Lista de obras -

"Dynamic range" of inferred phenotypic HIV drug resistance values in clinical practice

artículo científico publicado en 2011

A Simple, Dynamic Measure of Antiretroviral Therapy Adherence Predicts Failure to Maintain HIV‐1 Suppression

article

A comparison of three computational modelling methods for the prediction of virological response to combination HIV therapy

artículo científico publicado en 2009

A compromise strategy for patients with multiple drug failure

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes

artículo científico publicado en 2013

Adaptation of HIV-1 to human leukocyte antigen class I

artículo científico publicado en 2009

Antiretroviral Concentrations in Untimed Plasma Samples Predict Therapy Outcome in a Population with Advanced Disease

article

Antiretroviral resistance among HIV-infected persons who have died in British Columbia, in the era of modern antiretroviral therapy

artículo científico publicado en 2004

Application and validation of case-finding algorithms for identifying individuals with human immunodeficiency virus from administrative data in British Columbia, Canada

artículo científico publicado en 2013

Association between HIV-1 RNA level and CD4 cell count among untreated HIV-infected individuals

article

Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based study

artículo científico publicado en 2010

CD4-dependent characteristics of coreceptor use and HIV type 1 V3 sequence in a large population of therapy-naive individuals

artículo científico publicado en 2008

Clinical and immunological impact of HIV envelope V3 sequence variation after starting initial triple antiretroviral therapy

artículo científico publicado en 2004

Cohort Profile: HAART Observational Medical Evaluation and Research (HOMER) cohort

artículo científico publicado en 2014

Continued improvement in survival among HIV-infected individuals with newer forms of highly active antiretroviral therapy

artículo científico publicado en 2007

Correction: Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1

article

Correction: Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis

artículo científico publicado en 2015

Cost-Effectiveness of Antiretroviral Therapy for Multidrug-Resistant HIV: Past, Present, and Future ⬇️

artículo científico publicado el 8 de noviembre de 2012

Development and validation of a composite programmatic assessment tool for HIV therapy

artículo científico publicado en 2012

Differential impact of adherence on long-term treatment response among naive HIV-infected individuals

article

Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection

artículo científico publicado en 2010

Effect of Medication Adherence on Survival of HIV-Infected Adults Who Start Highly Active Antiretroviral Therapy When the CD4+ Cell Count Is 0.200 to 0.350 × 109 cells/L

artículo científico publicado el 18 de noviembre de 2003

Effects of Human Leukocyte Antigen Class I Genetic Parameters on Clinical Outcomes and Survival after Initiation of Highly Active Antiretroviral Therapy

article

Emergence of drug resistance is associated with an increased risk of death among patients first starting HAART

artículo científico publicado en 2006

Epidemiology of treatment failure: a focus on recent trends

artículo científico publicado en 2009

Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1

artículo científico publicado en 2007

Expanded access to highly active antiretroviral therapy: a potentially powerful strategy to curb the growth of the HIV epidemic

artículo científico publicado en 2008

Expanded highly active antiretroviral therapy coverage among HIV-positive drug users to improve individual and public health outcomes

artículo científico publicado en 2010

Expansion of HAART coverage is associated with sustained decreases in HIV/AIDS morbidity, mortality and HIV transmission: the "HIV Treatment as Prevention" experience in a Canadian setting

artículo científico publicado en 2014

Full suppression of viral load is needed to achieve an optimal CD4 cell count response among patients on triple drug antiretroviral therapy

article

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis

artículo científico publicado en 2015

HIV antiviral drug resistance: patient comprehension

artículo científico publicado en 2010

HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins

artículo científico publicado en 2009

HLA-associated viral mutations are common in human immunodeficiency virus type 1 elite controllers

artículo científico publicado en 2009

Hepatitis C testing in Canada: don't leave baby boomers behind.

artículo científico publicado en 2017

Higher baseline levels of plasma human immunodeficiency virus type 1 RNA are associated with increased mortality after initiation of triple-drug antiretroviral therapy

artículo científico publicado en 2003

Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection

article

Impact of baseline viral load and adherence on survival of HIV-infected adults with baseline CD4 cell counts ≥ 200 cells/μl

article

Improved virological outcomes in British Columbia concomitant with decreasing incidence of HIV type 1 drug resistance detection

artículo científico publicado en 2010

Increased Prevalence of Controlled Viremia and Decreased Rates of HIV Drug Resistance Among HIV-Positive People Who Use Illicit Drugs During a Community-wide Treatment-as-Prevention Initiative

artículo científico publicado en 2015

Increased reporting of detectable plasma HIV-1 RNA levels at the critical threshold of 50 copies per milliliter with the Taqman assay in comparison to the Amplicor assay

artículo científico publicado en 2009

Increased resilience to the development of drug resistance with modern boosted protease inhibitor-based highly active antiretroviral therapy

artículo científico publicado en 2008

Initiation of antiretroviral therapy at high CD4+ cell counts is associated with positive treatment outcomes

artículo científico publicado en 2015

Is nevirapine-based therapy discontinuation in hepatitis C co-infected patients a more important mortality determinant than hypersensitivity: authors' reply

artículo científico publicado en 2008

Is there a baseline CD4 cell count that precludes a survival response to modern antiretroviral therapy?

artículo científico publicado en 2003

Longitudinal community plasma HIV-1 RNA concentrations and incidence of HIV-1 among injecting drug users: prospective cohort study.

artículo científico publicado en 2009

Lower prevalence of drug resistance mutations at first-line virological failure to first-line therapy with atripla vs. tenofovir + emtricitabine/lamivudine + efavirenz administered on a multiple tablet therapy

artículo científico publicado en 2014

Magnitude of Virologic Blips Is Associated With a Higher Risk for Virologic Rebound in HIV-Infected Individuals: A Recurrent Events Analysis ⬇️

artículo científico publicado el 15 de abril de 2012

Mitochondrial DNA somatic mutation burden and heteroplasmy are associated with chronological age, smoking, and HIV infection

artículo científico publicado en 2019

Mitochondrial toxicity in the era of HAART: evaluating venous lactate and peripheral blood mitochondrial DNA in HIV-infected patients taking antiretroviral therapy

artículo científico publicado en 2003

Mitochondrial:nuclear DNA ratios in peripheral blood cells from human immunodeficiency virus (HIV)-infected patients who received selected HIV antiretroviral drug regimens

artículo científico publicado en 2003

Molecular and Clinical Epidemiology of CXCR4‐Using HIV‐1 in a Large Population of Antiretroviral‐Naive Individuals

article

Near real-time monitoring of HIV transmission hotspots from routine HIV genotyping: an implementation case study

artículo científico publicado en 2016

Nucleoside-related mitochondrial toxicity among HIV-infected patients receiving antiretroviral therapy: insights from the evaluation of venous lactic acid and peripheral blood mitochondrial DNA.

artículo científico publicado en 2004

Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.

artículo científico publicado en 2008

Post-marketing experience with nevirapine extended release (XR) tablets: effectiveness and tolerability in a population-based cohort in British Columbia, Canada

artículo científico publicado en 2014

Predicting hospitalization among HIV-infected antiretroviral naïve patients starting HAART: determining clinical markers and exploring social pathways

artículo científico publicado en 2008

Predictors of HIV drug-resistance mutations in a large antiretroviral-naive cohort initiating triple antiretroviral therapy

artículo científico publicado en 2004

Rates of antiretroviral resistance among HIV-infected patients with and without a history of injection drug use.

artículo científico publicado en 2005

Rates of disease progression among human immunodeficiency virus-infected persons initiating multiple-drug rescue therapy

artículo científico publicado en 2003

Regional differences in rates of HIV-1 viral load monitoring in Canada: Insights and implications for antiretroviral care in high income countries

artículo científico publicado en 2010

Relative effects of antiretroviral therapy and harm reduction initiatives on HIV incidence in British Columbia, Canada, 1996-2013: a modelling study

artículo científico publicado en 2017

Risk of viral failure declines with duration of suppression on highly active antiretroviral therapy irrespective of adherence level

artículo científico publicado en 2010

Short communication. Association of the CCR5delta32 mutation with clinical response and >5-year survival following initiation of first triple antiretroviral regimen

article

Tenofovir and emtricitabine resistance among antiretroviral-naive patients in the Canadian Observational Cohort Collaboration: implications for PrEP

scientific article published on 01 January 2019

The Impact of Adherence on CD4 Cell Count Responses Among HIV-Infected Patients

article

The case for expanding access to highly active antiretroviral therapy to curb the growth of the HIV epidemic

artículo científico publicado en 2006

The combined effect of modern highly active antiretroviral therapy regimens and adherence on mortality over time

artículo científico publicado en 2009

The development of an expert system to predict virological response to HIV therapy as part of an online treatment support tool

artículo científico publicado en 2011

The development of artificial neural networks to predict virological response to combination HIV therapy.

artículo científico publicado en 2007

The impact of clinical, demographic and risk factors on rates of HIV transmission: a population-based phylogenetic analysis in British Columbia, Canada

artículo científico publicado en 2014

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

artículo científico publicado en 2010

The relationship between resistance and adherence in drug-naive individuals initiating HAART is specific to individual drug classes

artículo científico publicado en 2008

Treatment interruption of highly active antiretroviral therapy in patients with nadir CD4 cell counts >200 cells/mm3.

artículo científico publicado en 2005

Trends in plasma HIV-RNA suppression and antiretroviral resistance in British Columbia, 1997-2010

artículo científico publicado en 2014

Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity

artículo científico publicado en 2012

Using baseline CD4 cell count and plasma HIV RNA to guide the initiation of highly active antiretroviral therapy

artículo científico publicado en 2004

When to initiate antiretroviral therapy in HIV-1-infected adults: a review for clinicians and patients

artículo científico publicado en 2005

Lista de obras de

"Dynamic range" of inferred phenotypic HIV drug resistance values in clinical practice

A Simple, Dynamic Measure of Antiretroviral Therapy Adherence Predicts Failure to Maintain HIV‐1 Suppression

A comparison of three computational modelling methods for the prediction of virological response to combination HIV therapy

A compromise strategy for patients with multiple drug failure

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes

Adaptation of HIV-1 to human leukocyte antigen class I

Antiretroviral Concentrations in Untimed Plasma Samples Predict Therapy Outcome in a Population with Advanced Disease

Antiretroviral resistance among HIV-infected persons who have died in British Columbia, in the era of modern antiretroviral therapy

Application and validation of case-finding algorithms for identifying individuals with human immunodeficiency virus from administrative data in British Columbia, Canada

Association between HIV-1 RNA level and CD4 cell count among untreated HIV-infected individuals

Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based study

CD4-dependent characteristics of coreceptor use and HIV type 1 V3 sequence in a large population of therapy-naive individuals

Clinical and immunological impact of HIV envelope V3 sequence variation after starting initial triple antiretroviral therapy

Cohort Profile: HAART Observational Medical Evaluation and Research (HOMER) cohort

Continued improvement in survival among HIV-infected individuals with newer forms of highly active antiretroviral therapy

Correction: Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1

Correction: Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis

Cost-Effectiveness of Antiretroviral Therapy for Multidrug-Resistant HIV: Past, Present, and Future ⬇️

Development and validation of a composite programmatic assessment tool for HIV therapy

Differential impact of adherence on long-term treatment response among naive HIV-infected individuals

Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection

Effect of Medication Adherence on Survival of HIV-Infected Adults Who Start Highly Active Antiretroviral Therapy When the CD4+ Cell Count Is 0.200 to 0.350 × 109 cells/L

Effects of Human Leukocyte Antigen Class I Genetic Parameters on Clinical Outcomes and Survival after Initiation of Highly Active Antiretroviral Therapy

Emergence of drug resistance is associated with an increased risk of death among patients first starting HAART

Epidemiology of treatment failure: a focus on recent trends

Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1

Expanded access to highly active antiretroviral therapy: a potentially powerful strategy to curb the growth of the HIV epidemic

Expanded highly active antiretroviral therapy coverage among HIV-positive drug users to improve individual and public health outcomes

Expansion of HAART coverage is associated with sustained decreases in HIV/AIDS morbidity, mortality and HIV transmission: the "HIV Treatment as Prevention" experience in a Canadian setting

Full suppression of viral load is needed to achieve an optimal CD4 cell count response among patients on triple drug antiretroviral therapy

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis

HIV antiviral drug resistance: patient comprehension

HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins

HLA-associated viral mutations are common in human immunodeficiency virus type 1 elite controllers

Hepatitis C testing in Canada: don't leave baby boomers behind.

Higher baseline levels of plasma human immunodeficiency virus type 1 RNA are associated with increased mortality after initiation of triple-drug antiretroviral therapy

Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection

Impact of baseline viral load and adherence on survival of HIV-infected adults with baseline CD4 cell counts ≥ 200 cells/μl

Improved virological outcomes in British Columbia concomitant with decreasing incidence of HIV type 1 drug resistance detection

Increased Prevalence of Controlled Viremia and Decreased Rates of HIV Drug Resistance Among HIV-Positive People Who Use Illicit Drugs During a Community-wide Treatment-as-Prevention Initiative

Increased reporting of detectable plasma HIV-1 RNA levels at the critical threshold of 50 copies per milliliter with the Taqman assay in comparison to the Amplicor assay

Increased resilience to the development of drug resistance with modern boosted protease inhibitor-based highly active antiretroviral therapy

Initiation of antiretroviral therapy at high CD4+ cell counts is associated with positive treatment outcomes

Is nevirapine-based therapy discontinuation in hepatitis C co-infected patients a more important mortality determinant than hypersensitivity: authors' reply

Is there a baseline CD4 cell count that precludes a survival response to modern antiretroviral therapy?

Longitudinal community plasma HIV-1 RNA concentrations and incidence of HIV-1 among injecting drug users: prospective cohort study.

Lower prevalence of drug resistance mutations at first-line virological failure to first-line therapy with atripla vs. tenofovir + emtricitabine/lamivudine + efavirenz administered on a multiple tablet therapy

Magnitude of Virologic Blips Is Associated With a Higher Risk for Virologic Rebound in HIV-Infected Individuals: A Recurrent Events Analysis ⬇️

Mitochondrial DNA somatic mutation burden and heteroplasmy are associated with chronological age, smoking, and HIV infection

Mitochondrial toxicity in the era of HAART: evaluating venous lactate and peripheral blood mitochondrial DNA in HIV-infected patients taking antiretroviral therapy

Mitochondrial:nuclear DNA ratios in peripheral blood cells from human immunodeficiency virus (HIV)-infected patients who received selected HIV antiretroviral drug regimens

Molecular and Clinical Epidemiology of CXCR4‐Using HIV‐1 in a Large Population of Antiretroviral‐Naive Individuals

Near real-time monitoring of HIV transmission hotspots from routine HIV genotyping: an implementation case study

Nucleoside-related mitochondrial toxicity among HIV-infected patients receiving antiretroviral therapy: insights from the evaluation of venous lactic acid and peripheral blood mitochondrial DNA.

Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.

Post-marketing experience with nevirapine extended release (XR) tablets: effectiveness and tolerability in a population-based cohort in British Columbia, Canada

Predicting hospitalization among HIV-infected antiretroviral naïve patients starting HAART: determining clinical markers and exploring social pathways

Predictors of HIV drug-resistance mutations in a large antiretroviral-naive cohort initiating triple antiretroviral therapy

Rates of antiretroviral resistance among HIV-infected patients with and without a history of injection drug use.

Rates of disease progression among human immunodeficiency virus-infected persons initiating multiple-drug rescue therapy

Regional differences in rates of HIV-1 viral load monitoring in Canada: Insights and implications for antiretroviral care in high income countries

Relative effects of antiretroviral therapy and harm reduction initiatives on HIV incidence in British Columbia, Canada, 1996-2013: a modelling study

Risk of viral failure declines with duration of suppression on highly active antiretroviral therapy irrespective of adherence level

Short communication. Association of the CCR5delta32 mutation with clinical response and >5-year survival following initiation of first triple antiretroviral regimen

Tenofovir and emtricitabine resistance among antiretroviral-naive patients in the Canadian Observational Cohort Collaboration: implications for PrEP

The Impact of Adherence on CD4 Cell Count Responses Among HIV-Infected Patients

The case for expanding access to highly active antiretroviral therapy to curb the growth of the HIV epidemic

The combined effect of modern highly active antiretroviral therapy regimens and adherence on mortality over time

The development of an expert system to predict virological response to HIV therapy as part of an online treatment support tool

The development of artificial neural networks to predict virological response to combination HIV therapy.

The impact of clinical, demographic and risk factors on rates of HIV transmission: a population-based phylogenetic analysis in British Columbia, Canada

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

The relationship between resistance and adherence in drug-naive individuals initiating HAART is specific to individual drug classes

Treatment interruption of highly active antiretroviral therapy in patients with nadir CD4 cell counts >200 cells/mm3.

Trends in plasma HIV-RNA suppression and antiretroviral resistance in British Columbia, 1997-2010

Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity

Using baseline CD4 cell count and plasma HIV RNA to guide the initiation of highly active antiretroviral therapy

When to initiate antiretroviral therapy in HIV-1-infected adults: a review for clinicians and patients