Lista de obras -

A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertility

artículo científico publicado en 2011

A systematic analysis of the suitability of preimplantation genetic diagnosis for mitochondrial diseases in a heteroplasmic mitochondrial mouse model.

artículo científico publicado en 2014

Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells

artículo científico publicado en 2021

Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells

artículo científico publicado en 2015

Application Of Small Molecules Favoring Naïve Pluripotency during Human Embryonic Stem Cell Derivation

artículo científico publicado en 2015

Assessing the impact of minimizing arginine conversion in fully defined SILAC culture medium in human embryonic stem cells

artículo científico publicado en 2016

Assessment of nuclear transfer techniques to prevent the transmission of heritable mitochondrial disorders without compromising embryonic development competence in mice

artículo científico publicado en 2014

Assessment of the calcium releasing machinery in oocytes that failed to fertilize after conventional ICSI and assisted oocyte activation

scientific article published on 23 December 2018

Assisted oocyte activation following ICSI fertilization failure

artículo científico

Assisted oocyte activation significantly increases fertilization and pregnancy outcome in patients with low and total failed fertilization after intracytoplasmic sperm injection: a 17-year retrospective study

scientific article published on 24 May 2019

Bta-miR-10b Secreted by Bovine Embryos Negatively Impacts Preimplantation Embryo Quality

artículo científico publicado en 2019

CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells

artículo científico publicado en 2017

Cellular Heterogeneity in the Level of mtDNA Heteroplasmy in Mouse Embryonic Stem Cells.

artículo científico publicado en 2015

Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile man by use of minisequencing of individual sperm and expression in somatic cells

artículo científico publicado en 2012

Chromosomal mosaicism in human blastocysts: the ultimate diagnostic dilemma

artículo científico publicado en 2020

Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background.

artículo científico publicado en 2018

Contemporary pharmacogenetic assays in view of the PharmGKB database

scientific article published on 18 March 2019

Culture conditions affect Ca2+ release in artificially activated mouse and human oocytes

artículo científico publicado en 2018

Culture medium preferences of pre-implantation cloned mouse embryos

artículo científico publicado en 2006

Derivation of human embryonic stem cells using a post-inner cell mass intermediate

artículo científico publicado en 2013

Detailed method description for noninvasive monitoring of differentiation status of human embryonic stem cells

artículo científico publicado en 2014

Developmental competence of parthenogenetic mouse and human embryos after chemical or electrical activation ⬇️

artículo científico publicado el 3 de noviembre de 2010

Diagnosis and Treatment of Male Infertility-Related Fertilization Failure

artículo científico publicado en 2020

Differential apoptotic staining of mammalian blastocysts based on double immunofluorescent CDX2 and active caspase-3 staining

artículo científico publicado en 2011

Effect of two assisted oocyte activation protocols used to overcome fertilization failure on the activation potential and calcium releasing pattern.

artículo científico publicado en 2015

Efficiency of assisted oocyte activation as a solution for failed intracytoplasmic sperm injection

artículo científico publicado en 2008

Erratum to: PLCζ disruption with complete fertilization failure in normozoospermia

artículo científico publicado en 2015

Erratum. Chromosomal mosaicism in human blastocysts: the ultimate diagnostic dilemma

artículo científico publicado en 2020

Establishment and Characterization of Naïve Pluripotency in Human Embryonic Stem Cells.

artículo científico publicado en 2016

Exogenous supplementation of Activin A enhances germ cell differentiation of human embryonic stem cells.

artículo científico publicado en 2015

Globozoospermia is mainly due to DPY19L2 deletion via non-allelic homologous recombination involving two recombination hotspots.

artículo científico publicado en 2012

Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts

artículo científico publicado en 2022

Human blastocyst outgrowths recapitulate primordial germ cell specification events

artículo científico publicado en 2019

Human embryo research in Belgium: an overview.

artículo científico publicado en 2017

Human germline gene editing. Recommendations of ESHG and ESHRE

scientific article published on 12 January 2018

Human germline gene editing: Recommendations of ESHG and ESHRE.

artículo científico publicado en 2018

Identification of histone H3 clipping activity in human embryonic stem cells

artículo científico publicado en 2014

Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential

artículo científico publicado en 2013

Inhibition of transforming growth factor β signaling promotes epiblast formation in mouse embryos

artículo científico publicado en 2014

Language development of children born following intracytoplasmic sperm injection (ICSI) combined with assisted oocyte activation (AOA).

artículo científico publicado en 2014

Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes

artículo científico publicado en 2011

Metabolic plasticity complements the unique nature and demands of distinct pluripotency states

artículo científico publicado en 2017

Modelling human embryogenesis: embryo-like structures spark ethical and policy debate

artículo científico publicado en 2020

Mutation-free baby born from a mitochondrial encephalopathy, lactic acidosis and stroke-like syndrome carrier after blastocyst trophectoderm preimplantation genetic diagnosis.

artículo científico publicado en 2014

Neonatal and neurodevelopmental outcome of children aged 3-10 years born following assisted oocyte activation

artículo científico publicado en 2013

Novel reproductive technologies to prevent mitochondrial disease

artículo científico publicado en 2017

PLCζ disruption with complete fertilization failure in normozoospermia

artículo científico publicado en 2015

PLCζ is the physiological trigger of the Ca2+ oscillations that induce embryogenesis in mammals but conception can occur in its absence

artículo científico publicado en 2017

Pan-cancer pharmacogenetics: targeted sequencing panels or exome sequencing?

artículo científico publicado en 2020

Patients with a high proportion of immature and meiotically resistant oocytes experience defective nuclear oocyte maturation patterns and impaired pregnancy outcomes.

artículo científico publicado en 2018

Polar body mutation load analysis in a patient with A3243G tRNALeu(UUR) point mutation

artículo científico publicado en 2011

Poor correlation between polar bodies and blastomere mutation load in a patient with m.3243A>G tRNALeu(UUR) point mutation.

artículo científico publicado en 2012

Preimplantation genetic diagnosis for chromosomal rearrangements with the use of array comparative genomic hybridization at the blastocyst stage

artículo científico publicado en 2016

Procaine Induces Cytokinesis in Horse Oocytes via a pH-Dependent Mechanism

artículo científico publicado en 2015

Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions

artículo científico publicado en 2020

Reference loci for RT-qPCR analysis of differentiating human embryonic stem cells

artículo científico publicado en 2013

Responsible innovation in human germline gene editing. Background document to the recommendations of ESHG and ESHRE

scientific article published on 12 January 2018

Responsible innovation in human germline gene editing: Background document to the recommendations of ESHG and ESHRE.

artículo científico publicado en 2018

Robust protocol for feeder-free adaptation of cryopreserved human pluripotent stem cells

artículo científico publicado en 2019

Serial pronuclear transfer increases the developmental potential of in vitro-matured oocytes in mouse cloning

artículo científico publicado en 2002

Shallow whole genome sequencing is well suited for the detection of chromosomal aberrations in human blastocysts

artículo científico publicado en 2015

Single Ca (2+) transients versus oscillatory Ca(2+) signalling: limitations and benefits

artículo científico publicado en 2017

Slow controlled-rate freezing of human in vitro matured oocytes: effects on maturation rate and kinetics and parthenogenetic activation

artículo científico publicado en 2011

Sperm involved in recurrent partial hydatidiform moles cannot induce the normal pattern of calcium oscillations.

artículo científico publicado en 2014

Strontium fails to induce Ca2+ release and activation in human oocytes despite the presence of functional TRPV3 channels

artículo científico publicado en 2018

The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4- and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation

artículo científico publicado en 2012

The influence of early embryo traits on human embryonic stem cell derivation efficiency

artículo científico publicado en 2010

The post-inner cell mass intermediate: implications for stem cell biology and assisted reproductive technology

artículo científico

Toxic effects of Hoechst staining and UV irradiation on preimplantation development of parthenogenetically activated mouse oocytes

artículo científico publicado en 2012

Tracking the progression of the human inner cell mass during embryonic stem cell derivation

artículo científico publicado en 2012

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

artículo científico publicado en 2013

Two decades of embryonic stem cells: a historical overview

artículo científico publicado en 2019

Untargeted histone profiling during naive conversion uncovers conserved modification markers between mouse and human

scientific article published on 21 November 2019

Use of pluripotent stem cells for reproductive medicine: are we there yet?

artículo científico publicado en 2014

Variance in total levels of phospholipase C zeta (PLC-ζ) in human sperm may limit the applicability of quantitative immunofluorescent analysis as a diagnostic indicator of oocyte activation capability

artículo científico publicado en 2012

Vitrification negatively affects the Ca2+-releasing and activation potential of mouse oocytes, but vitrified oocytes are potentially useful for diagnostic purposes

scientific article published on 28 September 2019

WNT Inhibition and Increased FGF Signaling Promotes Derivation of Less Heterogeneous Primed Human Embryonic Stem Cells, Compatible with Differentiation

scientific article published on 02 April 2019

Whole genome amplification with SurePlex results in better copy number alteration detection using sequencing data compared to the MALBAC method

artículo científico publicado en 2015

Lista de obras de

A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertility

A systematic analysis of the suitability of preimplantation genetic diagnosis for mitochondrial diseases in a heteroplasmic mitochondrial mouse model.

Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells

Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells

Application Of Small Molecules Favoring Naïve Pluripotency during Human Embryonic Stem Cell Derivation

Assessing the impact of minimizing arginine conversion in fully defined SILAC culture medium in human embryonic stem cells

Assessment of nuclear transfer techniques to prevent the transmission of heritable mitochondrial disorders without compromising embryonic development competence in mice

Assessment of the calcium releasing machinery in oocytes that failed to fertilize after conventional ICSI and assisted oocyte activation

Assisted oocyte activation following ICSI fertilization failure

Assisted oocyte activation significantly increases fertilization and pregnancy outcome in patients with low and total failed fertilization after intracytoplasmic sperm injection: a 17-year retrospective study

Bta-miR-10b Secreted by Bovine Embryos Negatively Impacts Preimplantation Embryo Quality

CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells

Cellular Heterogeneity in the Level of mtDNA Heteroplasmy in Mouse Embryonic Stem Cells.

Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile man by use of minisequencing of individual sperm and expression in somatic cells

Chromosomal mosaicism in human blastocysts: the ultimate diagnostic dilemma

Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background.

Contemporary pharmacogenetic assays in view of the PharmGKB database

Culture conditions affect Ca2+ release in artificially activated mouse and human oocytes

Culture medium preferences of pre-implantation cloned mouse embryos

Derivation of human embryonic stem cells using a post-inner cell mass intermediate

Detailed method description for noninvasive monitoring of differentiation status of human embryonic stem cells

Developmental competence of parthenogenetic mouse and human embryos after chemical or electrical activation ⬇️

Diagnosis and Treatment of Male Infertility-Related Fertilization Failure

Differential apoptotic staining of mammalian blastocysts based on double immunofluorescent CDX2 and active caspase-3 staining

Effect of two assisted oocyte activation protocols used to overcome fertilization failure on the activation potential and calcium releasing pattern.

Efficiency of assisted oocyte activation as a solution for failed intracytoplasmic sperm injection

Erratum to: PLCζ disruption with complete fertilization failure in normozoospermia

Erratum. Chromosomal mosaicism in human blastocysts: the ultimate diagnostic dilemma

Establishment and Characterization of Naïve Pluripotency in Human Embryonic Stem Cells.

Exogenous supplementation of Activin A enhances germ cell differentiation of human embryonic stem cells.

Globozoospermia is mainly due to DPY19L2 deletion via non-allelic homologous recombination involving two recombination hotspots.

Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts

Human blastocyst outgrowths recapitulate primordial germ cell specification events

Human embryo research in Belgium: an overview.

Human germline gene editing. Recommendations of ESHG and ESHRE

Human germline gene editing: Recommendations of ESHG and ESHRE.

Identification of histone H3 clipping activity in human embryonic stem cells

Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential

Inhibition of transforming growth factor β signaling promotes epiblast formation in mouse embryos

Language development of children born following intracytoplasmic sperm injection (ICSI) combined with assisted oocyte activation (AOA).

Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes

Metabolic plasticity complements the unique nature and demands of distinct pluripotency states

Modelling human embryogenesis: embryo-like structures spark ethical and policy debate

Mutation-free baby born from a mitochondrial encephalopathy, lactic acidosis and stroke-like syndrome carrier after blastocyst trophectoderm preimplantation genetic diagnosis.

Neonatal and neurodevelopmental outcome of children aged 3-10 years born following assisted oocyte activation

Novel reproductive technologies to prevent mitochondrial disease

PLCζ disruption with complete fertilization failure in normozoospermia

PLCζ is the physiological trigger of the Ca2+ oscillations that induce embryogenesis in mammals but conception can occur in its absence

Pan-cancer pharmacogenetics: targeted sequencing panels or exome sequencing?

Patients with a high proportion of immature and meiotically resistant oocytes experience defective nuclear oocyte maturation patterns and impaired pregnancy outcomes.

Polar body mutation load analysis in a patient with A3243G tRNALeu(UUR) point mutation

Poor correlation between polar bodies and blastomere mutation load in a patient with m.3243A>G tRNALeu(UUR) point mutation.

Preimplantation genetic diagnosis for chromosomal rearrangements with the use of array comparative genomic hybridization at the blastocyst stage

Procaine Induces Cytokinesis in Horse Oocytes via a pH-Dependent Mechanism

Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions

Reference loci for RT-qPCR analysis of differentiating human embryonic stem cells

Responsible innovation in human germline gene editing. Background document to the recommendations of ESHG and ESHRE

Responsible innovation in human germline gene editing: Background document to the recommendations of ESHG and ESHRE.

Robust protocol for feeder-free adaptation of cryopreserved human pluripotent stem cells

Serial pronuclear transfer increases the developmental potential of in vitro-matured oocytes in mouse cloning

Shallow whole genome sequencing is well suited for the detection of chromosomal aberrations in human blastocysts

Single Ca (2+) transients versus oscillatory Ca(2+) signalling: limitations and benefits

Slow controlled-rate freezing of human in vitro matured oocytes: effects on maturation rate and kinetics and parthenogenetic activation

Sperm involved in recurrent partial hydatidiform moles cannot induce the normal pattern of calcium oscillations.

Strontium fails to induce Ca2+ release and activation in human oocytes despite the presence of functional TRPV3 channels

The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4- and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation

The influence of early embryo traits on human embryonic stem cell derivation efficiency

The post-inner cell mass intermediate: implications for stem cell biology and assisted reproductive technology

Toxic effects of Hoechst staining and UV irradiation on preimplantation development of parthenogenetically activated mouse oocytes

Tracking the progression of the human inner cell mass during embryonic stem cell derivation

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

Two decades of embryonic stem cells: a historical overview

Untargeted histone profiling during naive conversion uncovers conserved modification markers between mouse and human

Use of pluripotent stem cells for reproductive medicine: are we there yet?

Variance in total levels of phospholipase C zeta (PLC-ζ) in human sperm may limit the applicability of quantitative immunofluorescent analysis as a diagnostic indicator of oocyte activation capability

Vitrification negatively affects the Ca2+-releasing and activation potential of mouse oocytes, but vitrified oocytes are potentially useful for diagnostic purposes

WNT Inhibition and Increased FGF Signaling Promotes Derivation of Less Heterogeneous Primed Human Embryonic Stem Cells, Compatible with Differentiation

Whole genome amplification with SurePlex results in better copy number alteration detection using sequencing data compared to the MALBAC method