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10th Anniversary Perspective: Reflections on endocrine disruption in the aquatic environment: from known knowns to unknown unknowns (and many things in between).

artículo científico publicado en 2008

5α-Dihydrotestosterone is a potent androgen in the fathead minnow (Pimephales promelas).

artículo científico

A rational approach to selecting and ranking some pharmaceuticals of concern for the aquatic environment and their relative importance compared with other chemicals

artículo científico publicado en 2015

A restatement of the natural science evidence base on the effects of endocrine disrupting chemicals on wildlife

artículo científico publicado en 2019

Accurate prediction of the response of freshwater fish to a mixture of estrogenic chemicals

artículo científico publicado en 2005

An alternative approach to risk rank chemicals on the threat they pose to the aquatic environment

artículo científico publicado en 2017

Anti-anxiety drugs and fish behavior: Establishing the link between internal concentrations of oxazepam and behavioral effects.

artículo científico publicado en 2016

Are some invertebrates exquisitely sensitive to the human pharmaceutical fluoxetine?

artículo científico publicado en 2013

Are we going about chemical risk assessment for the aquatic environment the wrong way?

artículo científico publicado en 2016

Assessing the concentrations and risks of toxicity from the antibiotics ciprofloxacin, sulfamethoxazole, trimethoprim and erythromycin in European rivers.

artículo científico publicado en 2015

Assessing the concentrations of polar organic microcontaminants from point sources in the aquatic environment: measure or model?

artículo científico publicado en 2008

Benzotriazole is antiestrogenic in vitro but not in vivo.

artículo científico publicado en 2007

COMPREHENDing endocrine disrupters in aquatic environments.

artículo científico publicado en 2003

Changes in estrogenic and androgenic activities at different stages of treatment in wastewater treatment works

artículo científico publicado en 2002

Characterisation and expression of β1-, β2- and β3-adrenergic receptors in the fathead minnow (Pimephales promelas).

artículo científico publicado en 2011

Chronic effects assessment and plasma concentrations of the beta-blocker propranolol in fathead minnows (Pimephales promelas).

artículo científico

Comments on Niemuth, N.J. and Klaper, R.D. 2015. Emerging wastewater contaminant metformin causes intersex and reduced fecundity in fish. Chemosphere 135, 38–45

artículo científico publicado en 2016

Comparative physiology, pharmacology and toxicology of beta-blockers: mammals versus fish

artículo científico publicado en 2007

Corrigendum: Internal exposure dynamics drive the Adverse Outcome Pathways of synthetic glucocorticoids in fish

artículo científico publicado en 2016

Could the Quality of Published Ecotoxicological Research Be Better?

artículo científico publicado en 2015

Defining the chronic impacts of atenolol on embryo-larval development and reproduction in the fathead minnow (Pimephales promelas).

artículo científico publicado en 2007

Derivation of an aquatic predicted no-effect concentration for the synthetic hormone, 17 alpha-ethinyl estradiol.

artículo científico publicado en 2008

Diclofenac: New data on chronic toxicity and bioconcentration in fish

artículo científico publicado en 2013

Do concentrations of ethinylestradiol, estradiol, and diclofenac in European rivers exceed proposed EU environmental quality standards?

artículo científico publicado en 2013

Do cytotoxic chemotherapy drugs discharged into rivers pose a risk to the environment and human health? An overview and UK case study

article

Do suspended sediments modulate the effects of octylphenol on rainbow trout?

artículo científico publicado en 2008

Drug residues and endocrine disruptors in drinking water: risk for humans?

artículo científico

Ecotoxicology--a multidisciplinary, problem-driven science

scientific article published on 01 December 2004

Effects of low concentrations of the antiprogestin mifepristone (RU486) in adults and embryos of zebrafish (Danio rerio): 1. Reproductive and early developmental effects

artículo científico publicado en 2013

Effects of low concentrations of the antiprogestin mifepristone (RU486) in adults and embryos of zebrafish (Danio rerio): 2. Gene expression analysis and in vitro activity

Effects of the synthetic estrogen 17α-ethinylestradiol on the life-cycle of the fathead minnow (Pimephales promelas)

article

Endocrine (sexual) disruption is not a prominent feature in the pike (Esox lucius), a top predator, living in English waters.

artículo científico publicado en 2005

Endocrine Disrupters in the Aquatic Environment: An Overview

article

Endocrine disruption due to estrogens derived from humans predicted to be low in the majority of U.S. surface waters.

artículo científico publicado en 2012

Estrogenic activity measured in a sewage treatment works treating industrial inputs containing high concentrations of alkylphenolic compounds--a case study

artículo científico publicado en 2002

Estrogenic activity of tropical fish food can alter baseline vitellogenin concentrations in male fathead minnow (Pimephales promelas)

artículo científico publicado el 4 de marzo de 2011

Estrogenic potency of effluent from two sewage treatment works in the United Kingdom

article

Evidence of estrogenic mixture effects on the reproductive performance of fish

artículo científico publicado en 2007

Evidence of temperature-dependent effects on the estrogenic response of fish: implications with regard to climate change

artículo científico publicado en 2008

Evidence suggesting that di-n-butyl phthalate has antiandrogenic effects in fish

artículo científico publicado en 2011

Exposure assessment of 17alpha-ethinylestradiol in surface waters of the United States and Europe.

scientific article published on December 2009

From dishwasher to tap? Xenobiotic substances benzotriazole and tolyltriazole in the environment

artículo científico publicado en 2011

From single chemicals to mixtures--reproductive effects of levonorgestrel and ethinylestradiol on the fathead minnow

artículo científico publicado en 2015

Hypoxia does not influence the response of fish to a mixture of estrogenic chemicals.

artículo científico publicado en 2009

Identification and quantification of 5α-dihydrotestosterone in the teleost fathead minnow (Pimephales promelas) by gas chromatography-tandem mass spectrometry

artículo científico publicado en 2013

Immunoassays are not immune to errors: Examples from two studies of steroid output from freshwater trout farms

scientific article published on 30 July 2019

Impaired reproduction in three-spined sticklebacks exposed to ethinyl estradiol as juveniles

artículo científico publicado en 2007

Improving environmental risk assessment of human pharmaceuticals

artículo científico publicado en 2015

Improving environmental risk assessments of chemicals: Steps towards evidence-based ecotoxicology

scientific article published on 03 May 2019

Improving the quality of wastewater to tackle trace organic contaminants: think before you act!

artículo científico publicado en 2015

In Response: An academic perspective

artículo científico publicado en 2016

In vivo and in vitro liver and gill EROD activity in rainbow trout (Oncorhynchus mykiss) exposed to the beta-blocker propranolol.

artículo científico publicado en 2011

In vivo ovarian uptake and processing of vitellogenin in the rainbow trout,Salmo gairdneri

article

Internal exposure dynamics drive the Adverse Outcome Pathways of synthetic glucocorticoids in fish.

artículo científico publicado en 2016

Isomer-specific degradation and endocrine disrupting activity of nonylphenols

artículo científico publicado en 2008

Key actions for a sustainable chemicals policy

scientific article published on 18 February 2020

Learning from the past and considering the future of chemicals in the environment

artículo científico publicado en 2020

Lessons from endocrine disruption and their application to other issues concerning trace organics in the aquatic environment

artículo científico publicado en 2005

Long-Term Temporal Changes in the Estrogenic Composition of Treated Sewage Effluent and Its Biological Effects on Fish

article

Medicating the environment: assessing risks of pharmaceuticals to wildlife and ecosystems.

artículo científico publicado en 2014

Metabolic and reproductive effects of relatively low concentrations of beclomethasone dipropionate, a synthetic glucocorticoid, on fathead minnows

artículo científico publicado en 2013

Metabolism and environmental degradation of pyrethroid insecticides produce compounds with endocrine activities

article

Mode of action of human pharmaceuticals in fish: the effects of the 5-alpha-reductase inhibitor, dutasteride, on reproduction as a case study.

artículo científico publicado en 2012

Modeling Effects of Mixtures of Endocrine Disrupting Chemicals at the River Catchment Scale

article

Populations of a cyprinid fish are self-sustaining despite widespread feminization of males

artículo científico publicado en 2014

Predicted-no-effect concentrations for the steroid estrogens estrone, 17β-estradiol, estriol, and 17α-ethinylestradiol

artículo científico publicado en 2012

Predicting concentrations of the cytostatic drugs cyclophosphamide, carboplatin, 5-fluorouracil, and capecitabine throughout the sewage effluents and surface waters of Europe

artículo científico publicado en 2013

Prediction of environmental concentrations of glucocorticoids: the River Thames, UK, as an example

artículo científico publicado en 2011

Preliminary studies into the effects of the human pharmaceutical Clofibric acid on sperm parameters in adult Fathead minnow

artículo científico publicado en 2007

Principles of sound ecotoxicology

artículo científico publicado en 2014

Progesterone potentially degrades to potent androgens in surface waters

artículo científico publicado en 2016

Progress and promises in toxicogenomics in aquatic toxicology: is technical innovation driving scientific innovation?

artículo científico

Protecting aquatic organisms from chemicals: the harsh realities

artículo científico publicado en 2009

Protecting the environment from psychoactive drugs: Problems for regulators illustrated by the possible effects of tramadol on fish behaviour

artículo científico publicado en 2019

Putting pharmaceuticals into the wider context of challenges to fish populations in rivers.

artículo científico publicado en 2014

Quantitative cross-species extrapolation between humans and fish: the case of the anti-depressant fluoxetine

artículo científico publicado en 2014

Reduction in the estrogenic activity of a treated sewage effluent discharge to an English river as a result of a decrease in the concentration of industrially derived surfactants

artículo científico publicado en 2002

Relative potencies and combination effects of steroidal estrogens in fish

artículo científico publicado en 2003

Renewing and improving the environmental risk assessment of chemicals

artículo científico publicado en 2022

Repeating history: pharmaceuticals in the environment.

artículo científico publicado en 2007

Reproductive responses in fathead minnow and Japanese medaka following exposure to a synthetic progestin, Norethindrone

artículo científico publicado en 2010

Route of exposure affects the oestrogenic response of fish to 4-tert-nonylphenol.

artículo científico publicado en 2003

Scientific integrity issues in Environmental Toxicology and Chemistry: Improving research reproducibility, credibility, and transparency

artículo científico publicado en 2019

Selectivity of protein sequestration by vitellogenic oocytes of the rainbow trout,Salmo gairdneri

article

Several synthetic progestins with different potencies adversely affect reproduction of fish

artículo científico publicado en 2013

Sexual disruption in a second species of wild cyprinid fish (the gudgeon,Gobio gobio) in United Kingdom Freshwaters

scholarly article by Ronny van Aerle published in December 2001

Stress status of gudgeon (Gobio gobio) from rivers in Switzerland with and without input of sewage treatment plant effluent.

artículo científico publicado en 2003

Synthetic Glucocorticoids in the Environment: First Results on Their Potential Impacts on Fish

artículo científico publicado el 15 de febrero de 2011

THE STRESS RESPONSE AND ITS CONSEQUENCES IN CULTURED FISH

artículo científico publicado en 1991

Targeting the environmental risk assessment of pharmaceuticals: Facts and fantasies

artículo científico publicado en 2010

Testing the "read-across hypothesis" by investigating the effects of ibuprofen on fish

artículo científico publicado en 2016

The British river of the future: how climate change and human activity might affect two contrasting river ecosystems in England

artículo científico publicado en 2009

The challenge: Do pharmaceuticals present a risk to the environment, and what needs to be done to answer the question?

article published in 2014

The consequences of exposure to mixtures of chemicals: Something from 'nothing' and 'a lot from a little' when fish are exposed to steroid hormones

artículo científico publicado en 2017

The consequences of feminization in breeding groups of wild fish.

artículo científico publicado en 2011

The development of a radioimmunoassay for carp, Cyprinus carpio, vitellogenin

article

The ecotoxicology of hormonally active micropollutants

artículo científico publicado en 2008

The influence of a surfactant, linear alkylbenzene sulfonate, on the estrogenic response to a mixture of (xeno)estrogens in vitro and in vivo

artículo científico publicado en 2008

The occurrence, causes, and consequences of estrogens in the aquatic environment

artículo científico publicado en 2013

The read-across hypothesis and environmental risk assessment of pharmaceuticals.

artículo científico publicado en 2013

The role of the North Atlantic Oscillation in controlling U.K. butterfly population size and phenology

artículo científico publicado en 2012

The value of repeating studies and multiple controls: replicated 28-day growth studies of rainbow trout exposed to clofibric acid

artículo científico publicado en 2010

Towards improved behavioural testing in aquatic toxicology: Acclimation and observation times are important factors when designing behavioural tests with fish

artículo científico publicado en 2017

Uptake and Metabolism of Human Pharmaceuticals by Fish: A Case Study with the Opioid Analgesic Tramadol

artículo científico publicado en 2017

Uptake of propranolol, a cardiovascular pharmaceutical, from water into fish plasma and its effects on growth and organ biometry.

artículo científico publicado en 2009

Using risk-ranking of metals to identify which poses the greatest threat to freshwater organisms in the UK.

artículo científico publicado en 2014

Utility of a juvenile fathead minnow screening assay for detecting (anti-)estrogenic substances.

artículo científico publicado en 2002

What Makes a Concentration Environmentally Relevant? Critique and a Proposal

artículo científico publicado en 2017

What makes a good scientist? Karl Fent as an example

scientific article published on 11 May 2019

What training and skills will the ecotoxicologists of the future require?

artículo científico publicado en 2016

Widespread Sexual Disruption in Wild Fish

article