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An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups.

artículo científico publicado en 2018

Biased modulators of NMDA receptors control channel opening and ion selectivity

scientific article published on 20 January 2020

Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of <i>N</i>-Methyl-d-aspartate Receptors

artículo científico publicado en 2020

Negative allosteric modulation of GluN1/GluN3 NMDA receptors

scientific article published on 07 May 2020

The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors.

artículo científico publicado en 2017

The bioactive protein-ligand conformation of GluN2C-selective positive allosteric modulators bound to the NMDA receptor.

artículo científico publicado en 2017

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