Lista de obras -

A novel chymase inhibitor, 2-(5-formylamino-6-oxo-2-phenyl-1,6-dihydropyrimidine-1-yl)-N-[[,4-dioxo-1-phenyl-7-(2-pyridyloxy)]2-heptyl]acetamide (NK3201), suppressed intimal hyperplasia after balloon injury

artículo científico publicado en 2003

A novel chymase inhibitor, 4-[1-([bis-(4-methyl-phenyl)-methyl]-carbamoyl)3-(2-ethoxy-benzyl)-4-oxo-azetidine-2-yloxy]-benzoic acid (BCEAB), suppressed cardiac fibrosis in cardiomyopathic hamsters

artículo científico publicado en 2003

A single treatment with a specific chymase inhibitor, TY-51184, prevents vascular proliferation in canine grafted veins

artículo científico publicado en 2004

A specific chymase inhibitor, 2-(5-formylamino-6-oxo-2-phenyl-1,6-dihydropyrimidine-1-yl)-N-[[3,4-dioxo-1-phenyl-7-(2-pyridyloxy)]-2-heptyl]acetamide (NK3201), suppresses development of abdominal aortic aneurysm in hamsters

artículo científico publicado en 2004

A specific chymase inhibitor, NK3201, suppresses bleomycin-induced pulmonary fibrosis in hamsters

artículo científico publicado en 2004

An antiarrhythmic effect of a chymase inhibitor after myocardial infarction

artículo científico publicado en 2004

Anti-atherosclerotic effects of dihomo-gamma-linolenic acid in ApoE-deficient mice.

artículo científico publicado en 2009

Beneficial effects of angiotensin-converting enzyme inhibition in adriamycin-induced cardiomyopathy in hamsters

artículo científico publicado en 2002

Beneficial effects of cardiac chymase inhibition during the acute phase of myocardial infarction

artículo científico publicado en 2002

Bone Marrow Monocyte Lineage Cells Adhere on Injured Endothelium in a Monocyte Chemoattractant Protein-1–Dependent Manner and Accelerate Reendothelialization as Endothelial Progenitor Cells ⬇️

artículo científico publicado el 2 de octubre de 2003

Candesartan and amlodipine combination therapy provides powerful vascular protection in stroke-prone spontaneously hypertensive rats

artículo científico publicado en 2010

Central role of calcium-dependent tyrosine kinase PYK2 in endothelial nitric oxide synthase-mediated angiogenic response and vascular function

scientific journal article

Chymase as a novel target for the prevention of vascular diseases

artículo científico publicado en 2004

Chymase inhibition attenuates tetrachloride-induced liver fibrosis in hamsters

artículo científico publicado en 2010

Chymase inhibition improves vascular dysfunction and survival in stroke-prone spontaneously hypertensive rats

artículo científico publicado en 2014

Chymase inhibition provides pancreatic islet protection in hamsters with streptozotocin-induced diabetes

artículo científico publicado en 2009

Chymase inhibitor prevents the nonalcoholic steatohepatitis in hamsters fed a methionine- and choline-deficient diet

artículo científico publicado en 2010

Chymase-derived angiotensin II and arrhythmias after myocardial infarction

artículo científico publicado en 2004

Combination therapy with irbesartan and efonidipine for attenuation of proteinuria in Dahl salt-sensitive rats

artículo científico publicado en 2010

Comparative effects of candesartan and amlodipine in a monkey atherosclerotic model

artículo científico publicado en 2004

Decrease in number of mast cells in resected nasal polyps as an indicator for postoperative recurrence of chronic rhinosinusitis

scientific article published on 17 June 2019

Effect of chymase inhibition on the arteriovenous fistula stenosis in dogs

artículo científico publicado en 2005

Effects of Gelatin Hydrogel Containing Anti-Transforming Growth Factor-β Antibody in a Canine Filtration Surgery Model.

artículo científico publicado en 2017

Effects of mitomycin C on the expression of chymase and mast cells in the conjunctival scar of a monkey trabeculectomy model

artículo científico publicado en 2009

Human chymase degrades human fibronectin

artículo científico publicado en 2004

Impact of chymase inhibitor on cardiac function and survival after myocardial infarction ⬇️

artículo científico publicado el 1 de noviembre de 2003

Improvement of cardiovascular remodelling by chymase inhibitor

artículo científico publicado en 2016

Increased local angiotensin II formation in aneurysmal aorta

artículo científico publicado en 2002

Lengthy suppression of vascular proliferation by a chymase inhibitor in dog grafted veins

artículo científico publicado en 2002

New Approaches to Blockade of the Renin–Angiotensin–Aldosterone System: Chymase as an Important Target to Prevent Organ Damage ⬇️

artículo científico publicado el 27 de julio de 2010

Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice

artículo científico publicado en 2005

Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models

artículo científico publicado en 2006

Possible roles of mast cell-derived chymase for skin rejuvenation

artículo científico publicado en 2008

Powerful vascular protection by combining cilnidipine with valsartan in stroke-prone, spontaneously hypertensive rats

artículo científico publicado en 2012

Quantification of Candesartan in Mouse Plasma by MALDI-TOFMS and in Tissue Sections by MALDI-Imaging Using the Stable-Isotope Dilution Technique

artículo científico publicado en 2013

Recombinant human soluble thrombomodulin improved lipopolysaccharide/d-galactosamine-induced acute liver failure in mice

artículo científico publicado en 2015

Significance of angiotensin II receptor blockers with high affinity to angiotensin II type 1 receptors for vascular protection in rats

artículo científico publicado en 2009

Significance of chymase-dependent matrix metalloproteinase-9 activation on indomethacin-induced small intestinal damages in rats

artículo científico publicado en 2009

Significance of matrix metalloproteinase-9 inhibition by imidapril for prevention of abdominal aortic aneurysms in angiotensin II type 1 receptor-knockout mice

artículo científico publicado en 2013

Significance of the vascular concentration of angiotensin II-receptor blockers on the mechanism of lowering blood pressure in spontaneously hypertensive rats

artículo científico publicado en 2013

Significant target organs for hypertension and cardiac hypertrophy by angiotensin-converting enzyme inhibitors

artículo científico publicado en 2004

Targets of chymase inhibitors

scientific article published on 04 February 2011

Therapeutic applications of chymase inhibitors in cardiovascular diseases and fibrosis

artículo científico publicado en 2004

Lista de obras de

A novel chymase inhibitor, 2-(5-formylamino-6-oxo-2-phenyl-1,6-dihydropyrimidine-1-yl)-N-[[,4-dioxo-1-phenyl-7-(2-pyridyloxy)]2-heptyl]acetamide (NK3201), suppressed intimal hyperplasia after balloon injury

A novel chymase inhibitor, 4-[1-([bis-(4-methyl-phenyl)-methyl]-carbamoyl)3-(2-ethoxy-benzyl)-4-oxo-azetidine-2-yloxy]-benzoic acid (BCEAB), suppressed cardiac fibrosis in cardiomyopathic hamsters

A single treatment with a specific chymase inhibitor, TY-51184, prevents vascular proliferation in canine grafted veins

A specific chymase inhibitor, 2-(5-formylamino-6-oxo-2-phenyl-1,6-dihydropyrimidine-1-yl)-N-[[3,4-dioxo-1-phenyl-7-(2-pyridyloxy)]-2-heptyl]acetamide (NK3201), suppresses development of abdominal aortic aneurysm in hamsters

A specific chymase inhibitor, NK3201, suppresses bleomycin-induced pulmonary fibrosis in hamsters

An antiarrhythmic effect of a chymase inhibitor after myocardial infarction

Anti-atherosclerotic effects of dihomo-gamma-linolenic acid in ApoE-deficient mice.

Beneficial effects of angiotensin-converting enzyme inhibition in adriamycin-induced cardiomyopathy in hamsters

Beneficial effects of cardiac chymase inhibition during the acute phase of myocardial infarction

Bone Marrow Monocyte Lineage Cells Adhere on Injured Endothelium in a Monocyte Chemoattractant Protein-1–Dependent Manner and Accelerate Reendothelialization as Endothelial Progenitor Cells ⬇️

Candesartan and amlodipine combination therapy provides powerful vascular protection in stroke-prone spontaneously hypertensive rats

Central role of calcium-dependent tyrosine kinase PYK2 in endothelial nitric oxide synthase-mediated angiogenic response and vascular function

Chymase as a novel target for the prevention of vascular diseases

Chymase inhibition attenuates tetrachloride-induced liver fibrosis in hamsters

Chymase inhibition improves vascular dysfunction and survival in stroke-prone spontaneously hypertensive rats

Chymase inhibition provides pancreatic islet protection in hamsters with streptozotocin-induced diabetes

Chymase inhibitor prevents the nonalcoholic steatohepatitis in hamsters fed a methionine- and choline-deficient diet

Chymase-derived angiotensin II and arrhythmias after myocardial infarction

Combination therapy with irbesartan and efonidipine for attenuation of proteinuria in Dahl salt-sensitive rats

Comparative effects of candesartan and amlodipine in a monkey atherosclerotic model

Decrease in number of mast cells in resected nasal polyps as an indicator for postoperative recurrence of chronic rhinosinusitis

Effect of chymase inhibition on the arteriovenous fistula stenosis in dogs

Effects of Gelatin Hydrogel Containing Anti-Transforming Growth Factor-β Antibody in a Canine Filtration Surgery Model.

Effects of mitomycin C on the expression of chymase and mast cells in the conjunctival scar of a monkey trabeculectomy model

Human chymase degrades human fibronectin

Impact of chymase inhibitor on cardiac function and survival after myocardial infarction ⬇️

Improvement of cardiovascular remodelling by chymase inhibitor

Increased local angiotensin II formation in aneurysmal aorta

Lengthy suppression of vascular proliferation by a chymase inhibitor in dog grafted veins

New Approaches to Blockade of the Renin–Angiotensin–Aldosterone System: Chymase as an Important Target to Prevent Organ Damage ⬇️

Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice

Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models

Possible roles of mast cell-derived chymase for skin rejuvenation

Powerful vascular protection by combining cilnidipine with valsartan in stroke-prone, spontaneously hypertensive rats

Quantification of Candesartan in Mouse Plasma by MALDI-TOFMS and in Tissue Sections by MALDI-Imaging Using the Stable-Isotope Dilution Technique

Recombinant human soluble thrombomodulin improved lipopolysaccharide/d-galactosamine-induced acute liver failure in mice

Significance of angiotensin II receptor blockers with high affinity to angiotensin II type 1 receptors for vascular protection in rats

Significance of chymase-dependent matrix metalloproteinase-9 activation on indomethacin-induced small intestinal damages in rats

Significance of matrix metalloproteinase-9 inhibition by imidapril for prevention of abdominal aortic aneurysms in angiotensin II type 1 receptor-knockout mice

Significance of the vascular concentration of angiotensin II-receptor blockers on the mechanism of lowering blood pressure in spontaneously hypertensive rats

Significant target organs for hypertension and cardiac hypertrophy by angiotensin-converting enzyme inhibitors

Targets of chymase inhibitors

Therapeutic applications of chymase inhibitors in cardiovascular diseases and fibrosis