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2B4 but not PD-1 blockade improves mortality in septic animals with preexisting malignancy

artículo científico publicado en 2019

A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria

artículo científico publicado en 2016

A New Safety Event Reporting System Improves Physician Reporting in the Surgical Intensive Care Unit

scientific article published on 01 June 2006

A comparison of critical care research funding and the financial burden of critical illness in the United States

artículo científico publicado en 2012

A venomous relationship: Inflammation, the gut barrier and the STING pathway

scientific article published on 02 April 2019

AGE DISPROPORTIONATELY INCREASES SEPSIS-INDUCED APOPTOSIS IN THE SPLEEN AND GUT EPITHELIUM

article

Abdominal compartment syndrome in a patient resulting from pneumothorax

scientific article published on 17 July 2003

Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways

artículo científico publicado en 2005

Acute Care Nurse Practitioners and Physician Assistants in Critical Care: Transforming Education and Practice

artículo científico publicado en 2017

Adoptive transfer of dying cells causes bystander-induced apoptosis

artículo científico publicado en 2006

Anti-apoptotic peptides protect against radiation-induced cell death

artículo científico publicado en 2007

Antibiotics improve survival and alter the inflammatory profile in a murine model of sepsis from Pseudomonas aeruginosa pneumonia

artículo científico publicado en 2003

Antibiotics improve survival in sepsis independent of injury severity but do not change mortality in mice with markedly elevated interleukin 6 levels

artículo científico publicado en 2004

Application of a Framework to Assess the Usefulness of Alternative Sepsis Criteria

artículo científico publicado en 2016

Attrition of memory CD8 T cells during sepsis requires LFA-1

artículo científico publicado en 2016

Bcl-2 inhibits gut epithelial apoptosis induced by acute lung injury in mice but has no effect on survival

artículo científico publicado en 2003

Breaking the bond between tetranectin and HMGB1 in sepsis

scientific article published on 01 April 2020

CD28 Agonism Improves Survival in Immunologically Experienced Septic Mice via IL-10 Released by Foxp3+ Regulatory T Cells

artículo científico publicado en 2020

CD4+ lymphocytes control gut epithelial apoptosis and mediate survival in sepsis

artículo científico publicado en 2009

CXCR4 blockade decreases CD4+ T cell exhaustion and improves survival in a murine model of polymicrobial sepsis.

artículo científico publicado en 2017

Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis.

artículo científico publicado en 2010

Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock

scholarly article by Pratyusha Mandal et al published 17 July 2018 in Immunity

Cecal ligation and puncture followed by methicillin-resistant Staphylococcus aureus pneumonia increases mortality in mice and blunts production of local and systemic cytokines

artículo científico publicado en 2012

Central venous catheter insertion in septic patients admitted from the emergency department: it is all in the timing*.

artículo científico publicado en 2014

Characterization and modulation of the immunosuppressive phase of sepsis

artículo científico publicado en 2010

Chronic Alcohol Ingestion Delays T Cell Activation and Effector Function in Sepsis

artículo científico publicado en 2016

Chronic Alcohol Ingestion Worsens Survival and Alters Gut Epithelial Apoptosis and Cd8+ T Cell Function after Pseudomonas Aeruginosa Pneumonia-Induced Sepsis

artículo científico publicado en 2018

Chronic alcohol ingestion increases mortality and organ injury in a murine model of septic peritonitis

artículo científico publicado en 2013

Correction to: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

scholarly article by Marcin F Osuchowski et al published October 2018 in Infection

Correction: Chronic Alcohol Ingestion Increases Mortality and Organ Injury in a Murine Model of Septic Peritonitis

artículo científico publicado en 2020

Critical Care Organizations: Building and Integrating Academic Programs

artículo científico publicado en 2017

Critical Care Organizations: Business of Critical Care and Value/Performance Building

artículo científico publicado en 2017

Critical illness and the role of the microbiome

scientific article published on 27 December 2018

Cutting Edge: 2B4-Mediated Coinhibition of CD4+ T Cells Underlies Mortality in Experimental Sepsis.

artículo científico publicado en 2017

Daily bathing with chlorhexidine-based soap and the prevention of Staphylococcus aureus transmission and infection

artículo científico publicado en 2014

Depletion of dendritic cells, but not macrophages, in patients with sepsis

artículo científico publicado en 2002

Differential regulation of tissue thiol-disulfide redox status in a murine model of peritonitis ⬇️

artículo científico publicado el 4 de octubre de 2012

Dying as a Pathway to Death in Sepsis

artículo científico publicado en 2018

Early antibiotic administration but not antibody therapy directed against IL-6 improves survival in septic mice predicted to die on basis of high IL-6 levels.

artículo científico publicado en 2005

Effect of an education program aimed at reducing the occurrence of ventilator-associated pneumonia

artículo científico publicado en 2002

Effect of an education program on decreasing catheter-related bloodstream infections in the surgical intensive care unit

artículo científico publicado en 2002

Effect of chlorhexidine/silver sulfadiazine-impregnated central venous catheters in an intensive care unit with a low blood stream infection rate after implementation of an educational program: a before-after trial.

artículo científico publicado en 2007

Effectiveness of Minocycline and Rifampin vs Chlorhexidine and Silver Sulfadiazine-Impregnated Central Venous Catheters in Preventing Central Line-Associated Bloodstream Infection in a High-Volume Academic Intensive Care Unit: A Before and after Tri

artículo científico publicado en 2015

Effects of age on mortality and antibiotic efficacy in cecal ligation and puncture

artículo científico publicado en 2003

Effects of aging on the immunopathologic response to sepsis.

scientific article published on March 2009

Efficacy and safety of an insulin infusion protocol in a surgical ICU.

artículo científico publicado en 2005

Enterocyte-specific epidermal growth factor prevents barrier dysfunction and improves mortality in murine peritonitis

artículo científico publicado en 2009

Epidemiology of methicillin-resistant Staphylococcus aureus colonization in a surgical intensive care unit

artículo científico publicado en 2006

Epidermal Growth Factor Improves Intestinal Integrity and Survival in Murine Sepsis Following Chronic Alcohol Ingestion

artículo científico publicado en 2016

Epidermal Growth Factor Improves SurvivaL and Prevents Intestinal Injury in a Murine Model of Pseudomonas aeruginosa Pneumonia ⬇️

artículo científico publicado el 1 de octubre de 2011

Epidermal growth factor treatment decreases mortality and is associated with improved gut integrity in sepsis.

artículo científico publicado en 2008

Epithelial cells.

artículo científico publicado en 2005

Erythropoietin in sepsis: a new use for a familiar drug?

artículo científico publicado en 2009

Examination of non-clinical factors affecting tracheostomy practice in an academic surgical intensive care unit*

scientific article published on 01 December 2009

Fecal microbiota transplantation for multiple organ dysfunction syndrome

artículo científico publicado en 2016

Genetic research and testing in critical care: surrogates' perspective

artículo científico publicado en 2006

Getting older can be exhausting

artículo científico publicado en 2014

Gut integrity in critical illness

artículo científico publicado en 2019

High-dose exogenous iron following cecal ligation and puncture increases mortality rate in mice and is associated with an increase in gut epithelial and splenic apoptosis

artículo científico publicado en 2004

ICU and ventilator mortality among critically ill adults with COVID-19

artículo científico publicado en 2020

IL-15 prevents apoptosis, reverses innate and adaptive immune dysfunction, and improves survival in sepsis.

artículo científico publicado en 2009

IL-17, IL-27, and IL-33: A Novel Axis Linked to Immunological Dysfunction During Sepsis

artículo científico publicado en 2019

Immune Checkpoint Inhibition in Sepsis: A Phase 1b Randomized, Placebo-Controlled, Single Ascending Dose Study of Antiprogrammed Cell Death-Ligand 1 Antibody (BMS-936559)

scientific article published on 01 May 2019

Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab

scientific article published on 01 October 2019

Impact of a methicillin-resistant Staphylococcus aureus active surveillance program on contact precaution utilization in a surgical intensive care unit

scientific article published on 01 February 2007

Implementation of a mandatory checklist of protocols and objectives improves compliance with a wide range of evidence-based intensive care unit practices

artículo científico publicado en 2009

Improved extubation rates and earlier liberation from mechanical ventilation with implementation of a daily spontaneous-breathing trial protocol

artículo científico

Increased attrition of memory T cells during sepsis requires 2B4

scientific article published on 02 May 2019

Increased mortality in CD43-deficient mice during sepsis

artículo científico publicado en 2018

Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis

scientific article published on 01 April 2002

Inhibition of intestinal epithelial apoptosis improves survival in a murine model of radiation combined injury

artículo científico publicado en 2013

Innovative Interdisciplinary Strategies to Address the Intensivist Shortage

artículo científico publicado en 2017

Intestinal crosstalk: a new paradigm for understanding the gut as the "motor" of critical illness

artículo científico publicado en 2007

Intestine-Specific Mttp Deletion Decreases Mortality and Prevents Sepsis-Induced Intestinal Injury in a Murine Model of Pseudomonas aeruginosa Pneumonia ⬇️

artículo científico publicado el 8 de noviembre de 2012

Intestine-specific deletion of microsomal triglyceride transfer protein increases mortality in aged mice

artículo científico publicado en 2014

Intestine-specific overexpression of IL-10 improves survival in polymicrobial sepsis.

artículo científico publicado en 2008

Iron dysregulation combined with aging prevents sepsis-induced apoptosis

artículo científico publicado en 2005

Is A Diagnosis of Sepsis Sufficient to Warrant Stress Ulcer Prophylaxis?

artículo científico publicado en 2016

It Was the Best of Rounds, It Was the Worst of Rounds, It Was the Age of Wisdom, It Was the Age of Electronic Health Records…

scientific article published on 01 October 2018

Junctional adhesion molecule-A deletion increases phagocytosis and improves survival in a murine model of sepsis

artículo científico publicado en 2022

Just the right amount of JNK: How nuclear factor-kappaB and downstream mediators prevent burn-induced intestinal injury

artículo científico publicado en 2007

Lymphocyte phenotyping to distinguish septic from nonseptic critical illness.

artículo científico publicado en 2007

Mechanisms of Intestinal Barrier Dysfunction in Sepsis

artículo científico publicado en 2016

Mechanisms of decreased intestinal epithelial proliferation and increased apoptosis in murine acute lung injury

artículo científico publicado en 2005

Mechanisms of methicillin-resistant Staphylococcus aureus pneumonia-induced intestinal epithelial apoptosis

artículo científico publicado en 2012

Metabolic support in the critically ill: a consensus of 19

artículo científico publicado en 2019

Microfluidic amperometric sensor for analysis of nitric oxide in whole blood

artículo científico publicado en 2013

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

scholarly article by Marcin F. Osuchowski et al published 14 August 2018 in Infection

Minimum Quality Threshold in Pre-Clinical Sepsis Studies (Mqtipss): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis

Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

Mitochondrial resuscitation with exogenous cytochrome c in the septic heart

artículo científico publicado en 2007

Mupirocin resistance in patients colonized with methicillin-resistant Staphylococcus aureus in a surgical intensive care unit

artículo científico publicado en 2007

Murine Lung Cancer Increases CD4+ T Cell Apoptosis and Decreases Gut Proliferative Capacity in Sepsis

artículo científico publicado en 2016

Murine lung cancer induces generalized T-cell exhaustion

artículo científico publicado en 2015

Myocardial transcriptional profiles in a murine model of sepsis: evidence for the importance of age.

artículo científico publicado en 2008

Neutrophil depletion causes a fatal defect in murine pulmonary Staphylococcus aureus clearance.

artículo científico publicado en 2008

Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in mice

artículo científico publicado en 2007

New insights into the gut as the driver of critical illness and organ failure

artículo científico publicado en 2017

Organ failure avoidance and mitigation strategies in surgery.

artículo científico

Overexpression of Bcl-2 in the intestinal epithelium improves survival in septic mice

artículo científico publicado en 2002

Part I: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Study Design and Humane Modeling Endpoints

artículo científico publicado en 2019

Pathophysiology of septic shock: From bench to bedside

artículo científico publicado en 2016

Pathophysiology of the Gut and the Microbiome in the Host Response

artículo científico publicado en 2017

Patient safety event reporting in critical care: a study of three intensive care units

artículo científico publicado en 2007

Patient-care time allocation by nurse practitioners and physician assistants in the intensive care unit ⬇️

artículo científico publicado el 15 de febrero de 2012

Patients' and surrogates' perspective on research and testing in critical care

artículo científico publicado en 2007

Pharmacoepidemiology of QT-interval prolonging drug administration in critically ill patients

artículo científico publicado en 2008

Phenotypic T cell exhaustion in a murine model of bacterial infection in the setting of pre-existing malignancy

artículo científico publicado en 2014

Plasticity of the systemic inflammatory response to acute infection during critical illness: development of the riboleukogram

artículo científico publicado en 2008

Pre-existing malignancy results in increased prevalence of distinct populations of CD4+ T cells during sepsis.

artículo científico publicado en 2018

Preexisting malignancy abrogates the beneficial effects of CXCR4 blockade during sepsis

scientific article published on 27 January 2020

Premise for Standardized Sepsis Models

artículo científico publicado en 2019

Prescribing patterns of hydrocortisone in septic shock: a single-center experience of how surviving sepsis guidelines are interpreted and translated into bedside practice

artículo científico publicado en 2013

Prevalence and Impact of Unknown Diabetes in the ICU.

artículo científico publicado en 2015

Prevention of lymphocyte apoptosis in septic mice with cancer increases mortality

artículo científico publicado en 2011

Prevention of lymphocyte apoptosis--a potential treatment of sepsis?

artículo científico publicado en 2005

Regulators of Intestinal Epithelial Migration in Sepsis

artículo científico publicado en 2018

Relationship between tracheostomy timing and duration of mechanical ventilation in critically ill patients

artículo científico publicado en 2005

Retrogenic ICOS Expression Increases Differentiation of KLRG-1hiCD127loCD8+ T Cells during Listeria Infection and Diminishes Recall Responses

artículo científico publicado en 2016

Sepsis erodes CD8+ memory T cell-protective immunity against an EBV homolog in a 2B4-dependent manner

scientific article published on 09 January 2019

Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest*

artículo científico publicado en 2003

Sepsis reveals compartment-specific responses in intestinal proliferation and apoptosis in transgenic mice whose enterocytes re-enter the cell cycle

artículo científico publicado en 2017

Sequence makes a difference: paradoxical effects of stress in vivo

artículo científico publicado en 2004

Staphylococcus aureus nasal colonization and subsequent infection in intensive care unit patients: does methicillin resistance matter?

artículo científico publicado en 2010

Streptococcus pneumoniae and Pseudomonas aeruginosa pneumonia induce distinct host responses

artículo científico publicado en 2010

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.

artículo científico

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.

artículo científico publicado en 2017

TAT-BH4 and TAT-Bcl-xL peptides protect against sepsis-induced lymphocyte apoptosis in vivo

artículo científico publicado en 2006

Targeted delivery of siRNA to cell death proteins in sepsis.

artículo científico publicado en 2009

The Microbiome in Critical Illness: Firm Conclusions or Bact to Square One?

artículo científico publicado en 2016

The New Sepsis Definitions: Implications for the Basic and Translational Research Communities

artículo científico publicado en 2016

The Surviving Sepsis Campaign: Basic/Translational Science Research Priorities

artículo científico publicado en 2020

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

artículo científico publicado en 2016

The authors reply

artículo científico publicado en 2019

The endogenous bacteria alter gut epithelial apoptosis and decrease mortality following Pseudomonas aeruginosa pneumonia

artículo científico publicado en 2012

The gut microbiome alters immunophenotype and survival from sepsis

scientific article published on 15 July 2019

The impact of a simple, low-cost oral care protocol on ventilator-associated pneumonia rates in a surgical intensive care unit

artículo científico publicado en 2009

The impact of bedside behavior on catheter-related bacteremia in the intensive care unit.

artículo científico publicado en 2004

The intestinal microenvironment in sepsis

artículo científico publicado en 2017

The role of heat shock protein 70 in mediating age-dependent mortality in sepsis

artículo científico publicado en 2011

The sepsis seesaw: tilting toward immunosuppression

artículo científico publicado en 2009

The small heat shock protein HSPB1 protects mice from sepsis

scientific article published in Scientific Reports

The surviving sepsis campaign: basic/translational science research priorities

artículo científico publicado en 2020

The systemic inflammatory response syndrome

artículo científico publicado en 2006

The turn team: a novel strategy for reducing pressure ulcers in the surgical intensive care unit

artículo científico publicado en 2013

Tracheostomy protocol: experience with development and potential utility

artículo científico publicado en 2008

Treatment of hypophosphatemia using a protocol based on patient weight and serum phosphorus level in a surgical intensive care unit.

artículo científico publicado en 2004

Use of hypochlorite solution to decrease rates of Clostridium difficile-associated diarrhea

artículo científico publicado en 2007

Using Incentives to Improve Resource Utilization: A Quasi-Experimental Evaluation of an ICU Quality Improvement Program

artículo científico publicado en 2015

Workforce, Workload, and Burnout Among Intensivists and Advanced Practice Providers: A Narrative Review

artículo científico publicado en 2019

Workforce, Workload, and Burnout in Critical Care Organizations: Survey Results and Research Agenda

scientific article published on 11 August 2020

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