Lista de obras -

A heterobivalent ligand inhibits mast cell degranulation via selective inhibition of allergen-IgE interactions in vivo

artículo científico publicado en 2014

A non-chromatographic method for the purification of a bivalently active monoclonal IgG antibody from biological fluids

artículo científico publicado en 2009

A synthetic trivalent hapten that aggregates anti-2,4-DNP IgG into bicyclic trimers

artículo científico publicado en 2007

A systematic analysis of peptide linker length and liposomal polyethylene glycol coating on cellular uptake of peptide-targeted liposomes

artículo científico publicado en 2013

Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding

artículo científico publicado en 2012

Affinity-based precipitation via a bivalent peptidic hapten for the purification of monoclonal antibodies

artículo científico publicado en 2014

Antibody purification via affinity membrane chromatography method utilizing nucleotide binding site targeting with a small molecule.

artículo científico publicado en 2016

Cephalosporin Allergy: Current Understanding and Future Challenges

scientific article published on 01 September 2019

Conjugation of a reactive thiol at the nucleotide binding site for site-specific antibody functionalization.

artículo científico publicado en 2014

Controlling association of vesicle embedded peptides by alteration of the physical state of the lipid matrix

artículo científico publicado en 2005

Covalent Heterobivalent Inhibitor Design for Inhibition of IgE-Dependent Penicillin Allergy in a Murine Model

scientific article published on 17 May 2019

De novo design of defined helical bundles in membrane environments

scholarly article

Dependence of avidity on linker length for a bivalent ligand-bivalent receptor model system

artículo científico publicado en 2011

Design of a heterobivalent ligand to inhibit IgE clustering on mast cells

artículo científico publicado en 2011

Design of a heterotetravalent synthetic allergen that reflects epitope heterogeneity and IgE antibody variability to study mast cell degranulation

artículo científico publicado en 2013

Designer covalent heterobivalent inhibitors prevent IgE-dependent responses to peanut allergen

scientific article published on 08 April 2019

Determination of Crucial Immunogenic Epitopes in Major Peanut Allergy Protein, Ara h2, via Novel Nanoallergen Platform

artículo científico publicado en 2017

Dual Carfilzomib and Doxorubicin-Loaded Liposomal Nanoparticles for Synergistic Efficacy in Multiple Myeloma

artículo científico publicado en 2016

Dual-receptor targeted strategy in nanoparticle design achieves tumor cell selectivity through cooperativity

scientific article published on 01 March 2019

Engineering peptide-targeted liposomal nanoparticles optimized for improved selectivity for HER2-positive breast cancer cells to achieve enhanced in vivo efficacy

artículo científico publicado en 2020

Enhanced cellular uptake of peptide-targeted nanoparticles through increased peptide hydrophilicity and optimized ethylene glycol peptide-linker length

artículo científico publicado en 2013

Fluorinated interfaces drive self-association of transmembrane alpha helices in lipid bilayers

scientific article published on 01 April 2006

Functionalized liposome purification via Liposome Extruder Purification (LEP).

artículo científico publicado en 2013

Harnessing structure-activity relationship to engineer a cisplatin nanoparticle for enhanced antitumor efficacy

artículo científico publicado en 2010

How could nanoallergen technology be used as a diagnostic tool for allergies?

scientific article published on 24 April 2020

Identification of a moderate affinity CD22 binding peptide and in vitro optimization of peptide-targeted nanoparticles for selective uptake by CD22+ B-cell malignancies

artículo científico publicado en 2020

Improved Peptide-Targeted Liposome Design Through Optimized Peptide Hydrophilicity, Ethylene Glycol Linker Length, and Peptide Density

artículo científico publicado en 2015

In vivo evaluation of CD38 and CD138 as targets for nanoparticle-based drug delivery in multiple myeloma

scientific article published on 02 November 2020

Inhibition of weak-affinity epitope-IgE interactions prevents mast cell degranulation

artículo científico publicado en 2013

Ligand-targeted liposome design: challenges and fundamental considerations.

artículo científico publicado en 2013

Liposomal bortezomib nanoparticles via boronic ester prodrug formulation for improved therapeutic efficacy in vivo.

artículo científico publicado en 2014

Liposomal carfilzomib nanoparticles effectively target multiple myeloma cells and demonstrate enhanced efficacy in vivo.

artículo científico publicado en 2014

Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation

artículo científico publicado en 2008

Micellar nanoparticle formation via electrostatic interactions for delivering multinuclear platinum(II) drugs

artículo científico publicado en 2013

Nanoallergen platform for detection of platin drug allergies

artículo científico publicado en 2019

Nanoallergens: A multivalent platform for studying and evaluating potency of allergen epitopes in cellular degranulation

artículo científico publicado en 2016

Neutralizing positive charges at the surface of a protein lowers its rate of amide hydrogen exchange without altering its structure or increasing its thermostability.

artículo científico publicado en 2010

Nonchromatographic affinity precipitation method for the purification of bivalently active pharmaceutical antibodies from biological fluids.

artículo científico publicado en 2013

Optimizing design parameters of a peptide targeted liposomal nanoparticle in an in vivo multiple myeloma disease model after initial evaluation in vitro

scientific article published on 29 August 2019

Oriented Immobilization of Fab Fragments by Site-Specific Biotinylation at the Conserved Nucleotide Binding Site for Enhanced Antigen Detection.

artículo científico publicado en 2015

Oriented antibody immobilization by site-specific UV photocrosslinking of biotin at the conserved nucleotide binding site for enhanced antigen detection

artículo científico publicado en 2013

Oriented surface immobilization of antibodies at the conserved nucleotide binding site for enhanced antigen detection.

artículo científico publicado en 2012

Photosensitive Pt(IV)-azide prodrug-loaded nanoparticles exhibit controlled drug release and enhanced efficacy in vivo

artículo científico publicado en 2014

Polyvalent Nanoobjects for Precision Diagnostics

scientific article published on 27 February 2019

Rationally engineered nanoparticles target multiple myeloma cells, overcome cell-adhesion-mediated drug resistance, and show enhanced efficacy in vivo

artículo científico publicado en 2012

Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site

artículo científico publicado en 2013

Site-specific conjugation of an antibody on a gold nanoparticle surface for one-step diagnosis of prostate specific antigen with dynamic light scattering.

artículo científico publicado en 2017

Site-specific fab fragment biotinylation at the conserved nucleotide binding site for enhanced Ebola detection.

artículo científico publicado en 2015

Small-molecule-based affinity chromatography method for antibody purification via nucleotide binding site targeting

artículo científico publicado en 2012

Supramolecular Assemblies for Macrophage Activation in Cancer Therapy

artículo científico publicado en 2018

Synthetic allergen design reveals the significance of moderate affinity epitopes in mast cell degranulation.

artículo científico publicado en 2012

Two-allergen model reveals complex relationship between IgE crosslinking and degranulation

artículo científico publicado en 2014

What potential do heterobivalent inhibitors have for the treatment of severe allergic reactions?

artículo científico publicado en 2014

Lista de obras de

A heterobivalent ligand inhibits mast cell degranulation via selective inhibition of allergen-IgE interactions in vivo

A non-chromatographic method for the purification of a bivalently active monoclonal IgG antibody from biological fluids

A synthetic trivalent hapten that aggregates anti-2,4-DNP IgG into bicyclic trimers

A systematic analysis of peptide linker length and liposomal polyethylene glycol coating on cellular uptake of peptide-targeted liposomes

Abnormal SDS-PAGE migration of cytosolic proteins can identify domains and mechanisms that control surfactant binding

Affinity-based precipitation via a bivalent peptidic hapten for the purification of monoclonal antibodies

Antibody purification via affinity membrane chromatography method utilizing nucleotide binding site targeting with a small molecule.

Cephalosporin Allergy: Current Understanding and Future Challenges

Conjugation of a reactive thiol at the nucleotide binding site for site-specific antibody functionalization.

Controlling association of vesicle embedded peptides by alteration of the physical state of the lipid matrix

Covalent Heterobivalent Inhibitor Design for Inhibition of IgE-Dependent Penicillin Allergy in a Murine Model

De novo design of defined helical bundles in membrane environments

Dependence of avidity on linker length for a bivalent ligand-bivalent receptor model system

Design of a heterobivalent ligand to inhibit IgE clustering on mast cells

Design of a heterotetravalent synthetic allergen that reflects epitope heterogeneity and IgE antibody variability to study mast cell degranulation

Designer covalent heterobivalent inhibitors prevent IgE-dependent responses to peanut allergen

Determination of Crucial Immunogenic Epitopes in Major Peanut Allergy Protein, Ara h2, via Novel Nanoallergen Platform

Dual Carfilzomib and Doxorubicin-Loaded Liposomal Nanoparticles for Synergistic Efficacy in Multiple Myeloma

Dual-receptor targeted strategy in nanoparticle design achieves tumor cell selectivity through cooperativity

Engineering peptide-targeted liposomal nanoparticles optimized for improved selectivity for HER2-positive breast cancer cells to achieve enhanced in vivo efficacy

Enhanced cellular uptake of peptide-targeted nanoparticles through increased peptide hydrophilicity and optimized ethylene glycol peptide-linker length

Fluorinated interfaces drive self-association of transmembrane alpha helices in lipid bilayers

Functionalized liposome purification via Liposome Extruder Purification (LEP).

Harnessing structure-activity relationship to engineer a cisplatin nanoparticle for enhanced antitumor efficacy

How could nanoallergen technology be used as a diagnostic tool for allergies?

Identification of a moderate affinity CD22 binding peptide and in vitro optimization of peptide-targeted nanoparticles for selective uptake by CD22+ B-cell malignancies

Improved Peptide-Targeted Liposome Design Through Optimized Peptide Hydrophilicity, Ethylene Glycol Linker Length, and Peptide Density

In vivo evaluation of CD38 and CD138 as targets for nanoparticle-based drug delivery in multiple myeloma

Inhibition of weak-affinity epitope-IgE interactions prevents mast cell degranulation

Ligand-targeted liposome design: challenges and fundamental considerations.

Liposomal bortezomib nanoparticles via boronic ester prodrug formulation for improved therapeutic efficacy in vivo.

Liposomal carfilzomib nanoparticles effectively target multiple myeloma cells and demonstrate enhanced efficacy in vivo.

Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation

Micellar nanoparticle formation via electrostatic interactions for delivering multinuclear platinum(II) drugs

Nanoallergen platform for detection of platin drug allergies

Nanoallergens: A multivalent platform for studying and evaluating potency of allergen epitopes in cellular degranulation

Neutralizing positive charges at the surface of a protein lowers its rate of amide hydrogen exchange without altering its structure or increasing its thermostability.

Nonchromatographic affinity precipitation method for the purification of bivalently active pharmaceutical antibodies from biological fluids.

Optimizing design parameters of a peptide targeted liposomal nanoparticle in an in vivo multiple myeloma disease model after initial evaluation in vitro

Oriented Immobilization of Fab Fragments by Site-Specific Biotinylation at the Conserved Nucleotide Binding Site for Enhanced Antigen Detection.

Oriented antibody immobilization by site-specific UV photocrosslinking of biotin at the conserved nucleotide binding site for enhanced antigen detection

Oriented surface immobilization of antibodies at the conserved nucleotide binding site for enhanced antigen detection.

Photosensitive Pt(IV)-azide prodrug-loaded nanoparticles exhibit controlled drug release and enhanced efficacy in vivo

Polyvalent Nanoobjects for Precision Diagnostics

Rationally engineered nanoparticles target multiple myeloma cells, overcome cell-adhesion-mediated drug resistance, and show enhanced efficacy in vivo

Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site

Site-specific conjugation of an antibody on a gold nanoparticle surface for one-step diagnosis of prostate specific antigen with dynamic light scattering.

Site-specific fab fragment biotinylation at the conserved nucleotide binding site for enhanced Ebola detection.

Small-molecule-based affinity chromatography method for antibody purification via nucleotide binding site targeting

Supramolecular Assemblies for Macrophage Activation in Cancer Therapy

Synthetic allergen design reveals the significance of moderate affinity epitopes in mast cell degranulation.

Two-allergen model reveals complex relationship between IgE crosslinking and degranulation

What potential do heterobivalent inhibitors have for the treatment of severe allergic reactions?