Lista de obras -

A phosphodiesterase 2A isoform localized to mitochondria regulates respiration

scientific journal article

AMPA Induces NO-Dependent cGMP Signals in Hippocampal and Cortical Neurons via L-Type Voltage-Gated Calcium Channels

artículo científico publicado en 2019

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017

article

Activation of PDE10 and PDE11 Phosphodiesterases ⬇️

artículo científico publicado el 21 de noviembre de 2011

Activation of PDE10 and PDE11.

artículo científico publicado en 2011

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

artículo científico publicado en 2010

Analysis of cGMP signalling with transgenic mice expressing FRET-based cGMP sensors

artículo científico publicado en 2013

Angiotensin II-Induced Hypertension Is Attenuated by Reduction of Sympathetic Output in NO-Sensitive Guanylyl Cyclase 1 Knockout Mice

artículo científico publicado en 2015

Bioactivation of nitroglycerin by ascorbate

artículo científico publicado en 2007

Bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases

artículo científico publicado en 2008

Bioactivation of nitroglycerin by the East Asian variant of aldehyde dehydrogenase-2

Bioactivation of nitroglycerin by the East Asian variant of aldehyde dehydrogenase-2.

artículo científico publicado en 2009

Bioactivation of pentaerythrityl tetranitrate by mitochondrial aldehyde dehydrogenase.

artículo científico publicado en 2010

Bioactivation of pentaerythrityl tetranitrate by mitochondrial aldehyde dehydrogenase.

artículo científico publicado en 2009

Cellular Distribution and Function of Soluble Guanylyl Cyclase in Rat Kidney and Liver ⬇️

artículo científico publicado el 1 de noviembre de 2001

Characterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1.

artículo científico publicado en 2009

Comparative analysis of PDE10A isoforms.

artículo científico publicado en 2011

Contribution of aldehyde dehydrogenase to mitochondrial bioactivation of nitroglycerin: evidence for the activation of purified soluble guanylate cyclase through direct formation of nitric oxide.

artículo científico publicado en 2005

Crystal structure of the GAF-B domain from human phosphodiesterase 5

artículo científico publicado en 2011

Crystal structure of the guanylyl cyclase Cya2

artículo científico publicado en 2008

Cyclic GMP in Vascular Relaxation: Export Is of Similar Importance as Degradation

artículo científico publicado en 2015

Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases

scientific journal article

Design of fluorescence resonance energy transfer (FRET)-based cGMP indicators: a systematic approach

artículo científico publicado en 2007

Dimerization of nitric oxide-sensitive guanylyl cyclase requires the alpha 1 N terminus.

artículo científico publicado en 2005

Dissociation of Nitric Oxide from Soluble Guanylate Cyclase ⬇️

artículo científico publicado el 9 de octubre de 1997

Dual acylation of PDE2A splice variant 3: targeting to synaptic membranes

scientific journal article

Effects of flavoring compounds used in electronic cigarette refill liquids on endothelial and vascular function

scientific article published on 09 September 2019

Effects of nitroglycerin/L-cysteine on soluble guanylate cyclase: evidence for an activation/inactivation equilibrium controlled by nitric oxide binding and haem oxidation.

artículo científico publicado en 2005

Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin.

artículo científico publicado en 2016

Functional properties of a naturally occurring isoform of soluble guanylyl cyclase ⬇️

artículo científico publicado el 1 de octubre de 1998

GAF domain-induced activation of phosphodiesterases 2 and 5

Guanylyl cyclase: NO hits its target.

artículo científico publicado en 2004

In striatum phosphodiesterase 10A is part of a synaptic signalling complex.

artículo científico publicado en 2013

In vivo reconstitution of the negative feedback in nitric oxide/cGMP signaling: role of phosphodiesterase type 5 phosphorylation

artículo científico publicado en 2004

Inactivation of soluble guanylate cyclase by stoichiometric S-nitrosation

artículo científico publicado en 2008

Inhibition of deactivation of NO-sensitive guanylyl cyclase accounts for the sensitizing effect of YC-1.

artículo científico publicado en 2002

Inhibition of phosphodiesterase type 5 by the activator of nitric oxide-sensitive guanylyl cyclase BAY 41-2272.

artículo científico publicado en 2004

Irreversible activation and stabilization of soluble guanylate cyclase by the protoporphyrin IX mimetic cinaciguat.

artículo científico publicado en 2017

Isoforms of NO-sensitive guanylyl cyclase

artículo científico publicado en 2002

Major occurrence of the new alpha2beta1 isoform of NO-sensitive guanylyl cyclase in brain

artículo científico publicado en 2003

Measurement of cGMP-generating and -degrading activities and cGMP levels in cells and tissues: Focus on FRET-based cGMP indicators

artículo científico publicado en 2018

Mechanisms underlying activation of soluble guanylate cyclase by the nitroxyl donor Angeli's salt

artículo científico publicado en 2009

Mind the gap (junction): cGMP induced by nitric oxide in cardiac myocytes originates from cardiac fibroblasts

scientific article published on 27 December 2019

Mitochondrial nitrite reduction coupled to soluble guanylate cyclase activation: lack of evidence for a role in the bioactivation of nitroglycerin.

artículo científico publicado en 2008

Modulation of nitric oxide-stimulated soluble guanylyl cyclase activity by cytoskeleton-associated proteins in vascular smooth muscle

scientific article published on 10 August 2018

NO activation of guanylyl cyclase

artículo científico publicado en 2004

NO-dependent cGMP signalling in neurons and astrocytes

artículo científico publicado en 2015

NO/cGMP: The Past, the Present, and the Future ⬇️

artículo científico publicado el 1 de enero de 2013

Nitric oxide-sensitive guanylyl cyclase: structure and regulation

artículo científico publicado en 2004

Phosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in Striatum

artículo científico publicado en 2015

Phosphodiesterase 3A and Arterial Hypertension

artículo científico publicado en 2020

Physiological Functions of NO-Sensitive Guanylyl Cyclase Isoforms

artículo científico publicado en 2016

Potent inhibition of aldehyde dehydrogenase-2 by diphenyleneiodonium: focus on nitroglycerin bioactivation.

artículo científico publicado en 2013

Potent inhibition of nitroglycerin bioactivation by diphenyleneiodonium (DIP).

artículo científico publicado en 2013

Purification and characterization of NO-sensitive guanylyl cyclase

artículo científico publicado en 2005

Role of the general base Glu-268 in nitroglycerin bioactivation and superoxide formation by aldehyde dehydrogenase-2.

artículo científico publicado en 2009

Role of the general base Glu268 in nitroglycerin bioactivation and mechanism-based superoxide formation by aldehyde dehydrogenase-2.

artículo científico publicado en 2009

Scavenging of nitric oxide by hemoglobin in the tunica media of porcine coronary arteries.

artículo científico publicado en 2016

Sildenafil Does Not Prevent Heart Hypertrophy and Fibrosis Induced by Cardiomyocyte Angiotensin II Type 1 Receptor Signaling

artículo científico publicado en 2015

Site-directed mutagenesis of aldehyde dehydrogenase-2 suggests three distinct pathways of nitroglycerin biotransformation

artículo científico publicado en 2011

Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system

artículo científico publicado en 2006

Structural and mechanistic insights into cGMP signaling

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes

The commonly used cGMP-dependent protein kinase type I (cGKI) inhibitor Rp-8-Br-PET-cGMPS can activate cGKI in vitro and in intact cells

artículo científico publicado en 2008

The enhanced NO-induced cGMP response induced by long-term L-NAME treatment is not due to enhanced expression of NO-sensitive guanylyl cyclase

artículo científico publicado en 2003

The neuronal PDE2A3 splice variant is targeted to membranes via dual acylation

Transgenic mice for cGMP imaging

artículo científico publicado en 2013

Visualization of cGMP with cGi biosensors.

artículo científico publicado en 2013

cGMP Imaging in Brain Slices Reveals Brain Region-Specific Activity of NO-Sensitive Guanylyl Cyclases (NO-GCs) and NO-GC Stimulators

scholarly article by Stefanie Peters published in August 2018

cGMP signals in smooth muscle cells and cardiac myocytes.

artículo científico publicado en 2011

Lista de obras de

A phosphodiesterase 2A isoform localized to mitochondria regulates respiration

AMPA Induces NO-Dependent cGMP Signals in Hippocampal and Cortical Neurons via L-Type Voltage-Gated Calcium Channels

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017

Activation of PDE10 and PDE11 Phosphodiesterases ⬇️

Activation of PDE10 and PDE11.

Activation of PDE2 and PDE5 by specific GAF ligands: delayed activation of PDE5.

Analysis of cGMP signalling with transgenic mice expressing FRET-based cGMP sensors

Angiotensin II-Induced Hypertension Is Attenuated by Reduction of Sympathetic Output in NO-Sensitive Guanylyl Cyclase 1 Knockout Mice

Bioactivation of nitroglycerin by ascorbate

Bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases

Bioactivation of nitroglycerin by the East Asian variant of aldehyde dehydrogenase-2

Bioactivation of nitroglycerin by the East Asian variant of aldehyde dehydrogenase-2.

Bioactivation of pentaerythrityl tetranitrate by mitochondrial aldehyde dehydrogenase.

Bioactivation of pentaerythrityl tetranitrate by mitochondrial aldehyde dehydrogenase.

Cellular Distribution and Function of Soluble Guanylyl Cyclase in Rat Kidney and Liver ⬇️

Characterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1.

Comparative analysis of PDE10A isoforms.

Contribution of aldehyde dehydrogenase to mitochondrial bioactivation of nitroglycerin: evidence for the activation of purified soluble guanylate cyclase through direct formation of nitric oxide.

Crystal structure of the GAF-B domain from human phosphodiesterase 5

Crystal structure of the guanylyl cyclase Cya2

Cyclic GMP in Vascular Relaxation: Export Is of Similar Importance as Degradation

Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases

Design of fluorescence resonance energy transfer (FRET)-based cGMP indicators: a systematic approach

Dimerization of nitric oxide-sensitive guanylyl cyclase requires the alpha 1 N terminus.

Dissociation of Nitric Oxide from Soluble Guanylate Cyclase ⬇️

Dual acylation of PDE2A splice variant 3: targeting to synaptic membranes

Effects of flavoring compounds used in electronic cigarette refill liquids on endothelial and vascular function

Effects of nitroglycerin/L-cysteine on soluble guanylate cyclase: evidence for an activation/inactivation equilibrium controlled by nitric oxide binding and haem oxidation.

Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin.

Functional properties of a naturally occurring isoform of soluble guanylyl cyclase ⬇️

GAF domain-induced activation of phosphodiesterases 2 and 5

Guanylyl cyclase: NO hits its target.

In striatum phosphodiesterase 10A is part of a synaptic signalling complex.

In vivo reconstitution of the negative feedback in nitric oxide/cGMP signaling: role of phosphodiesterase type 5 phosphorylation

Inactivation of soluble guanylate cyclase by stoichiometric S-nitrosation

Inhibition of deactivation of NO-sensitive guanylyl cyclase accounts for the sensitizing effect of YC-1.

Inhibition of phosphodiesterase type 5 by the activator of nitric oxide-sensitive guanylyl cyclase BAY 41-2272.

Irreversible activation and stabilization of soluble guanylate cyclase by the protoporphyrin IX mimetic cinaciguat.

Isoforms of NO-sensitive guanylyl cyclase

Major occurrence of the new alpha2beta1 isoform of NO-sensitive guanylyl cyclase in brain

Measurement of cGMP-generating and -degrading activities and cGMP levels in cells and tissues: Focus on FRET-based cGMP indicators

Mechanisms underlying activation of soluble guanylate cyclase by the nitroxyl donor Angeli's salt

Mind the gap (junction): cGMP induced by nitric oxide in cardiac myocytes originates from cardiac fibroblasts

Mitochondrial nitrite reduction coupled to soluble guanylate cyclase activation: lack of evidence for a role in the bioactivation of nitroglycerin.

Modulation of nitric oxide-stimulated soluble guanylyl cyclase activity by cytoskeleton-associated proteins in vascular smooth muscle

NO activation of guanylyl cyclase

NO-dependent cGMP signalling in neurons and astrocytes

NO/cGMP: The Past, the Present, and the Future ⬇️

Nitric oxide-sensitive guanylyl cyclase: structure and regulation

Phosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in Striatum

Phosphodiesterase 3A and Arterial Hypertension

Physiological Functions of NO-Sensitive Guanylyl Cyclase Isoforms

Potent inhibition of aldehyde dehydrogenase-2 by diphenyleneiodonium: focus on nitroglycerin bioactivation.

Potent inhibition of nitroglycerin bioactivation by diphenyleneiodonium (DIP).

Purification and characterization of NO-sensitive guanylyl cyclase

Role of the general base Glu-268 in nitroglycerin bioactivation and superoxide formation by aldehyde dehydrogenase-2.

Role of the general base Glu268 in nitroglycerin bioactivation and mechanism-based superoxide formation by aldehyde dehydrogenase-2.

Scavenging of nitric oxide by hemoglobin in the tunica media of porcine coronary arteries.

Sildenafil Does Not Prevent Heart Hypertrophy and Fibrosis Induced by Cardiomyocyte Angiotensin II Type 1 Receptor Signaling

Site-directed mutagenesis of aldehyde dehydrogenase-2 suggests three distinct pathways of nitroglycerin biotransformation

Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system

Structural and mechanistic insights into cGMP signaling

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes

The commonly used cGMP-dependent protein kinase type I (cGKI) inhibitor Rp-8-Br-PET-cGMPS can activate cGKI in vitro and in intact cells

The enhanced NO-induced cGMP response induced by long-term L-NAME treatment is not due to enhanced expression of NO-sensitive guanylyl cyclase

The neuronal PDE2A3 splice variant is targeted to membranes via dual acylation

Transgenic mice for cGMP imaging

Visualization of cGMP with cGi biosensors.

cGMP Imaging in Brain Slices Reveals Brain Region-Specific Activity of NO-Sensitive Guanylyl Cyclases (NO-GCs) and NO-GC Stimulators

cGMP signals in smooth muscle cells and cardiac myocytes.