Lista de obras -

A deep neural network to assess spontaneous pain from mouse facial expressions

artículo científico publicado en 2018

A high throughput assay to identify small molecule modulators of prostatic acid phosphatase

artículo científico publicado en 2009

A steroid-conjugated contrast agent for magnetic resonance imaging of cell signaling

artículo científico publicado en 2005

AMP Is an Adenosine A1 Receptor Agonist ⬇️

artículo científico publicado el 3 de enero de 2012

Accurate and High Throughput Cell Segmentation Method for Mouse Brain Nuclei Using Cascaded Convolutional Neural Network

scholarly article by Qian Wang et al published 2017 in Lecture Notes in Computer Science

An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A.

artículo científico publicado en 2015

Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes

artículo científico publicado en 2011

Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family

artículo científico publicado en 2003

Biological constraints limit the use of rapamycin-inducible FKBP12-Inp54p for depleting PIP2 in dorsal root ganglia neurons

artículo científico publicado en 2013

CGRPα-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch ⬇️

artículo científico publicado el 1 de enero de 2012

Cas9 gene therapy for Angelman syndrome traps Ube3a-ATS long non-coding RNA

artículo científico publicado en 2020

Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life

artículo científico publicado en 2020

Choice of vehicle affects pyraclostrobin toxicity in mice

scientific article published on 23 November 2018

Content and Performance of the MiniMUGA Genotyping Array, a New Tool To Improve Rigor and Reproducibility in Mouse Research

scientific article published on 16 October 2020

Controlling litter effects to enhance rigor and reproducibility with rodent models of neurodevelopmental disorders

Deletion of ENTPD3 does not impair nucleotide hydrolysis in primary somatosensory neurons or spinal cord

artículo científico publicado en 2014

Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration

scientific article published on 23 April 2020

Development of a High-Throughput Screening Assay to Identify Inhibitors of the Lipid Kinase PIP5K1C

artículo científico publicado en 2014

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

artículo científico publicado en 2009

Ecto-5'-nucleotidase (CD73) inhibits nociception by hydrolyzing AMP to adenosine in nociceptive circuits

artículo científico publicado en 2010

Emerging Roles for Ectonucleotidases in Pain-Sensing Neurons ⬇️

artículo científico publicado el 1 de enero de 2011

Enhanced Nociception in Angelman Syndrome Model Mice

artículo científico publicado en 2017

Enhanced behavioral responses to cold stimuli following CGRPα sensory neuron ablation are dependent on TRPM8.

artículo científico publicado en 2014

Enhanced histamine-induced itch in diacylglycerol kinase iota knockout mice

artículo científico publicado en 2019

Fiber-coupled light-emitting diode for localized photostimulation of neurons expressing channelrhodopsin-2.

artículo científico publicado en 2007

GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility

artículo científico publicado en 2016

Gene length matters in neurons

artículo científico publicado en 2015

High-throughput screen identifies cyclic nucleotide analogs that inhibit prostatic acid phosphatase

artículo científico publicado en 2012

High-throughput screening and classification of chemicals and their effects on neuronal gene expression using RASL-seq

article

Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration.

artículo científico publicado en 2016

Improving pain assessment in mice and rats with advanced videography and computational approaches

artículo científico publicado en 2020

Lipid kinases as therapeutic targets for chronic pain

artículo científico publicado en 2015

Mania- and anxiety-like behavior and impaired maternal care in female diacylglycerol kinase eta and iota double knockout mice

artículo científico publicado en 2019

Maternal Ube3a Loss Disrupts Sleep Homeostasis But Leaves Circadian Rhythmicity Largely Intact.

artículo científico publicado en 2015

Mechanisms of compartmentalized expression of Mrg class G-protein-coupled sensory receptors

artículo científico publicado en 2008

Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch

artículo científico publicado en 2007

Mrgprd enhances excitability in specific populations of cutaneous murine polymodal nociceptors

scientific article published on July 2009

Mrgprd-expressing polymodal nociceptive neurons innervate most known classes of substantia gelatinosa neurons

artículo científico publicado en 2009

Needling adenosine receptors for pain relief

artículo científico publicado en 2010

Nonpeptidergic circuits feel your pain

artículo científico publicado en 2005

Optimizing Promoters for Recombinant Adeno-Associated Virus-Mediated Gene Expression in the Peripheral and Central Nervous System Using Self-Complementary Vectors ⬇️

artículo científico publicado el 1 de junio de 2011

Orally Active Adenosine A1 Receptor Agonists with Antinociceptive Effects in Mice ⬇️

artículo científico publicado el 16 de julio de 2012

Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway

artículo científico publicado en 2002

Overexpression of diacylglycerol kinase η enhances Gαq-coupled G protein-coupled receptor signaling

artículo científico publicado en 2014

PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosine

artículo científico publicado en 2011

PAPupuncture has localized and long-lasting antinociceptive effects in mouse models of acute and chronic pain

artículo científico publicado en 2012

Pain-relieving prospects for adenosine receptors and ectonucleotidases

artículo científico publicado en 2011

Peptidergic CGRPα Primary Sensory Neurons Encode Heat and Itch and Tonically Suppress Sensitivity to Cold ⬇️

artículo científico publicado el 21 de marzo de 2013

Photochemical activation of TRPA1 channels in neurons and animals

artículo científico publicado en 2013

Prenatal treatment path for angelman syndrome and other neurodevelopmental disorders

artículo científico publicado en 2019

Prostatic Acid Phosphatase Is Required for the Antinociceptive Effects of Thiamine and Benfotiamine ⬇️

artículo científico publicado el 31 de octubre de 2012

Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine

artículo científico publicado en 2008

Prostatic acid phosphatase is expressed in peptidergic and nonpeptidergic nociceptive neurons of mice and rats

artículo científico publicado en 2010

Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phosphatidylinositol 4,5-bisphosphate

artículo científico publicado en 2010

Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation

artículo científico publicado en 2010

Recombinant mouse PAP has pH-dependent ectonucleotidase activity and acts through A(1)-adenosine receptors to mediate antinociception

artículo científico publicado en 2009

Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector

scientific journal article

Secretion and N-Linked Glycosylation Are Required for Prostatic Acid Phosphatase Catalytic and Antinociceptive Activity ⬇️

artículo científico publicado el 28 de febrero de 2012

Sex, drugs and pain control

artículo científico publicado en 2015

Single-cell transcriptomic analysis of mouse neocortical development

artículo científico publicado en 2019

Snx14 regulates neuronal excitability, promotes synaptic transmission, and is imprinted in the brain of mice

artículo científico publicado en 2014

Strobilurin fungicides in house dust: is wallboard a source?

artículo científico publicado en 2019

The F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently.

artículo científico publicado en 2012

The Troubled Touch of Autism.

artículo científico publicado en 2016

The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome

artículo científico publicado en 2017

The lipid kinase PIP5K1C regulates pain signaling and sensitization

artículo científico publicado en 2014

Tissue-nonspecific alkaline phosphatase acts redundantly with PAP and NT5E to generate adenosine in the dorsal spinal cord.

artículo científico publicado en 2013

Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd

artículo científico publicado en 2005

Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.

artículo científico publicado en 2016

Topoisomerase 1 inhibition reversibly impairs synaptic function.

artículo científico publicado en 2014

Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons ⬇️

artículo científico publicado el 21 de diciembre de 2011

Topoisomerases facilitate transcription of long genes linked to autism

artículo científico publicado en 2013

Zylka et al. reply

artículo científico publicado en 2014

[EXPRESS] Conditional deletion of Pip5k1c in sensory ganglia and effects on nociception and inflammatory sensitization

artículo científico publicado en 2017

lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA

scientific article published on 27 June 2019

scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy

artículo científico publicado en 2019

Lista de obras de

A deep neural network to assess spontaneous pain from mouse facial expressions

A high throughput assay to identify small molecule modulators of prostatic acid phosphatase

A steroid-conjugated contrast agent for magnetic resonance imaging of cell signaling

AMP Is an Adenosine A1 Receptor Agonist ⬇️

Accurate and High Throughput Cell Segmentation Method for Mouse Brain Nuclei Using Cascaded Convolutional Neural Network

An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A.

Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes

Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family

Biological constraints limit the use of rapamycin-inducible FKBP12-Inp54p for depleting PIP2 in dorsal root ganglia neurons

CGRPα-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch ⬇️

Cas9 gene therapy for Angelman syndrome traps Ube3a-ATS long non-coding RNA

Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life

Choice of vehicle affects pyraclostrobin toxicity in mice

Content and Performance of the MiniMUGA Genotyping Array, a New Tool To Improve Rigor and Reproducibility in Mouse Research

Controlling litter effects to enhance rigor and reproducibility with rodent models of neurodevelopmental disorders

Deletion of ENTPD3 does not impair nucleotide hydrolysis in primary somatosensory neurons or spinal cord

Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration

Development of a High-Throughput Screening Assay to Identify Inhibitors of the Lipid Kinase PIP5K1C

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

Ecto-5'-nucleotidase (CD73) inhibits nociception by hydrolyzing AMP to adenosine in nociceptive circuits

Emerging Roles for Ectonucleotidases in Pain-Sensing Neurons ⬇️

Enhanced Nociception in Angelman Syndrome Model Mice

Enhanced behavioral responses to cold stimuli following CGRPα sensory neuron ablation are dependent on TRPM8.

Enhanced histamine-induced itch in diacylglycerol kinase iota knockout mice

Fiber-coupled light-emitting diode for localized photostimulation of neurons expressing channelrhodopsin-2.

GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility

Gene length matters in neurons

High-throughput screen identifies cyclic nucleotide analogs that inhibit prostatic acid phosphatase

High-throughput screening and classification of chemicals and their effects on neuronal gene expression using RASL-seq

Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration.

Improving pain assessment in mice and rats with advanced videography and computational approaches

Lipid kinases as therapeutic targets for chronic pain

Mania- and anxiety-like behavior and impaired maternal care in female diacylglycerol kinase eta and iota double knockout mice

Maternal Ube3a Loss Disrupts Sleep Homeostasis But Leaves Circadian Rhythmicity Largely Intact.

Mechanisms of compartmentalized expression of Mrg class G-protein-coupled sensory receptors

Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch

Mrgprd enhances excitability in specific populations of cutaneous murine polymodal nociceptors

Mrgprd-expressing polymodal nociceptive neurons innervate most known classes of substantia gelatinosa neurons

Needling adenosine receptors for pain relief

Nonpeptidergic circuits feel your pain

Optimizing Promoters for Recombinant Adeno-Associated Virus-Mediated Gene Expression in the Peripheral and Central Nervous System Using Self-Complementary Vectors ⬇️

Orally Active Adenosine A1 Receptor Agonists with Antinociceptive Effects in Mice ⬇️

Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway

Overexpression of diacylglycerol kinase η enhances Gαq-coupled G protein-coupled receptor signaling

PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosine

PAPupuncture has localized and long-lasting antinociceptive effects in mouse models of acute and chronic pain

Pain-relieving prospects for adenosine receptors and ectonucleotidases

Peptidergic CGRPα Primary Sensory Neurons Encode Heat and Itch and Tonically Suppress Sensitivity to Cold ⬇️

Photochemical activation of TRPA1 channels in neurons and animals

Prenatal treatment path for angelman syndrome and other neurodevelopmental disorders

Prostatic Acid Phosphatase Is Required for the Antinociceptive Effects of Thiamine and Benfotiamine ⬇️

Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine

Prostatic acid phosphatase is expressed in peptidergic and nonpeptidergic nociceptive neurons of mice and rats

Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phosphatidylinositol 4,5-bisphosphate

Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation

Recombinant mouse PAP has pH-dependent ectonucleotidase activity and acts through A(1)-adenosine receptors to mediate antinociception

Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector

Secretion and N-Linked Glycosylation Are Required for Prostatic Acid Phosphatase Catalytic and Antinociceptive Activity ⬇️

Sex, drugs and pain control

Single-cell transcriptomic analysis of mouse neocortical development

Snx14 regulates neuronal excitability, promotes synaptic transmission, and is imprinted in the brain of mice

Strobilurin fungicides in house dust: is wallboard a source?

The F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently.

The Troubled Touch of Autism.

The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome

The lipid kinase PIP5K1C regulates pain signaling and sensitization

Tissue-nonspecific alkaline phosphatase acts redundantly with PAP and NT5E to generate adenosine in the dorsal spinal cord.

Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd

Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.

Topoisomerase 1 inhibition reversibly impairs synaptic function.

Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons ⬇️

Topoisomerases facilitate transcription of long genes linked to autism

Zylka et al. reply

[EXPRESS] Conditional deletion of Pip5k1c in sensory ganglia and effects on nociception and inflammatory sensitization

lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA

scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy