Lista de obras -

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

artículo científico publicado en 2018

A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning

artículo científico publicado en 2009

Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration ⬇️

artículo científico publicado el 29 de noviembre de 2011

Activation of the genetically defined m1 muscarinic receptor potentiates N -methyl- d -aspartate (NMDA) receptor currents in hippocampal pyramidal cells ⬇️

artículo científico publicado el 15 de septiembre de 1998

Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction

artículo científico publicado en 2011

Alzheimer's disease: A clinical perspective and future nonhuman primate research opportunities

scientific article published on 23 December 2019

An Exploration of Subgroups of Mild Cognitive Impairment Based On Cognitive, Neuropsychiatric and Functional Features: Analysis of Data From the National Alzheimer's Coordinating Center ⬇️

artículo científico publicado el 1 de noviembre de 2011

Analysis of shared heritability in common disorders of the brain

artículo científico publicado en 2018

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

artículo científico publicado en 2012

Asparaginyl endopeptidase cleaves TDP‐43 in brain ⬇️

artículo científico publicado el 1 de agosto de 2012

Assessment of cholesterol homeostasis in the living human brain

artículo científico publicado en 2022

Association between polychlorinated biphenyls and Parkinson's disease neuropathology

artículo científico publicado en 2012

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

artículo científico publicado en 2012

Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue

artículo científico publicado en 2021

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Brain microRNAs are associated with variation in cognitive trajectory in advanced age

artículo científico publicado en 2022

Brain proteome-wide association study implicates novel proteins in depression pathogenesis

artículo científico publicado en 2021

Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain

artículo científico publicado en 2022

Cloning and Localization of Exon 5‐Containing Isoforms of the NMDAR1 Subunit in Human and Rat Brains ⬇️

artículo científico publicado el 1 de agosto de 1997

Cloning of M-calpain 80 kD subunit from the axonal degeneration-resistant WLDs mouse mutant ⬇️

artículo científico publicado el 15 de junio de 1998

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

artículo científico publicado en 2010

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

artículo científico publicado en 2011

Comparative distribution of protein components of the A20 ubiquitin-editing complex in normal human brain ⬇️

artículo científico publicado el 23 de mayo de 2012

Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases

artículo científico publicado en 2017

Differential effects of allosteric M(1) muscarinic acetylcholine receptor agonists on receptor activation, arrestin 3 recruitment, and receptor downregulation

artículo científico publicado en 2010

Differential expression of D1 and D2 dopamine and m4 muscarinic acetylcholine receptor proteins in identified striatonigral neurons ⬇️

artículo científico publicado el 1 de diciembre de 1997

Differential presynaptic and postsynaptic expression of m1–m4 muscarinic acetylcholine receptors at the perforant pathway/granule cell synapse ⬇️

artículo científico publicado el 1 de septiembre de 1998

Disease-Modifying Effects of M1 Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model

artículo científico publicado en 2017

Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice ⬇️

artículo científico publicado el 25 de noviembre de 1997

Distribution and Developmental Regulation of Metabotropic Glutamate Receptor 7a in Rat Brain ⬇️

artículo científico publicado el 1 de agosto de 1998

Distribution of muscarinic cholinergic receptor proteins m1 to m4 in area 17 of normal and monocularly deprived rhesus monkeys ⬇️

artículo científico publicado el 10 de noviembre de 1997

Dopamine Axon Varicosities in the Prelimbic Division of the Rat Prefrontal Cortex Exhibit Sparse Immunoreactivity for the Dopamine Transporter ⬇️

artículo científico publicado el 1 de abril de 1998

Dopaminergic Neurons Intrinsic to the Primate Striatum ⬇️

artículo científico publicado el 1 de septiembre de 1997

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

artículo científico publicado en 2014

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

artículo científico publicado en 2012

Feedforward prediction error signals during episodic memory retrieval

artículo científico publicado en 2020

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

artículo científico publicado en 2019

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

scientific journal article

Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease

artículo científico publicado en 2020

Infracortical interstitial cells concurrently expressing m2-muscarinic receptors, acetylcholinesterase and nicotinamide adenine dinucleotide phosphate-diaphorase in the human and monkey cerebral cortex ⬇️

artículo científico publicado el 1 de junio de 1998

Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease

artículo científico publicado en 2020

Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis

scientific article published on 28 January 2021

Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level

artículo científico publicado en 2022

Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

artículo científico publicado en 2020

Late-Life Depression as a Risk Factor for Mild Cognitive Impairment or Alzheimer's Disease in 30 US Alzheimer's Disease Centers ⬇️

artículo científico publicado el 1 de enero de 2012

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.

artículo científico publicado en 2019

Localization of the m2 muscarinic acetylcholine receptor protein and mRNA in cortical neurons of the normal and cholinergically deafferented rhesus monkey ⬇️

artículo científico publicado el 5 de enero de 1998

Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice

artículo científico publicado en 2017

Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

artículo científico publicado en 2015

Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease

scientific article published on 07 August 2020

Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease

scientific article published on 27 August 2019

Neurocognitive correlates of nocturnal oxygen desaturation in a memory clinic population ⬇️

artículo científico publicado el 10 de enero de 2012

Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling ⬇️

artículo científico publicado el 16 de abril de 2012

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis ⬇️

artículo científico publicado en 2020

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

artículo científico publicado en 2012

Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats.

artículo científico publicado en 2008

Paraoxonase-1 polymorphisms in Alzheimer's disease, Parkinson's disease, and AD-PD spectrum diseases ⬇️

artículo científico publicado el 13 de octubre de 2010

Phosphoproteomic Analysis Reveals Site-Specific Changes in GFAP and NDRG2 Phosphorylation in Frontotemporal Lobar Degeneration ⬇️

artículo científico publicado el 22 de octubre de 2010

Polarized Expression of the Antidepressant-Sensitive Serotonin Transporter in Epinephrine-Synthesizing Chromaffin Cells of the Rat Adrenal Gland ⬇️

artículo científico publicado el 1 de enero de 1997

Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain

artículo científico publicado en 2020

Quantitative Analysis of the Detergent-Insoluble Brain Proteome in Frontotemporal Lobar Degeneration Using SILAC Internal Standards ⬇️

artículo científico publicado el 4 de abril de 2012

RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells

artículo científico publicado en 2013

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

artículo científico publicado en 2017

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

artículo científico publicado en 2015

Reply: LATE to the PART-y

artículo científico publicado en 2019

Rho Kinase II Phosphorylation of the Lipoprotein Receptor LR11/SORLA Alters Amyloid-β Production ⬇️

artículo científico publicado el 8 de diciembre de 2010

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis ⬇️

artículo científico publicado el 1 de julio de 1995

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

artículo científico publicado en 2009

Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain

artículo científico publicado en 2020

Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra ⬇️

artículo científico publicado el 17 de noviembre de 1997

Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau

artículo científico publicado en 2020

TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions

artículo científico publicado en 2014

TREM2 is associated with increased risk for Alzheimer's disease in African Americans

artículo científico publicado en 2015

The physician-scientist, 75 years after Vannevar Bush-rethinking the 'bench' and 'bedside' dichotomy

scientific article published on 09 April 2020

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

article

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

artículo científico publicado en 2016

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

artículo científico publicado en 2013

White matter hyperintensities and changes in white matter integrity in patients with Alzheimer’s disease ⬇️

artículo científico publicado el 9 de diciembre de 2010

m2 muscarinic acetylcholine receptor-immunoreactive neurons are not reduced within the nucleus basalis in Alzheimer's disease: Relationship with cholinergic and galaninergic perikarya ⬇️

artículo científico publicado el 16 de marzo de 1998

β-Hexachlorocyclohexane levels in serum and risk of Parkinson's disease ⬇️

artículo científico publicado el 17 de mayo de 2011

Lista de obras de

18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning

Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration ⬇️

Activation of the genetically defined m1 muscarinic receptor potentiates N -methyl- d -aspartate (NMDA) receptor currents in hippocampal pyramidal cells ⬇️

Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction

Alzheimer's disease: A clinical perspective and future nonhuman primate research opportunities

An Exploration of Subgroups of Mild Cognitive Impairment Based On Cognitive, Neuropsychiatric and Functional Features: Analysis of Data From the National Alzheimer's Coordinating Center ⬇️

Analysis of shared heritability in common disorders of the brain

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

Asparaginyl endopeptidase cleaves TDP‐43 in brain ⬇️

Assessment of cholesterol homeostasis in the living human brain

Association between polychlorinated biphenyls and Parkinson's disease neuropathology

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Brain microRNAs are associated with variation in cognitive trajectory in advanced age

Brain proteome-wide association study implicates novel proteins in depression pathogenesis

Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain

Cloning and Localization of Exon 5‐Containing Isoforms of the NMDAR1 Subunit in Human and Rat Brains ⬇️

Cloning of M-calpain 80 kD subunit from the axonal degeneration-resistant WLDs mouse mutant ⬇️

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Comparative distribution of protein components of the A20 ubiquitin-editing complex in normal human brain ⬇️

Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases

Differential effects of allosteric M(1) muscarinic acetylcholine receptor agonists on receptor activation, arrestin 3 recruitment, and receptor downregulation

Differential expression of D1 and D2 dopamine and m4 muscarinic acetylcholine receptor proteins in identified striatonigral neurons ⬇️

Differential presynaptic and postsynaptic expression of m1–m4 muscarinic acetylcholine receptors at the perforant pathway/granule cell synapse ⬇️

Disease-Modifying Effects of M1 Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model

Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice ⬇️

Distribution and Developmental Regulation of Metabotropic Glutamate Receptor 7a in Rat Brain ⬇️

Distribution of muscarinic cholinergic receptor proteins m1 to m4 in area 17 of normal and monocularly deprived rhesus monkeys ⬇️

Dopamine Axon Varicosities in the Prelimbic Division of the Rat Prefrontal Cortex Exhibit Sparse Immunoreactivity for the Dopamine Transporter ⬇️

Dopaminergic Neurons Intrinsic to the Primate Striatum ⬇️

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

Feedforward prediction error signals during episodic memory retrieval

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease

Infracortical interstitial cells concurrently expressing m2-muscarinic receptors, acetylcholinesterase and nicotinamide adenine dinucleotide phosphate-diaphorase in the human and monkey cerebral cortex ⬇️

Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease

Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis

Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level

Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

Late-Life Depression as a Risk Factor for Mild Cognitive Impairment or Alzheimer's Disease in 30 US Alzheimer's Disease Centers ⬇️

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.

Localization of the m2 muscarinic acetylcholine receptor protein and mRNA in cortical neurons of the normal and cholinergically deafferented rhesus monkey ⬇️

Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice

Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease

Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease

Neurocognitive correlates of nocturnal oxygen desaturation in a memory clinic population ⬇️

Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling ⬇️

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis ⬇️

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats.

Paraoxonase-1 polymorphisms in Alzheimer's disease, Parkinson's disease, and AD-PD spectrum diseases ⬇️

Phosphoproteomic Analysis Reveals Site-Specific Changes in GFAP and NDRG2 Phosphorylation in Frontotemporal Lobar Degeneration ⬇️

Polarized Expression of the Antidepressant-Sensitive Serotonin Transporter in Epinephrine-Synthesizing Chromaffin Cells of the Rat Adrenal Gland ⬇️

Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain

Quantitative Analysis of the Detergent-Insoluble Brain Proteome in Frontotemporal Lobar Degeneration Using SILAC Internal Standards ⬇️

RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

Reply: LATE to the PART-y

Rho Kinase II Phosphorylation of the Lipoprotein Receptor LR11/SORLA Alters Amyloid-β Production ⬇️

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis ⬇️

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain

Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra ⬇️

Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau

TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions

TREM2 is associated with increased risk for Alzheimer's disease in African Americans

The physician-scientist, 75 years after Vannevar Bush-rethinking the 'bench' and 'bedside' dichotomy

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

White matter hyperintensities and changes in white matter integrity in patients with Alzheimer’s disease ⬇️

m2 muscarinic acetylcholine receptor-immunoreactive neurons are not reduced within the nucleus basalis in Alzheimer's disease: Relationship with cholinergic and galaninergic perikarya ⬇️