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A phase I study of the combination of panitumumab and bevacizumab in KRAS wild-type colorectal cancer patients previously treated with fluoropyrimidine, oxaliplatin, irinotecan and bevacizumab

artículo científico publicado en 2016

ACTN4 gene amplification and actinin-4 protein overexpression drive tumour development and histological progression in a high-grade subset of ovarian clear-cell adenocarcinomas

artículo científico publicado en 2012

Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells

artículo científico publicado en 2017

Actinin-4 expression in ovarian cancer: a novel prognostic indicator independent of clinical stage and histological type

artículo científico publicado en 2007

Actinin-4 gene amplification in ovarian cancer: a candidate oncogene associated with poor patient prognosis and tumor chemoresistance

artículo científico publicado en 2009

Actinin-4 increases cell motility and promotes lymph node metastasis of colorectal cancer

scientific journal article

Actinin-4 protein overexpression as a predictive biomarker in adjuvant chemotherapy for resected lung adenocarcinoma.

artículo científico publicado en 2017

Actinin-4 splice variant - a complementary diagnostic and prognostic marker of pancreatic neuroendocrine neoplasms

artículo científico publicado en 2020

Altered DNA methylation is associated with aberrant stemness gene expression in early‑stage HNSCC

scientific article published on 14 August 2019

Altered Plasma Apolipoprotein Modifications in Patients with Pancreatic Cancer: Protein Characterization and Multi-Institutional Validation ⬇️

artículo científico publicado el 8 de octubre de 2012

Alternative mammalian target of rapamycin (mTOR) signal activation in sorafenib-resistant hepatocellular carcinoma cells revealed by array-based pathway profiling

artículo científico publicado en 2014

Alternative splice variant of actinin-4 in small cell lung cancer

artículo científico publicado en 2004

Apolipoprotein A2 Isoforms in Relation to the Risk of Myocardial Infarction: A Nested Case-Control Analysis in the JPHC Study

scientific article published on 29 August 2020

Beta-catenin interacts with the FUS proto-oncogene product and regulates pre-mRNA splicing.

artículo científico publicado en 2005

Biological significance of actinin-4 in the mechanism of cancer invasion and metastasis

artículo científico publicado en 2012

Biomarker Discovery of Pancreatic and Gastrointestinal Cancer by 2DICAL: 2-Dimensional Image-Converted Analysis of Liquid Chromatography and Mass Spectrometry

artículo científico publicado en 2012

CA19-9 and Apolipoprotein-A2 isoforms as detection markers for pancreatic cancer - a prospective evaluation

artículo científico publicado en 2018

CA19-9 as a therapeutic target in pancreatitis

artículo científico publicado en 2019

Carbonic anhydrase I as a new plasma biomarker for prostate cancer.

artículo científico publicado en 2012

Combined functional genome survey of therapeutic targets for clear cell carcinoma of the kidney

artículo científico publicado en 2011

Combined functional genome survey of therapeutic targets for hepatocellular carcinoma

artículo científico publicado en 2010

Comprehensive characterization of the phosphoproteome of gastric cancer from endoscopic biopsy specimens

artículo científico publicado en 2020

Copy number increase of ACTN4 is a prognostic indicator in salivary gland carcinoma

artículo científico publicado en 2014

Correction: Alternative mammalian target of rapamycin (mTOR) signal activation in sorafenib-resistant hepatocellular carcinoma cells revealed by array-based pathway profiling

scientific article published on 01 January 2020

Distinct gene expression-defined classes of gastrointestinal stromal tumor.

artículo científico publicado en 2008

E-cadherin regulates the association between beta-catenin and actinin-4

artículo científico publicado en 2005

Efficacy of adjuvant chemotherapy for non-small cell lung cancer assessed by metastatic potential associated with ACTN4.

artículo científico publicado en 2016

Expression and gene amplification of actinin-4 in invasive ductal carcinoma of the pancreas

artículo científico publicado en 2008

Functional genome screen for therapeutic targets of osteosarcoma

artículo científico publicado en 2009

Functional interaction of DNA topoisomerase IIalpha with the beta-catenin and T-cell factor-4 complex

artículo científico publicado en 2007

Histological growth pattern of and alpha-actinin-4 expression in thyroid cancer

Identification of 2 serum biomarkers of renal cell carcinoma by surface enhanced laser desorption/ionization mass spectrometry

artículo científico publicado en 2005

Identification of Adipophilin as a Potential Plasma Biomarker for Colorectal Cancer Using Label-Free Quantitative Mass Spectrometry and Protein Microarray ⬇️

artículo científico publicado el 9 de agosto de 2011

Identification of IGFBP2 and IGFBP3 As Compensatory Biomarkers for CA19-9 in Early-Stage Pancreatic Cancer Using a Combination of Antibody-Based and LC-MS/MS-Based Proteomics

artículo científico publicado en 2016

Identification of a predictive biomarker for hematologic toxicities of gemcitabine

artículo científico publicado en 2009

Identification of highly sensitive biomarkers that can aid the early detection of pancreatic cancer using GC/MS/MS-based targeted metabolomics

artículo científico publicado en 2017

Identification of serum biomarkers of chemoradiosensitivity in esophageal cancer via the targeted metabolomics approach

scientific article published on 25 July 2018

Immunohistochemical actinin-4 expression in infiltrating gliomas: association with WHO grade and differentiation ⬇️

artículo científico publicado el 17 de marzo de 2013

Increased susceptibility of Sf1(+/-) mice to azoxymethane-induced colon tumorigenesis

artículo científico

Involvement of splicing factor-1 in beta-catenin/T-cell factor-4-mediated gene transactivation and pre-mRNA splicing.

artículo científico publicado en 2007

Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins

artículo científico publicado en 2013

Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling

artículo científico publicado en 2007

Label-free quantitative proteomics using large peptide data sets generated by nanoflow liquid chromatography and mass spectrometry

artículo científico publicado en 2006

Large-scale quantitative clinical proteomics by label-free liquid chromatography and mass spectrometry.

artículo científico publicado en 2008

Leucine-Rich Alpha-2-Glycoprotein 1 in Serum Is a Possible Biomarker to Predict Response to Preoperative Chemoradiotherapy for Esophageal Cancer

artículo científico publicado en 2019

Live single cell mass spectrometry reveals cancer-specific metabolic profiles of circulating tumor cells

artículo científico publicado en 2019

Mass spectrometry analysis of the native protein complex containing actinin-4 in prostate cancer cells

artículo científico publicado en 2006

Measurement of copy number of ACTN4 to optimize the therapeutic strategy for locally advanced pancreatic cancer

artículo científico publicado en 2018

Metabolomics-based Discovery of Serum Biomarkers to Predict the Side-effects of Neoadjuvant Chemoradiotherapy for Esophageal Squamous Cell Carcinoma

artículo científico publicado en 2019

MicroRNA expression and functional profiles of osteosarcoma

artículo científico publicado en 2014

Monitoring of cancer patients via next-generation sequencing of patient-derived circulating tumor cells and tumor DNA

artículo científico publicado en 2019

Morphological and transcriptional responses of untransformed intestinal epithelial cells to an oncogenic beta-catenin protein

artículo científico publicado en 2005

Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins in biological samples

artículo científico publicado en 2020

O-Glycan-Altered Extracellular Vesicles: A Specific Serum Marker Elevated in Pancreatic Cancer

artículo científico publicado en 2020

Plasma biomarker discovery and validation for colorectal cancer by quantitative shotgun mass spectrometry and protein microarray ⬇️

artículo científico publicado el 28 de diciembre de 2010

Plasma biomarker for detection of early stage pancreatic cancer and risk factors for pancreatic malignancy using antibodies for apolipoprotein-AII isoforms

artículo científico publicado en 2015

Plasma proteomics of pancreatic cancer patients by multi-dimensional liquid chromatography and two-dimensional difference gel electrophoresis (2D-DIGE): up-regulation of leucine-rich alpha-2-glycoprotein in pancreatic cancer

scientific article published on 01 February 2007

Poly(ADP-ribose) polymerase-1 is a component of the oncogenic T-cell factor-4/beta-catenin complex.

artículo científico publicado en 2005

Possible detection of pancreatic cancer by plasma protein profiling

artículo científico publicado en 2005

Possible prediction of chemoradiosensitivity of esophageal cancer by serum protein profiling.

artículo científico publicado en 2005

Potential usefulness of apolipoprotein A2 isoforms for screening and risk stratification of pancreatic cancer

artículo científico publicado en 2016

Prognostic impact of ACTN4 gene copy number alteration in hormone receptor-positive, HER2-negative, node-negative invasive breast carcinoma

scientific article published on 08 April 2020

Prognostic significance of tissue factor in pancreatic ductal adenocarcinoma

artículo científico publicado en 2005

Prolyl 4-hydroxylation of alpha-fibrinogen: a novel protein modification revealed by plasma proteomics

artículo científico publicado en 2009

Prospective Study Using Plasma Apolipoprotein A2-Isoforms to Screen for High-Risk Status of Pancreatic Cancer

scientific article published on 14 September 2020

Prospects for Comprehensive Analyses of Circulating Tumor Cells in Tumor Biology

scientific article published on 01 May 2020

Proteomic Approaches to the Discovery of Cancer Biomarkers for Early Detection and Personalized Medicine ⬇️

artículo científico publicado el 16 de diciembre de 2012

Quantitative proteomics using formalin-fixed paraffin-embedded tissues of oral squamous cell carcinoma

artículo científico publicado en 2009

Rab13 Small G Protein and Junctional Rab13-binding Protein (JRAB) Orchestrate Actin Cytoskeletal Organization during Epithelial Junctional Development ⬇️

artículo científico publicado el 24 de octubre de 2012

Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L2

artículo científico publicado en 2010

Reduced argininosuccinate synthetase is a predictive biomarker for the development of pulmonary metastasis in patients with osteosarcoma

artículo científico publicado en 2010

Reduced plasma level of CXC chemokine ligand 7 in patients with pancreatic cancer

scientific article published on 08 December 2010

Regulation of Wnt signaling by the nuclear pore complex

artículo científico publicado en 2008

SOX10 is a novel marker of acinus and intercalated duct differentiation in salivary gland tumors: a clue to the histogenesis for tumor diagnosis

artículo científico publicado en 2013

Serum albumin-associated peptides of patients with uterine endometrial cancer

artículo científico publicado en 2007

Serum apolipoprotein A2 isoforms in autoimmune pancreatitis

artículo científico publicado en 2018

Serum level of octanoic acid predicts the efficacy of chemotherapy for colorectal cancer

scientific article published on 19 November 2018

Soluble interleukin‐6 receptor is a serum biomarker for the response of esophageal carcinoma to neoadjuvant chemoradiotherapy ⬇️

artículo científico publicado el 13 de junio de 2013

Survival prediction for pancreatic cancer patients receiving gemcitabine treatment

artículo científico publicado en 2010

Temporal dynamics from phosphoproteomics using endoscopic biopsy specimens provides new therapeutic targets in stage IV gastric cancer

artículo científico publicado en 2022

The alternatively spliced actinin-4 variant as a prognostic marker for metastasis in small-cell lung cancer

artículo científico publicado en 2015

The biological role of actinin-4 (ACTN4) in malignant phenotypes of cancer

artículo científico publicado en 2015

The peripheral immune status of granulocytic myeloid-derived suppressor cells correlates the survival in advanced gastric cancer patients receiving cisplatin-based chemotherapy

artículo científico publicado en 2017

Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth

artículo científico publicado en 2010

Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation

artículo científico publicado en 2010

Trends in biomarker discoveries for the early detection and risk stratification of pancreatic cancer using omics studies

scientific article published on 17 July 2019

Underexpression of α-1-microglobulin/bikunin precursor predicts a poor prognosis in oral squamous cell carcinoma

artículo científico publicado en 2018

Use of Biomarkers and Imaging for Early Detection of Pancreatic Cancer

scientific article published on 19 July 2020

Use of quantitative shotgun proteomics to identify fibronectin 1 as a potential plasma biomarker for clear cell carcinoma of the kidney

artículo científico publicado el 8 de junio de 2012

Usefulness of serum protein profiling for prediction of preoperative chemoradiosensitivity of esophageal cancer

artículo científico publicado en 2007

[Early detection of pancreatic cancer by novel proteomic technique].

artículo científico publicado en 2006

β-catenin inhibits promyelocytic leukemia protein tumor suppressor function in colorectal cancer cells

artículo científico publicado en 2012

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