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A Combined Set of Four Serum Inflammatory Biomarkers Reliably Predicts Endoscopic Disease Activity in Inflammatory Bowel Disease

scientific article published on 05 November 2019

A combination of fecal calprotectin and human beta-defensin 2 facilitates diagnosis and monitoring of inflammatory bowel disease

artículo científico publicado en 2021

A cross-ethnic survey of CFB and SLC44A4, Indian ulcerative colitis GWAS hits, underscores their potential role in disease susceptibility

artículo científico publicado en 2016

A large variety of clinical features and concomitant disorders in celiac disease - A cohort study in the Netherlands

artículo científico publicado en 2016

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease

scientific journal article

A novel prognostic model for transplant-free survival in primary sclerosing cholangitis.

artículo científico publicado en 2017

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

artículo científico publicado en 2016

ATG16L1andIL23RAre Associated With Inflammatory Bowel Diseases but Not With Celiac Disease in The Netherlands

article

Agile patency system

scientific article published on 01 March 2009

Alkaline phosphatase at diagnosis of primary sclerosing cholangitis and 1 year later: evaluation of prognostic value

artículo científico publicado en 2016

Analysis of 1135 gut metagenomes identifies sex-specific resistome profiles

artículo científico publicado en 2018

Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease

artículo científico publicado en 2010

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

artículo científico publicado en 2016

Anti-inflammatory Gut Microbial Pathways Are Decreased During Crohn's Disease Exacerbations

artículo científico publicado en 2019

Are pancreatic autoantibodies associated with azathioprine-induced pancreatitis in Crohn's disease?

artículo científico publicado en 2008

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

artículo científico publicado en 2015

Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes

artículo científico publicado en 2015

Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies

artículo científico publicado en 2013

Association of FcgR2a, but not FcgR3a, with inflammatory bowel diseases across three Caucasian populations†

artículo científico publicado en 2010

Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease

scientific article published on 01 February 2019

Association of interleukin-1 receptor-associated kinase M (IRAK-M) and inflammatory bowel diseases

artículo científico publicado en 2007

Association of the protein-tyrosine phosphatase nonreceptor type substrate 1 (PTPNS1) gene with inflammatory bowel disease

artículo científico publicado en 2010

Author Correction: Gut microbiome structure and metabolic activity in inflammatory bowel disease

scientific article published on 01 May 2019

Can we reduce capsule endoscopy reading times?

artículo científico publicado en 2008

Cell Specific eQTL Analysis without Sorting Cells

artículo científico publicado en 2015

Cell specific eQTL analysis without sorting cells

Changes in gene expression caused by insect venom immunotherapy responsible for the long-term protection of insect venom-allergic patients

artículo científico publicado en 2011

Characteristics and Dysbiosis of the Gut Microbiome in Renal Transplant Recipients

artículo científico publicado en 2020

Clinical Features and HLA Association of 5-Aminosalicylate (5-ASA)-induced Nephrotoxicity in Inflammatory Bowel Disease

artículo científico publicado en 2015

Cohort profile: design and first results of the Dutch IBD Biobank: a prospective, nationwide biobank of patients with inflammatory bowel disease

artículo científico publicado en 2017

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

artículo científico publicado en 2010

Comorbidity, not patient age, is associated with impaired safety outcomes in vedolizumab- and ustekinumab-treated patients with inflammatory bowel disease-a prospective multicentre cohort study

artículo científico publicado en 2020

Completion rate of small bowel capsule endoscopy is higher after erythromycin compared to domperidone

artículo científico publicado en 2014

Complex host genetics influence the microbiome in inflammatory bowel disease

artículo científico publicado en 2014

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort

artículo científico publicado en 2009

Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer

artículo científico publicado en 2014

Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

correction of a scientific article; published on 30 May 2019

Correlation of genetic risk and messenger RNA expression in a Th17/IL23 pathway analysis in inflammatory bowel disease

artículo científico publicado en 2014

Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma

artículo científico publicado en 2022

DNA polymorphisms predict time to progression from uncomplicated to complicated Crohn's disease

artículo científico publicado en 2017

Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis

artículo científico publicado en 2013

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

artículo científico publicado en 2013

Diagnostic yield of small bowel capsule endoscopy depends on the small bowel transit time ⬇️

artículo científico publicado el 7 de abril de 2012

Differences in genetic background between active smokers, passive smokers, and non-smokers with Crohn's disease

scientific article published on December 2009

Differential association of two PTPN22 coding variants with Crohn's disease and ulcerative colitis

artículo científico publicado en 2011

Distinctive inflammatory bowel disease phenotype in primary sclerosing cholangitis

artículo científico publicado en 2015

Diversity and Ecology of Caudoviricetes Phages with Genome Terminal Repeats in Fecal Metagenomes from Four Dutch Cohorts

artículo científico publicado en 2022

Diverticular disease: picking pockets and population biobanks

scientific article published on 02 March 2019

Donor genetic variants as risk factors for thrombosis after liver transplantation: A genome‐wide association study

artículo científico publicado en 2021

Donor tobacco smoking is associated with postoperative thrombosis after primary liver transplantation

artículo científico publicado en 2020

Down the line from genome-wide association studies in inflammatory bowel disease: the resulting clinical benefits and the outlook for the future

artículo científico

Drug Repositioning in Inflammatory Bowel Disease Based on Genetic Information

artículo científico publicado en 2016

Effects of active and passive smoking on disease course of Crohn's disease and ulcerative colitis

artículo científico publicado en 2009

Effects of magnesium citrate, magnesium oxide and magnesium sulfate supplementation on arterial stiffness in healthy overweight individuals: a study protocol for a randomized controlled trial.

artículo científico publicado en 2019

Endoscopic assessment of primary sclerosing cholangitis.

artículo científico publicado en 2015

Endoscopic corticosteroid injections do not reduce dysphagia after endoscopic dilation therapy in patients with benign esophagogastric anastomotic strictures

artículo científico publicado en 2013

Environmental factors associated with biological use and surgery in Inflammatory Bowel Disease

artículo científico publicado en 2020

Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

artículo científico publicado en 2016

Erratum: Corrigendum: Genetic Analysis in A Dutch Study Sample Identifies More Ulcerative Colitis Susceptibility Loci and Shows Their Additive Role in Disease Risk

scholarly article published in The American Journal of Gastroenterology

Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scholarly article published in Nature Genetics

Erratum: Corrigendum: Multiple common variants for celiac disease influencing immune gene expression

article

Erratum: Genome-wide association identifies multiple ulcerative colitis susceptibility loci

scholarly article published in Nature Genetics

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

artículo científico publicado en 2012

Extraintestinal manifestations and complications in inflammatory bowel disease: from shared genetics to shared biological pathways

artículo científico

Farnesoid X receptor (FXR) activation and FXR genetic variation in inflammatory bowel disease

artículo científico publicado en 2011

Fine-mapping inflammatory bowel disease loci to single-variant resolution

artículo científico publicado en 2017

Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk

artículo científico publicado en 2009

Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP.

artículo científico publicado en 2008

Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease

artículo científico publicado en 2013

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis

artículo científico publicado en 2017

Genetic association analysis of the functional c.714T>G polymorphism and mucosal expression of dectin-1 in inflammatory bowel disease

artículo científico publicado en 2009

Genetic effects on the commensal microbiota in inflammatory bowel disease patients

artículo científico publicado en 2019

Genetic polymorphism inATG16L1gene influences the response to adalimumab in Crohn's disease patients

article

Genetic susceptibility has a more important role in pediatric-onset Crohn's disease than in adult-onset Crohn's disease

scientific article published on 01 September 2007

Genome-wide association analysis in primary sclerosing cholangitis

artículo científico publicado en 2009

Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4

scientific journal article

Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

scientific journal article

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

artículo científico publicado en 2010

Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis

scientific journal article

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

artículo científico publicado en 2016

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

artículo científico publicado en 2010

Genomic and Expression Analyses Identify a Disease-Modifying Variant for Fibrostenotic Crohn's Disease.

artículo científico publicado en 2018

Gut microbial co-abundance networks show specificity in inflammatory bowel disease and obesity

artículo científico publicado en 2020

Gut microbial species and metabolic pathways associated with response to treatment with immune checkpoint inhibitors in metastatic melanoma

artículo científico publicado en 2020

Gut microbiome structure and metabolic activity in inflammatory bowel disease

artículo científico publicado en 2018

Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome

scientific article published on 01 December 2018

Gut microbiota in inflammatory bowel diseases: moving from basic science to clinical applications

scientific article published on 28 August 2020

HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.

artículo científico publicado en 2014

HNF4α and CDH1 are associated with ulcerative colitis in a Dutch cohort

scholarly article by Suzanne van Sommeren et al published August 2011 in Inflammatory Bowel Diseases

HSPA6 is an ulcerative colitis susceptibility factor that is induced by cigarette smoke and protects intestinal epithelial cells by stabilizing anti-apoptotic Bcl-XL.

artículo científico publicado en 2016

Habitual dietary intake of IBD patients differs from population controls: a case-control study

scientific article published on 24 April 2020

Haplotype-based analysis of ulcerative colitis risk loci identifies both IL2 and IL21 as susceptibility genes in Han Chinese

artículo científico publicado en 2011

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

artículo científico publicado en 2012

IBD is associated with an increase in carcinoma in PSC irrespective of the presence of dominant bile duct stenosis ⬇️

artículo científico publicado el 23 de abril de 2012

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes

artículo científico publicado en 2018

Identification of Clinical and Genetic Parameters Associated with Hidradenitis Suppurativa in Inflammatory Bowel Disease

artículo científico publicado en 2015

Identification of environmental risk factors associated with the development of Inflammatory Bowel Disease

artículo científico publicado en 2020

Immune-mediated diseases in primary sclerosing cholangitis

artículo científico publicado en 2011

Impact of commonly used drugs on the composition and metabolic function of the gut microbiota

artículo científico publicado en 2020

Inflammatory Bowel Disease

Inflammatory bowel disease and celiac disease: overlaps in the pathology and genetics, and their potential drug targets

artículo científico publicado en 2009

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

artículo científico publicado en 2015

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

artículo científico publicado en 2018

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

preprint published 25 September 2016

Interaction between drugs and the gut microbiome

artículo científico publicado en 2020

Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease

artículo científico publicado en 2016

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

artículo científico publicado en 2016

Is there a role for Crohn's disease-associated autophagy genes ATG16L1 and IRGM in formation of granulomas?

artículo científico publicado en 2010

Isotype specific antibody responses to Mycobacterium Avium subspecies Paratuberculosis antigens are associated with the use of biological therapy in Inflammatory Bowel Disease

artículo científico publicado en 2020

Latent cytomegalovirus infection does not influence long-term disease outcomes in inflammatory bowel disease, but is associated with later onset of disease

artículo científico publicado en 2020

Limited diagnostic accuracy and clinical impact of single-operator peroral cholangioscopy for indeterminate biliary strictures

scientific article published on 13 December 2019

Limited evidence for parent-of-origin effects in inflammatory bowel disease associated loci

artículo científico publicado en 2012

Low levels of vitamin D are associated with multimorbidity: results from the LifeLines Cohort Study

artículo científico publicado en 2015

Lower rate of major bile duct injury and increased intraoperative management of common bile duct stones after implementation of routine intraoperative cholangiography

artículo científico publicado en 2011

MMP‐2 is a disease‐modifying gene in primary sclerosing cholangitis ⬇️

artículo científico publicado el 28 de junio de 2013

MOLGENIS research: advanced bioinformatics data software for non-bioinformaticians

scientific article published on 01 March 2019

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Multi-locus genetic risk score predicts risk for Crohn's disease in Slovenian population

artículo científico publicado en 2016

Multiomics Analyses to Deliver the Most Effective Treatment to Every Patient With Inflammatory Bowel Disease

artículo científico publicado en 2018

Multiple common variants for celiac disease influencing immune gene expression

artículo científico publicado en 2010

Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis

artículo científico publicado en 2010

Non-classical clinical presentation at diagnosis by male celiac disease patients of older age

artículo científico publicado en 2020

Non-small-bowel abnormalities identified during small bowel capsule endoscopy

artículo científico publicado en 2014

Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis

artículo científico publicado en 2017

Performance of the Montreal classification for inflammatory bowel diseases

artículo científico publicado en 2014

Pharmacomicrobiomics: a novel route towards personalized medicine?

artículo científico publicado en 2018

Pooled Resequencing of 122 Ulcerative Colitis Genes in a Large Dutch Cohort Suggests Population-Specific Associations of Rare Variants in MUC2

artículo científico publicado en 2016

Population-based epidemiology, malignancy risk, and outcome of primary sclerosing cholangitis ⬇️

artículo científico publicado el 17 de octubre de 2013

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

artículo científico publicado en 2016

Predicted efficacy of a pharmacogenetic passport for inflammatory bowel disease

artículo científico publicado en 2020

Prevalence of- and risk factors for work disability in Dutch patients with inflammatory bowel disease

artículo científico publicado en 2017

Procedure-related, false-positive cytology results during EUS-guided FNA in patients with esophageal cancer

artículo científico publicado en 2010

Proton pump inhibitors affect the gut microbiome

artículo científico publicado en 2015

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

artículo científico publicado en 2011

Recipient’s Genetic R702W NOD2 Variant Is Associated with an Increased Risk of Bacterial Infections after Orthotopic Liver Transplantation ⬇️

artículo científico publicado el 19 de agosto de 2013

Reduced salivary secretion contributes more to changes in the oral microbiome of patients with primary Sjögren's syndrome than underlying disease

artículo científico publicado en 2018

Riboflavin supplementation in patients with Crohn's disease (RISE-UP study)

scientific article published on 24 December 2019

Risk factors for incomplete small-bowel capsule endoscopy

artículo científico publicado en 2008

Runt-related transcription factor 3 is associated with ulcerative colitis and shows epistasis with solute carrier family 22, members 4 and 5.

artículo científico publicado en 2008

SLC39A8 missense variant is associated with Crohn's disease but does not have a major impact on gut microbiome composition in healthy subjects

scientific article published in PLoS ONE

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

artículo científico publicado en 2008

Sex-Related Differences in Patients With Inflammatory Bowel Disease: Results of 2 Prospective Cohort Studies

artículo científico publicado en 2018

Shared gut, but distinct oral microbiota composition in primary Sjögren's syndrome and systemic lupus erythematosus

article

Shifting Paradigms: What Is the True Prevalence and Clinical Course of Primary Sclerosing Cholangitis?

artículo científico publicado en 2016

Single-cell RNA Sequencing of Blood and Ileal T cells From Patients With Crohn's Disease Reveals Tissue-specific Characteristics and Drug Targets

artículo científico publicado en 2018

Suppression of p21Rac signaling and increased innate immunity mediate remission in Crohn's disease

artículo científico publicado en 2014

TNFα-antagonist use and mucosal inflammation are associated with increased intestinal expression of SARS-CoV-2 host protease TMPRSS2 in patients with inflammatory bowel disease

scientific article published on 15 June 2020

The ATG16L1-T300A allele impairs clearance of pathosymbionts in the inflamed ileal mucosa of Crohn's disease patients

artículo científico publicado en 2014

The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids

artículo científico publicado en 2015

The effect of host genetics on the gut microbiome

artículo científico

The efficacy of home telemonitoring versus conventional follow-up: a randomised controlled trial among teenagers with inflammatory bowel disease.

artículo científico publicado en 2017

The genetic background of inflammatory bowel disease: from correlation to causality.

artículo científico publicado en 2016

The genetic basis of inflammatory bowel disease unravelled by genetic association studies

artículo científico publicado en 2009

The influence of proton pump inhibitors and other commonly used medication on the gut microbiota.

artículo científico publicado en 2017

The quest for genetic risk factors for Crohn's disease in the post-GWAS era

artículo científico publicado en 2011

The role of the microbiome for human health: from basic science to clinical applications

artículo científico publicado en 2018

Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9

artículo científico publicado en 2011

Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes

artículo científico publicado en 2020

Tofacitinib for ulcerative colitis: results of the prospective Dutch Initiative on Crohn and Colitis (ICC) registry

scientific article published on 01 April 2020

Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

artículo científico publicado en 2011

Treatment of complex biliary stones by cholangioscopy laser lithotripsy in 10 patients

artículo científico publicado el 1 de enero de 2010

Understanding human gut diseases at single-cell resolution

artículo científico publicado en 2020

Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression

artículo científico publicado en 2012

Using genetic information for the identification, classification and treatment of Crohn’s disease: are we there yet?

Whole exome sequencing analyses reveal gene-microbiota interactions in the context of IBD

artículo científico publicado en 2020

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