Lista de obras -

A Unique BSL-3 Cryo-Electron Microscopy Laboratory at UTMB.

artículo científico publicado en 2010

A broad-spectrum antiviral targeting entry of enveloped viruses

artículo científico publicado en 2010

A catalytically and genetically optimized beta-lactamase-matrix based assay for sensitive, specific, and higher throughput analysis of native henipavirus entry characteristics

artículo científico publicado en 2009

A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion

artículo científico publicado en 2013

A replication-incompetent Rift Valley fever vaccine: chimeric virus-like particles protect mice and rats against lethal challenge

artículo científico publicado en 2009

A single sublingual dose of an adenovirus-based vaccine protects against lethal Ebola challenge in mice and guinea pigs

artículo científico publicado en 2011

A single-cycle replicable Rift Valley fever phlebovirus vaccine carrying a mutated NSs confers full protection from lethal challenge in mice

artículo científico publicado en 2018

An assembly model of rift valley Fever virus

artículo científico publicado en 2012

An intersubunit active site between supercoiled parallel beta helices in the trimeric tailspike endorhamnosidase of Shigella flexneri Phage Sf6

artículo científico publicado en 2008

Antiviral effect of ranpirnase against Ebola virus

artículo científico publicado en 2016

Attenuation and protective efficacy of Rift Valley fever phlebovirus rMP12-GM50 strain

artículo científico publicado en 2017

Attenuation of pathogenic Rift Valley fever virus strain through the chimeric S-segment encoding sandfly fever phlebovirus NSs or a dominant-negative PKR.

scientific article published on June 2016

Bolstering Components of the Immune Response Compromised by Prior Exposure to Adenovirus: Guided Formulation Development for a Nasal Ebola Vaccine

artículo científico publicado en 2015

Broad-Range Antiviral Activity of Hydrogen Sulfide Against Highly Pathogenic RNA Viruses

artículo científico publicado en 2017

Characterization of Rift Valley fever virus MP-12 strain encoding NSs of Punta Toro virus or sandfly fever Sicilian virus

artículo científico publicado en 2013

Chemotactic and inflammatory responses in the liver and brain are associated with pathogenesis of Rift Valley fever virus infection in the mouse

artículo científico publicado en 2012

Coagulation factors, fibrinogen and plasminogen activator inhibitor-1, are differentially regulated by yellow fever virus infection of hepatocytes

artículo científico publicado en 2013

Combined chloroquine and ribavirin treatment does not prevent death in a hamster model of Nipah and Hendra virus infection

artículo científico publicado en 2009

Contribution of Human Lung Parenchyma and Leukocyte Influx to Oxidative Stress and Immune System-Mediated Pathology following Nipah Virus Infection

artículo científico publicado en 2017

Cross-neutralisation of viruses of the tick-borne encephalitis complex following tick-borne encephalitis vaccination and/or infection

artículo científico publicado en 2017

Cytokine response in mouse bone marrow derived macrophages after infection with pathogenic and non-pathogenic Rift Valley fever virus

artículo científico publicado en 2015

Detection of severe fever with thrombocytopenia syndrome virus by reverse transcription-cross-priming amplification coupled with vertical flow visualization

artículo científico publicado en 2012

Differential cytokine responses from primary human Kupffer cells following infection with wild-type or vaccine strain yellow fever virus

artículo científico publicado en 2011

Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors

scientific article published on 01 May 2020

Distinct virulence of Rift Valley fever phlebovirus strains from different genetic lineages in a mouse model

artículo científico publicado en 2017

Efficacy and Immunogenicity of a Recombinant Vesicular Stomatitis Virus-Vectored Marburg Vaccine in Cynomolgus Macaques

artículo científico publicado en 2024

Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection

artículo científico publicado en 2017

Efficient and Robust Paramyxoviridae Reverse Genetics Systems.

artículo científico publicado en 2017

Efficient reverse genetics reveals genetic determinants of budding and fusogenic differences between Nipah and Hendra viruses and enables real-time monitoring of viral spread in small animal models of henipavirus infection.

artículo científico publicado en 2014

Establishment and characterization of plasmid-driven minigenome rescue systems for Nipah virus: RNA polymerase I- and T7-catalyzed generation of functional paramyxoviral RNA.

artículo científico publicado en 2007

Evidence for henipavirus spillover into human populations in Africa

artículo científico publicado en 2014

Evidence for ubiquitin-regulated nuclear and subnuclear trafficking among Paramyxovirinae matrix proteins

artículo científico publicado en 2015

Experimental Infection of Syrian Hamsters with Aerosolized Nipah virus

scientific article published on 01 October 2018

Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever

artículo científico publicado en 2013

Favipiravir (T-705) protects against Nipah virus infection in the hamster model.

artículo científico publicado en 2018

Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names

artículo científico publicado en 2014

Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir

artículo científico publicado en 2019

Folding and stability of the leucine-rich repeat domain of internalin B from Listeri monocytogenes

artículo científico publicado en 2004

Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis

scientific article published on 26 August 2020

Genetic subpopulations of Rift Valley fever virus strains ZH548 and MP-12 and recombinant MP-12 strains

artículo científico publicado en 2012

Henipavirus infection of the central nervous system

scientific article published on 01 March 2019

Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines

article

ISG15 deficiency and increased viral resistance in humans but not mice

artículo científico publicado en 2016

Identification of novel cellular targets for therapeutic intervention against Ebola virus infection by siRNA screening

artículo científico publicado en 2009

Imaging of Murine Whole Lung Fibrosis by Large Scale 3D Microscopy aided by Tissue Optical Clearing

artículo científico publicado en 2018

Inactivated or live-attenuated bivalent vaccines that confer protection against rabies and Ebola viruses

artículo científico publicado en 2011

Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol

artículo científico publicado en 2013

Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis

artículo científico publicado en 2021

Modeling pre-existing immunity to adenovirus in rodents: immunological requirements for successful development of a recombinant adenovirus serotype 5-based ebola vaccine

artículo científico publicado en 2013

Multiplexed digital mRNA profiling of the inflammatory response in the West Nile Swiss Webster mouse model

artículo científico publicado en 2014

Mutational analysis of positively charged amino acid residues of Uukuniemi phlebovirus nucleocapsid protein

artículo científico publicado en 2012

N-Glycans on the Rift Valley Fever Virus Envelope Glycoproteins Gn and Gc Redundantly Support Viral Infection via DC-SIGN.

artículo científico publicado en 2016

Natural History and Pathogenesis of Wild-Type Marburg Virus Infection in STAT2 Knockout Hamsters

scholarly article by Colm Atkins et al published 22 November 2018 in Journal of Infectious Diseases

Niemann-Pick C1 Heterogeneity of Bat Cells Controls Filovirus Tropism

scientific article published on 01 January 2020

Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway

artículo científico publicado en 2016

Oligomerization of Uukuniemi virus nucleocapsid protein

artículo científico publicado en 2010

Optimized P2A for reporter gene insertion into Nipah virus results in efficient ribosomal skipping and wild-type lethality

artículo científico publicado en 2016

PHOSPHORYLATED VP30 OF MARBURG VIRUS IS A REPRESSOR OF TRANSCRIPTION

artículo científico publicado en 2018

Peptidoglycan associated cyclic lipopeptide disrupts viral infectivity

artículo científico publicado en 2019

Peptidoglycan-Associated Cyclic Lipopeptide Disrupts Viral Infectivity

scientific article published on 29 October 2019

Phage tailspike proteins with beta-solenoid fold as thermostable carbohydrate binding materials

artículo científico publicado en 2009

Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus

artículo científico publicado en 2008

Polyphenylene carboxymethylene (PPCM) in vitro antiviral efficacy against Ebola virus in the context of a sexually transmitted infection

scientific article published on 24 July 2019

Pyronaridine Tetraphosphate Efficacy Against Ebola Virus Infection in Guinea Pig

artículo científico publicado en 2020

Recent advances in the development of antiviral therapeutics for Rift Valley fever virus infection.

artículo científico publicado en 2017

Recent progress in henipavirus research: molecular biology, genetic diversity, animal models

artículo científico

Recombinant Rift Valley fever vaccines induce protective levels of antibody in baboons and resistance to lethal challenge in mice

artículo científico publicado en 2011

Repurposing Quinacrine against Ebola Virus Infection In Vivo

scientific article published on 23 August 2019

Rift Valley Fever Virus MP-12 Vaccine Is Fully Attenuated by a Combination of Partial Attenuations in the S, M, and L Segments.

artículo científico publicado en 2015

Rift Valley fever virus MP-12 vaccine encoding Toscana virus NSs retains neuroinvasiveness in mice

artículo científico publicado en 2013

Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription

artículo científico publicado en 2014

SAR studies of 4-acyl-1,6-dialkylpiperazin-2-one arenavirus cell entry inhibitors

artículo científico publicado en 2019

SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species

artículo científico publicado en 2020

Single-particle cryo-electron microscopy of Rift Valley fever virus

artículo científico publicado en 2009

Spike mutation D614G alters SARS-CoV-2 fitness

artículo científico publicado en 2020

Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility

artículo científico publicado en 2020

Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility

scientific article published on 10 September 2020

T-705 (favipiravir) inhibition of arenavirus replication in cell culture

artículo científico publicado en 2011

The Dominant-Negative Inhibition of Double-Stranded RNA-Dependent Protein Kinase PKR Increases the Efficacy of Rift Valley Fever Virus MP-12 Vaccine.

artículo científico publicado en 2013

The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication

artículo científico publicado en 2017

The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains

article by Ndongala M. Lubaki et al published 1 November 2013 in Journal of Virology

The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response

artículo científico publicado en 2016

The dominant-negative inhibition of double-stranded RNA-dependent protein kinase PKR increases the efficacy of Rift Valley fever virus MP-12 vaccine

artículo científico publicado en 2012

The lack of maturation of Ebola virus-infected dendritic cells results from the cooperative effect of at least two viral domains

artículo científico publicado en 2013

The tailspike protein of Shigella phage Sf6. A structural homolog of Salmonella phage P22 tailspike protein without sequence similarity in the beta-helix domain.

artículo científico publicado en 2002

Three-Dimensional Organization of Rift Valley Fever Virus Revealed by Cryoelectron Tomography

artículo científico publicado en 2008

Timing of galectin-1 exposure differentially modulates Nipah virus entry and syncytium formation in endothelial cells

artículo científico publicado en 2014

Ubiquitin-regulated nuclear-cytoplasmic trafficking of the Nipah virus matrix protein is important for viral budding

artículo científico publicado en 2010

VAMP8 Contributes to the TRIM6-Mediated Type I Interferon Antiviral Response during West Nile Virus Infection

artículo científico publicado en 2020

Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA

artículo científico publicado en 2013

Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae

artículo científico publicado en 2013

Lista de obras de

A Unique BSL-3 Cryo-Electron Microscopy Laboratory at UTMB.

A broad-spectrum antiviral targeting entry of enveloped viruses

A catalytically and genetically optimized beta-lactamase-matrix based assay for sensitive, specific, and higher throughput analysis of native henipavirus entry characteristics

A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion

A replication-incompetent Rift Valley fever vaccine: chimeric virus-like particles protect mice and rats against lethal challenge

A single sublingual dose of an adenovirus-based vaccine protects against lethal Ebola challenge in mice and guinea pigs

A single-cycle replicable Rift Valley fever phlebovirus vaccine carrying a mutated NSs confers full protection from lethal challenge in mice

An assembly model of rift valley Fever virus

An intersubunit active site between supercoiled parallel beta helices in the trimeric tailspike endorhamnosidase of Shigella flexneri Phage Sf6

Antiviral effect of ranpirnase against Ebola virus

Attenuation and protective efficacy of Rift Valley fever phlebovirus rMP12-GM50 strain

Attenuation of pathogenic Rift Valley fever virus strain through the chimeric S-segment encoding sandfly fever phlebovirus NSs or a dominant-negative PKR.

Bolstering Components of the Immune Response Compromised by Prior Exposure to Adenovirus: Guided Formulation Development for a Nasal Ebola Vaccine

Broad-Range Antiviral Activity of Hydrogen Sulfide Against Highly Pathogenic RNA Viruses

Characterization of Rift Valley fever virus MP-12 strain encoding NSs of Punta Toro virus or sandfly fever Sicilian virus

Chemotactic and inflammatory responses in the liver and brain are associated with pathogenesis of Rift Valley fever virus infection in the mouse

Coagulation factors, fibrinogen and plasminogen activator inhibitor-1, are differentially regulated by yellow fever virus infection of hepatocytes

Combined chloroquine and ribavirin treatment does not prevent death in a hamster model of Nipah and Hendra virus infection

Contribution of Human Lung Parenchyma and Leukocyte Influx to Oxidative Stress and Immune System-Mediated Pathology following Nipah Virus Infection

Cross-neutralisation of viruses of the tick-borne encephalitis complex following tick-borne encephalitis vaccination and/or infection

Cytokine response in mouse bone marrow derived macrophages after infection with pathogenic and non-pathogenic Rift Valley fever virus

Detection of severe fever with thrombocytopenia syndrome virus by reverse transcription-cross-priming amplification coupled with vertical flow visualization

Differential cytokine responses from primary human Kupffer cells following infection with wild-type or vaccine strain yellow fever virus

Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors

Distinct virulence of Rift Valley fever phlebovirus strains from different genetic lineages in a mouse model

Efficacy and Immunogenicity of a Recombinant Vesicular Stomatitis Virus-Vectored Marburg Vaccine in Cynomolgus Macaques

Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection

Efficient and Robust Paramyxoviridae Reverse Genetics Systems.

Efficient reverse genetics reveals genetic determinants of budding and fusogenic differences between Nipah and Hendra viruses and enables real-time monitoring of viral spread in small animal models of henipavirus infection.

Establishment and characterization of plasmid-driven minigenome rescue systems for Nipah virus: RNA polymerase I- and T7-catalyzed generation of functional paramyxoviral RNA.

Evidence for henipavirus spillover into human populations in Africa

Evidence for ubiquitin-regulated nuclear and subnuclear trafficking among Paramyxovirinae matrix proteins

Experimental Infection of Syrian Hamsters with Aerosolized Nipah virus

Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever

Favipiravir (T-705) protects against Nipah virus infection in the hamster model.

Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names

Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir

Folding and stability of the leucine-rich repeat domain of internalin B from Listeri monocytogenes

Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis

Genetic subpopulations of Rift Valley fever virus strains ZH548 and MP-12 and recombinant MP-12 strains

Henipavirus infection of the central nervous system

Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines

ISG15 deficiency and increased viral resistance in humans but not mice

Identification of novel cellular targets for therapeutic intervention against Ebola virus infection by siRNA screening

Imaging of Murine Whole Lung Fibrosis by Large Scale 3D Microscopy aided by Tissue Optical Clearing

Inactivated or live-attenuated bivalent vaccines that confer protection against rabies and Ebola viruses

Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol

Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis

Modeling pre-existing immunity to adenovirus in rodents: immunological requirements for successful development of a recombinant adenovirus serotype 5-based ebola vaccine

Multiplexed digital mRNA profiling of the inflammatory response in the West Nile Swiss Webster mouse model

Mutational analysis of positively charged amino acid residues of Uukuniemi phlebovirus nucleocapsid protein

N-Glycans on the Rift Valley Fever Virus Envelope Glycoproteins Gn and Gc Redundantly Support Viral Infection via DC-SIGN.

Natural History and Pathogenesis of Wild-Type Marburg Virus Infection in STAT2 Knockout Hamsters

Niemann-Pick C1 Heterogeneity of Bat Cells Controls Filovirus Tropism

Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway

Oligomerization of Uukuniemi virus nucleocapsid protein

Optimized P2A for reporter gene insertion into Nipah virus results in efficient ribosomal skipping and wild-type lethality

PHOSPHORYLATED VP30 OF MARBURG VIRUS IS A REPRESSOR OF TRANSCRIPTION

Peptidoglycan associated cyclic lipopeptide disrupts viral infectivity

Peptidoglycan-Associated Cyclic Lipopeptide Disrupts Viral Infectivity

Phage tailspike proteins with beta-solenoid fold as thermostable carbohydrate binding materials

Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus

Polyphenylene carboxymethylene (PPCM) in vitro antiviral efficacy against Ebola virus in the context of a sexually transmitted infection

Pyronaridine Tetraphosphate Efficacy Against Ebola Virus Infection in Guinea Pig

Recent advances in the development of antiviral therapeutics for Rift Valley fever virus infection.

Recent progress in henipavirus research: molecular biology, genetic diversity, animal models

Recombinant Rift Valley fever vaccines induce protective levels of antibody in baboons and resistance to lethal challenge in mice

Repurposing Quinacrine against Ebola Virus Infection In Vivo

Rift Valley Fever Virus MP-12 Vaccine Is Fully Attenuated by a Combination of Partial Attenuations in the S, M, and L Segments.

Rift Valley fever virus MP-12 vaccine encoding Toscana virus NSs retains neuroinvasiveness in mice

Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription

SAR studies of 4-acyl-1,6-dialkylpiperazin-2-one arenavirus cell entry inhibitors

SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species

Single-particle cryo-electron microscopy of Rift Valley fever virus

Spike mutation D614G alters SARS-CoV-2 fitness

Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility

Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility

T-705 (favipiravir) inhibition of arenavirus replication in cell culture

The Dominant-Negative Inhibition of Double-Stranded RNA-Dependent Protein Kinase PKR Increases the Efficacy of Rift Valley Fever Virus MP-12 Vaccine.