Lista de obras - Michael M. C. Lai - Dominio Público Uruguay

A Nucleolar Protein, Ribosomal RNA Processing 1 Homolog B (RRP1B), Enhances the Recruitment of Cellular mRNA in Influenza Virus Transcription

artículo científico publicado en 2015

A host susceptibility gene, DR1, facilitates influenza A virus replication by suppressing host innate immunity and enhancing viral RNA replication

artículo científico publicado en 2015

Activation of anti-hepatitis C virus responses via Toll-like receptor 7.

artículo científico publicado en 2006

Annexin A2 is involved in the formation of hepatitis C virus replication complex on the lipid raft

artículo científico publicado en 2012

Association of hepatitis C virus replication complexes with microtubules and actin filaments is dependent on the interaction of NS3 and NS5A

artículo científico publicado en 2008

Attenuation of 40S Ribosomal Subunit Abundance Differentially Affects Host and HCV Translation and Suppresses HCV Replication ⬇️

artículo científico publicado el 28 de junio de 2012

CNOT4-Mediated Ubiquitination of Influenza A Virus Nucleoprotein Promotes Viral RNA Replication

artículo científico publicado en 2017

Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts

artículo científico publicado en 2004

Critical Role of Virion-Associated Cholesterol and Sphingolipid in Hepatitis C Virus Infection

artículo científico publicado en 2008

Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins

scientific article (publication date: December 2015)

Detection and characterization of small and large HDV antigens

artículo científico publicado en 2004

Detection of a Novel Unglycosylated Form of Hepatitis C Virus E2 Envelope Protein That Is Located in the Cytosol and Interacts with PKR ⬇️

artículo científico publicado el 1 de febrero de 2002

Enzymatic characterization of the full-length and C-terminally truncated hepatitis C virus RNA polymerases: function of the last 21 amino acids of the C terminus in template binding and RNA synthesis

artículo científico publicado en 2004

Establishment of B-cell lymphoma cell lines persistently infected with hepatitis C virus in vivo and in vitro: the apoptotic effects of virus infection

artículo científico publicado en 2003

Genomic but not antigenomic hepatitis delta virus RNA is preferentially exported from the nucleus immediately after synthesis and processing

artículo científico publicado en 2002

HCV core expression in hepatocytes protects against autoimmune liver injury and promotes liver regeneration in mice

artículo científico publicado en 2006

HCV infection enhances Th17 commitment, which could affect the pathogenesis of autoimmune diseases

artículo científico publicado en 2014

HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication

artículo científico publicado en 2017

Hepatitis C Virus (HCV)-Induced Immunoglobulin Hypermutation Reduces the Affinity and Neutralizing Activities of Antibodies against HCV Envelope Protein

artículo científico publicado en 2008

Hepatitis C Virus Causes Uncoupling of Mitotic Checkpoint and Chromosomal Polyploidy through the Rb Pathway

artículo científico publicado en 2009

Hepatitis C Virus Genotype 1b Core Protein Does Not Exert Immunomodulatory Effects on Virus-Induced Cellular Immunity ⬇️

artículo científico publicado el 1 de febrero de 2002

Hepatitis C Virus Inhibits DNA Damage Repair through Reactive Oxygen and Nitrogen Species and by Interfering with the ATM-NBS1/Mre11/Rad50 DNA Repair Pathway in Monocytes and Hepatocytes ⬇️

artículo científico publicado el 25 de octubre de 2010

Hepatitis C Virus RNA Replication Occurs on a Detergent-Resistant Membrane That Cofractionates with Caveolin-2

artículo científico publicado en 2003

Hepatitis C Virus Triggers Mitochondrial Permeability Transition with Production of Reactive Oxygen Species, Leading to DNA Damage and STAT3 Activation

artículo científico publicado en 2006

Hepatitis C virus E2-CD81 interaction induces hypermutation of the immunoglobulin gene in B cells

artículo científico publicado en 2005

Hepatitis C virus IRES-dependent translation is insensitive to an eIF2alpha-independent mechanism of inhibition by interferon in hepatocyte cell lines

artículo científico publicado en 2002

Hepatitis C virus NS3/4A protein interacts with ATM, impairs DNA repair and enhances sensitivity to ionizing radiation.

artículo científico publicado en 2007

Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins

artículo científico publicado en 2002

Hepatitis C virus core protein regulates p300/CBP co-activation function. Possible role in the regulation of NF-AT1 transcriptional activity

artículo científico publicado en 2004

Hepatitis C virus egress and release depend on endosomal trafficking of core protein

artículo científico publicado en 2010

Hepatitis C virus has a genetically determined lymphotropism through co-receptor B7.2.

artículo científico publicado en 2017

Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes

scholarly article

Hepatitis C virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon and interleukin-6

artículo científico publicado en 2006

Hepatitis C virus infection activates the immunologic (type II) isoform of nitric oxide synthase and thereby enhances DNA damage and mutations of cellular genes

artículo científico publicado en 2004

Hepatitis C virus infection of T cells inhibits proliferation and enhances fas-mediated apoptosis by down-regulating the expression of CD44 splicing variant 6.

artículo científico publicado en 2009

Hepatitis C virus infects T cells and affects interferon-gamma signaling in T cell lines

artículo científico publicado en 2006

Hepatitis C virus nonstructural 5B protein regulates tumor necrosis factor alpha signaling through effects on cellular IkappaB kinase

artículo científico publicado en 2006

Hepatitis C virus proteins: direct link to hepatic oxidative stress, steatosis, carcinogenesis and more

artículo científico publicado en 2002

Hepatitis C virus translation preferentially depends on active RNA replication

artículo científico publicado en 2012

Hepatitis Delta Virus RNA Encoding the Large Delta Antigen Cannot Sustain Replication due to Rapid Accumulation of Mutations Associated with RNA Editing ⬇️

artículo científico publicado el 1 de noviembre de 2003

Hepatitis Delta Virus RNA Replication ⬇️

artículo científico publicado el 6 de noviembre de 2009

Hepatitis delta virus RNA transfection for the cell culture model

artículo científico publicado en 2004

Hepatitis delta virus antigen is methylated at arginine residues, and methylation regulates subcellular localization and RNA replication

artículo científico publicado en 2004

High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity

artículo científico publicado en 2010

Household transmission of respiratory viruses - assessment of viral, individual and household characteristics in a population study of healthy Australian adults.

artículo científico publicado en 2012

How Dengue Virus Circumvents Innate Immunity

Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B

artículo científico publicado en 2005

Human monoclonal antibody to hepatitis C virus E1 glycoprotein that blocks virus attachment and viral infectivity

artículo científico publicado en 2004

Identification of RNA ligands that bind hepatitis C virus polymerase selectively and inhibit its RNA synthesis from the natural viral RNA templates

artículo científico publicado en 2003

Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy ⬇️

artículo científico publicado el 1 de octubre de 2003

Immunogenicity of a monovalent 2009 influenza A(H1N1) vaccine in infants and children: a randomized trial.

artículo científico publicado en 2009

Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase

artículo científico publicado en 2003

Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft

artículo científico publicado en 2004

Involvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A protein

artículo científico publicado en 2009

Is avian influenza A (H7N9) virus staggering its way to humans?

artículo científico publicado en 2013

Large hepatitis delta antigen is not a suppressor of hepatitis delta virus RNA synthesis once RNA replication is established ⬇️

artículo científico publicado en 2002

Modification of small hepatitis delta virus antigen by SUMO protein

artículo científico publicado en 2009

Molecular pathogenesis of Gilbert's syndrome: decreased TATA-binding protein binding affinity of UGT1A1 gene promoter

artículo científico

Multiple type A/B heterogeneous nuclear ribonucleoproteins (hnRNPs) can replace hnRNP A1 in mouse hepatitis virus RNA synthesis

artículo científico publicado en 2003

Murine Retroviral Pseudotype Virus Containing Hepatitis B Virus Large and Small Surface Antigens Confers Specific Tropism for Primary Human Hepatocytes: a Potential Liver-Specific Targeting System ⬇️

artículo científico publicado el 1 de enero de 2002

Murine coronavirus requires lipid rafts for virus entry and cell-cell fusion but not for virus release

artículo científico publicado en 2005

Mutagenic and inhibitory effects of ribavirin on hepatitis C virus RNA polymerase

artículo científico publicado en 2003

Nonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activation

artículo científico publicado en 2002

Nonstructural protein 5A is incorporated into hepatitis C virus low-density particle through interaction with core protein and microtubules during intracellular transport

artículo científico publicado en 2014

Palmitoylation and Polymerization of Hepatitis C Virus NS4B Protein

artículo científico publicado en 2006

Polo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5A

artículo científico publicado en 2010

Polo-like-kinase 1: A key cellular target for anti-HBV therapy?

artículo científico publicado en 2017

Poly(C)-Binding Protein 2 Interacts with Sequences Required for Viral Replication in the Hepatitis C Virus (HCV) 5′ Untranslated Region and Directs HCV RNA Replication through Circularizing the Viral Genome ⬇️

artículo científico publicado el 1 de junio de 2011

Polypyrimidine-tract-binding protein affects transcription but not translation of mouse hepatitis virus RNA.

artículo científico publicado en 2002

Polypyrimidine-tract-binding protein is a component of the HCV RNA replication complex and necessary for RNA synthesis

artículo científico publicado en 2006

Pooled RNAi screen identifies ubiquitin ligase Itch as crucial for influenza A virus release from the endosome during virus entry

artículo científico publicado en 2013

Proline-Serine-Threonine Phosphatase-Interacting Protein 2 (PSTPIP2), a Host Membrane-Deforming Protein, Is Critical for Membranous Web Formation in Hepatitis C Virus Replication ⬇️

artículo científico publicado el 30 de noviembre de 2011

Quantitative RT-PCR Analysis of Influenza Virus Endocytic Escape

artículo científico publicado en 2018

RNA replication without RNA-dependent RNA polymerase: surprises from hepatitis delta virus

artículo científico publicado en 2005

RNA-templated replication of hepatitis delta virus: genomic and antigenomic RNAs associate with different nuclear bodies

artículo científico publicado en 2006

Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy.

artículo científico publicado en 2011

Reactive oxygen species suppress hepatitis C virus RNA replication in human hepatoma cells

artículo científico publicado en 2004

Redox modulation of the hepatitis C virus replication complex is calcium dependent

artículo científico publicado en 2006

Rolling circle replication of hepatitis delta virus RNA is carried out by two different cellular RNA polymerases

artículo científico publicado en 2002

SARS virus: the beginning of the unraveling of a new coronavirus

artículo científico publicado en 2003

SUMO Modification Stabilizes Dengue Virus Nonstructural Protein 5 To Support Virus Replication

artículo científico publicado en 2016

SYNCRIP (synaptotagmin-binding, cytoplasmic RNA-interacting protein) is a host factor involved in hepatitis C virus RNA replication

artículo científico publicado en 2009

SYNCRIP, a member of the heterogeneous nuclear ribonucleoprotein family, is involved in mouse hepatitis virus RNA synthesis

artículo científico publicado en 2004

The 8ab protein of SARS-CoV is a luminal ER membrane-associated protein and induces the activation of ATF6.

artículo científico publicado en 2009

The C-terminal transmembrane domain of hepatitis C virus (HCV) RNA polymerase is essential for HCV replication in vivo

artículo científico publicado en 2004

The hepatitis C virus persistence: how to evade the immune system? ⬇️

artículo científico publicado el 1 de abril de 2003

The ubiquitin-proteasome system facilitates the transfer of murine coronavirus from endosome to cytoplasm during virus entry

artículo científico publicado en 2005

Transcription of subgenomic mRNA of hepatitis delta virus requires a modified hepatitis delta antigen that is distinct from antigenomic RNA synthesis

artículo científico publicado en 2008

Transient activation of the PI3K-AKT pathway by hepatitis C virus to enhance viral entry

artículo científico publicado en 2012

Treatment of HCV-related mantle-cell lymphoma with ribavirin and pegylated interferon Alfa

artículo científico publicado en 2003

Ubiquitination and deubiquitination of NP protein regulates influenza A virus RNA replication

artículo científico publicado en 2010

Ubiquitination of the Cytoplasmic Domain of Influenza A Virus M2 Protein is Crucial for Production of Infectious Virus Particles

artículo científico publicado en 2017

Using an Old Drug to Target a New Drug Site: Application of Disulfiram to Target the Zn-Site in HCV NS5A Protein.

artículo científico publicado en 2016

Virus detection and its association with symptoms during influenza-like illness in a sample of healthy adults enrolled in a randomised controlled vaccine trial ⬇️

artículo científico publicado en 2012

Zinc Finger-Containing Cellular Transcription Corepressor ZBTB25 Promotes Influenza Virus RNA Transcription and Is a Target for Zinc Ejector Drugs

artículo científico publicado en 2017

[Hepatitis C virus replication associated with lipid rafts]

artículo científico publicado en 2006

c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide-dependent impairment of oxidative DNA repair.

artículo científico publicado en 2010

Lista de obras de Michael M. C. Lai

A Nucleolar Protein, Ribosomal RNA Processing 1 Homolog B (RRP1B), Enhances the Recruitment of Cellular mRNA in Influenza Virus Transcription

A host susceptibility gene, DR1, facilitates influenza A virus replication by suppressing host innate immunity and enhancing viral RNA replication

Activation of anti-hepatitis C virus responses via Toll-like receptor 7.

Annexin A2 is involved in the formation of hepatitis C virus replication complex on the lipid raft

Association of hepatitis C virus replication complexes with microtubules and actin filaments is dependent on the interaction of NS3 and NS5A

Attenuation of 40S Ribosomal Subunit Abundance Differentially Affects Host and HCV Translation and Suppresses HCV Replication ⬇️

CNOT4-Mediated Ubiquitination of Influenza A Virus Nucleoprotein Promotes Viral RNA Replication

Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts

Critical Role of Virion-Associated Cholesterol and Sphingolipid in Hepatitis C Virus Infection

Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins

Detection and characterization of small and large HDV antigens

Detection of a Novel Unglycosylated Form of Hepatitis C Virus E2 Envelope Protein That Is Located in the Cytosol and Interacts with PKR ⬇️

Enzymatic characterization of the full-length and C-terminally truncated hepatitis C virus RNA polymerases: function of the last 21 amino acids of the C terminus in template binding and RNA synthesis

Establishment of B-cell lymphoma cell lines persistently infected with hepatitis C virus in vivo and in vitro: the apoptotic effects of virus infection

Genomic but not antigenomic hepatitis delta virus RNA is preferentially exported from the nucleus immediately after synthesis and processing

HCV core expression in hepatocytes protects against autoimmune liver injury and promotes liver regeneration in mice

HCV infection enhances Th17 commitment, which could affect the pathogenesis of autoimmune diseases

HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication

Hepatitis C Virus (HCV)-Induced Immunoglobulin Hypermutation Reduces the Affinity and Neutralizing Activities of Antibodies against HCV Envelope Protein

Hepatitis C Virus Causes Uncoupling of Mitotic Checkpoint and Chromosomal Polyploidy through the Rb Pathway

Hepatitis C Virus Genotype 1b Core Protein Does Not Exert Immunomodulatory Effects on Virus-Induced Cellular Immunity ⬇️

Hepatitis C Virus Inhibits DNA Damage Repair through Reactive Oxygen and Nitrogen Species and by Interfering with the ATM-NBS1/Mre11/Rad50 DNA Repair Pathway in Monocytes and Hepatocytes ⬇️

Hepatitis C Virus RNA Replication Occurs on a Detergent-Resistant Membrane That Cofractionates with Caveolin-2

Hepatitis C Virus Triggers Mitochondrial Permeability Transition with Production of Reactive Oxygen Species, Leading to DNA Damage and STAT3 Activation

Hepatitis C virus E2-CD81 interaction induces hypermutation of the immunoglobulin gene in B cells

Hepatitis C virus IRES-dependent translation is insensitive to an eIF2alpha-independent mechanism of inhibition by interferon in hepatocyte cell lines

Hepatitis C virus NS3/4A protein interacts with ATM, impairs DNA repair and enhances sensitivity to ionizing radiation.

Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins

Hepatitis C virus core protein regulates p300/CBP co-activation function. Possible role in the regulation of NF-AT1 transcriptional activity

Hepatitis C virus egress and release depend on endosomal trafficking of core protein

Hepatitis C virus has a genetically determined lymphotropism through co-receptor B7.2.

Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes

Hepatitis C virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon and interleukin-6

Hepatitis C virus infection activates the immunologic (type II) isoform of nitric oxide synthase and thereby enhances DNA damage and mutations of cellular genes

Hepatitis C virus infection of T cells inhibits proliferation and enhances fas-mediated apoptosis by down-regulating the expression of CD44 splicing variant 6.

Hepatitis C virus infects T cells and affects interferon-gamma signaling in T cell lines

Hepatitis C virus nonstructural 5B protein regulates tumor necrosis factor alpha signaling through effects on cellular IkappaB kinase

Hepatitis C virus proteins: direct link to hepatic oxidative stress, steatosis, carcinogenesis and more

Hepatitis C virus translation preferentially depends on active RNA replication

Hepatitis Delta Virus RNA Encoding the Large Delta Antigen Cannot Sustain Replication due to Rapid Accumulation of Mutations Associated with RNA Editing ⬇️

Hepatitis Delta Virus RNA Replication ⬇️

Hepatitis delta virus RNA transfection for the cell culture model

Hepatitis delta virus antigen is methylated at arginine residues, and methylation regulates subcellular localization and RNA replication

High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity

Household transmission of respiratory viruses - assessment of viral, individual and household characteristics in a population study of healthy Australian adults.

How Dengue Virus Circumvents Innate Immunity

Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B

Human monoclonal antibody to hepatitis C virus E1 glycoprotein that blocks virus attachment and viral infectivity

Identification of RNA ligands that bind hepatitis C virus polymerase selectively and inhibit its RNA synthesis from the natural viral RNA templates

Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy ⬇️

Immunogenicity of a monovalent 2009 influenza A(H1N1) vaccine in infants and children: a randomized trial.

Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase

Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft

Involvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A protein

Is avian influenza A (H7N9) virus staggering its way to humans?

Large hepatitis delta antigen is not a suppressor of hepatitis delta virus RNA synthesis once RNA replication is established ⬇️

Modification of small hepatitis delta virus antigen by SUMO protein

Molecular pathogenesis of Gilbert's syndrome: decreased TATA-binding protein binding affinity of UGT1A1 gene promoter

Multiple type A/B heterogeneous nuclear ribonucleoproteins (hnRNPs) can replace hnRNP A1 in mouse hepatitis virus RNA synthesis

Murine Retroviral Pseudotype Virus Containing Hepatitis B Virus Large and Small Surface Antigens Confers Specific Tropism for Primary Human Hepatocytes: a Potential Liver-Specific Targeting System ⬇️

Murine coronavirus requires lipid rafts for virus entry and cell-cell fusion but not for virus release

Mutagenic and inhibitory effects of ribavirin on hepatitis C virus RNA polymerase

Nonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activation

Nonstructural protein 5A is incorporated into hepatitis C virus low-density particle through interaction with core protein and microtubules during intracellular transport

Palmitoylation and Polymerization of Hepatitis C Virus NS4B Protein

Polo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5A

Polo-like-kinase 1: A key cellular target for anti-HBV therapy?

Poly(C)-Binding Protein 2 Interacts with Sequences Required for Viral Replication in the Hepatitis C Virus (HCV) 5′ Untranslated Region and Directs HCV RNA Replication through Circularizing the Viral Genome ⬇️

Polypyrimidine-tract-binding protein affects transcription but not translation of mouse hepatitis virus RNA.

Polypyrimidine-tract-binding protein is a component of the HCV RNA replication complex and necessary for RNA synthesis

Pooled RNAi screen identifies ubiquitin ligase Itch as crucial for influenza A virus release from the endosome during virus entry

Proline-Serine-Threonine Phosphatase-Interacting Protein 2 (PSTPIP2), a Host Membrane-Deforming Protein, Is Critical for Membranous Web Formation in Hepatitis C Virus Replication ⬇️

Quantitative RT-PCR Analysis of Influenza Virus Endocytic Escape

RNA replication without RNA-dependent RNA polymerase: surprises from hepatitis delta virus

RNA-templated replication of hepatitis delta virus: genomic and antigenomic RNAs associate with different nuclear bodies

Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy.

Reactive oxygen species suppress hepatitis C virus RNA replication in human hepatoma cells

Redox modulation of the hepatitis C virus replication complex is calcium dependent

Rolling circle replication of hepatitis delta virus RNA is carried out by two different cellular RNA polymerases