Lista de obras -

A dual-acting 5-HT6 receptor inverse agonist/MAO-B inhibitor displays glioprotective and pro-cognitive properties

scientific article published on 22 August 2020

A new cytotoxic triterpene saponin from Lysimachia nummularia L.

artículo científico publicado en 2013

Analgesic and antiallodynic activity of novel anticonvulsant agents derived from 3-benzhydryl-pyrrolidine-2,5-dione in mouse models of nociceptive and neuropathic pain

artículo científico publicado en 2019

Analgesic, antiallodynic, and anticonvulsant activity of novel hybrid molecules derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butanamide in animal models of pain and epilepsy

artículo científico publicado en 2017

Anti-Helicobacter pylori activities of selected N-substituted cinnamamide derivatives evaluated on reference and clinical bacterial strains

artículo científico publicado en 2018

Antiallodynic and antihyperalgesic activity of new 3,3-diphenyl-propionamides with anticonvulsant activity in models of pain in mice.

artículo científico publicado en 2017

Anticonvulsant activity, crystal structures, and preliminary safety evaluation of N-trans-cinnamoyl derivatives of selected (un)modified aminoalkanols.

artículo científico publicado en 2015

Apigenin inhibits TGF-β1 induced fibroblast-to-myofibroblast transition in human lung fibroblast populations

artículo científico publicado en 2013

Autophagy modulating agents as chemosensitizers for cisplatin therapy in cancer

artículo científico publicado en 2020

Characteristics of metabolic stability and the cell permeability of 2-pyrimidinyl-piperazinyl-alkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione with antidepressant- and anxiolytic-like activities

scientific article published on 04 December 2018

Chemopreventive and Anticancer Activities of Bacopa monnieri Extracted from Artificial Digestive Juices

scientific article published on 01 March 2017

Connective tissue growth factor regulates transition of primary bronchial fibroblasts to myofibroblasts in asthmatic subjects

artículo científico publicado en 2017

Correction to: Fibroblast-to-myofibroblast transition in bronchial asthma

artículo científico publicado en 2019

Design, synthesis and anticonvulsant-analgesic activity of new -[(phenoxy)alkyl]- and -[(phenoxy)ethoxyethyl]aminoalkanols

scientific article published on 11 November 2016

Discovery of Novel UV-Filters with Favorable Safety Profiles in the 5-Arylideneimidazolidine-2,4-dione Derivatives Group

scientific article published on 24 June 2019

Dual 5-HT6 and D3 Receptor Antagonists in a Group of 1H-Pyrrolo[3,2-c]quinolines with Neuroprotective and Procognitive Activity

scientific article published on 02 April 2019

Fibroblast-to-myofibroblast transition in bronchial asthma

scientific article published on 12 August 2018

Growth and motility of human skin fibroblasts on multilayer strong polyelectrolyte films

artículo científico publicado en 2015

High bisphenol A concentrations augment the invasiveness of tumor cells through Snail-1/Cx43/ERRγ-dependent epithelial-mesenchymal transition

scientific article published on 17 October 2019

Impact of N-Alkylamino Substituents on Serotonin Receptor (5-HTR) Affinity and Phosphodiesterase 10A (PDE10A) Inhibition of Isoindole-1,3-dione Derivatives

artículo científico publicado en 2020

Lclet 4 enhances pro-apoptotic and anti-invasive effects of mitoxantrone on human prostate cancer cells - in vitro study

artículo científico publicado en 2013

Metabolic carbonyl reduction of anthracyclines - role in cardiotoxicity and cancer resistance. Reducing enzymes as putative targets for novel cardioprotective and chemosensitizing agents.

artículo científico publicado en 2017

Metabolic stability and its role in the discovery of new chemical entities

scientific article published on 01 September 2019

Microbial biotransformation of some novel hydantoin derivatives: Perspectives for bioremediation of potential sunscreen agents

scientific article published on 29 May 2019

Minor triterpene saponins from underground parts of Lysimachia thyrsiflora: structure elucidation, LC-ESI-MS/MS quantification, and biological activity

artículo científico publicado en 2013

Multidirectional effects of triterpene saponins on cancer cells - mini-review of in vitro studies

artículo científico publicado en 2015

Novel non-sulfonamide 5-HT6 receptor partial inverse agonist in a group of imidazo[4,5-b]pyridines with cognition enhancing properties.

artículo científico publicado en 2017

Novel phosphodiesterases inhibitors from the group of purine-2,6-dione derivatives as potent modulators of airway smooth muscle cell remodelling

scientific article published on 06 November 2019

Pentoxifylline and its active metabolite lisofylline attenuate transforming growth factor β1-induced asthmatic bronchial fibroblast-to-myofibroblast transition

artículo científico publicado en 2016

Photostability of Terbinafine Under UVA Irradiation: The Effect of UV Absorbers

artículo científico publicado en 2019

Piperlongumine (piplartine) as a lead compound for anticancer agents - Synthesis and properties of analogues: A mini-review

artículo científico publicado en 2018

STUDIES OF NEW PURINE DERIVATIVES WITH ACETIC ACID MOIETY IN HUMAN KERATINOCYTES.

artículo científico publicado en 2017

Saponins as chemosensitizing substances that improve effectiveness and selectivity of anticancer drug-Minireview of in vitro studies

scientific article published on 11 July 2019

Similar Safety Profile of the Enantiomeric N-Aminoalkyl Derivatives of Trans-2-Aminocyclohexan-1-ol Demonstrating Anticonvulsant Activity

scientific article published on 09 July 2019

Synergistic Cytotoxic and Anti-invasive Effects of Mitoxantrone and Triterpene Saponins from Lysimachia ciliata on Human Prostate Cancer Cells

artículo científico publicado en 2016

Synergistic anticancer activity of doxorubicin and piperlongumine on DU-145 prostate cancer cells - The involvement of carbonyl reductase 1 inhibition

artículo científico publicado en 2019

Synthesis and Determination of Lipophilicity, Anticonvulsant Activity, and Preliminary Safety of 3-Substituted and 3-Unsubstituted N-[(4-Arylpiperazin-1-yl)alkyl]pyrrolidine-2,5-dione Derivatives.

artículo científico publicado en 2017

Synthesis and Pharmacological Evaluation of Novel Silodosin-Based Arylsulfonamide Derivatives as α/α-Adrenergic Receptor Antagonist with Potential Uroselective Profile

artículo científico publicado en 2018

Synthesis and anticonvulsant activity of phenoxyacetyl derivatives of amines, including aminoalkanols and amino acids

scientific article published on 19 October 2018

Synthesis of N ‐(phenoxyalkyl)‐, N ‐{2‐[2‐(phenoxy)ethoxy]ethyl}‐ or N ‐(phenoxyacetyl)piperazine Derivatives and Their Activity Within the Central Nervous System

artículo científico publicado en 2019

Synthesis of strong polycations with improved biological properties.

artículo científico publicado en 2013

The impact of ZnO and TiO2 on the stability of clotrimazole under UVA irradiation: Identification of photocatalytic degradation products and in vitro cytotoxicity assessment.

artículo científico publicado en 2017

Transforming growth factor-β₁-induced expression of connective tissue growth factor is enhanced in bronchial fibroblasts derived from asthmatic patients

artículo científico publicado en 2012

Triterpene saponosides from Lysimachia ciliata differentially attenuate invasive potential of prostate cancer cells

artículo científico publicado en 2013

Usnic acid and atranorin exert selective cytostatic and anti-invasive effects on human prostate and melanoma cancer cells

artículo científico publicado en 2017

Usnic acid reactive metabolites formation in human, rat, and mice microsomes. Implication for hepatotoxicity

artículo científico publicado en 2018

Lista de obras de

A dual-acting 5-HT6 receptor inverse agonist/MAO-B inhibitor displays glioprotective and pro-cognitive properties

A new cytotoxic triterpene saponin from Lysimachia nummularia L.

Analgesic and antiallodynic activity of novel anticonvulsant agents derived from 3-benzhydryl-pyrrolidine-2,5-dione in mouse models of nociceptive and neuropathic pain

Analgesic, antiallodynic, and anticonvulsant activity of novel hybrid molecules derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butanamide in animal models of pain and epilepsy

Anti-Helicobacter pylori activities of selected N-substituted cinnamamide derivatives evaluated on reference and clinical bacterial strains

Antiallodynic and antihyperalgesic activity of new 3,3-diphenyl-propionamides with anticonvulsant activity in models of pain in mice.

Anticonvulsant activity, crystal structures, and preliminary safety evaluation of N-trans-cinnamoyl derivatives of selected (un)modified aminoalkanols.

Apigenin inhibits TGF-β1 induced fibroblast-to-myofibroblast transition in human lung fibroblast populations

Autophagy modulating agents as chemosensitizers for cisplatin therapy in cancer

Characteristics of metabolic stability and the cell permeability of 2-pyrimidinyl-piperazinyl-alkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione with antidepressant- and anxiolytic-like activities

Chemopreventive and Anticancer Activities of Bacopa monnieri Extracted from Artificial Digestive Juices

Connective tissue growth factor regulates transition of primary bronchial fibroblasts to myofibroblasts in asthmatic subjects

Correction to: Fibroblast-to-myofibroblast transition in bronchial asthma

Design, synthesis and anticonvulsant-analgesic activity of new -[(phenoxy)alkyl]- and -[(phenoxy)ethoxyethyl]aminoalkanols

Discovery of Novel UV-Filters with Favorable Safety Profiles in the 5-Arylideneimidazolidine-2,4-dione Derivatives Group

Dual 5-HT6 and D3 Receptor Antagonists in a Group of 1H-Pyrrolo[3,2-c]quinolines with Neuroprotective and Procognitive Activity

Fibroblast-to-myofibroblast transition in bronchial asthma

Growth and motility of human skin fibroblasts on multilayer strong polyelectrolyte films

High bisphenol A concentrations augment the invasiveness of tumor cells through Snail-1/Cx43/ERRγ-dependent epithelial-mesenchymal transition

Impact of N-Alkylamino Substituents on Serotonin Receptor (5-HTR) Affinity and Phosphodiesterase 10A (PDE10A) Inhibition of Isoindole-1,3-dione Derivatives

Lclet 4 enhances pro-apoptotic and anti-invasive effects of mitoxantrone on human prostate cancer cells - in vitro study

Metabolic carbonyl reduction of anthracyclines - role in cardiotoxicity and cancer resistance. Reducing enzymes as putative targets for novel cardioprotective and chemosensitizing agents.

Metabolic stability and its role in the discovery of new chemical entities

Microbial biotransformation of some novel hydantoin derivatives: Perspectives for bioremediation of potential sunscreen agents

Minor triterpene saponins from underground parts of Lysimachia thyrsiflora: structure elucidation, LC-ESI-MS/MS quantification, and biological activity

Multidirectional effects of triterpene saponins on cancer cells - mini-review of in vitro studies

Novel non-sulfonamide 5-HT6 receptor partial inverse agonist in a group of imidazo[4,5-b]pyridines with cognition enhancing properties.

Novel phosphodiesterases inhibitors from the group of purine-2,6-dione derivatives as potent modulators of airway smooth muscle cell remodelling

Pentoxifylline and its active metabolite lisofylline attenuate transforming growth factor β1-induced asthmatic bronchial fibroblast-to-myofibroblast transition

Photostability of Terbinafine Under UVA Irradiation: The Effect of UV Absorbers

Piperlongumine (piplartine) as a lead compound for anticancer agents - Synthesis and properties of analogues: A mini-review

STUDIES OF NEW PURINE DERIVATIVES WITH ACETIC ACID MOIETY IN HUMAN KERATINOCYTES.

Saponins as chemosensitizing substances that improve effectiveness and selectivity of anticancer drug-Minireview of in vitro studies

Similar Safety Profile of the Enantiomeric N-Aminoalkyl Derivatives of Trans-2-Aminocyclohexan-1-ol Demonstrating Anticonvulsant Activity

Synergistic Cytotoxic and Anti-invasive Effects of Mitoxantrone and Triterpene Saponins from Lysimachia ciliata on Human Prostate Cancer Cells

Synergistic anticancer activity of doxorubicin and piperlongumine on DU-145 prostate cancer cells - The involvement of carbonyl reductase 1 inhibition

Synthesis and Determination of Lipophilicity, Anticonvulsant Activity, and Preliminary Safety of 3-Substituted and 3-Unsubstituted N-[(4-Arylpiperazin-1-yl)alkyl]pyrrolidine-2,5-dione Derivatives.

Synthesis and Pharmacological Evaluation of Novel Silodosin-Based Arylsulfonamide Derivatives as α/α-Adrenergic Receptor Antagonist with Potential Uroselective Profile

Synthesis and anticonvulsant activity of phenoxyacetyl derivatives of amines, including aminoalkanols and amino acids

Synthesis of N ‐(phenoxyalkyl)‐, N ‐{2‐[2‐(phenoxy)ethoxy]ethyl}‐ or N ‐(phenoxyacetyl)piperazine Derivatives and Their Activity Within the Central Nervous System

Synthesis of strong polycations with improved biological properties.

The impact of ZnO and TiO2 on the stability of clotrimazole under UVA irradiation: Identification of photocatalytic degradation products and in vitro cytotoxicity assessment.

Transforming growth factor-β₁-induced expression of connective tissue growth factor is enhanced in bronchial fibroblasts derived from asthmatic patients

Triterpene saponosides from Lysimachia ciliata differentially attenuate invasive potential of prostate cancer cells

Usnic acid and atranorin exert selective cytostatic and anti-invasive effects on human prostate and melanoma cancer cells

Usnic acid reactive metabolites formation in human, rat, and mice microsomes. Implication for hepatotoxicity