Lista de obras -

A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes

scientific article published in Scientific Reports

A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis

artículo científico publicado en 2015

A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo.

artículo científico publicado en 2017

Amyloid persistence in decellularized liver: biochemical and histopathological characterization.

artículo científico publicado en 2015

Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic 2-microglobulin variant

artículo científico publicado en 2011

Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis.

artículo científico publicado en 2013

Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes

artículo científico publicado en 2016

C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis

artículo científico publicado en 2019

Citrate-stabilized gold nanoparticles hinder fibrillogenesis of a pathological variant of β2-microglobulin.

artículo científico publicado en 2017

Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β 2 -Microglobulin

artículo científico publicado en 2014

Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis

artículo científico publicado en 2006

Conformational switching and fibrillogenesis in the amyloidogenic fragment of apolipoprotein a-I.

artículo científico publicado en 2002

Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils

artículo científico publicado en 2010

Effects of the Known Pathogenic Mutations on the Aggregation Pathway of the Amyloidogenic Peptide of Apolipoprotein A-I

article

Equilibrium unfolding thermodynamics of beta2-microglobulin analyzed through native-state H/D exchange

artículo científico publicado en 2009

Folding and fibrillogenesis: clues from beta2-microglobulin.

artículo científico publicado en 2010

Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel.

artículo científico publicado en 2017

Interference of citrate-stabilized gold nanoparticles with β2-microglobulin oligomeric association

artículo científico publicado en 2018

Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis.

artículo científico publicado en 2007

Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue

artículo científico publicado en 2017

Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2-microglobulin

artículo científico publicado en 2016

Monitoring the interaction between β2-microglobulin and the molecular chaperone αB-crystallin by NMR and mass spectrometry: αB-crystallin dissociates β2-microglobulin oligomers.

artículo científico publicado en 2013

Native-unlike long-lived intermediates along the folding pathway of the amyloidogenic protein beta2-microglobulin revealed by real-time two-dimensional NMR.

artículo científico publicado en 2009

Oleuropein aglycone: A polyphenol with different targets against amyloid toxicity.

artículo científico publicado en 2018

Pharmaceutical strategies against amyloidosis: old and new drugs in targeting a "protein misfolding disease".

artículo científico publicado en 2004

Plasminogen activation triggers transthyretin amyloidogenesis

scientific article published in Journal of Biological Chemistry

Properties of Some Variants of Human β2-Microglobulin and Amyloidogenesis

artículo científico publicado en 2003

Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis

artículo científico publicado en 2014

Proteomics in protein misfolding diseases.

artículo científico publicado en 2009

Proteomics of beta2-microglobulin amyloid fibrils.

artículo científico publicado en 2005

Recombinant amyloidogenic domain of ApoA-I: Analysis of its fibrillogenic potential

article

Reduction of conformational mobility and aggregation in W60G β2-microglobulin: assessment by 15N NMR relaxation.

artículo científico publicado en 2013

Solution structure of beta(2)-microglobulin and insights into fibrillogenesis.

artículo científico publicado en 2005

Structural and folding dynamic properties of the T70N variant of human lysozyme.

artículo científico publicado en 2003

Structure, folding dynamics, and amyloidogenesis of D76N β2-microglobulin: roles of shear flow, hydrophobic surfaces, and α-crystallin.

artículo científico publicado en 2013

The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties

artículo científico publicado en 2008

The intracellular quality control system down-regulates the secretion of amyloidogenic apolipoprotein A-I variants: A possible impact on the natural history of the disease

scientific article published on 15 July 2010

Topological investigation of amyloid fibrils obtained from beta2-microglobulin.

artículo científico publicado en 2002

Lista de obras de

A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes

A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis

A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo.

Amyloid persistence in decellularized liver: biochemical and histopathological characterization.

Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic 2-microglobulin variant

Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis.

Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes

C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis

Citrate-stabilized gold nanoparticles hinder fibrillogenesis of a pathological variant of β2-microglobulin.

Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β 2 -Microglobulin

Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis

Conformational switching and fibrillogenesis in the amyloidogenic fragment of apolipoprotein a-I.

Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils

Effects of the Known Pathogenic Mutations on the Aggregation Pathway of the Amyloidogenic Peptide of Apolipoprotein A-I

Equilibrium unfolding thermodynamics of beta2-microglobulin analyzed through native-state H/D exchange

Folding and fibrillogenesis: clues from beta2-microglobulin.

Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel.

Interference of citrate-stabilized gold nanoparticles with β2-microglobulin oligomeric association

Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis.

Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue

Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2-microglobulin

Monitoring the interaction between β2-microglobulin and the molecular chaperone αB-crystallin by NMR and mass spectrometry: αB-crystallin dissociates β2-microglobulin oligomers.

Native-unlike long-lived intermediates along the folding pathway of the amyloidogenic protein beta2-microglobulin revealed by real-time two-dimensional NMR.

Oleuropein aglycone: A polyphenol with different targets against amyloid toxicity.

Pharmaceutical strategies against amyloidosis: old and new drugs in targeting a "protein misfolding disease".

Plasminogen activation triggers transthyretin amyloidogenesis

Properties of Some Variants of Human β2-Microglobulin and Amyloidogenesis

Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis

Proteomics in protein misfolding diseases.

Proteomics of beta2-microglobulin amyloid fibrils.

Recombinant amyloidogenic domain of ApoA-I: Analysis of its fibrillogenic potential

Reduction of conformational mobility and aggregation in W60G β2-microglobulin: assessment by 15N NMR relaxation.

Solution structure of beta(2)-microglobulin and insights into fibrillogenesis.

Structural and folding dynamic properties of the T70N variant of human lysozyme.

Structure, folding dynamics, and amyloidogenesis of D76N β2-microglobulin: roles of shear flow, hydrophobic surfaces, and α-crystallin.

The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties

The intracellular quality control system down-regulates the secretion of amyloidogenic apolipoprotein A-I variants: A possible impact on the natural history of the disease

Topological investigation of amyloid fibrils obtained from beta2-microglobulin.