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A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines

scientific article published on 10 July 2019

A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses

artículo científico publicado en 2022

A single-cell landscape of high-grade serous ovarian cancer

artículo científico publicado en 2020

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

scientific article published on 04 August 2020

Development and Characterization of a Wee1 Kinase Degrader

artículo científico publicado en 2019

Development of CDK2 and CDK5 Dual Degrader TMX-2172

artículo científico publicado en 2020

Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype

artículo científico publicado en 2019

Heterogeneity and Clonal Evolution of Acquired PARP Inhibitor Resistance in <i>TP53-</i> and <i>BRCA1</i>-Deficient Cells

artículo científico

Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity

artículo científico publicado en 2019

Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes

preprint published on 09 August 2021

Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes

artículo científico publicado en 2022

Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity

scientific article published on 06 June 2019

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

artículo científico publicado en 2017

Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells

scientific article published on 04 December 2019