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Active Phagocytosis and Diachronic Processing of Calcium Oxalate Monohydrate Crystals in an in vitro Macrophage Model

artículo científico publicado en 2019

An efficient method for differentiation of human induced pluripotent stem cells into hepatocyte-like cells retaining drug metabolizing activity

artículo científico publicado en 2013

Application of Human Induced Pluripotent Stem Cell-Derived Intestinal Organoids as a Model of Epithelial Damage and Fibrosis in Inflammatory Bowel Disease

artículo científico publicado en 2020

Characteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells.

artículo científico publicado en 2016

Clinical evidence of pharmacokinetic changes in thalidomide therapy.

artículo científico publicado en 2012

Comparison of basal gene expression and induction of CYP3As in HepG2 and human fetal liver cells

artículo científico publicado en 2007

Comparison of mRNA expression profiles of drug-metabolizing enzymes and transporters in fresh and cryopreserved cynomolgus monkey hepatocytes

scientific article published on 11 April 2019

Comparison of the inducibility of CYP mRNA exposed to typical inducers in fresh and cryopreserved cynomolgus monkey hepatocytes

scientific article published on 09 March 2020

Contribution of rat embryonic stem cells to xenogeneic chimeras in blastocyst or 8-cell embryo injection and aggregation

scientific article published on 30 October 2018

Cyclic AMP Signaling Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Intestinal Epithelial Cells

scientific article published on 01 August 2018

Cytochrome P450 3As gene expression and testosterone 6 beta-hydroxylase activity in human fetal membranes and placenta at full term

artículo científico publicado en 2010

Determination of p-glycoprotein ATPase activity using luciferase

artículo científico publicado en 2006

Development of Caco-2 cells co-expressing CYP3A4 and NADPH-cytochrome P450 reductase using a human artificial chromosome for the prediction of intestinal extraction ratio of CYP3A4 substrates

artículo científico publicado en 2016

Development of an in vitro cholestatic drug-induced liver injury evaluation system using HepG2-hNTCP-C4 cells in sandwich configuration

scientific article published on 05 August 2019

Differentiation of human induced pluripotent stem cells into functional enterocyte-like cells using a simple method

artículo científico publicado en 2013

Differentiation of monkey embryonic stem cells into hepatocytes and mRNA expression of cytochrome p450 enzymes responsible for drug metabolism: comparison of embryoid body formation conditions and matrices

artículo científico publicado en 2009

Differentiation of monkey embryonic stem cells to hepatocytes by feeder-free dispersion culture and expression analyses of cytochrome p450 enzymes responsible for drug metabolism

artículo científico publicado en 2012

Effect of Celecoxib on Differentiation of Human Induced Pluripotent Stem Cells into Hepatocytes Involves STAT5 Activation

artículo científico publicado en 2018

Effective NADH-dependent oxidation of 7beta-hydroxy-delta8-tetrahydrocannabinol to the corresponding ketone by Japanese monkey hepatic microsomes

artículo científico publicado en 2005

Effects of hypoxia-inducible factor-1α chemical stabilizer, CoCl(2) and hypoxia on gene expression of CYP3As in human fetal liver cells

artículo científico publicado en 2012

Efficient Generation of Cynomolgus Monkey Induced Pluripotent Stem Cell-Derived Intestinal Organoids with Pharmacokinetic Functions

artículo científico publicado en 2018

Efficient differentiation and purification of human induced pluripotent stem cell-derived endothelial progenitor cells and expansion with the use of inhibitors of ROCK, TGF-β, and GSK3β

artículo científico publicado en 2020

Establishment and directed differentiation of induced pluripotent stem cells from glycogen storage disease type Ib patient

artículo científico publicado en 2013

Establishment of a novel culture method for maintaining intestinal stem cells derived from human induced pluripotent stem cells

artículo científico publicado en 2020

Evaluation of Human Embryonic Stem Cell-derived Hepatocyte-like Cells for Detection of CYP1A Inducers

artículo científico publicado el 29 de mayo de 2012

Expression and induction of CYP3As in human fetal hepatocytes

artículo científico publicado en 2004

Expression of cytochrome P450 and transcription factors during in vitro differentiation of mouse embryonic stem cells into hepatocytes

artículo científico publicado en 2008

Formation of large vacuoles induced by cooperative effects of oncostatin M and dexamethasone in human fetal liver cells

artículo científico publicado en 2008

Functional analysis of carboxylesterase in human induced pluripotent stem cell-derived enterocytes

artículo científico publicado en 2017

Gellan Gum Promotes the Differentiation of Enterocytes from Human Induced Pluripotent Stem Cells

artículo científico publicado en 2020

Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells.

artículo científico publicado en 2018

Generation of enterocyte-like cells with pharmacokinetic functions from human induced pluripotent stem cells using small-molecule compounds

artículo científico publicado en 2015

Hepatocyte nuclear factor 6 activates the transcription of CYP3A4 in hepatocyte-like cells differentiated from human induced pluripotent stem cells.

artículo científico publicado en 2013

Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells

artículo científico publicado en 2014

Human small intestinal epithelial cells differentiated from adult intestinal stem cells as a novel system for predicting oral drug absorption in humans

artículo científico publicado en 2014

Inhibition of mitogen-activated protein kinase kinase, DNA methyltransferase, and transforming growth factor-β promotes differentiation of human induced pluripotent stem cells into enterocytes

artículo científico publicado en 2016

Inhibition of transforming growth factor beta signaling pathway promotes differentiation of human induced pluripotent stem cell-derived brain microvascular endothelial-like cells

scientific article published on 26 May 2020

In vitro bile acid-dependent hepatocyte toxicity assay system using human induced pluripotent stem cell-derived hepatocytes: Current status and disadvantages to overcome

artículo científico publicado en 2019

Isolation of induced pluripotent stem cell-derived endothelial progenitor cells from sac-like structures

artículo científico publicado en 2019

Laminin 221 fragment is suitable for the differentiation of human induced pluripotent stem cells into brain microvascular endothelial-like cells with robust barrier integrity

scientific article published on 30 March 2020

Lower Expression of HNF4α and PGC1α Might Impair Rifampicin-mediated CYP3A4 Induction under Conditions Where PXR Is Overexpressed in Human Fetal Liver Cells

artículo científico publicado el 14 de febrero de 2012

Mechanisms of CYP3A Induction by Glucocorticoids in Human Fetal Liver Cells

artículo científico publicado el 22 de mayo de 2012

Pharmacokinetic functions of human induced pluripotent stem cell-derived small intestinal epithelial cells

artículo científico publicado en 2020

Role of dexamethasone and oncostatin M on the formation of vacuoles in human fetal liver cells.

artículo científico publicado en 2009

Selective culture method for hepatocyte-like cells differentiated from human induced pluripotent stem cells

artículo científico publicado en 2014

Stereospecific and regioselective hydrolysis of cannabinoid esters by ES46.5K, an esterase from mouse hepatic microsomes, and its differences from carboxylesterases of rabbit and porcine liver

artículo científico publicado en 2005

Stimulatory effects of testosterone and progesterone on the NADH- and NADPH-dependent oxidation of 7beta-hydroxy-delta8-tetrahydrocannabinol to 7-oxo-delta8-tetrahydrocannabinol in monkey liver microsomes

artículo científico publicado en 2005

Using human iPS cell-derived enterocytes as novel in vitro model for the evaluation of human intestinal mucosal damage

article