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A clean fuel cookstove is associated with improved lung function: Effect modification by age and secondhand tobacco smoke exposure

A critical role for ABC transporters in persistent lung inflammation in the development of emphysema after smoke exposure

scientific article published on 15 June 2018

A role for collagenase (Matrix metalloproteinase-1) in pulmonary emphysema

scientific article published on 01 May 2000

Absence of gelatinase (MMP-9) or collagenase (MMP-13) attenuates adriamycin-induced albuminuria and glomerulosclerosis

artículo científico publicado en 2010

Achieving women's equity in academic medicine: challenging the standards

scientific article published on 01 February 2019

Activation of an embryonic gene product in pulmonary emphysema : identification of the secreted frizzled-related protein

artículo científico publicado en 2000

Activation of the MMP-1 promoter by cigarette smoke in human small airway epithelial cells requires ERK MAP kinase signaling: differential response of the 1G and 2G promoter sequences.

artículo científico publicado en 2006

Activation of the TLR4 signaling pathway and abnormal cholesterol efflux lead to emphysema in ApoE-deficient mice.

artículo científico publicado en 2012

Altered lymphocyte trafficking and diminished airway reactivity in transgenic mice expressing human MMP-9 in a mouse model of asthma

artículo científico publicado en 2009

ApoE knockout mice expressing human matrix metalloproteinase-1 in macrophages have less advanced atherosclerosis.

artículo científico publicado en 2001

Attenuation of pulmonary injury by an inhaled MMP inhibitor in the endotoxin lung injury model

scientific article published on 07 October 2020

Biased Generation and In Situ Activation of Lung Tissue-Resident Memory CD4 T Cells in the Pathogenesis of Allergic Asthma

artículo científico publicado en 2018

Bioactive Depsides and Anthocyanins from Jaboticaba (Myrciariacauliflora)

artículo científico publicado en 2006

Blockade of receptor for advanced glycation end product attenuates pulmonary reperfusion injury in mice

artículo científico publicado en 2008

Bone growth retardation in mouse embryos expressing human collagenase 1.

artículo científico publicado en 2007

CDK14 expression is down-regulated by cigarette smoke in vivo and in vitro

artículo científico publicado en 2015

Cathepsin G degradation of phospholipid transfer protein (PLTP) augments pulmonary inflammation.

artículo científico publicado en 2014

Cigarette smoke components induce matrix metalloproteinase-1 in aortic endothelial cells through inhibition of mTOR signaling

artículo científico publicado en 2011

Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema

artículo científico publicado en 1992

Collagenolytic matrix metalloproteinases in chronic obstructive lung disease and cancer

artículo científico publicado en 2015

Decreased elastin in vessel walls puts the pressure on

artículo científico publicado el 1 de noviembre de 2003

Deficiency of matrix metalloproteinase-13 increases inflammation after acute lung injury

artículo científico publicado en 2010

Detection of alpha-1 antitrypsin deficiency: the past, present and future

artículo científico publicado en 2020

Differential expression of WNTs and FRPs in the synovium of rheumatoid arthritis and osteoarthritis

artículo científico publicado en 2006

Differential gene expression of sFRP-1 and apoptosis in pulmonary emphysema

artículo científico publicado en 2002

Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases

artículo científico publicado en 2012

Effectiveness-based guidelines for the prevention of cardiovascular disease in women--2011 update: a guideline from the American Heart Association

artículo científico publicado en 2011

Effectiveness-based guidelines for the prevention of cardiovascular disease in women--2011 update: a guideline from the american heart association.

artículo científico publicado en 2011

Emerging role of MAP kinase pathways as therapeutic targets in COPD.

artículo científico publicado en 2006

Emphysematous changes are caused by degradation of type III collagen in transgenic mice expressing MMP-1.

artículo científico publicado en 2003

Eosinophil and T cell markers predict functional decline in COPD patients

artículo científico publicado en 2009

Episodic Aspiration with Oral Commensals Induces a MyD88-dependent, Pulmonary Th17 Response that Mitigates Susceptibility to Streptococcus pneumoniae

scientific article published on 09 November 2020

Expression of matrix metalloproteinase-1 in alveolar macrophages, type II pneumocytes, and airways in smokers: relationship to lung function and emphysema

artículo científico publicado en 2014

Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke

artículo científico publicado en 2004

FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death

artículo científico publicado en 2003

Feasibility of retinoids for the treatment of emphysema study.

artículo científico publicado en 2006

Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study

artículo científico publicado en 2012

Functional expression of the GABAB receptor in human airway smooth muscle

artículo científico publicado en 2006

Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure.

artículo científico publicado en 2016

HMGA2 is a driver of tumor metastasis.

artículo científico publicado en 2013

High Mobility Group AT-Hook 2 (HMGA2) Oncogenicity in Mesenchymal and Epithelial Neoplasia

scientific article published on 29 April 2020

Hmga2 regulation of tooth formation and association with Sox2 and Nanog expression

artículo científico publicado en 2019

Host-derived MMP-13 exhibits a protective role in lung metastasis of melanoma cells by local endostatin production.

artículo científico publicado en 2011

Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema

artículo científico publicado en 2001

Hyperpolarized (3)He diffusion MRI and histology of secreted frizzled related protein-1 (SFRP1) deficient lungs in a Murine model.

artículo científico publicado en 2014

Identification of a cigarette smoke-responsive region in the distal MMP-1 promoter

artículo científico publicado en 2008

Identification of the benign mesenchymal tumor gene HMGA2 in lymphangiomyomatosis

artículo científico publicado en 2007

Immune Modulation of the T Cell Response in Asthma through Wnt10b

artículo científico publicado en 2015

Impaired bone fracture healing in matrix metalloproteinase-13 deficient mice

scientific article published on 19 January 2007

Increased matrix metalloproteinase (MMPs) levels do not predict disease severity or progression in emphysema

artículo científico publicado en 2013

Increased medial degradation with pseudo-aneurysm formation in apolipoprotein E-knockout mice deficient in tissue inhibitor of metalloproteinases-1

scientific article published on 01 January 2003

Induction of the unfolded protein response by cigarette smoke is primarily an activating transcription factor 4-C/EBP homologous protein mediated process

artículo científico publicado el 2 de junio de 2011

Jaboticabin and Related Polyphenols from Jaboticaba ( Myrciaria cauliflora) with Anti-inflammatory Activity for Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2019

Joint diseases and matrix metalloproteinases: a role for MMP-13.

artículo científico publicado en 2008

Leaky ryanodine receptors in β-sarcoglycan deficient mice: a potential common defect in muscular dystrophy.

artículo científico publicado en 2012

Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis

scientific article published on 01 August 2006

Loss of secreted frizzled-related protein-1 leads to deterioration of cardiac function in mice and plays a role in human cardiomyopathy.

artículo científico publicado en 2015

Lymphatic impairment leads to pulmonary tertiary lymphoid organ formation and alveolar damage

artículo científico publicado en 2019

MMP-1 drives immunopathology in human tuberculosis and transgenic mice.

artículo científico publicado en 2011

MMP-13 plays a role in keratinocyte migration, angiogenesis, and contraction in mouse skin wound healing.

artículo científico publicado en 2009

Macrophage-specific expression of human collagenase (MMP-1) in transgenic mice

artículo científico publicado en 1999

Maintenance of the bronchial alveolar stem cells in an undifferentiated state by secreted frizzled-related protein 1.

artículo científico publicado en 2014

Maternal smoke exposure decreases mesenchymal proliferation and modulates Rho-GTPase-dependent actin cytoskeletal signaling in fetal lungs

artículo científico publicado en 2017

Matrix metalloproteinase disruption of the extracellular matrix and cardiac dysfunction

artículo científico publicado en 2002

Matrix metalloproteinases in development and disease

artículo científico publicado en 2006

Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseases

artículo científico publicado en 2010

Mechanical unloading during left ventricular assist device support increases left ventricular collagen cross-linking and myocardial stiffness

artículo científico publicado en 2005

Mesenchymal Tumorigenesis Driven by TSC2 Haploinsufficiency Requires HMGA2 and Is Independent of mTOR Pathway Activation.

artículo científico publicado en 2016

Mice with cardiac overexpression of peroxisome proliferator-activated receptor γ have impaired repolarization and spontaneous fatal ventricular arrhythmias

artículo científico publicado en 2011

Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice

artículo científico publicado en 2016

Mmp1a and Mmp1b are not functional orthologs to human MMP1 in cigarette smoke induced lung disease

artículo científico publicado en 2014

Monitoring and staging abdominal aortic aneurysm disease with pulse wave imaging

artículo científico publicado en 2014

Nonmalignant respiratory effects of chronic arsenic exposure from drinking water among never-smokers in Bangladesh

artículo científico publicado en 2008

Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guidelines: Lymphangioleiomyomatosis Diagnosis and Management

artículo científico publicado en 2016

Overexpression of MMP9 in macrophages attenuates pulmonary fibrosis induced by bleomycin

artículo científico publicado en 2007

Parenchymal Airspace Profiling: Sensitive Quantification and Characterization of Lung Structure Evaluating Parenchymal Destruction.

artículo científico publicado en 2016

Pivotal role of matrix metalloproteinase 13 in extracellular matrix turnover in idiopathic pulmonary fibrosis

artículo científico publicado en 2013

Platelet activation in the postoperative period after lung transplantation

artículo científico publicado en 2008

Progressive adult-onset emphysema in transgenic mice expressing human MMP-1 in the lung.

artículo científico publicado en 2003

Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol

artículo científico publicado en 2002

Protein phosphatase 2A regulates innate immune and proteolytic responses to cigarette smoke exposure in the lung

artículo científico publicado en 2012

Reduced vascular smooth muscle BK channel current underlies heart failure-induced vasoconstriction in mice.

artículo científico publicado en 2013

Reply: Parenchymal Airspace Profiling Has Its Merits and Is a Valuable Addition to Existing Methods for Lung Morphometry.

artículo científico publicado en 2017

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

artículo científico publicado en 2002

Role for cathepsin K in emphysema in smoke-exposed guinea pigs

artículo científico publicado en 2009

Second hand smoke and COPD: lessons from animal studies.

artículo científico publicado en 2013

Single-Photon Emission Computed Tomography/Computed Tomography Imaging in a Rabbit Model of Emphysema Reveals Ongoing Apoptosis In Vivo

artículo científico publicado en 2016

Single-photon emission computed tomography/computed tomography imaging of RAGE in smoking-induced lung injury.

artículo científico publicado en 2019

Spontaneous atherothrombosis and medial degradation in Apoe-/-, Npc1-/- mice

artículo científico publicado en 2007

Structural emphysema does not correlate with lung compliance: lessons from the mouse smoking model.

artículo científico publicado en 2005

Superoxide dismutase expression attenuates cigarette smoke- or elastase-generated emphysema in mice.

artículo científico publicado en 2005

TLR3 deficiency protects against collagen degradation and medial destruction in murine atherosclerotic plaques

artículo científico publicado en 2013

TLR4 protein contributes to cigarette smoke-induced matrix metalloproteinase-1 (MMP-1) expression in chronic obstructive pulmonary disease

artículo científico publicado en 2011

The Effect of Cigarette Smoke-derived Oxidants on the Inflammatory Response of the Lung

artículo científico publicado en 2006

The Epithelial Cell in Lung Health and Emphysema Pathogenesis

scientific article published on May 2006

The Extracellular Matrix Regulates Granuloma Necrosis in Tuberculosis.

artículo científico publicado en 2015

The International LAM Registry: a component of an innovative web-based clinician, researcher, and patient-driven rare disease research platform.

artículo científico

The divergent roles of secreted frizzled related protein-1 (SFRP1) in lung morphogenesis and emphysema.

artículo científico publicado en 2010

The glutathione peroxidase 1-protein tyrosine phosphatase 1B-protein phosphatase 2A axis. A key determinant of airway inflammation and alveolar destruction

artículo científico publicado en 2013

The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor

artículo científico publicado en 2003

The impact of angiotensin-converting enzyme inhibitor therapy on the extracellular collagen matrix during left ventricular assist device support in patients with end-stage heart failure

artículo científico publicado en 2007

The pharmokinetic limitations of antioxidant treatment for COPD.

artículo científico publicado en 2007

Tissue, temporal and inducible expression pattern of haptoglobin in mice

artículo científico publicado el 11 de agosto de 1997

Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis

artículo científico publicado en 2016

Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis

artículo científico publicado en 2016

Transgenic expression of matrix metalloproteinase-1 inhibits myocardial fibrosis and prevents the transition to heart failure in a pressure overload mouse model

scientific article published on 01 April 2008

Transgenic expression of matrix metalloproteinase-9 causes adult-onset emphysema in mice associated with the loss of alveolar elastin

artículo científico publicado en 2008

Transgenic expression of matrix metalloproteinase-9 modulates collagen deposition in a mouse model of atherosclerosis.

artículo científico publicado en 2008

Treatment of experimental asthma using a single small molecule with anti-inflammatory and BK channel-activating properties

artículo científico publicado en 2013

Tuberculosis immunopathology: the neglected role of extracellular matrix destruction.

artículo científico publicado en 2011

Tuberous sclerosis-associated lesions of the kidney, brain, and skin are angiogenic neoplasms

scientific article published on 01 March 2002