Lista de obras -

A SAR study of novel antiproliferative ruthenium and osmium complexes with quinoxalinone ligands in human cancer cell lines

artículo científico publicado en 2012

A novel class of bis- and tris-chelate diam(m)inebis(dicarboxylato)platinum(IV) complexes as potential anticancer prodrugs.

artículo científico publicado en 2014

Amidines derived from Pt(IV)-mediated nitrile-amino alcohol coupling and their Zn(II)-catalyzed conversion into oxazolines.

artículo científico publicado en 2003

Anticancer activity of methyl-substituted oxaliplatin analogs

artículo científico publicado en 2012

Antitumour metal compounds: more than theme and variations

artículo científico publicado en 2007

Behavior of platinum(iv) complexes in models of tumor hypoxia: cytotoxicity, compound distribution and accumulation

artículo científico publicado en 2016

Bis- and Tetrakis(carboxylato)platinum(IV) complexes with mixed axial ligands - synthesis, characterization, and cytotoxicity

artículo científico publicado en 2015

Bulky N(,N)-(di)alkylethane-1,2-diamineplatinum(II) compounds as precursors for generating unsymmetrically substituted platinum(IV) complexes.

artículo científico publicado en 2013

Cellular accumulation and DNA interaction studies of cytotoxic trans-platinum anticancer compounds

artículo científico publicado en 2012

Editorial: Bioinorganic Chemistry (ICBIC XV) ⬇️

artículo científico publicado el 1 de septiembre de 2012

Effect of metal ion complexation and chalcogen donor identity on the antiproliferative activity of 2-acetylpyridine N,N-dimethyl(chalcogen)semicarbazones.

artículo científico publicado en 2007

First example of the solid-state thermal cyclometalation of ligated benzophenone imine giving novel luminescent platinum(II) species.

artículo científico publicado en 2007

Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.

artículo científico publicado en 2009

In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands

artículo científico publicado en 2008

Influence of ascorbic acid on the activity of the investigational anticancer drug KP1019.

artículo científico publicado en 2011

Influence of extracellular pH on the cytotoxicity, cellular accumulation, and DNA interaction of novel pH-sensitive 2-aminoalcoholatoplatinum(II) complexes

artículo científico publicado en 2013

Influence of reducing agents on the cytotoxic activity of platinum(IV) complexes: induction of G2/M arrest, apoptosis and oxidative stress in A2780 and cisplatin resistant A2780cis cell lines.

artículo científico publicado en 2015

Keggin-type polyoxotungstates as mushroom tyrosinase inhibitors - A speciation study

artículo científico publicado en 2019

Kinetic and thermodynamic aspects of the regioselective addition of bifunctional hydroxylaminooxime-type HO-nucleophiles to Pt-complexed nitriles

scientific article published on 01 March 2006

LA-ICP-MS imaging in multicellular tumor spheroids - a novel tool in the preclinical development of metal-based anticancer drugs.

artículo científico publicado en 2016

Metal-based paullones as putative CDK inhibitors for antitumor chemotherapy

artículo científico publicado en 2007

Novel di- and tetracarboxylatoplatinum(IV) complexes. Synthesis, characterization, cytotoxic activity, and DNA platination.

artículo científico publicado en 2007

Novel tetracarboxylatoplatinum(IV) complexes as carboplatin prodrugs.

artículo científico publicado en 2012

Redox behavior of tumor-inhibiting ruthenium(iii) complexes and effects of physiological reductants on their binding to GMP

scientific article published on 11 January 2006

Redox-active antineoplastic ruthenium complexes with indazole: correlation of in vitro potency and reduction potential

artículo científico publicado en 2005

Resistance against novel anticancer metal compounds: differences and similarities

artículo científico publicado en 2008

Ruthenium− and Osmium−Arene Complexes of 2-Substituted Indolo[3,2-c]quinolines: Synthesis, Structure, Spectroscopic Properties, and Antiproliferative Activity ⬇️

artículo científico publicado el 27 de diciembre de 2010

Solid-phase synthesis of oxaliplatin-TAT peptide bioconjugates.

artículo científico publicado en 2012

Synthesis and characterization of novel bis(carboxylato)dichloridobis(ethylamine)platinum(IV) complexes with higher cytotoxicity than cisplatin

artículo científico publicado en 2011

Synthesis and in vitro antitumor potency of (cyclohexane-1,2-diamine)platinum(II) complexes with aminotris(methylenephosphonic acid) as bone-seeking ligand

artículo científico publicado en 2005

Synthesis, characterization, and cytotoxic activity of novel potentially pH-sensitive nonclassical platinum(II) complexes featuring 1,3-dihydroxyacetone oxime ligands.

artículo científico publicado en 2011

Synthesis, crystal structure and cytotoxicity of new oxaliplatin analogues indicating that improvement of anticancer activity is still possible.

artículo científico publicado en 2004

Synthesis, structure, spectroscopic and in vitro antitumour studies of a novel gallium(III) complex with 2-acetylpyridine (4)N-dimethylthiosemicarbazone.

artículo científico publicado en 2002

Tetracarboxylatoplatinum(IV) complexes featuring monodentate leaving groups - A rational approach toward exploiting the platinum(IV) prodrug strategy

artículo científico publicado en 2015

The first metal-based paullone derivative with high antiproliferative activity in vitro.

artículo científico publicado en 2006

The first ruthenium-based paullones: syntheses, X-ray diffraction structures, and spectroscopic and antiproliferative properties in vitro

artículo científico publicado en 2007

The role of the equatorial ligands for the redox behavior, mode of cellular accumulation and cytotoxicity of platinum(IV) prodrugs.

artículo científico publicado en 2016

Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes

artículo científico publicado en 2010

Unsymmetric mono- and dinuclear platinum(IV) complexes featuring an ethylene glycol moiety: synthesis, characterization, and biological activity

artículo científico publicado en 2012

Water-soluble cationic derivatives of indirubin, the active anticancer component from Indigo naturalis

artículo científico publicado en 2012

{(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo

artículo científico publicado en 2010

Lista de obras de

A SAR study of novel antiproliferative ruthenium and osmium complexes with quinoxalinone ligands in human cancer cell lines

A novel class of bis- and tris-chelate diam(m)inebis(dicarboxylato)platinum(IV) complexes as potential anticancer prodrugs.

Amidines derived from Pt(IV)-mediated nitrile-amino alcohol coupling and their Zn(II)-catalyzed conversion into oxazolines.

Anticancer activity of methyl-substituted oxaliplatin analogs

Antitumour metal compounds: more than theme and variations

Behavior of platinum(iv) complexes in models of tumor hypoxia: cytotoxicity, compound distribution and accumulation

Bis- and Tetrakis(carboxylato)platinum(IV) complexes with mixed axial ligands - synthesis, characterization, and cytotoxicity

Bulky N(,N)-(di)alkylethane-1,2-diamineplatinum(II) compounds as precursors for generating unsymmetrically substituted platinum(IV) complexes.

Cellular accumulation and DNA interaction studies of cytotoxic trans-platinum anticancer compounds

Editorial: Bioinorganic Chemistry (ICBIC XV) ⬇️

Effect of metal ion complexation and chalcogen donor identity on the antiproliferative activity of 2-acetylpyridine N,N-dimethyl(chalcogen)semicarbazones.

First example of the solid-state thermal cyclometalation of ligated benzophenone imine giving novel luminescent platinum(II) species.

Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.

In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands

Influence of ascorbic acid on the activity of the investigational anticancer drug KP1019.

Influence of extracellular pH on the cytotoxicity, cellular accumulation, and DNA interaction of novel pH-sensitive 2-aminoalcoholatoplatinum(II) complexes

Influence of reducing agents on the cytotoxic activity of platinum(IV) complexes: induction of G2/M arrest, apoptosis and oxidative stress in A2780 and cisplatin resistant A2780cis cell lines.

Keggin-type polyoxotungstates as mushroom tyrosinase inhibitors - A speciation study

Kinetic and thermodynamic aspects of the regioselective addition of bifunctional hydroxylaminooxime-type HO-nucleophiles to Pt-complexed nitriles

LA-ICP-MS imaging in multicellular tumor spheroids - a novel tool in the preclinical development of metal-based anticancer drugs.

Metal-based paullones as putative CDK inhibitors for antitumor chemotherapy

Novel di- and tetracarboxylatoplatinum(IV) complexes. Synthesis, characterization, cytotoxic activity, and DNA platination.

Novel tetracarboxylatoplatinum(IV) complexes as carboplatin prodrugs.

Redox behavior of tumor-inhibiting ruthenium(iii) complexes and effects of physiological reductants on their binding to GMP

Redox-active antineoplastic ruthenium complexes with indazole: correlation of in vitro potency and reduction potential

Resistance against novel anticancer metal compounds: differences and similarities

Ruthenium− and Osmium−Arene Complexes of 2-Substituted Indolo[3,2-c]quinolines: Synthesis, Structure, Spectroscopic Properties, and Antiproliferative Activity ⬇️

Solid-phase synthesis of oxaliplatin-TAT peptide bioconjugates.

Synthesis and characterization of novel bis(carboxylato)dichloridobis(ethylamine)platinum(IV) complexes with higher cytotoxicity than cisplatin

Synthesis and in vitro antitumor potency of (cyclohexane-1,2-diamine)platinum(II) complexes with aminotris(methylenephosphonic acid) as bone-seeking ligand

Synthesis, characterization, and cytotoxic activity of novel potentially pH-sensitive nonclassical platinum(II) complexes featuring 1,3-dihydroxyacetone oxime ligands.

Synthesis, crystal structure and cytotoxicity of new oxaliplatin analogues indicating that improvement of anticancer activity is still possible.

Synthesis, structure, spectroscopic and in vitro antitumour studies of a novel gallium(III) complex with 2-acetylpyridine (4)N-dimethylthiosemicarbazone.

Tetracarboxylatoplatinum(IV) complexes featuring monodentate leaving groups - A rational approach toward exploiting the platinum(IV) prodrug strategy

The first metal-based paullone derivative with high antiproliferative activity in vitro.

The first ruthenium-based paullones: syntheses, X-ray diffraction structures, and spectroscopic and antiproliferative properties in vitro

The role of the equatorial ligands for the redox behavior, mode of cellular accumulation and cytotoxicity of platinum(IV) prodrugs.

Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes

Unsymmetric mono- and dinuclear platinum(IV) complexes featuring an ethylene glycol moiety: synthesis, characterization, and biological activity

Water-soluble cationic derivatives of indirubin, the active anticancer component from Indigo naturalis

{(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo