Lista de obras -

A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation

A mechanism for the suppression of interleukin-1-induced nuclear factor kappaB activation by protein phosphatase 2Ceta-2.

artículo científico publicado en 2009

A redox-sensitive peroxiredoxin that is important for longevity has tissue- and stress-specific roles in stress resistance

scholarly article

A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase

artículo científico publicado en 2003

Ablation of TAK1 upregulates reactive oxygen species and selectively kills tumor cells

artículo científico publicado en 2010

Activation mechanism of c-Jun amino-terminal kinase in the course of neural differentiation of P19 embryonic carcinoma cells

artículo científico publicado en 2004

An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans

artículo científico publicado en 2003

Axon Regeneration Is Regulated by Ets-C/EBP Transcription Complexes Generated by Activation of the cAMP/Ca2+ Signaling Pathways

artículo científico publicado en 2015

Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways ⬇️

artículo científico publicado el 13 de junio de 2011

Axotomy-induced HIF-serotonin signalling axis promotes axon regeneration in C. elegans

artículo científico publicado en 2016

C. elegans Tensin Promotes Axon Regeneration by Linking the Met-like SVH-2 and Integrin Signaling Pathways

artículo científico publicado en 2019

Caenorhabditis elegans F-Box Protein Promotes Axon Regeneration by Inducing Degradation of the Mad Transcription Factor

artículo científico publicado en 2021

Caenorhabditis elegans FOS-1 and JUN-1 regulate plc-1 expression in the spermatheca to control ovulation

artículo científico publicado en 2009

Caenorhabditis elegans WNK-STE20 pathway regulates tube formation by modulating ClC channel activity

artículo científico publicado en 2007

Chaperone complex BAG2-HSC70 regulates localization of Caenorhabditis elegans leucine-rich repeat kinase LRK-1 to the Golgi.

artículo científico publicado en 2016

Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade

artículo científico publicado en 2003

Delta1 family members are involved in filopodial actin formation and neuronal cell migration independent of Notch signaling.

artículo científico publicado en 2010

Dysregulated LRRK2 Signaling in Response to Endoplasmic Reticulum Stress Leads to Dopaminergic Neuron Degeneration in C. elegans ⬇️

artículo científico publicado el 3 de agosto de 2011

EGFR-dependent phosphorylation of leucine-rich repeat kinase LRRK1 is important for proper endosomal trafficking of EGFR ⬇️

artículo científico publicado el 15 de febrero de 2012

Elucidation of the c-Jun N-terminal kinase pathway mediated by Estein-Barr virus-encoded latent membrane protein 1.

artículo científico publicado en 2004

Endocannabinoid signaling regulates regenerative axon navigation in Caenorhabditis elegans via the GPCRs NPR-19 and NPR-32.

artículo científico publicado en 2016

Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling

artículo científico publicado en 2012

Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis

artículo científico publicado en 2008

Epithelial transforming growth factor β-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species

artículo científico publicado en 2012

Essential function for the kinase TAK1 in innate and adaptive immune responses

artículo científico publicado en 2005

Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos

artículo científico publicado en 2007

Forgetting in C. elegans Is Accelerated by Neuronal Communication via the TIR-1/JNK-1 Pathway ⬇️

artículo científico publicado el 21 de marzo de 2013

Homodimerization of Nemo-like kinase is essential for activation and nuclear localization

artículo científico publicado en 2010

Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol

artículo científico publicado en 2002

Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation

artículo científico publicado en 2004

LRRK1 phosphorylation of Rab7 at S72 links trafficking of EGFR-containing endosomes to its effector RILP

scientific article published on 03 June 2019

LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2.

artículo científico publicado en 2015

LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends

artículo científico publicado en 2014

LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends.

artículo científico publicado en 2015

LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans

artículo científico publicado en 2009

Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor ⬇️

artículo científico publicado el 18 de enero de 2011

MAP kinase cascades regulating axon regeneration in C. elegans

artículo científico publicado en 2015

N-Glycosylation of the Discoidin Domain Receptor Is Required for Axon Regeneration in Caenorhabditis elegans

artículo científico publicado en 2019

NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells ⬇️

artículo científico publicado el 28 de febrero de 2012

Nemo-like kinase is involved in NGF-induced neurite outgrowth via phosphorylating MAP1B and paxillin

artículo científico publicado en 2009

Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex

artículo científico

Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways

artículo científico publicado en 2006

Osmotic stress blocks NF-kappaB-dependent inflammatory responses by inhibiting ubiquitination of IkappaB.

artículo científico publicado en 2007

PLK1-dependent activation of LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2.

artículo científico publicado en 2015

Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration

artículo científico publicado en 2018

Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans

artículo científico publicado en 2010

Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway

artículo científico publicado en 2006

ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

artículo científico publicado en 2005

Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6

artículo científico publicado en 2002

Regulation of ERK activity duration by Sprouty contributes to dorsoventral patterning

artículo científico publicado en 2009

Regulation of anoxic death in Caenorhabditis elegans by mammalian apoptosis signal-regulating kinase (ASK) family proteins

artículo científico publicado en 2011

Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling

artículo científico publicado en 2003

Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3.

artículo científico publicado en 2005

Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon)

artículo científico publicado en 2003

Role of the Caenorhabditis elegans Shc adaptor protein in the c-Jun N-terminal kinase signaling pathway

artículo científico publicado en 2008

Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

artículo científico publicado en 2003

Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction

artículo científico publicado en 2004

Roles of MAP kinase cascades in Caenorhabditis elegans

artículo científico publicado en 2004

SEK-1 MAPKK mediates Ca2+ signaling to determine neuronal asymmetric development in Caenorhabditis elegans

artículo científico publicado en 2001

STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation

artículo científico publicado en 2005

Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the inhibitor Sprouty

artículo científico publicado en 2004

Signal transduction cascades in axon regeneration: insights from C. elegans

artículo científico publicado en 2017

Suppression of PPAR transactivation switches cell fate of bone marrow stem cells from adipocytes into osteoblasts

artículo científico publicado en 2007

TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling

artículo científico publicado en 2003

TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms

artículo científico publicado en 2012

TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation

artículo científico publicado en 2007

TAK1 binding protein 2 is essential for liver protection from stressors

artículo científico publicado en 2014

TAK1 determines susceptibility to endoplasmic reticulum stress and leptin resistance in the hypothalamus.

artículo científico publicado en 2016

TAK1 is a central mediator of NOD2 signaling in epidermal cells

artículo científico publicado en 2007

TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.

artículo científico publicado en 2006

TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis

artículo científico publicado en 2006

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

artículo científico publicado en 2003

TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration

artículo científico publicado en 2012

TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation

artículo científico publicado en 2014

TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity

artículo científico publicado en 2008

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

artículo científico publicado en 2005

TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signaling

artículo científico publicado en 2008

TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway

artículo científico publicado en 2005

TDP2 negatively regulates axon regeneration by inducing SUMOylation of an Ets transcription factor

artículo científico publicado en 2019

TGF-beta-activated kinase 1 signaling maintains intestinal integrity by preventing accumulation of reactive oxygen species in the intestinal epithelium

artículo científico publicado en 2010

TGF-β-activated kinase 1 mediates mechanical stress-induced IL-6 expression in osteoblasts

artículo científico publicado en 2011

Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis

scientific journal article

The C. elegans Discoidin Domain Receptor DDR-2 Modulates the Met-like RTK-JNK Signaling Pathway in Axon Regeneration

artículo científico publicado en 2016

The C. elegans HGF/plasminogen-like protein SVH-1 has protease-dependent and -independent functions

artículo científico publicado en 2014

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

artículo científico publicado en 2005

The C. elegans BRCA2-ALP/Enigma Complex Regulates Axon Regeneration via a Rho GTPase-ROCK-MLC Phosphorylation Pathway

artículo científico publicado en 2018

The Caenorhabditis elegans JNK Signaling Pathway Activates Expression of Stress Response Genes by Derepressing the Fos/HDAC Repressor Complex ⬇️

artículo científico publicado el 21 de febrero de 2013

The Caenorhabditis elegans Ste20-related kinase and Rac-type small GTPase regulate the c-Jun N-terminal kinase signaling pathway mediating the stress response

artículo científico publicado en 2009

The Core Molecular Machinery Used for Engulfment of Apoptotic Cells Regulates the JNK Pathway Mediating Axon Regeneration in Caenorhabditis elegans

artículo científico publicado en 2016

The ERK-MAPK pathway regulates longevity through SKN-1 and insulin-like signaling in Caenorhabditis elegans

artículo científico publicado en 2010

The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling

artículo científico publicado en 2003

The germinal center kinase GCK-1 is a negative regulator of MAP kinase activation and apoptosis in the C. elegans germline

artículo científico publicado en 2009

The growth factor SVH-1 regulates axon regeneration in C. elegans via the JNK MAPK cascade ⬇️

artículo científico publicado el 4 de marzo de 2012

Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway

artículo científico publicado en 2009

WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.

artículo científico publicado en 2005

Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK

artículo científico publicado en 2004

[MAP kinase cascade regulating synaptic vesicle localization in C. elegans as a model animal]

scientific article published on 01 September 2002

Lista de obras de

A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation

A mechanism for the suppression of interleukin-1-induced nuclear factor kappaB activation by protein phosphatase 2Ceta-2.

A redox-sensitive peroxiredoxin that is important for longevity has tissue- and stress-specific roles in stress resistance

A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase

Ablation of TAK1 upregulates reactive oxygen species and selectively kills tumor cells

Activation mechanism of c-Jun amino-terminal kinase in the course of neural differentiation of P19 embryonic carcinoma cells

An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans

Axon Regeneration Is Regulated by Ets-C/EBP Transcription Complexes Generated by Activation of the cAMP/Ca2+ Signaling Pathways

Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways ⬇️

Axotomy-induced HIF-serotonin signalling axis promotes axon regeneration in C. elegans

C. elegans Tensin Promotes Axon Regeneration by Linking the Met-like SVH-2 and Integrin Signaling Pathways

Caenorhabditis elegans F-Box Protein Promotes Axon Regeneration by Inducing Degradation of the Mad Transcription Factor

Caenorhabditis elegans FOS-1 and JUN-1 regulate plc-1 expression in the spermatheca to control ovulation

Caenorhabditis elegans WNK-STE20 pathway regulates tube formation by modulating ClC channel activity

Chaperone complex BAG2-HSC70 regulates localization of Caenorhabditis elegans leucine-rich repeat kinase LRK-1 to the Golgi.

Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade

Delta1 family members are involved in filopodial actin formation and neuronal cell migration independent of Notch signaling.

Dysregulated LRRK2 Signaling in Response to Endoplasmic Reticulum Stress Leads to Dopaminergic Neuron Degeneration in C. elegans ⬇️

EGFR-dependent phosphorylation of leucine-rich repeat kinase LRRK1 is important for proper endosomal trafficking of EGFR ⬇️

Elucidation of the c-Jun N-terminal kinase pathway mediated by Estein-Barr virus-encoded latent membrane protein 1.

Endocannabinoid signaling regulates regenerative axon navigation in Caenorhabditis elegans via the GPCRs NPR-19 and NPR-32.

Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling

Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis

Epithelial transforming growth factor β-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species

Essential function for the kinase TAK1 in innate and adaptive immune responses

Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos

Forgetting in C. elegans Is Accelerated by Neuronal Communication via the TIR-1/JNK-1 Pathway ⬇️

Homodimerization of Nemo-like kinase is essential for activation and nuclear localization

Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol

Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation

LRRK1 phosphorylation of Rab7 at S72 links trafficking of EGFR-containing endosomes to its effector RILP

LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2.

LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends

LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends.

LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans

Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor ⬇️

MAP kinase cascades regulating axon regeneration in C. elegans

N-Glycosylation of the Discoidin Domain Receptor Is Required for Axon Regeneration in Caenorhabditis elegans

NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells ⬇️

Nemo-like kinase is involved in NGF-induced neurite outgrowth via phosphorylating MAP1B and paxillin

Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex

Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways

Osmotic stress blocks NF-kappaB-dependent inflammatory responses by inhibiting ubiquitination of IkappaB.

PLK1-dependent activation of LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2.

Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration

Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans

Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway

ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6

Regulation of ERK activity duration by Sprouty contributes to dorsoventral patterning

Regulation of anoxic death in Caenorhabditis elegans by mammalian apoptosis signal-regulating kinase (ASK) family proteins

Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling

Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3.

Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon)

Role of the Caenorhabditis elegans Shc adaptor protein in the c-Jun N-terminal kinase signaling pathway

Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction

Roles of MAP kinase cascades in Caenorhabditis elegans

SEK-1 MAPKK mediates Ca2+ signaling to determine neuronal asymmetric development in Caenorhabditis elegans

STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation

Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the inhibitor Sprouty

Signal transduction cascades in axon regeneration: insights from C. elegans

Suppression of PPAR transactivation switches cell fate of bone marrow stem cells from adipocytes into osteoblasts

TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling

TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms

TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation

TAK1 binding protein 2 is essential for liver protection from stressors

TAK1 determines susceptibility to endoplasmic reticulum stress and leptin resistance in the hypothalamus.

TAK1 is a central mediator of NOD2 signaling in epidermal cells

TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.

TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration

TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation

TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signaling

TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway

TDP2 negatively regulates axon regeneration by inducing SUMOylation of an Ets transcription factor