Lista de obras -

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes

artículo científico publicado en 2013

An HIV-1 Nef genotype that diminishes immune control mediated by protective human leucocyte antigen alleles

artículo científico publicado en 2020

Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection

scientific article published on 25 March 2020

Consequences of HLA-associated mutations in HIV-1 subtype C Nef on HLA-I downregulation ability

scientific article published on 16 January 2020

Correction for Ojwach et al., "Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection"

article

Dual HLA B42 and B81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants

artículo científico publicado en 2018

Genetic determinants of Nef-mediated CD4 and HLA class I down-regulation differences between HIV-1 subtypes B and C.

artículo científico publicado en 2015

HIV-1 evades a gag mutation that abrogates KIR binding and disinhibits NK cells in infected individuals with KIR2DL2+/HLA-C*03: 04+ genotype

artículo científico publicado en 2020

HIV-1 vaccine immunogen design strategies

artículo científico publicado en 2015

High frequency of transmitted HIV-1 Gag HLA class I-driven immune escape variants but minimal immune selection over the first year of clade C infection

artículo científico publicado en 2015

Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence

artículo científico publicado en 2014

Intersubtype differences in the effect of a rare p24 gag mutation on HIV-1 replicative fitness

artículo científico publicado en 2012

Limited Sequence Variation and Similar Phenotypic Characteristics of HIV-1 Subtype C Gag Variants Derived From the Reservoir and Pre-Therapy Plasma

artículo científico publicado en 2022

Modelling and in vitro testing of the HIV-1 Nef fitness landscape

artículo científico publicado en 2019

Mother-to-Child HIV Transmission Bottleneck Selects for Consensus Virus with Lower Gag-Protease-Driven Replication Capacity

artículo científico publicado en 2017

Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure

artículo científico publicado en 2014

Nef-mediated inhibition of NFAT following TCR stimulation differs between HIV-1 subtypes

scientific article published on 21 February 2019

No evidence for selection of HIV-1 with enhanced gag-protease or Nef function among breakthrough infections in the CAPRISA 004 tenofovir microbicide trial

artículo científico publicado en 2013

Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection

artículo científico publicado en 2018

Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals

artículo científico publicado en 2017

Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa

artículo científico publicado en 2015

Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression

artículo científico publicado en 2017

Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa

artículo científico publicado en 2021

The fitness landscape of HIV-1 gag: advanced modeling approaches and validation of model predictions by in vitro testing

artículo científico publicado en 2014

The latest science from the IAS Towards an HIV Cure Symposium: 16-17 July 2016, Durban, South Africa

artículo científico publicado en 2016

Translating HIV sequences into quantitative fitness landscapes predicts viral vulnerabilities for rational immunogen design

artículo científico publicado en 2013

Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5

artículo científico publicado en 2020

Vulnerable targets in HIV-1 Pol for attenuation-based vaccine design

artículo científico publicado en 2020

Lista de obras de

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes

An HIV-1 Nef genotype that diminishes immune control mediated by protective human leucocyte antigen alleles

Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection

Consequences of HLA-associated mutations in HIV-1 subtype C Nef on HLA-I downregulation ability

Correction for Ojwach et al., "Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection"

Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants

Genetic determinants of Nef-mediated CD4 and HLA class I down-regulation differences between HIV-1 subtypes B and C.

HIV-1 evades a gag mutation that abrogates KIR binding and disinhibits NK cells in infected individuals with KIR2DL2+/HLA-C*03: 04+ genotype

HIV-1 vaccine immunogen design strategies

High frequency of transmitted HIV-1 Gag HLA class I-driven immune escape variants but minimal immune selection over the first year of clade C infection

Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence

Intersubtype differences in the effect of a rare p24 gag mutation on HIV-1 replicative fitness

Limited Sequence Variation and Similar Phenotypic Characteristics of HIV-1 Subtype C Gag Variants Derived From the Reservoir and Pre-Therapy Plasma

Modelling and in vitro testing of the HIV-1 Nef fitness landscape

Mother-to-Child HIV Transmission Bottleneck Selects for Consensus Virus with Lower Gag-Protease-Driven Replication Capacity

Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure

Nef-mediated inhibition of NFAT following TCR stimulation differs between HIV-1 subtypes

No evidence for selection of HIV-1 with enhanced gag-protease or Nef function among breakthrough infections in the CAPRISA 004 tenofovir microbicide trial

Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection

Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals

Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa

Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression

Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa

The fitness landscape of HIV-1 gag: advanced modeling approaches and validation of model predictions by in vitro testing

The latest science from the IAS Towards an HIV Cure Symposium: 16-17 July 2016, Durban, South Africa

Translating HIV sequences into quantitative fitness landscapes predicts viral vulnerabilities for rational immunogen design

Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5

Vulnerable targets in HIV-1 Pol for attenuation-based vaccine design

Dual HLA B42 and B81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants