Lista de obras -

A Phosphorylated Intermediate in the Activation of WNK Kinases

scientific article published on 21 April 2020

Characterization of mitogen-activated protein kinase (MAPK) dimers.

artículo científico publicado en 2006

Chloride Sensing by WNK1 Involves Inhibition of Autophosphorylation

artículo científico publicado en 2014

Crystal structure of domain-swapped STE20 OSR1 kinase domain

artículo científico publicado en 2009

Crystal structure of the TAO2 kinase domain: activation and specificity of a Ste20p MAP3K

scientific journal article

Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension

artículo científico publicado en 2004

Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b

artículo científico publicado en 2002

Crystallization of MAP kinases

artículo científico publicado en 2006

Discovery of novel TAOK2 inhibitor scaffolds from high-throughput screening

artículo científico publicado en 2016

Docking interactions induce exposure of activation loop in the MAP kinase ERK2

scientific article published on 01 June 2006

Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry

artículo científico publicado en 2004

Domain-Swapping Switch Point in Ste20 Protein Kinase SPAK

artículo científico publicado en 2015

Functional divergence caused by mutations in an energetic hotspot in ERK2

scientific article published on 11 July 2019

How activating mutations affect MEK1 regulation and function

artículo científico publicado en 2017

Intracellular Chloride and Scaffold Protein Mo25 Cooperatively Regulate Transepithelial Ion Transport through WNK Signaling in the Malpighian Tubule.

artículo científico publicado en 2018

MAP kinase modules: the excursion model and the steps that count

artículo científico publicado en 2014

Modeling of the spatial structure of eukaryotic ornithine decarboxylases ⬇️

artículo científico publicado el 1 de julio de 1995

Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase

artículo científico publicado en 2004

Mutations in ERK2 Binding Sites Affect Nuclear Entry

scientific article published in Journal of Biological Chemistry

Precisely ordered phosphorylation reactions in the p38 mitogen-activated protein (MAP) kinase cascade

artículo científico publicado en 2013

Properties of WNK1 and implications for other family members

artículo científico publicado en 2005

Regulation of WNK1 by an autoinhibitory domain and autophosphorylation

artículo científico publicado en 2002

Solution structure of the WNK1 autoinhibitory domain, a WNK-specific PF2 domain

artículo científico publicado en 2013

Structural Plasticity of Malaria Dihydroorotate Dehydrogenase Allows Selective Binding of Diverse Chemical Scaffolds

artículo científico publicado en 2009

Structural Studies of MAP Kinase Cascade Components ⬇️

artículo científico publicado el 1 de enero de 2010

Structure of MAPKs.

artículo científico publicado en 2004

Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential

artículo científico publicado en 2011

Substrate and docking interactions in serine/threonine protein kinases

artículo científico publicado en 2007

The Structure of the MAP2K MEK6 Reveals an Autoinhibitory Dimer

artículo científico publicado en 2009

The third conformation of p38α MAP kinase observed in phosphorylated p38α and in solution

artículo científico publicado en 2010

Unique MAP Kinase binding sites

artículo científico publicado en 2007

WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding

artículo científico publicado en 2004

WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension

artículo científico publicado en 2005

X-ray Structure of Paramecium bursaria Chlorella Virus Arginine Decarboxylase: Insight into the Structural Basis for Substrate Specificity †

artículo científico publicado en 2007

Lista de obras de

A Phosphorylated Intermediate in the Activation of WNK Kinases

Characterization of mitogen-activated protein kinase (MAPK) dimers.

Chloride Sensing by WNK1 Involves Inhibition of Autophosphorylation

Crystal structure of domain-swapped STE20 OSR1 kinase domain

Crystal structure of the TAO2 kinase domain: activation and specificity of a Ste20p MAP3K

Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension

Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b

Crystallization of MAP kinases

Discovery of novel TAOK2 inhibitor scaffolds from high-throughput screening

Docking interactions induce exposure of activation loop in the MAP kinase ERK2

Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry

Domain-Swapping Switch Point in Ste20 Protein Kinase SPAK

Functional divergence caused by mutations in an energetic hotspot in ERK2

How activating mutations affect MEK1 regulation and function

Intracellular Chloride and Scaffold Protein Mo25 Cooperatively Regulate Transepithelial Ion Transport through WNK Signaling in the Malpighian Tubule.

MAP kinase modules: the excursion model and the steps that count

Modeling of the spatial structure of eukaryotic ornithine decarboxylases ⬇️

Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase

Mutations in ERK2 Binding Sites Affect Nuclear Entry

Precisely ordered phosphorylation reactions in the p38 mitogen-activated protein (MAP) kinase cascade

Properties of WNK1 and implications for other family members

Regulation of WNK1 by an autoinhibitory domain and autophosphorylation

Solution structure of the WNK1 autoinhibitory domain, a WNK-specific PF2 domain

Structural Plasticity of Malaria Dihydroorotate Dehydrogenase Allows Selective Binding of Diverse Chemical Scaffolds

Structural Studies of MAP Kinase Cascade Components ⬇️

Structure of MAPKs.

Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential

Substrate and docking interactions in serine/threonine protein kinases

The Structure of the MAP2K MEK6 Reveals an Autoinhibitory Dimer

The third conformation of p38α MAP kinase observed in phosphorylated p38α and in solution

Unique MAP Kinase binding sites

WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding

WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension

X-ray Structure of Paramecium bursaria Chlorella Virus Arginine Decarboxylase: Insight into the Structural Basis for Substrate Specificity †