Lista de obras -

A luciferase-based screening method for inhibitors of alphavirus replication applied to nucleoside analogues

artículo científico publicado en 2008

Ability of minus strands and modified plus strands to act as templates in Semliki Forest virus RNA replication

artículo científico publicado en 2016

Alphavirus polymerase and RNA replication

artículo científico publicado en 2017

An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication.

scientific article published on August 2016

Assembly of alphavirus replication complexes from RNA and protein components in a novel trans-replication system in mammalian cells

artículo científico publicado en 2011

Betulin-derived compounds as inhibitors of alphavirus replication

artículo científico publicado en 2009

Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex

artículo científico publicado en 2011

Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy.

artículo científico publicado en 2017

Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease's active site cysteine residue.

artículo científico publicado en 2016

Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis

artículo científico publicado en 2015

Correction for Thaa et al., Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.

artículo científico publicado en 2016

Correction: Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy

artículo científico publicado en 2020

Correlative light and electron microscopy enables viral replication studies at the ultrastructural level

artículo científico publicado en 2015

Design and Validation of Novel Chikungunya Virus Protease Inhibitors

artículo científico publicado en 2016

Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.

artículo científico publicado en 2015

Differential activities of cellular and viral macro domain proteins in binding of ADP-ribose metabolites

artículo científico publicado en 2008

Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses

artículo científico publicado en 2016

Early secretory pathway localization and lack of processing for hepatitis E virus replication protein pORF1.

artículo científico publicado en 2012

Enzymatic Defects of the nsP2 Proteins of Semliki Forest Virus Temperature-Sensitive Mutants

artículo científico publicado en 2007

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

artículo científico publicado en 2009

Functions of alphavirus nonstructural proteins in RNA replication

artículo científico publicado en 2002

Identification and Characterization of a Ribose 2'-O-Methyltransferase Encoded by the Ronivirus Branch of Nidovirales

artículo científico publicado en 2016

Identification of Alphavirus Inhibitors by Using Virus-Based Assays and a Chikungunya Replicon Cell Line

artículo científico publicado en 2011

Identification of mutations causing temperature-sensitive defects in Semliki Forest virus RNA synthesis

artículo científico publicado en 2006

Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays

artículo científico publicado en 2011

Inhibitors of virus replication: recent developments and prospects

artículo científico publicado en 2004

Lentiviral vector-derived shRNAs confer enhanced suppression of Semliki forest virus replication in BHK-21 cells compared to shRNAs expressed from plasmids

artículo científico publicado en 2008

Molecular defects caused by temperature-sensitive mutations in Semliki Forest virus nsP1.

artículo científico publicado en 2008

Molecular determinants of substrate specificity for Semliki Forest virus nonstructural protease

artículo científico publicado en 2006

New Phylogenetic Grouping of Positive-Sense RNA Viruses Is Concordant with Replication Complex Morphology

artículo científico publicado en 2019

Obatoclax Inhibits Alphavirus Membrane Fusion by Neutralizing the Acidic Environment of Endocytic Compartments

artículo científico publicado en 2016

Obatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection

artículo científico publicado en 2012

Partially Uncleaved Alphavirus Replicase Forms Spherule Structures in the Presence and Absence of RNA Template

artículo científico publicado en 2017

Phosphatidylinositol 3-kinase-, actin-, and microtubule-dependent transport of Semliki Forest Virus replication complexes from the plasma membrane to modified lysosomes

artículo científico publicado en 2010

Polyprotein Processing as a Determinant for in Vitro Activity of Semliki Forest Virus Replicase

artículo científico publicado en 2017

Purification of highly active alphavirus replication complexes demonstrates altered fractionation of multiple cellular membranes.

artículo científico publicado en 2018

RNA Replication and Membrane Modification Require the Same Functions of Alphavirus Nonstructural Proteins

artículo científico publicado en 2015

Regulation of the sequential processing of Semliki Forest virus replicase polyprotein

artículo científico publicado en 2003

Role of the Amphipathic Peptide of Semliki Forest Virus Replicase Protein nsP1 in Membrane Association and Virus Replication

artículo científico publicado en 2007

SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication

artículo científico publicado en 2011

Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery

scientific article published on 14 June 2019

Sequence analysis reveals a conserved extension in the capping enzyme of the alphavirus supergroup, and a homologous domain in nodaviruses

artículo científico publicado en 2015

Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains

artículo científico publicado en 2006

Structure-function analysis of severe acute respiratory syndrome coronavirus RNA cap guanine-N7-methyltransferase.

artículo científico publicado en 2013

Template RNA length determines the size of replication complex spherules for Semliki Forest virus

artículo científico publicado en 2013

The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling

artículo científico publicado en 2016

The C-terminal repeat domains of nsP3 from the Old World alphaviruses bind directly to G3BP

artículo científico publicado en 2014

The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

artículo científico publicado en 2009

The RNA Capping Enzyme Domain in Protein A is Essential for Flock House Virus Replication

scholarly article by Tania Quirin published in September 2018

Therapeutics and vaccines against chikungunya virus

artículo científico

Treatment of hepatitis C infection: towards eradication of chronic virus

artículo científico publicado el 1 de enero de 2012

Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein

artículo científico publicado en 2016

Lista de obras de

A luciferase-based screening method for inhibitors of alphavirus replication applied to nucleoside analogues

Ability of minus strands and modified plus strands to act as templates in Semliki Forest virus RNA replication

Alphavirus polymerase and RNA replication

An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication.

Assembly of alphavirus replication complexes from RNA and protein components in a novel trans-replication system in mammalian cells

Betulin-derived compounds as inhibitors of alphavirus replication

Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex

Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy.

Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease's active site cysteine residue.

Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis

Correction for Thaa et al., Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.

Correction: Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy

Correlative light and electron microscopy enables viral replication studies at the ultrastructural level

Design and Validation of Novel Chikungunya Virus Protease Inhibitors

Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization.

Differential activities of cellular and viral macro domain proteins in binding of ADP-ribose metabolites

Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses

Early secretory pathway localization and lack of processing for hepatitis E virus replication protein pORF1.

Enzymatic Defects of the nsP2 Proteins of Semliki Forest Virus Temperature-Sensitive Mutants

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

Functions of alphavirus nonstructural proteins in RNA replication

Identification and Characterization of a Ribose 2'-O-Methyltransferase Encoded by the Ronivirus Branch of Nidovirales

Identification of Alphavirus Inhibitors by Using Virus-Based Assays and a Chikungunya Replicon Cell Line

Identification of mutations causing temperature-sensitive defects in Semliki Forest virus RNA synthesis

Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays

Inhibitors of virus replication: recent developments and prospects

Lentiviral vector-derived shRNAs confer enhanced suppression of Semliki forest virus replication in BHK-21 cells compared to shRNAs expressed from plasmids

Molecular defects caused by temperature-sensitive mutations in Semliki Forest virus nsP1.

Molecular determinants of substrate specificity for Semliki Forest virus nonstructural protease

New Phylogenetic Grouping of Positive-Sense RNA Viruses Is Concordant with Replication Complex Morphology

Obatoclax Inhibits Alphavirus Membrane Fusion by Neutralizing the Acidic Environment of Endocytic Compartments

Obatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection

Partially Uncleaved Alphavirus Replicase Forms Spherule Structures in the Presence and Absence of RNA Template

Phosphatidylinositol 3-kinase-, actin-, and microtubule-dependent transport of Semliki Forest Virus replication complexes from the plasma membrane to modified lysosomes

Polyprotein Processing as a Determinant for in Vitro Activity of Semliki Forest Virus Replicase

Purification of highly active alphavirus replication complexes demonstrates altered fractionation of multiple cellular membranes.

RNA Replication and Membrane Modification Require the Same Functions of Alphavirus Nonstructural Proteins

Regulation of the sequential processing of Semliki Forest virus replicase polyprotein

Role of the Amphipathic Peptide of Semliki Forest Virus Replicase Protein nsP1 in Membrane Association and Virus Replication

SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication

Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery

Sequence analysis reveals a conserved extension in the capping enzyme of the alphavirus supergroup, and a homologous domain in nodaviruses

Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains

Structure-function analysis of severe acute respiratory syndrome coronavirus RNA cap guanine-N7-methyltransferase.

Template RNA length determines the size of replication complex spherules for Semliki Forest virus

The Antiviral Alkaloid Berberine Reduces Chikungunya Virus-Induced Mitogen-Activated Protein Kinase Signaling

The C-terminal repeat domains of nsP3 from the Old World alphaviruses bind directly to G3BP

The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

The RNA Capping Enzyme Domain in Protein A is Essential for Flock House Virus Replication

Therapeutics and vaccines against chikungunya virus

Treatment of hepatitis C infection: towards eradication of chronic virus

Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein