Lista de obras -

A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain

artículo científico publicado en 2016

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin

artículo científico publicado en 2016

A supramolecular assembly mediates lentiviral DNA integration ⬇️

artículo científico publicado en 2017

A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication

artículo científico publicado en 2012

Alteration of select gene expression patterns in individuals infected with HIV-1.

artículo científico publicado en 2014

Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites

artículo científico publicado en 2016

Biochemical characterization of novel retroviral integrase proteins

artículo científico publicado en 2013

Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo

artículo científico publicado en 2016

Correction: Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration

artículo científico publicado en 2016

Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75.

artículo científico publicado en 2014

Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction

artículo científico publicado en 2013

Distinct viral reservoirs in individuals with spontaneous control of HIV-1

artículo científico publicado en 2020

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

artículo científico publicado en 2016

Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro.

artículo científico publicado en 2016

Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction

artículo científico publicado en 2013

HIV-1 integrase inhibitors: 2007-2008 update

artículo científico publicado en 2010

Haematopoietic stem and progenitor cells from human pluripotent stem cells.

artículo científico publicado en 2017

HemoTypeSC Demonstrates >99% Field Accuracy in a Sickle Cell Disease Screening Initiative in Children of Southeastern Uganda

artículo científico publicado en 2019

Host and viral determinants for MxB restriction of HIV-1 infection

artículo científico publicado en 2014

Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding.

artículo científico publicado en 2014

Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration.

artículo científico publicado en 2016

Key determinants of target DNA recognition by retroviral intasomes

artículo científico publicado en 2015

Molecular mechanisms of retroviral integration site selection

artículo científico publicado en 2014

Multicenter Evaluation of HemoTypeSC as a Point-of-Care Sickle Cell Disease Rapid Diagnostic Test for Newborns and Adults Across India

scientific article published on 01 January 2020

Point-of-Care Screening for Sickle-Cell Disease in Low-Resource Settings: a Multi-Center Evaluation of HemoTypeSC, a Novel Rapid Test

scientific article published on 31 October 2018

Proceedings of the Frontiers of Retrovirology Conference 2016.

artículo científico publicado en 2016

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

artículo científico publicado en 2009

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

artículo científico publicado en 2009

Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74.

artículo científico publicado en 2016

Sites of retroviral DNA integration: From basic research to clinical applications

artículo científico publicado en 2015

Structural basis for retroviral integration into nucleosomes.

artículo científico publicado en 2015

Structural basis for spumavirus GAG tethering to chromatin ⬇️

artículo científico publicado en 2017

The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes

artículo científico publicado en 2016

The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency

artículo científico publicado en 2016

Lista de obras de

A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin

A supramolecular assembly mediates lentiviral DNA integration ⬇️

A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication

Alteration of select gene expression patterns in individuals infected with HIV-1.

Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites

Biochemical characterization of novel retroviral integrase proteins

Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo

Correction: Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration

Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75.

Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction

Distinct viral reservoirs in individuals with spontaneous control of HIV-1

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro.

Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction

HIV-1 integrase inhibitors: 2007-2008 update

Haematopoietic stem and progenitor cells from human pluripotent stem cells.

HemoTypeSC Demonstrates >99% Field Accuracy in a Sickle Cell Disease Screening Initiative in Children of Southeastern Uganda

Host and viral determinants for MxB restriction of HIV-1 infection

Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding.

Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration.

Key determinants of target DNA recognition by retroviral intasomes

Molecular mechanisms of retroviral integration site selection

Multicenter Evaluation of HemoTypeSC as a Point-of-Care Sickle Cell Disease Rapid Diagnostic Test for Newborns and Adults Across India

Point-of-Care Screening for Sickle-Cell Disease in Low-Resource Settings: a Multi-Center Evaluation of HemoTypeSC, a Novel Rapid Test

Proceedings of the Frontiers of Retrovirology Conference 2016.

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74.

Sites of retroviral DNA integration: From basic research to clinical applications

Structural basis for retroviral integration into nucleosomes.

Structural basis for spumavirus GAG tethering to chromatin ⬇️

The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes

The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency