Lista de obras -

A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

artículo científico publicado en 2022

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

artículo científico publicado en 2017

A common missense variant of LILRB5 is associated with statin intolerance and myalgia.

artículo científico publicado en 2017

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

artículo científico publicado en 2007

A common variant of HMGA2 is associated with adult and childhood height in the general population

artículo científico publicado en 2007

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes

article

A paucimorphic variant in the HMG-CoA reductase gene is associated with lipid-lowering response to statin treatment in diabetes: a GoDARTS study.

artículo científico publicado en 2008

A single nucleotide polymorphism on exon-4 of the gene encoding PPARdelta is associated with reduced height in adults and children.

artículo científico publicado en 2009

Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data

artículo científico publicado en 2008

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

artículo científico publicado en 2017

Apolipoprotein E genotypes are associated with lipid-lowering responses to statin treatment in diabetes: a Go-DARTS study.

artículo científico publicado en 2008

Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk

artículo científico publicado en 2008

Association of common variation in the PPARA gene with incident myocardial infarction in individuals with type 2 diabetes: a Go-DARTS study

artículo científico publicado en 2005

Both high and low HbA1c predict incident heart failure in type 2 diabetes mellitus

artículo científico publicado en 2015

CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia

artículo científico

Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe).

artículo científico publicado en 2011

Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study

artículo científico publicado en 2004

Clinical and genetic determinants of progression of type 2 diabetes: a DIRECT study

artículo científico publicado en 2013

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

artículo científico publicado en 2016

Cohort Profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness.

artículo científico publicado en 2012

Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS).

artículo científico publicado en 2017

Combined effect of inflammatory gene polymorphisms and the risk of ischemic stroke in a prospective cohort of subjects with type 2 diabetes: a Go-DARTS study.

artículo científico publicado en 2010

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants in WFS1 confer risk of type 2 diabetes

artículo científico publicado en 2007

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

artículo científico publicado en 2010

Common variants near MC4R are associated with fat mass, weight and risk of obesity

artículo científico publicado en 2008

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

artículo científico publicado en 2008

Copy number variation in the human Y chromosome in the UK population

artículo científico publicado en 2015

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Discovery of novel heart rate-associated loci using the Exome Chip

artículo científico publicado en 2017

Effect of Metformin on mortality in patients with heart failure and type 2 diabetes mellitus

artículo científico publicado en 2010

Effect of socioeconomic status on mortality among people with type 2 diabetes: a study from the Scottish Diabetes Research Network Epidemiology Group

artículo científico publicado en 2011

Epidemiology and Heritability of Major Depressive Disorder, Stratified by Age of Onset, Sex, and Illness Course in Generation Scotland: Scottish Family Health Study (GS:SFHS)

artículo científico publicado en 2015

Erratum. Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Diabetes 2019;68:441-456

scientific article published on 27 April 2020

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2018

Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008-2010

artículo científico publicado en 2015

GENETIC VARIANTS PREDICTING LEFT VENTRICULAR HYPERTROPHY IN A DIABETIC POPULATION

Generation Scotland: the Scottish Family Health Study; a new resource for researching genes and heritability

artículo científico publicado en 2006

Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus

artículo científico publicado en 2020

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

artículo científico publicado en 2009

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

artículo científico publicado en 2015

Genetic loci for retinal arteriolar microcirculation

artículo científico publicado en 2013

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants predicting left ventricular hypertrophy in a diabetic population: a Go-DARTS study including meta-analysis.

artículo científico publicado en 2013

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic variation in Hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression

artículo científico publicado en 2012

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

artículo científico publicado en 2011

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide association study identifies five loci associated with lung function

artículo científico publicado en 2010

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Glycemic exposure and blood pressure influencing progression and remission of diabetic retinopathy: a longitudinal cohort study in GoDARTS.

artículo científico publicado en 2013

Haplotype analysis of the PPARgamma Pro12Ala and C1431T variants reveals opposing associations with body weight.

artículo científico publicado en 2002

Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis

artículo científico publicado en 2014

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

artículo científico publicado en 2015

Increased cardiovascular morbidity and mortality in type 2 diabetes is associated with the glutathione S transferase theta-null genotype: a Go-DARTS study

artículo científico publicado en 2005

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q

artículo científico publicado en 2009

Lp-PLA2 activity is associated with increased risk of diabetic retinopathy: a longitudinal disease progression study

scientific article published on 06 April 2018

Male preponderance in early diagnosed type 2 diabetes is associated with the ARE insertion/deletion polymorphism in the PPP1R3A locus

artículo científico publicado en 2003

Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance

artículo científico publicado en 2011

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

artículo científico publicado en 2008

Mortality and hospitalization in patients after amputation: a comparison between patients with and without diabetes

artículo científico publicado en 2006

Mosaic structural variation in children with developmental disorders

artículo científico publicado en 2015

Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control

scientific article published on 28 November 2018

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant

artículo científico publicado en 2012

Peroxisome proliferator-activated receptor-delta genotype influences metabolic phenotype and may influence lipid response to statin therapy in humans: a genetics of diabetes audit and research Tayside study.

artículo científico publicado en 2010

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

artículo científico publicado en 2014

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Reduced incidence of lower-extremity amputations in people with diabetes in Scotland: a nationwide study

artículo científico publicado en 2012

Reduced-function SLC22A1 polymorphisms encoding organic cation transporter 1 and glycemic response to metformin: a GoDARTS study

artículo científico publicado en 2009

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

artículo científico publicado en 2007

Risk of cardiovascular disease and total mortality in adults with type 1 diabetes: Scottish registry linkage study

artículo científico publicado en 2012

Robust association of the LPA locus with low-density lipoprotein cholesterol lowering response to statin treatment in a meta-analysis of 30 467 individuals from both randomized control trials and observational studies and association with [...]

artículo científico publicado en 2013

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

scientific journal article

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2017

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease

artículo científico publicado en 2015

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

artículo científico publicado en 2012

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

artículo científico publicado en 2017

Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study

artículo científico publicado en 2014

The Common p.R114W HNF4A Mutation Causes a Distinct Clinical Subtype of Monogenic Diabetes

artículo científico publicado en 2016

The FTO gene is associated with an atherogenic lipid profile and myocardial infarction in patients with type 2 diabetes: a Genetics of Diabetes Audit and Research Study in Tayside Scotland (Go-DARTS) study

artículo científico publicado en 2009

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

artículo científico publicado en 2013

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

artículo científico publicado en 2010

Underlying genetic models of inheritance in established type 2 diabetes associations

artículo científico publicado en 2009

Using Web Technology to Support Population-Based Diabetes Care ⬇️

artículo científico publicado el 1 de mayo de 2011

Variants in MTNR1B influence fasting glucose levels

artículo científico publicado en 2008

Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study

artículo científico publicado en 2007

Lista de obras de

A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

A common missense variant of LILRB5 is associated with statin intolerance and myalgia.

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

A common variant of HMGA2 is associated with adult and childhood height in the general population

A genome-wide association search for type 2 diabetes genes in African Americans

A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes

A paucimorphic variant in the HMG-CoA reductase gene is associated with lipid-lowering response to statin treatment in diabetes: a GoDARTS study.

A single nucleotide polymorphism on exon-4 of the gene encoding PPARdelta is associated with reduced height in adults and children.

Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Apolipoprotein E genotypes are associated with lipid-lowering responses to statin treatment in diabetes: a Go-DARTS study.

Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk

Association of common variation in the PPARA gene with incident myocardial infarction in individuals with type 2 diabetes: a Go-DARTS study

Both high and low HbA1c predict incident heart failure in type 2 diabetes mellitus

CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia

Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe).

Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study

Clinical and genetic determinants of progression of type 2 diabetes: a DIRECT study

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

Cohort Profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness.

Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS).

Combined effect of inflammatory gene polymorphisms and the risk of ischemic stroke in a prospective cohort of subjects with type 2 diabetes: a Go-DARTS study.

Common variants associated with plasma triglycerides and risk for coronary artery disease

Common variants in WFS1 confer risk of type 2 diabetes

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

Common variants near MC4R are associated with fat mass, weight and risk of obesity

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

Copy number variation in the human Y chromosome in the UK population

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

Defining the role of common variation in the genomic and biological architecture of adult human height

Directional dominance on stature and cognition in diverse human populations

Discovery and refinement of loci associated with lipid levels

Discovery of novel heart rate-associated loci using the Exome Chip

Effect of Metformin on mortality in patients with heart failure and type 2 diabetes mellitus

Effect of socioeconomic status on mortality among people with type 2 diabetes: a study from the Scottish Diabetes Research Network Epidemiology Group

Epidemiology and Heritability of Major Depressive Disorder, Stratified by Age of Onset, Sex, and Illness Course in Generation Scotland: Scottish Family Health Study (GS:SFHS)

Erratum. Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Diabetes 2019;68:441-456

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008-2010

GENETIC VARIANTS PREDICTING LEFT VENTRICULAR HYPERTROPHY IN A DIABETIC POPULATION

Generation Scotland: the Scottish Family Health Study; a new resource for researching genes and heritability

Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Genetic loci for retinal arteriolar microcirculation

Genetic studies of body mass index yield new insights for obesity biology

Genetic variants predicting left ventricular hypertrophy in a diabetic population: a Go-DARTS study including meta-analysis.

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

Genetic variation in Hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

Genome-wide association study identifies five loci associated with lung function

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Glycemic exposure and blood pressure influencing progression and remission of diabetic retinopathy: a longitudinal cohort study in GoDARTS.

Haplotype analysis of the PPARgamma Pro12Ala and C1431T variants reveals opposing associations with body weight.

Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

Increased cardiovascular morbidity and mortality in type 2 diabetes is associated with the glutathione S transferase theta-null genotype: a Go-DARTS study

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Large-scale association analysis identifies new risk loci for coronary artery disease

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q

Lp-PLA2 activity is associated with increased risk of diabetic retinopathy: a longitudinal disease progression study

Male preponderance in early diagnosed type 2 diabetes is associated with the ARE insertion/deletion polymorphism in the PPP1R3A locus

Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

Mortality and hospitalization in patients after amputation: a comparison between patients with and without diabetes

Mosaic structural variation in children with developmental disorders

Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

New genetic loci link adipose and insulin biology to body fat distribution

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals