synovial T‐Cells Have a Consistent Vβ Gene Bias when Compared to Peripheral Blood T‐Cells ⬇️

c-FLIP(S) reduces activation of caspase and NF-kappaB pathways and decreases T cell survival

c-FLIP-Short reduces type I interferon production and increases viremia with coxsackievirus B3

cFLIP regulation of lymphocyte activation and development