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A TRPC1 protein-dependent pathway regulates osteoclast formation and function.

scientific article published on 14 June 2013

A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling

artículo científico publicado en 2015

A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide

artículo científico publicado en 2011

A comparison of the genes coding for canonical TRP channels and their M, V and P relatives

scientific article published on 01 May 2003

Activation of endothelial transient receptor potential C3 channel is required for small conductance calcium-activated potassium channel activation and sustained endothelial hyperpolarization and vasodilation of cerebral artery.

artículo científico publicado en 2014

Analysis of Mrgprb2 Receptor-Evoked Ca 2+ Signaling in Bone Marrow Derived (BMMC) and Peritoneal (PMC) Mast Cells of TRPC-Deficient Mice

scientific article published on 08 April 2020

Angiotensin-II-Evoked Ca2+ Entry in Murine Cardiac Fibroblasts Does Not Depend on TRPC Channels

artículo científico publicado en 2020

Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice

scientific journal article

Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter

artículo científico publicado en 2013

Ca2+ entry via TRPC1 is essential for cellular differentiation and modulates secretion via the SNARE complex

scientific article published on 01 July 2019

Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms

artículo científico publicado en 2012

Canonical transient receptor potential 3 channels regulate mitochondrial calcium uptake

artículo científico publicado en 2013

Characterization of zfs1 as an mRNA-binding and -destabilizing protein in Schizosaccharomyces pombe

artículo científico publicado en 2007

Critical role of canonical transient receptor potential channel 7 in initiation of seizures.

artículo científico publicado en 2014

Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca2+*Calmodulin Displays a Unique Binding Mode

artículo científico publicado en 2012

Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo.

artículo científico publicado en 2009

Deletion of diacylglycerol-responsive TRPC genes attenuates diabetic nephropathy by inhibiting activation of the TGFβ1 signaling pathway

artículo científico publicado en 2017

Does Erythropoietin Regulate TRPC Channels in Red Blood Cells?

artículo científico publicado en 2017

Evidence for a regulated Ca2+ entry in proximal tubular cells and its implication in calcium stone formation

scientific article published on 30 April 2019

Evidence for functional coupling of cGMP/cGKI signalling and TRPC channels in endothelium but not in vascular smooth muscle.

artículo científico publicado en 2013

Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels

artículo científico publicado en 2008

Heteromeric TRPV4-C1 channels contribute to store-operated Ca2+ entry in vascular endothelial cells

artículo científico publicado el 18 de septiembre de 2011

Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration

artículo científico publicado en 2011

Increased Vascular Smooth Muscle Contractility in TRPC6−/− Mice

artículo científico publicado en 2005

Increased vascular smooth muscle contractility in TRPC6-/- mice

artículo científico publicado en 2005

Inhibition of L-Type Ca2+ Channels by TRPC1-STIM1 Complex Is Essential for the Protection of Dopaminergic Neurons.

artículo científico publicado en 2017

Knockout of the Trpc1 gene reveals that TRPC1 can promote recovery from anaphylaxis by negatively regulating mast cell TNF-α production

artículo científico publicado en 2013

Lipid-independent control of endothelial and neuronal TRPC3 channels by light

artículo científico publicado en 2019

M1 Macrophage Polarization Is Dependent on TRPC1-Mediated Calcium Entry

Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries

artículo científico publicado en 2017

Mechanism of stretch-induced activation of the mechanotransducer zyxin in vascular cells

artículo científico publicado en 2012

Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels

artículo científico publicado en 2014

Molecular cloning of TRPC3a, an N-terminally extended, store-operated variant of the human C3 transient receptor potential channel.

artículo científico publicado en 2005

Murine cardiac growth, TRPC channels, and cGMP kinase I.

artículo científico publicado en 2014

NMDA receptor-dependent synaptic activation of TRPC channels in olfactory bulb granule cells

artículo científico publicado en 2012

Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling

artículo científico publicado en 2012

Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2.

artículo científico publicado en 2010

Orai proteins interact with TRPC channels and confer responsiveness to store depletion.

artículo científico publicado en 2007

Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells.

artículo científico publicado en 2010

Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1

scientific journal article

RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways

scientific article published on 29 April 2020

Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor- and store-operated Ca2+ entry channels

artículo científico publicado en 2006

Role of TRPC1 channel in skeletal muscle function

artículo científico publicado en 2009

Severely blunted allergen-induced pulmonary Th2 cell response and lung hyperresponsiveness in type 1 transient receptor potential channel-deficient mice.

artículo científico publicado en 2012

TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation

artículo científico publicado en 2012

TRPC1 regulates calcium-activated chloride channels in salivary gland cells

artículo científico publicado en 2015

TRPC1- and TRPC3-dependent Ca2+ signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo

artículo científico publicado en 2017

TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells

artículo científico publicado en 2012

TRPC3 channels are required for synaptic transmission and motor coordination

artículo científico publicado en 2008

TRPC3 channels play a critical role in the theta component of pilocarpine-induced status epilepticus in mice

artículo científico publicado en 2016

TRPC3/6/7 Knockdown Protects the Brain from Cerebral Ischemia Injury via Astrocyte Apoptosis Inhibition and Effects on NF-кB Translocation

artículo científico publicado en 2016

TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response

artículo científico publicado en 2015

The TRPC Family of Ion Channels: Relation to the TRP Superfamily and Role in Receptor- and Store-Operated Calcium Entry

artículo científico publicado el 5 de enero de 2011

The TRPC family of TRP channels: roles inferred (mostly) from knockout mice and relationship to ORAI proteins

artículo científico publicado en 2014

The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing

artículo científico publicado en 2015

The mouse C-type transient receptor potential 2 (TRPC2) channel: alternative splicing and calmodulin binding to its N terminus

scientific journal article

The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone

artículo científico publicado en 2013

Transient Receptor Potential Channel 1 Deficiency Impairs Host Defense and Proinflammatory Responses to Bacterial Infection by Regulating Protein Kinase Cα Signaling

artículo científico publicado en 2015

Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity

artículo científico publicado en 2012

Transient receptor potential channel 6 knockdown prevents apoptosis of renal tubular epithelial cells upon oxidative stress via autophagy activation

artículo científico publicado en 2018

Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure.

artículo científico publicado en 2013

Trpc1 ion channel modulates phosphatidylinositol 3-kinase/Akt pathway during myoblast differentiation and muscle regeneration.

artículo científico publicado en 2012

Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus

artículo científico publicado en 2020

XLalphas, the extra-long form of the alpha-subunit of the Gs G protein, is significantly longer than suspected, and so is its companion Alex

artículo científico publicado en 2004