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5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.

artículo científico publicado en 2013

A Fluorescent Benzo[g]isoquinoline-based HIF Prolyl Hydroxylase Inhibitor for Cellular Imaging

artículo científico publicado en 2018

A series of potent CREBBP bromodomain ligands reveals an induced-fit pocket stabilized by a cation-π interaction

artículo científico publicado en 2014

Biochemical and biophysical analyses of hypoxia sensing prolyl hydroxylases from Dictyostelium discoideum and Toxoplasma gondii

scientific article published on 15 September 2020

Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains

artículo científico publicado en 2014

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

artículo científico publicado en 2015

Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates

artículo científico publicado en 2010

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

artículo científico publicado en 2017

Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands

artículo científico publicado en 2013

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

artículo científico publicado en 2012

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

artículo científico publicado en 2015

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

artículo científico publicado en 2019

Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases

artículo científico publicado en 2013

Structure-Activity Relationship and Crystallographic Studies on 4-Hydroxypyrimidine HIF Prolyl Hydroxylase Domain Inhibitors

scientific article published on 03 December 2019

Studies on spiro[4.5]decanone prolyl hydroxylase domain inhibitors

scientific article published on 01 March 2019

Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases

artículo científico publicado en 2016

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