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A Simple Scalable Association Hypothesis Test Combining Gene-wide Evidence From Multiple Polymorphisms

artículo científico

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

scientific journal article

A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry.

artículo científico publicado en 2011

A common variant in the Von Willebrand factor gene is associated with multiple functional consequences.

artículo científico publicado en 2010

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

artículo científico publicado en 2021

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

artículo científico publicado en 2015

Age differences in periventricular and deep white matter lesions.

artículo científico publicado en 2015

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

artículo científico publicado en 2021

Effect of obesity on platelet reactivity and response to low-dose aspirin.

artículo científico publicado en 2010

Effect of white matter lesions on manual dexterity in healthy middle-aged persons

artículo científico publicado en 2015

Ethnic-specific determinants of exercise capacity in a healthy high-risk population

artículo científico publicado en 2012

Extreme deep white matter hyperintensity volumes are associated with African American race

artículo científico publicado en 2014

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

artículo científico publicado en 2016

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

artículo científico publicado en 2012

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

artículo científico publicado en 2014

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

scientific journal article

Glucose levels in the normal range predict incident diabetes in families with premature coronary heart disease

artículo científico publicado en 2006

Greater collagen-induced platelet aggregation following cyclooxygenase 1 inhibition predicts incident acute coronary syndromes

artículo científico publicado en 2014

Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1

artículo científico publicado en 2007

Hypertension Is Associated with White Matter Disruption in Apparently Healthy Middle-Aged Individuals

scientific article published on 15 November 2018

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry

artículo científico publicado en 2011

Impact of a community-based multiple risk factor intervention on cardiovascular risk in black families with a history of premature coronary disease

artículo científico publicado en 2005

Incidence of coronary artery disease in siblings of patients with premature coronary artery disease: 10 years of follow-up.

artículo científico publicado en 2007

Independent metabolic syndrome variants predict new-onset coronary artery disease.

artículo científico publicado en 2010

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

artículo científico publicado en 2020

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

artículo científico publicado en 2010

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

artículo científico publicado en 2019

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

artículo científico publicado en 2016

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

artículo científico publicado en 2013

Native platelet aggregation and response to aspirin in persons with the metabolic syndrome and its components

artículo científico publicado en 2009

Noncalcified coronary plaque volumes in healthy people with a family history of early onset coronary artery disease.

artículo científico publicado en 2014

Platelet inhibition by aspirin 81 and 325 mg/day in men versus women without clinically apparent cardiovascular disease.

artículo científico publicado en 2008

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

artículo científico publicado en 2016

Relation of Plasma Lipoprotein(a) to Subclinical Coronary Plaque Volumes, Three-Vessel and Left Main Coronary Disease, and Severe Coronary Stenoses in Apparently Healthy African-Americans With a Family History of Early-Onset Coronary Artery Disease.

artículo científico publicado en 2016

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

artículo científico publicado en 2019

Severity of inducible myocardial ischemia predicts incident acute coronary syndromes in asymptomatic individuals with a family history of premature coronary artery disease.

artículo científico publicado en 2011

Sex differences in platelet reactivity and response to low-dose aspirin therapy

artículo científico publicado en 2006

Silent myocardial ischaemia and long-term coronary artery disease outcomes in apparently healthy people from families with early-onset ischaemic heart disease

artículo científico publicado en 2011

Silent small-vessel cerebrovascular disease and silent myocardial ischemia in families with premature coronary disease

artículo científico publicado en 2009

The association of brachial artery diameter with noncalcified coronary plaque burden in apparently healthy individuals

artículo científico publicado en 2013

The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans

artículo científico publicado en 2011

The robustness of generalized estimating equations for association tests in extended family data

artículo científico publicado en 2012

Trans-ethnic meta-analysis of white blood cell phenotypes

artículo científico publicado en 2014

Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis

artículo científico publicado en 2023

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

artículo científico publicado en 2019

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

artículo científico publicado en 2019

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

artículo científico publicado en 2016