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A higher BMI is not associated with a different immune response and disease course in critically ill COVID-19 patients

artículo científico publicado en 2021

A possible role for the cholinergic anti-inflammatory pathway in increased mortality observed in critically ill patients receiving nicotine replacement therapy

artículo científico publicado en 2007

Acetazolamide-mediated decrease in strong ion difference accounts for the correction of metabolic alkalosis in critically ill patients

artículo científico publicado en 2006

Activation of the ATP-dependent potassium channel attenuates norepinephrine-induced vasoconstriction in the human forearm

artículo científico publicado en 2004

Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial

artículo científico publicado en 2012

Alkaline phosphatase treatment improves renal function in severe sepsis or septic shock patients.

artículo científico publicado en 2009

Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study

artículo científico publicado en 2020

Appointing nurses trained in organ donation to improve family consent rates

scientific article published on 11 July 2019

Association between incident delirium and 28- and 90-day mortality in critically ill adults: a secondary analysis

artículo científico publicado en 2020

Automated patient-ventilator interaction analysis during neurally adjusted non-invasive ventilation and pressure support ventilation in chronic obstructive pulmonary disease

artículo científico publicado en 2014

Biomarkers associated with delirium in critically ill patients and their relation with long-term subjective cognitive dysfunction; indications for different pathways governing delirium in inflamed and noninflamed patients

artículo científico publicado en 2011

Body mass index is not associated with cytokine induction during experimental human endotoxemia

artículo científico publicado el 19 de abril de 2013

Brain resuscitation in the drowning victim

artículo científico publicado en 2012

C1-esterase inhibitor attenuates the inflammatory response during human endotoxemia.

artículo científico publicado en 2010

Capturing early signs of deterioration: the dutch-early-nurse-worry-indicator-score and its value in the Rapid Response System

artículo científico publicado en 2016

Cardiac troponin elevations among critically ill patients

artículo científico publicado en 2004

Cell-type-specific downregulation of heme oxygenase-1 by lipopolysaccharide via Bach1 in primary human mononuclear cells

artículo científico publicado en 2014

Changes in frailty among ICU survivors and associated factors: Results of a one-year prospective cohort study using the Dutch Clinical Frailty Scale

artículo científico publicado en 2019

Circulating adenosine increases during human experimental endotoxemia but blockade of its receptor does not influence the immune response and subsequent organ injury

artículo científico publicado en 2011

Circulating angiopoietin-2 levels in the course of septic shock: relation with fluid balance, pulmonary dysfunction and mortality

artículo científico publicado en 2009

Clinical review: The ABC of weaning failure - a structured approach

artículo científico publicado el 8 de diciembre de 2010

Clinical value of an arterial pressure-based cardiac output measurement device

artículo científico publicado en 2008

Comparison and clinical suitability of eight prediction models for cardiac surgery-related acute kidney injury.

artículo científico publicado en 2012

Comparison of cooling methods to induce and maintain normo- and hypothermia in intensive care unit patients: a prospective intervention study

artículo científico publicado en 2007

Comparison of two percutaneous tracheostomy techniques, guide wire dilating forceps and Ciaglia Blue Rhino: a sequential cohort study

artículo científico publicado en 2004

Contribution of alarm noise to average sound pressure levels in the ICU: An observational cross-sectional study

scientific article published on 10 July 2020

Contribution of various metabolites to the "unmeasured" anions in critically ill patients with metabolic acidosis

artículo científico publicado en 2008

Crew Resource Management in the trauma room: a prospective 3-year cohort study

artículo científico publicado en 2017

Delirium in critically ill patients: impact on long-term health-related quality of life and cognitive functioning

artículo científico publicado en 2012

Development of Endotoxin Tolerance Does Not Influence the Response to a Challenge with the Mucosal Live-Attenuated Influenza Vaccine in Humans In Vivo

artículo científico publicado en 2017

Development of endotoxin tolerance in humans in vivo

artículo científico publicado en 2009

Diaphragm Pathology in Critically Ill Patients With COVID-19 and Postmortem Findings From 3 Medical Centers

scientific article published on 16 November 2020

Differential ex vivo and in vivo endotoxin tolerance kinetics following human endotoxemia*

artículo científico publicado el 1 de agosto de 2011

Dipyridamole augments the antiinflammatory response during human endotoxemia

artículo científico publicado el 30 de noviembre de 2011

Duration of antibiotic treatment: are even numbers odd?

artículo científico publicado en 2005

Dynamic light application therapy to reduce the incidence and duration of delirium in intensive-care patients: a randomised controlled trial

artículo científico publicado en 2016

Dynamic preload indicators decrease when the abdomen is opened

artículo científico publicado en 2014

Early and late outcome after single step dilatational tracheostomy versus the guide wire dilating forceps technique: a prospective randomized clinical trial

artículo científico publicado el 12 de abril de 2011

Effect of Vasopressors on the Macro- and Microcirculation During Systemic Inflammation in Humans In Vivo

artículo científico publicado en 2020

Effect of do-not-resuscitate orders on the penumbra of care

artículo científico publicado el 19 de enero de 2012

Effect of preadmission sunlight exposure on intensive care unit-acquired delirium: a multicenter study.

artículo científico publicado en 2013

Effect of the antihepcidin Spiegelmer lexaptepid on inflammation-induced decrease in serum iron in humans

artículo científico publicado en 2014

Effects of Vagus Nerve Stimulation and Vagotomy on Systemic and Pulmonary Inflammation in a Two-Hit Model in Rats

artículo científico publicado el 6 de abril de 2012

Effects of Viscosity on Cerebral Blood Flow After Cardiac Arrest

artículo científico publicado el 1 de marzo de 2014

Effects of a rapid response system on quality of life: a prospective cohort study in surgical patients before and after implementing a rapid response system

artículo científico publicado el 1 de mayo de 2013

Effects of prolonged mild hypothermia on cerebral blood flow after cardiac arrest

artículo científico publicado el 1 de agosto de 2012

Effects of the 34C>T Variant of the AMPD1 Gene on Immune Function, Multi-Organ Dysfunction, and Mortality in Sepsis Patients

artículo científico publicado en 2015

Effects of the α7 Nicotinic Acetylcholine Receptor Agonist Gts-21 on the Innate Immune Response in Humans

artículo científico publicado el 1 de julio de 2011

Emphysema and pneumothorax after percutaneous tracheostomy: case reports and an anatomic study

artículo científico publicado en 2004

Endotoxemia-induced inflammation and the effect on the human brain

artículo científico publicado en 2010

Endotoxin tolerance does not limit mild ischemia-reperfusion injury in humans in vivo

artículo científico publicado en 2009

Extravascular lung water index and global end-diastolic volume index should be corrected in children

artículo científico publicado el 24 de marzo de 2011

Extravascular lung water index measurement in critically ill children does not correlate with a chest x-ray score of pulmonary edema

artículo científico publicado en 2010

Extravascular lung water index measurement in critically ill children does not correlate with a chest x-ray score of pulmonary edema

F-18-fluorodeoxyglucose positron emission tomography combined with CT in critically ill patients with suspected infection

artículo científico publicado en 2009

Feasibility and safety of hydrotherapy in critically ill ventilated patients

artículo científico publicado en 2015

Financial consequences of the implementation of a rapid response system on a surgical ward

artículo científico publicado en 2014

Flucloxacillin Results in Suboptimal Plasma Voriconazole Concentrations.

artículo científico publicado en 2017

GTS-21 inhibits pro-inflammatory cytokine release independent of the Toll-like receptor stimulated via a transcriptional mechanism involving JAK2 activation.

artículo científico publicado en 2009

Gender differences in the innate immune response and vascular reactivity following the administration of endotoxin to human volunteers.

artículo científico publicado en 2007

Haloperidol prophylaxis in critically ill patients with a high risk for delirium

artículo científico publicado en 2013

Hematological indices, inflammatory markers and neutrophil CD64 expression: comparative trends during experimental human endotoxemia

artículo científico publicado en 2007

Hemodynamic response to β-blockers in severe sepsis and septic shock: A review of current literature

artículo científico publicado en 2018

How systemic inflammation modulates adenosine metabolism and adenosine receptor expression in humans in vivo

artículo científico publicado en 2012

Hypercapnia attenuates ventilator-induced diaphragm atrophy and modulates dysfunction.

artículo científico publicado en 2014

Hyperoxia after cardiac arrest may not increase ischemia-reperfusion injury

artículo científico publicado el 22 de junio de 2011

Hypertonic fluid administration in patients with septic shock: a prospective randomized controlled pilot study

artículo científico publicado en 2012

Hypothermia does not increase the risk of infection: a case control study

artículo científico publicado el 3 de febrero de 2011

Hypoxia attenuates inflammation-induced hepcidin synthesis during experimental human endotoxemia

artículo científico publicado en 2019

Immunologic Consequences of Hypoxia during Critical Illness

artículo científico publicado en 2016

Immunotherapy for the Adjunctive Treatment of Sepsis: From Immunosuppression to Immunostimulation. Time for a Paradigm Change?

artículo científico publicado el 15 de junio de 2013

Impaired renal function is associated with greater urinary strong ion differences in critically ill patients with metabolic acidosis

artículo científico publicado el 27 de julio de 2011

In vivo evidence for nitric oxide-mediated calcium-activated potassium-channel activation during human endotoxemia

artículo científico publicado en 2006

Inadequate Assessment of Patient-Ventilator Interaction Due to Suboptimal Diaphragm Electrical Activity Signal Filtering

artículo científico publicado en 2020

Incidence and short-term consequences of delirium in critically ill patients: A prospective observational cohort study

artículo científico publicado en 2011

Incidence of cardiac arrests and unexpected deaths in surgical patients before and after implementation of a rapid response system

artículo científico publicado el 20 de junio de 2012

Increased risk for secondary infections in trauma patients with viral reactivation

artículo científico publicado en 2016

Inflammation-induced hepatotoxicity in humans

artículo científico publicado en 2009

Inflammation-induced hepcidin-25 is associated with the development of anemia in septic patients: an observational study

artículo científico publicado el 10 de enero de 2011

Influence of different breathing patterns on heart rate variability indices and reproducibility during experimental endotoxaemia in human subjects

artículo científico publicado en 2011

Influence of mild therapeutic hypothermia after cardiac arrest on hospital mortality

artículo científico publicado en 2011

Intensive Insulin Therapy Increases the Risk of Hypoglycemia in Neurocritical Care Patients

artículo científico publicado el 1 de julio de 2011

Intensive insulin therapy does not alter the inflammatory response in patients undergoing coronary artery bypass grafting: a randomized controlled trial [ISRCTN95608630].

artículo científico publicado en 2005

Interplay Between the Acute Inflammatory Response and Heart Rate Variability in Healthy Human Volunteers

artículo científico publicado el 1 de agosto de 2011

Interpretation of the transpulmonary thermodilution curve in the presence of a left-to-right shunt

artículo científico publicado el 9 de diciembre de 2010

Interventions aimed at healthcare professionals to increase the number of organ donors: a systematic review

artículo científico publicado en 2019

Intravenous magnesium in subarachnoid hemorrhage

artículo científico publicado el 24 de mayo de 2011

Invasive pulmonary aspergillosis in influenza

artículo científico publicado en 2015

Iso-osmolar prehydration shifts the cytokine response towards a more anti-inflammatory balance in human endotoxemia

artículo científico publicado en 2005

Lipopolysaccharide-stimulated whole blood cytokine production does not predict the inflammatory response in human endotoxemia

artículo científico publicado en 2009

Low cerebral blood flow after cardiac arrest is not associated with anaerobic cerebral metabolism

artículo científico publicado en 2017

Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy mice

artículo científico publicado en 2008

MONITOR-IC study, a mixed methods prospective multicentre controlled cohort study assessing 5-year outcomes of ICU survivors and related healthcare costs: a study protocol.

artículo científico publicado en 2017

Mechanical ventilation in healthy mice induces reversible pulmonary and systemic cytokine elevation with preserved alveolar integrity: an in vivo model using clinical relevant ventilation settings

scientific article published on 01 September 2007

Mechanical ventilation induces a Toll/interleukin-1 receptor domain-containing adapter-inducing interferon beta-dependent inflammatory response in healthy mice

artículo científico publicado en 2009

Mechanical ventilation-induced intrathoracic pressure distribution and heart-lung interactions*.

artículo científico publicado en 2014

Microcirculation and vascular reactivity during endotoxemia and endotoxin tolerance in humans

artículo científico publicado en 2009

Microvascular permeability during experimental human endotoxemia: an open intervention study

artículo científico publicado en 2005

Modulation of Innate Immunity by Adenosine Receptor Stimulation

artículo científico publicado el 1 de septiembre de 2011

Monitoring of the Respiratory Muscles in the Critically Ill

artículo científico publicado el 26 de octubre de 2012

Monitoring patient-ventilator breath contribution in the critically ill during neurally adjusted ventilatory assist: reliability and improved algorithms for bedside use

scientific article published on 30 May 2019

Near-normal values of extravascular lung water in children

artículo científico publicado en 2015

Nitric oxide inhalation and glucocorticoids as combined treatment in human experimental endotoxemia: It takes not always two to tango

artículo científico publicado en 2009

Non-invasive mechanical ventilation for diagnostic bronchoscopy using a new face mask: an observational feasibility study

artículo científico publicado en 2009

Nonpharmacologic Interventions to Prevent or Mitigate Adverse Long-Term Outcomes Among ICU Survivors: A Systematic Review and Meta-Analysis

scientific article published on 01 November 2019

Nurses' 'worry' as predictor of deteriorating surgical ward patients: A prospective cohort study of the Dutch-Early-Nurse-Worry-Indicator-Score

artículo científico publicado en 2016

Nurses' worry or concern and early recognition of deteriorating patients on general wards in acute care hospitals: a systematic review

artículo científico publicado en 2015

Patient views regarding the impact of hydrotherapy on critically ill ventilated patients: A qualitative exploration study

artículo científico publicado en 2018

Patient-Ventilator Interaction During Noninvasive Ventilation in Subjects With Exacerbation of COPD: Effect of Support Level and Ventilator Mode

artículo científico publicado en 2020

Patterns in Bacterial- and Viral-Induced Immunosuppression and Secondary Infections in the ICU.

artículo científico publicado en 2016

Physical, Mental, and Cognitive Health Status of ICU Survivors Before ICU Admission: A Cohort Study

scientific article published on 16 June 2020

Physician Experiences with Communicating Organ Donation with the Relatives: A Dutch Nationwide Evaluation on Factors that Influence Consent Rates

artículo científico publicado en 2019

Plasma from septic shock patients induces loss of muscle protein.

artículo científico publicado en 2011

Plasma obtained during human endotoxemia increases endothelial albumin permeability in vitro

artículo científico publicado en 2006

Potentially Inadvertent Immunomodulation: Norepinephrine Use in Sepsis

artículo científico publicado en 2016

Predictive value of neurologic prognostic indicators in hypothermia after cardiac arrest

artículo científico publicado en 2011

Predictors of poor neurologic outcome in patients after cardiac arrest treated with hypothermia: A retrospective study

artículo científico publicado el 17 de marzo de 2011

Preserved metabolic coupling and cerebrovascular reactivity during mild hypothermia after cardiac arrest

artículo científico publicado en 2010

Prevention of ICU delirium and delirium-related outcome with haloperidol: a study protocol for a multicenter randomized controlled trial.

artículo científico publicado en 2013

Prophylactic Haloperidol Effects on Long-term Quality of Life in Critically Ill Patients at High Risk for Delirium: Results of the REDUCE Study

scientific article published on 01 August 2019

Protective effects of adenosine A2A agonist during hemorrhagic shock: a simple intervention may result in a complex response

scientific article published on 01 December 2006

Rationing in the intensive care unit in case of full bed occupancy: a survey among intensive care unit physicians

artículo científico publicado en 2016

Recognizing and supporting morally injured ICU professionals during the COVID-19 pandemic

artículo científico publicado en 2020

Reversal of immunoparalysis in humans in vivo: a double-blind, placebo-controlled, randomized pilot study

artículo científico publicado en 2012

Rewarming after hypothermia after cardiac arrest shifts the inflammatory balance*

artículo científico publicado el 1 de abril de 2012

Risk factors for hypoglycaemia in neurocritical care patients

artículo científico publicado el 21 de agosto de 2012

Risk factors for the deterioration of oxygenation ratio in ventilated intensive care unit patients: a retrospective cohort study

artículo científico publicado en 2009

Seventy-two hours of mild hypothermia after cardiac arrest is associated with a lowered inflammatory response during rewarming in a prospective observational study

artículo científico publicado en 2014

Severe vagal response after endotoxin administration in humans

artículo científico publicado en 2004

Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation

artículo científico publicado en 2018

Short-term beneficial effects of methylene blue on kidney damage in septic shock patients.

artículo científico publicado en 2007

Short-term hyperoxia does not exert immunologic effects during experimental murine and human endotoxemia.

artículo científico publicado en 2015

Short-term repeated HRV-16 exposure results in an attenuated immune response in vivo in humans

artículo científico publicado en 2018

Strategies to optimize respiratory muscle function in ICU patients

artículo científico publicado en 2016

Surgical ward nurses' responses to worry: An observational descriptive study

artículo científico publicado en 2018

Systemic inflammation decreases pain threshold in humans in vivo

artículo científico publicado en 2013

Temporal biomarker profiles and their association with ICU acquired delirium: a cohort study.

artículo científico publicado en 2018

The "cross-talk phenomenon" in transpulmonary thermodilution is flow dependent

scientific article published on 09 May 2006

The Effects of Brain Injury on Heart Rate Variability and the Innate Immune Response in Critically Ill Patients

artículo científico publicado el 22 de febrero de 2012

The Implementation of a Multidisciplinary Approach for Potential Organ Donors in the Emergency Department

scientific article published on 01 November 2019

The Influence of Concentration/Meditation on Autonomic Nervous System Activity and the Innate Immune Response

artículo científico publicado en 2012

The Involvement of Danger-Associated Molecular Patterns in the Development of Immunoparalysis in Cardiac Arrest Patients

artículo científico publicado en 2015

The association between ICU level of care and mortality in the Netherlands

artículo científico publicado en 2015

The authors reply

The complement system is activated in a biphasic pattern after coronary artery bypass grafting

artículo científico publicado en 2010

The effect of adenosine receptor agonists on cytokine release by human mononuclear cells depends on the specific Toll-like receptor subtype used for stimulation

artículo científico publicado en 2006

The effect of iron loading and iron chelation on the innate immune response and subclinical organ injury during human endotoxemia: a randomized trial

artículo científico publicado el 15 de noviembre de 2013

The effect of vasopressin on gastric perfusion in catecholamine-dependent patients in septic shock

artículo científico publicado en 2003

The effects of hypertonic fluid administration on the gene expression of inflammatory mediators in circulating leucocytes in patients with septic shock: a preliminary study

artículo científico publicado el 1 de noviembre de 2011

The effects of methylene blue infusion on gastric tonometry and intestinal fatty acid binding protein levels in septic shock patients.

artículo científico publicado en 2010

The impact of critical illness on the expiratory muscles and the diaphragm assessed by ultrasound in mechanical ventilated children

artículo científico publicado en 2020

The impact of delirium on the prediction of in-hospital mortality in intensive care patients

artículo científico publicado en 2010

The influence of esmolol on right ventricular function in early experimental endotoxic shock

scientific article published on 01 September 2018

The nature of unmeasured anions in critically ill patients

artículo científico publicado en 2008

The pulmonary artery catheter in the pediatric intensive care unit: not the way to go

artículo científico publicado en 2012

The reliability of continuous noninvasive finger blood pressure measurement in critically ill children

artículo científico publicado en 2009

The role of cytokines and inducible nitric oxide synthase in endotoxemia-induced endothelial dysfunction

artículo científico publicado en 2010

The role of poly (ADP-ribose) polymerase in ventilator-induced lung injury

artículo científico publicado en 2008

Titin and diaphragm dysfunction in mechanically ventilated rats

artículo científico publicado el 11 de febrero de 2012

Toll-like receptor 4 signaling in ventilator-induced diaphragm atrophy

artículo científico publicado en 2012

Tracheostomy for long-term ventilated patients: a postal survey of ICU practice in The Netherlands

artículo científico publicado en 2003

Transcriptome kinetics of circulating neutrophils during human experimental endotoxemia

artículo científico publicado en 2012

Transvenous vagus nerve stimulation does not modulate the innate immune response during experimental human endotoxemia: a randomized controlled study

artículo científico publicado en 2015

Unexpected left main stem bronchus cardiac output measurement

artículo científico publicado en 2003

Upregulation of renal inducible nitric oxide synthase during human endotoxemia and sepsis is associated with proximal tubule injury.

artículo científico publicado en 2006

Urinary protein profiling in hyperactive delirium and non-delirium cardiac surgery ICU patients

artículo científico publicado el 22 de marzo de 2011

Use of recruitment maneuvers during mechanical ventilation in pediatric and neonatal intensive care units in the Netherlands

artículo científico publicado en 2007

Validation of noninvasive pulse contour cardiac output using finger arterial pressure in cardiac surgery patients requiring fluid therapy

artículo científico publicado en 2014

Validation of the Dutch language version of the Safety Attitudes Questionnaire (SAQ-NL).

artículo científico publicado en 2016

Variation in rates of ICU readmissions and post-ICU in-hospital mortality and their association with ICU discharge practices

artículo científico publicado en 2017

Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans

artículo científico publicado en 2014