Lista de obras - Oscar Harari - Dominio Público Uruguay

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

artículo científico publicado en 2017

A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks

scientific journal article

A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

artículo científico publicado en 2019

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

artículo científico publicado en 2019

Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease

artículo científico publicado en 2017

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

article

Ascertaining perturbations in microglial expression profiles using single‐nuclei RNA‐seq from human brains

artículo científico publicado en 2020

Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline.

artículo científico publicado en 2018

CCL23: A Chemokine Associated with Progression from Mild Cognitive Impairment to Alzheimer's Disease

scientific article published on 01 January 2020

CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN.

artículo científico publicado en 2017

Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry

artículo científico publicado en 2013

Coding variants in TREM2 increase risk for Alzheimer's disease

artículo científico publicado en 2014

Correction to: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience

artículo científico publicado en 2018

Correction to: Overlapping genetic architecture between Parkinson disease and melanoma

scientific article published on 14 March 2020

Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease.

artículo científico publicado en 2018

Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD Through Multiple Phenotypes

artículo científico publicado en 2020

Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease

artículo científico publicado en 2020

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

artículo científico publicado en 2013

Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure.

artículo científico publicado en 2018

Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers

artículo científico publicado en 2017

Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation

artículo científico publicado en 2014

Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families

scientific journal article

Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders

artículo científico publicado en 2021

Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP

artículo científico publicado en 2018

Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience

artículo científico publicado en 2017

Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy

artículo científico publicado en 2021

Missense variant in TREML2 protects against Alzheimer's disease

scientific article published on 21 December 2013

Multi-ancestry genetic study in 5,876 patients identifies an association between excitotoxic genes and early outcomes after acute ischemic stroke

artículo científico publicado en 2020

Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains

artículo científico publicado en 2022

Overlapping genetic architecture between Parkinson disease and melanoma

scientific article published on 16 December 2019

Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels.

artículo científico publicado en 2017

Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways

artículo científico publicado en 2012

Phosphorylated tau-Aβ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer's disease in multiplex immunoassay panels of cerebrospinal fluid

artículo científico publicado en 2014

Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms.

artículo científico publicado en 2017

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

artículo científico publicado en 2014

Single‐nuclei RNA‐seq of brains carriers of high‐risk variants and Mendelian mutations

artículo científico publicado en 2020

TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis

artículo científico publicado en 2020

TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers

artículo científico publicado en 2019

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk

scientific article published on 01 August 2019

The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion

scientific article published on 27 August 2019

Use of a predictive model derived from in vivo endophenotype measurements to demonstrate associations with a complex locus, CYP2A6.

artículo científico publicado en 2012

Lista de obras de Oscar Harari

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks

A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

Ascertaining perturbations in microglial expression profiles using single‐nuclei RNA‐seq from human brains

Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline.

CCL23: A Chemokine Associated with Progression from Mild Cognitive Impairment to Alzheimer's Disease

CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN.

Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry

Coding variants in TREM2 increase risk for Alzheimer's disease

Correction to: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience

Correction to: Overlapping genetic architecture between Parkinson disease and melanoma

Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease.

Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD Through Multiple Phenotypes

Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure.

Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers

Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation

Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families

Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders

Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP

Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience

Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy

Missense variant in TREML2 protects against Alzheimer's disease

Multi-ancestry genetic study in 5,876 patients identifies an association between excitotoxic genes and early outcomes after acute ischemic stroke

Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains

Overlapping genetic architecture between Parkinson disease and melanoma

Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels.

Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways

Phosphorylated tau-Aβ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer's disease in multiplex immunoassay panels of cerebrospinal fluid

Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms.

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

Single‐nuclei RNA‐seq of brains carriers of high‐risk variants and Mendelian mutations

TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis

TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk

The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion

Use of a predictive model derived from in vivo endophenotype measurements to demonstrate associations with a complex locus, CYP2A6.