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"End-stage" neurofibrillary tangle pathology in preclinical Alzheimer's disease: fact or fiction?

artículo científico publicado en 2011

"From Victimhood to Warriors": Super-researchers' Insights Into Alzheimer's Disease Clinical Trial Participation Motivations

scientific article published on 19 July 2019

"New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS).

artículo científico publicado en 2016

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

artículo científico publicado en 2018

A Comparison of Sex Differences in Psychotropic Medication Use in Older People with Alzheimer's Disease in the US and Finland

artículo científico publicado en 2016

A Conformation‐ and Phosphorylation‐Dependent Antibody Recognizing the Paired Helical Filaments of Alzheimer's Disease

artículo científico publicado el 1 de noviembre de 1997

A Customized Quantitative PCR MicroRNA Panel Provides a Technically Robust Context for Studying Neurodegenerative Disease Biomarkers and Indicates a High Correlation Between Cerebrospinal Fluid and Choroid Plexus MicroRNA Expression.

artículo científico publicado en 2016

A Randomized Controlled Trial of Anesthesia Guided by Bispectral Index Versus Standard Care: Effects on Cognition

scientific article published on 01 April 2019

A clinical trial to validate event-related potential markers of Alzheimer's disease in outpatient settings.

artículo científico publicado en 2015

A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging

scientific article published on 19 January 2017

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

artículo científico publicado en 2014

ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target

artículo científico publicado en 2015

APOE DNA methylation is altered in Lewy body dementia.

artículo científico publicado en 2018

APOE ε4 increases risk for dementia in pure synucleinopathies

artículo científico publicado en 2013

APOE-ε2 and APOE-ε4 correlate with increased amyloid accumulation in cerebral vasculature

artículo científico publicado en 2013

Acetylcholinesterase inhibitor treatment is associated with relatively slow cognitive decline in patients with Alzheimer's disease and AD + DLB

artículo científico publicado en 2009

Adjusting for mortality when identifying risk factors for transitions to mild cognitive impairment and dementia

artículo científico publicado en 2013

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

artículo científico publicado en 2014

Age and apoE associations with complex pathologic features in Alzheimer's disease

artículo científico publicado en 2008

Age-Related Changes in Headache Days across the Cognitive Spectrum.

artículo científico publicado en 2017

Age-related slowing of task switching is associated with decreased integrity of frontoparietal white matter

artículo científico publicado en 2008

Aging influences the neural correlates of lexical decision but not automatic semantic priming

scientific article published on 08 March 2009

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

artículo científico publicado en 2015

Altered cargo proteins of human plasma endothelial cell-derived exosomes in atherosclerotic cerebrovascular disease.

artículo científico publicado en 2017

Alzheimer Disease Clinical Trial Recruitment: Does Participation in a Brief Cognitive Screen at a Community Health Fair Promote Research Engagement?

artículo científico publicado en 2018

Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene

artículo científico publicado en 2020

Alzheimer Disease Worries, Fears, and Stigma and Their Relationship to Genetic and Interventional Research Engagement

scientific article published on 21 September 2020

Alzheimer disease: can the exam predict the pathology?

artículo científico publicado en 2012

Alzheimer's Biomarkers are Correlated with Brain Connectivity in Older Adults Differentially during Resting and Task States.

artículo científico publicado en 2016

Alzheimer's disease is not "brain aging": neuropathological, genetic, and epidemiological human studies

artículo científico publicado en 2011

Alzheimer's-type neuropathology in the precuneus is not increased relative to other areas of neocortex across a range of cognitive impairment

artículo científico publicado en 2008

Analysis of shared heritability in common disorders of the brain

artículo científico publicado en 2018

Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures

artículo científico publicado en 2012

Argyrophilic grain disease in demented subjects presenting initially with amnestic mild cognitive impairment

artículo científico publicado en 2006

Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing

artículo científico publicado en 2013

Assessing the discriminant ability, reliability, and comparability of multiple short forms of the Boston Naming Test in an Alzheimer's disease center cohort

artículo científico publicado en 2015

Association between male gender and cortical Lewy body pathology in large autopsy series

artículo científico publicado en 2010

Association of Subjective Hearing Loss and Apolipoprotein E ε4 Allele on Alzheimer's Disease Neurodegeneration

artículo científico publicado en 2021

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

artículo científico publicado en 2012

Attention-deficit/hyperactivity disorder in childhood is associated with cognitive test profiles in the geriatric population but not with mild cognitive impairment or Alzheimer's disease

artículo científico publicado en 2011

Attention-deficit/hyperactivity disorder in older adults: prevalence and possible connections to mild cognitive impairment

artículo científico publicado en 2012

Aβ efflux impairment and inflammation linked to cerebrovascular accumulation of amyloid-forming amylin secreted from pancreas

artículo científico publicado en 2023

Behaviors Characteristic of Autism Spectrum Disorder in a Geriatric Cohort With Mild Cognitive Impairment or Early Dementia

artículo científico publicado en 2020

Bladder antimuscarinics and cognitive decline in elderly patients

artículo científico

Blood serum miRNA: non-invasive biomarkers for Alzheimer's disease

artículo científico publicado en 2011

Brain arteriolosclerosis

artículo científico publicado en 2020

Brain pathologies in extreme old age.

artículo científico publicado en 2015

Brain structural alterations before mild cognitive impairment

artículo científico publicado en 2007

Brain structure changes over time in normal and mildly impaired aged persons

artículo científico publicado en 2020

Brains with medial temporal lobe neurofibrillary tangles but no neuritic amyloid plaques are a diagnostic dilemma but may have pathogenetic aspects distinct from Alzheimer disease.

artículo científico publicado en 2009

COVID-19 and geriatric clinical trials research

scientific article published on 16 September 2020

COVID-19 and the neurological disease therapeutic pipeline

scientific article published on 18 December 2020

Cardiorespiratory fitness diminishes the effects of age on white matter hyperintensity volume

scientific article published on 31 August 2020

Cerebrospinal fluid vascular endothelial growth factor

artículo científico publicado en 2015

Challenges and Considerations Related to Studying Dementia in Blacks/African Americans

artículo científico

Clinical features of mild cognitive impairment differ in the research and tertiary clinic settings

artículo científico publicado en 2008

Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity

artículo científico publicado en 2007

Cognitive and brain reserve and the diagnosis and treatment of preclinical Alzheimer disease

artículo científico publicado en 2013

Comment: Telomeres in AD--the long and the short of it

artículo científico publicado en 2012

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

artículo científico publicado en 2011

Comparison of behaviors characteristic of autism spectrum disorder behaviors and behavioral and psychiatric symptoms of dementia

artículo científico publicado en 2020

Comparison of recruitment efforts targeted at primary care physicians versus the community at large for participation in Alzheimer disease clinical trials

artículo científico publicado en 2010

Conceptual evolution in Alzheimer's disease: implications for understanding the clinical phenotype of progressive neurodegenerative disease

artículo científico publicado en 2010

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

artículo científico publicado en 2012

Declining levels of functionally specialized synaptic proteins in plasma neuronal exosomes with progression of Alzheimer's disease

artículo científico publicado en 2017

Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease

artículo científico publicado en 2016

Dementia for the Primary Care Provider.

artículo científico publicado en 2017

Depression, Apolipoprotein E Genotype, and the Incidence of Mild Cognitive Impairment

article

Development of 1H MRS biomarkers for tracking early predementia Alzheimer disease

scientific article published on 04 January 2019

Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease

artículo científico publicado en 2016

Diagnostic accuracy and practice effects in the National Alzheimer's Coordinating Center Uniform Data Set neuropsychological battery

artículo científico publicado en 2014

Diagnostic and Prognostic Laboratory Testing for Alzheimer Disease

artículo científico publicado en 2020

Differential reports of pain and depression differentiate mild cognitive impairment from cognitively intact elderly participants

artículo científico publicado en 2012

Diffuse Amyloid-β Plaques, Neurofibrillary Tangles, and the Impact of APOE in Elderly Persons' Brains Lacking Neuritic Amyloid Plaques

artículo científico publicado en 2018

Diffuse Optical Assessment of Cerebral-autoregulation in Older Adults Stratified by Cerebrovascular Risk

artículo científico publicado en 2020

Discrimination of mild cognitive impairment and Alzheimer's disease using transfer entropy measures of scalp EEG.

artículo científico publicado en 2015

Distinct White Matter Changes Associated with Cerebrospinal Fluid Amyloid-β1 - 42 and Hypertension

artículo científico publicado en 2018

Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance

artículo científico publicado en 2013

EEG changes in a patient with steroid-responsive encephalopathy associated with antibodies to thyroperoxidase (SREAT, Hashimoto's encephalopathy).

artículo científico publicado en 2006

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

artículo científico publicado en 2014

Electrophysiological repetition effects in persons with mild cognitive impairment depend upon working memory demand

artículo científico publicado en 2018

Endothelial-derived plasma exosome proteins in Alzheimer's disease angiopathy

scientific article published on 10 March 2020

Extracellular Vesicle-Associated Aβ Mediates Trans-Neuronal Bioenergetic and Ca2+-Handling Deficits in Alzheimer's Disease Models

artículo científico publicado en 2016

Frontal white matter integrity in adults with Down syndrome with and without dementia

scientific article published on 04 February 2014

Functional human GRIN2B promoter polymorphism and variation of mental processing speed in older adults.

artículo científico publicado en 2017

Functional response in ventral temporal cortex differentiates mild cognitive impairment from normal aging.

artículo científico publicado en 2010

GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology

artículo científico publicado en 2012

Genetic Sample Provision Among National Alzheimer's Coordinating Center Participants

Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging

artículo científico publicado en 2016

Global Cerebral Atrophy Detected by Routine Imaging: Relationship with Age, Hippocampal Atrophy, and White Matter Hyperintensities.

artículo científico publicado en 2018

Hierarchical Clustering Analyses of Plasma Proteins in Subjects With Cardiovascular Risk Factors Identify Informative Subsets Based on Differential Levels of Angiogenic and Inflammatory Biomarkers

artículo científico publicado en 2020

High complement levels in astrocyte-derived exosomes of Alzheimer's disease

artículo científico publicado en 2018

Hippocampal Sclerosis but Not Normal Aging or Alzheimer Disease Is Associated With TDP-43 Pathology in the Basal Forebrain of Aged Persons

scientific article published on 12 March 2016

Hippocampal Sclerosis in Older Patients: Practical Examples and Guidance With a Focus on Cerebral Age-Related TDP-43 With Sclerosis

artículo científico publicado en 2017

Hippocampal Sclerosis of Aging Can Be Segmental: Two Cases and Review of the Literature

artículo científico publicado en 2015

Hippocampal Sclerosis, Argyrophilic Grain Disease, and Primary Age-Related Tauopathy

scientific article published on 01 February 2019

Hippocampal sclerosis in advanced age: clinical and pathological features.

artículo científico publicado en 2011

Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease

artículo científico publicado en 2013

Human cerebral neuropathology of Type 2 diabetes mellitus

artículo científico publicado en 2008

INSIGHTS FROM AFRICAN AMERICAN OLDER ADULTS ON BRAIN HEALTH RESEARCH ENGAGEMENT: NEED TO SEE THE NEED

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

INtervention for Cognitive Reserve Enhancement in delaying the onset of Alzheimer's Symptomatic Expression (INCREASE), a randomized controlled trial: rationale, study design, and protocol

artículo científico publicado en 2019

Identifying Adaptive and Maladaptive Behaviors Following a Diagnosis of Mild Cognitive Impairment

artículo científico publicado en 2020

Innovation in Stroke Care Quality: NIH Stroke Scale Change and Shewhart Charts

artículo científico publicado en 2015

Insights From African American Older Adults on Brain Health Research Engagement: "Need to See the Need"

scientific article published on 04 February 2020

Is passive immunization for Alzheimer's disease 'alive and well' or 'dead and buried'?

artículo científico publicado en 2009

Lewy body pathology in normal elderly subjects

artículo científico publicado en 2009

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.

artículo científico publicado en 2019

Limbic-predominant age-related TDP-43 encephalopathy differs from frontotemporal lobar degeneration

scientific article published on 24 August 2020

Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia

artículo científico publicado en 2017

Low Arousal Positive Emotional Stimuli Attenuate Aberrant Working Memory Processing in Persons with Mild Cognitive Impairment

artículo científico publicado en 2017

Low sensitivity in clinical diagnoses of dementia with Lewy bodies

artículo científico publicado en 2009

Management of frontotemporal dementia: targeting symptom management in such a heterogeneous disease requires a wide range of therapeutic options

artículo científico

Maximizing Safety in the Conduct of Alzheimer's Disease Fluid Biomarker Research in the Era of COVID-19

scientific article published on 19 June 2020

Medical management of frontotemporal dementias: the importance of the caregiver in symptom assessment and guidance of treatment strategies

artículo científico publicado en 2011

Memory-Related Frontal Brainwaves Predict Transition to Mild Cognitive Impairment in Healthy Older Individuals Five Years Before Diagnosis

artículo científico publicado en 2020

Mild cognitive impairment: statistical models of transition using longitudinal clinical data

artículo científico publicado en 2012

Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons

artículo científico publicado en 2008

Motivators for Alzheimer's disease clinical trial participation

artículo científico

Musical Training and Late-Life Cognition.

artículo científico publicado en 2013

Neuropathologic features of amnestic mild cognitive impairment

artículo científico publicado en 2006

Neuropathologic outcome of mild cognitive impairment following progression to clinical dementia

artículo científico publicado en 2006

Neuropathological Findings of Dementia Associated With Subjective Hearing Loss

scientific article published on 01 October 2019

Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis

artículo científico publicado en 2017

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

artículo científico publicado en 2012

Nutrition and prevention of Alzheimer's dementia

artículo científico publicado en 2014

Omega-3 fatty acids: potential role in the management of early Alzheimer's disease

artículo científico publicado en 2010

One-Year Evaluation of a Targeted Medication Therapy Management Intervention for Older Adults

artículo científico publicado en 2020

Optimizing medication appropriateness in older adults: a randomized clinical interventional trial to decrease anticholinergic burden.

artículo científico publicado en 2017

Outcomes after diagnosis of mild cognitive impairment in a large autopsy series

artículo científico publicado en 2017

PART, a distinct tauopathy, different from classical sporadic Alzheimer disease

artículo científico publicado en 2015

Peripheral (deep) but not periventricular MRI white matter hyperintensities are increased in clinical vascular dementia compared to Alzheimer's disease

artículo científico publicado en 2016

Perspectives of African American Older Adults on Brain Health: "Brains Get Tired Too"

scientific article published on 01 October 2019

Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal aging

artículo científico publicado en 2016

Post-acquisition processing confounds in brain volumetric quantification of white matter hyperintensities

artículo científico publicado en 2019

Preclinical AD Workgroup staging: pathological correlates and potential challenges.

artículo científico publicado en 2011

Prediction of preclinical Alzheimer's disease: longitudinal rates of change in cognition

artículo científico publicado en 2011

Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults

scientific article published on 22 June 2020

Primary age-related tauopathy (PART): a common pathology associated with human aging

artículo científico publicado en 2014

Primary diffuse leptomeningeal gliomatosis.

artículo científico publicado en 2009

Prodromal clinical manifestations of neuropathologically confirmed Lewy body disease

artículo científico publicado en 2008

Pseudotumor cerebri reversed by cardiac septal defect repair

artículo científico publicado en 2003

Public Understanding and Opinions regarding Genetic Research on Alzheimer's Disease

artículo científico publicado en 2018

Rapid, scalable assay of amylin-β amyloid co-aggregation in brain tissue and blood

artículo científico publicado en 2023

Rapid, scalable assay of amylin‐β amyloid co‐aggregation in brain tissue and blood

artículo científico publicado en 2023

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

artículo científico publicado en 2015

Real-world Site Experiences With GeneMatch: The Role of a Recruitment-related Registry in the Context of Local Site Effort to Support Alzheimer Disease Prevention Research

artículo científico publicado en 2020

Relative preservation of MMSE scores in autopsy-proven dementia with Lewy bodies

artículo científico publicado en 2009

Repeated retrieval during working memory is sensitive to amnestic mild cognitive impairment.

scientific article published on 30 September 2013

Reply: LATE to the PART-y

artículo científico publicado en 2019

Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria

artículo científico publicado en 2007

Resting EEG discrimination of early stage Alzheimer's disease from normal aging using inter-channel coherence network graphs.

artículo científico publicado en 2013

Revising the definition of Alzheimer's disease: a new lexicon.

artículo científico publicado en 2010

Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals

artículo científico publicado en 2016

Rural Caregivers: Identification of Informational Needs Through Telemedicine Questions

scientific article published on 03 April 2020

Rural-Urban Differences in Alzheimer's Disease and Related Disorders Diagnostic Prevalence in Kentucky and West Virginia

scientific article published on 30 October 2015

Screening for C9ORF72 repeat expansion in FTLD.

artículo científico publicado en 2012

Self-Reported Memory Complaints: A Comparison of Demented and Unimpaired Outcomes

artículo científico publicado en 2016

Self-Reported Sleep Apnea and Dementia Risk: Findings from the Prevention of Alzheimer's Disease with Vitamin E and Selenium Trial

artículo científico publicado en 2016

Self-reported head injury and risk of late-life impairment and AD pathology in an AD center cohort

artículo científico publicado en 2014

Self-reported memory complaints: implications from a longitudinal cohort with autopsies

artículo científico publicado en 2014

Serum antibodies to periodontal pathogens are a risk factor for Alzheimer's disease

artículo científico publicado en 2012

Spared behavioral repetition effects in Alzheimer's disease linked to an altered neural mechanism at posterior cortex.

artículo científico publicado en 2018

Spectral and complexity analysis of scalp EEG characteristics for mild cognitive impairment and early Alzheimer's disease.

artículo científico publicado en 2014

Subjective Memory Complaints Are an Important Surrogate for Objective Cognitive Performance in African Americans

artículo científico publicado en 2020

Substantia nigra depigmentation and exposure to encephalitis lethargica.

artículo científico publicado en 2012

Sugihara causality analysis of scalp EEG for detection of early Alzheimer's disease

artículo científico publicado en 2014

TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels

scientific article published on 23 January 2019

Task deactivation reductions and atrophy within parietal default mode regions are overlapping but only weakly correlated in mild cognitive impairment

artículo científico publicado en 2011

The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases

artículo científico publicado en 2017

The Effectiveness of Small-group Community-based Information Sessions on Clinical Trial Recruitment for Secondary Prevention of Alzheimer's Disease

artículo científico publicado en 2016

Tobacco Smoking and Dementia in a Kentucky Cohort: A Competing Risk Analysis

artículo científico publicado en 2019

University of Kentucky Sanders-Brown healthy brain aging volunteers: donor characteristics, procedures and neuropathology

artículo científico publicado en 2012

Version 3 of the National Alzheimer's Coordinating Center's Uniform Data Set

artículo científico publicado en 2018

Visual Arts Education improves self-esteem for persons with dementia and reduces caregiver burden: A randomized controlled trial.

artículo científico publicado en 2018

White Matter Hyperintensity Associations with Cerebral Blood Flow in Elderly Subjects Stratified by Cerebrovascular Risk

artículo científico publicado en 2017

White Matter Hyperintensity Regression: Comparison of Brain Atrophy and Cognitive Profiles with Progression and Stable Groups

scientific article published on 19 July 2019

White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults.

artículo científico publicado en 2014

Will "social distancing" lead to future "research distancing": A reflection on COVID-19 impacts on Alzheimer's disease research

scientific article published on 03 August 2020