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1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA

artículo científico publicado en 2010

1alpha,25-dihydroxy vitamin D3-enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1alpha,25-dihydroxy vitamin D3 receptor-SRC-1 coactivator complex

scientific journal article

A functional N-terminal domain in C/EBPβ-LAP* is required for interacting with SWI/SNF and to repress Ric-8B gene transcription in osteoblasts

artículo científico publicado en 2014

Altered chromatin modifications in AML1/RUNX1 breakpoint regions involved in (8;21) translocation.

artículo científico publicado en 2009

An architectural genetic and epigenetic perspective

scientific article published on 24 December 2010

An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition.

artículo científico publicado en 2006

An architectural perspective of vitamin D responsiveness.

artículo científico publicado en 2007

Analysis of in vivo gene expression using epitope-tagged proteins

artículo científico publicado en 2004

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information

artículo científico publicado en 2010

Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments

artículo científico publicado en 2010

Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells

scientific journal article

Bookmarking target genes in mitosis: a shared epigenetic trait of phenotypic transcription factors and oncogenes?

artículo científico publicado en 2014

Bookmarking the genome: maintenance of epigenetic information.

artículo científico publicado en 2011

Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes

artículo científico publicado en 2006

C/EBPβ binds the P1 promoter of the Runx2 gene and up-regulates Runx2 transcription in osteoblastic cells

artículo científico publicado en 2011

CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.

artículo científico publicado en 2001

Chromatin immunoprecipitation

scientific article published on 01 January 2004

Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells.

artículo científico publicado en 2008

Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity

artículo científico publicado en 2006

Chromatin remodeling by SWI/SNF results in nucleosome mobilization to preferential positions in the rat osteocalcin gene promoter

artículo científico publicado en 2007

Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats)

artículo científico publicado en 2008

Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer

artículo científico publicado en 2005

Crystallization and preliminary X-ray analysis of a domain in the Runx2 transcription factor that interacts with the 1α,25 dihydroxy vitamin D3 receptor

artículo científico publicado en 2007

Differential roles of NMDA Receptor Subtypes NR2A and NR2B in dendritic branch development and requirement of RasGRF1.

artículo científico publicado en 2010

Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene.

artículo científico publicado en 2004

Downregulation of the Polycomb-Associated Methyltransferase Ezh2 during Maturation of Hippocampal Neurons Is Mediated by MicroRNAs Let-7 and miR-124

artículo científico publicado en 2020

Enhanced CRAd Activity Using Enhancer Motifs Driven by a Nucleosome Positioning Sequence

artículo científico publicado el 28 de mayo de 2013

Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Caused by Ovariectomy in Skeletally Mature Mice

artículo científico publicado en 2016

Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2

artículo científico publicado en 2015

Epigenetic Control of the Bone-master Runx2 Gene during Osteoblast-lineage Commitment by the Histone Demethylase JARID1B/KDM5B.

artículo científico publicado en 2015

Epigenetic Signatures at the RUNX2-P1 and Sp7 Gene Promoters Control Osteogenic Lineage Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells

artículo científico publicado en 2016

Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle.

artículo científico publicado en 2012

Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer's disease mice

artículo científico publicado en 2017

Epigenetic regulation of early osteogenesis and mineralized tissue formation by a HOXA10-PBX1-associated complex

artículo científico publicado en 2011

Epigenetic silencing of the osteoblast-lineage gene program during hippocampal maturation

scientific article published on 02 November 2020

Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and bone-related transcription factor RUNX2

artículo científico publicado en 2018

Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons

scientific journal article

Ezh2-dependent H3K27me3 modification dynamically regulates vitamin D3-dependent epigenetic control of CYP24A1 gene expression in osteoblastic cells

scientific article published on 07 January 2020

Functional Annotation of All Salmonid Genomes (FAASG): an international initiative supporting future salmonid research, conservation and aquaculture

artículo científico publicado en 2017

Functional Diversification of SRSF Protein Kinase to Control Ubiquitin-Dependent Neurodevelopmental Signaling

artículo científico publicado en 2020

Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair.

artículo científico publicado en 2003

Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer

scientific article published on August 2008

Genomic occupancy of HLH, AP1 and Runx2 motifs within a nuclease sensitive site of the Runx2 gene

artículo científico publicado en 2013

Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility

artículo científico publicado en 2011

HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes.

artículo científico publicado en 2007

Histone acetylation in vivo at the osteocalcin locus is functionally linked to vitamin D-dependent, bone tissue-specific transcription

artículo científico publicado en 2002

Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells

artículo científico publicado en 2015

Immunofluorescence analysis using epitope-tagged proteins: in vitro system

scientific article published on 01 January 2004

In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling

artículo científico publicado en 2004

In situ immunofluorescence analysis: immunofluorescence microscopy

scientific article published on 01 January 2004

In situ nuclear organization of regulatory machinery

artículo científico publicado en 2008

Interaction of the 1alpha,25-dihydroxyvitamin D3 receptor at the distal promoter region of the bone-specific osteocalcin gene requires nucleosomal remodelling

scientific journal article

Intranuclear Trafficking: Organization and Assembly of Regulatory Machinery for Combinatorial Biological Control

artículo científico publicado en 2004

Intranuclear organization of RUNX transcriptional regulatory machinery in biological control of skeletogenesis and cancer

artículo científico publicado en 2003

Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.

artículo científico publicado en 2003

Maintenance of open chromatin and selective genomic occupancy at the cell cycle-regulated histone H4 promoter during differentiation of HL-60 promyelocytic leukemia cells

artículo científico publicado en 2003

Mitotic Inheritance of mRNA Facilitates Translational Activation of the Osteogenic-Lineage Commitment Factor Runx2 in Progeny of Osteoblastic Cells.

artículo científico publicado en 2015

Mitotic bookmarking of genes: a novel dimension to epigenetic control.

artículo científico publicado en 2010

Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.

artículo científico publicado en 2007

Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.

artículo científico publicado en 2007

Mll-COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 in osteoblasts

scientific article published on 07 September 2018

Molecular switches involving homeodomain proteins, HOXA10 and RUNX2 regulate osteoblastogenesis

artículo científico publicado en 2008

Multiple levels of epigenetic control for bone biology and pathology

artículo científico publicado en 2015

Mutation of the highly conserved Arg165 and Glu168 residues of human Gsalpha disrupts the alphaD-alphaE loop and enhances basal GDP/GTP exchange rate.

artículo científico publicado en 2004

Networks and hubs for the transcriptional control of osteoblastogenesis.

artículo científico publicado en 2006

Nuclear microenvironments in biological control and cancer.

artículo científico publicado en 2007

Nuclear microenvironments support assembly and organization of the transcriptional regulatory machinery for cell proliferation and differentiation

artículo científico publicado en 2004

Nuclear microenvironments support physiological control of gene expression

artículo científico publicado en 2003

Nucleosome organization and targeting of SWI/SNF chromatin-remodeling complexes: contributions of the DNA sequence

artículo científico publicado en 2007

Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer

artículo científico publicado en 2007

Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer

artículo científico publicado en 2009

PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors.

artículo científico publicado en 2014

Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors

artículo científico publicado en 2010

Phenotypic transcription factors epigenetically mediate cell growth control.

artículo científico publicado en 2008

Phosphorylation at serine 208 of the 1alpha,25-dihydroxy Vitamin D3 receptor modulates the interaction with transcriptional coactivators

artículo científico publicado en 2007

Polycomb PRC2 complex mediates epigenetic silencing of a critical osteogenic master regulator in the hippocampus

artículo científico publicado en 2016

Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing

artículo científico publicado en 2017

Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.

artículo científico publicado en 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay

scientific article published on 01 January 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction

artículo científico publicado en 2004

Recruitment and subnuclear distribution of the regulatory machinery during 1alpha,25-dihydroxy vitamin D3-mediated transcriptional upregulation in osteoblasts

artículo científico publicado en 2010

Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblasts

artículo científico publicado en 2002

Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity

scientific journal article

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

artículo científico publicado en 2004

Ric‐8: Different cellular roles for a heterotrimeric G‐protein GEF

artículo científico publicado el 1 de septiembre de 2012

Runx1 and C/EBPβ transcription factors directly up-regulate P2X3 gene transcription

scientific article published on 01 April 2012

Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression

artículo científico publicado en 2004

Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions

artículo científico publicado en 2003

SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation

scientific journal article

SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2.

scientific article published on August 2009

Ski Is Required for Tri-Methylation of H3K9 in Major Satellite and for Repression of Pericentromeric Genes: Mmp3, Mmp10 and Mmp13, in Mouse Fibroblasts

artículo científico publicado en 2020

Subnuclear localization and intranuclear trafficking of transcription factors

artículo científico publicado en 2010

Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes.

artículo científico publicado en 2009

Switches in histone modifications epigenetically control vitamin D3-dependent transcriptional upregulation of the CYP24A1 gene in osteoblastic cells

artículo científico publicado en 2019

Symbolic extensions applied to multiscale structure of genomes

artículo científico publicado en 2014

Tet-Mediated DNA Demethylation Is Required for SWI/SNF-Dependent Chromatin Remodeling and Histone-Modifying Activities That Trigger Expression of the Sp7 Osteoblast Master Gene during Mesenchymal Lineage Commitment.

artículo científico publicado en 2017

The 1alpha,25-dihydroxy Vitamin D3 receptor preferentially recruits the coactivator SRC-1 during up-regulation of the osteocalcin gene

artículo científico publicado en 2007

The Ric-8B gene is highly expressed in proliferating preosteoblastic cells and downregulated during osteoblast differentiation in a SWI/SNF- and C/EBPbeta-mediated manner

artículo científico publicado en 2011

The Runx2 transcription factor plays a key role in the 1alpha,25-dihydroxy Vitamin D3-dependent upregulation of the rat osteocalcin (OC) gene expression in osteoblastic cells

artículo científico publicado en 2004

The architectural organization of human stem cell cycle regulatory machinery

scientific journal article

The classic receptor for 1alpha,25-dihydroxy vitamin D3 is required for non-genomic actions of 1alpha,25-dihydroxy vitamin D3 in osteosarcoma cells

artículo científico publicado en 2006

The dynamic architectural and epigenetic nuclear landscape: developing the genomic almanac of biology and disease.

artículo científico publicado en 2014

The dynamic organization of gene-regulatory machinery in nuclear microenvironments

artículo científico publicado en 2005

The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes

artículo científico publicado en 2010

The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes.

artículo científico publicado en 2008

The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain

artículo científico publicado en 2004

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer

artículo científico publicado en 2009

Transcription of the pain-related TRPV1 gene requires Runx1 and C/EBPβ factors

artículo científico publicado en 2013

Transcription-factor-mediated epigenetic control of cell fate and lineage commitment

scientific article published on February 2009

Variable transcriptional responsiveness of the P2 × 3 receptor gene during CFA-induced inflammatory hyperalgesia

artículo científico publicado en 2017

Vitamin D control of gene expression: temporal and spatial parameters for organization of the regulatory machinery

artículo científico publicado en 2008

Wnt/β-catenin signaling enhances transcription of the CX43 gene in murine Sertoli cells

artículo científico publicado en 2018