Lista de obras -

A Phase II study of the sterilising activities of ofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis

artículo científico publicado en 2008

A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis

scientific article published on 05 November 2018

A rapid and sensitive HPLC–MS method for the detection of plasma and cellular rifampicin

scientific article published on 10 July 2007

Accelerating the transition of new tuberculosis drug combinations from Phase II to Phase III trials: New technologies and innovative designs

scientific article published on 09 July 2019

Adaptive clinical trials in tuberculosis: applications, challenges and solutions

artículo científico

Adequacy of Rifampin Absorption after Jejunostomy Tube Administration.

artículo científico publicado en 2016

Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia (ARREST): study protocol for a randomised controlled trial

artículo científico publicado en 2012

An integrated model of care for neurological infections: the first six years of referrals to a specialist service at a university teaching hospital in Northwest England

artículo científico publicado en 2015

Assessment of the Efficacy of New Anti-Tuberculosis Drugs

artículo científico publicado en 2008

Association of variants within the GST and other genes with anti-tubercular agents related toxicity: a systematic review and meta-analysis

article

Bedaquiline kills persistent Mycobacterium tuberculosis with no disease relapse: an in vivo model of a potential cure

scientific article published on 01 June 2019

Biomarkers for tuberculosis disease activity, cure, and relapse

artículo científico publicado en 2010

Bridging the gap in the fight against tuberculosis

artículo científico publicado en 2013

CYP genetic variants and toxicity related to anti-tubercular agents: a systematic review and meta-analysis

article

Comparing the efficacy of drug regimens for pulmonary tuberculosis: meta-analysis of endpoints in early phase clinical trials

artículo científico publicado en 2017

Coping with Africa's increasing tuberculosis burden: are community supervisors an essential component of the DOT strategy? Directly observed therapy

artículo científico publicado en 1997

Delivery of long-term-injectable agents for TB by lay carers: pragmatic randomised trial

scientific article published on 01 November 2019

Directly observed therapy for tuberculosis in rural South Africa, 1991 through 1994

article

Doubts about DOTS.

artículo científico publicado en 2008

Early clinical development of anti-tuberculosis drugs: science, statistics and sterilizing activity

artículo científico publicado en 2010

Effects of dosage, comorbidities, and food on isoniazid pharmacokinetics in Peruvian tuberculosis patients

artículo científico publicado en 2014

Efficacy and Safety of High-Dose Rifampin in Pulmonary Tuberculosis. A Randomized Controlled Trial

artículo científico publicado en 2018

Efficacy of twice weekly treatment for tuberculosis given under direct observation in Africa

artículo científico publicado en 1997

Emergence of multidrug-resistant tuberculosis in a community-based directly observed treatment programme in rural South Africa.

artículo científico publicado en 1999

Evaluation of high-dose rifampin in patients with new, smear-positive tuberculosis (HIRIF): study protocol for a randomized controlled trial

artículo científico publicado en 2016

Evaluation of new antituberculosis drugs in mouse models

artículo científico publicado en 2007

Fluoroquinolones for treating tuberculosis (presumed drug-sensitive)

artículo científico publicado en 2013

Frequency of functional drug disposition gene polymorphism in Thai population: relevance to antiretroviral drugs

article

Genetic Determinants of the Pharmacokinetic Variability of Rifampin in Malawian Adults with Pulmonary Tuberculosis

artículo científico publicado en 2017

HIV and tuberculosis

scientific article published on 01 January 1996

High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

artículo científico publicado en 2011

Impact of the human immunodeficiency virus epidemic on mortality among adults with tuberculosis in rural South Africa, 1991-1995.

artículo científico publicado en 1998

Importance of collection tube during clinical studies of oseltamivir

artículo científico publicado en 2007

In routine UK hospital practice T-SPOT.TB™ is useful in some patients with a modest pre-test probability of active tuberculosis.

artículo científico publicado en 2012

Influence of genetic variants on toxicity to anti-tubercular agents: a systematic review and meta-analysis (protocol)

artículo científico publicado en 2017

Insufficient evidence for chest CT scan in TB outbreak investigation.

artículo científico publicado en 2010

Intra-individual effects of food upon the pharmacokinetics of rifampicin and isoniazid

artículo científico publicado en 2019

Intrapulmonary pharmacokinetics of first-line anti-TB drugs in Malawian tuberculosis patients

artículo científico publicado en 2020

Investigation of Elimination Rate, Persistent Subpopulation Removal, and Relapse Rates of Mycobacterium tuberculosis by Using Combinations of First-Line Drugs in a Modified Cornell Mouse Model

artículo científico publicado en 2016

Isoniazid activity is terminated by bacterial persistence

scientific article published on 01 June 2007

Kinetics of Mycobacterium tuberculosis-specific IFN-γ responses and sputum bacillary clearance in HIV-infected adults during treatment of pulmonary tuberculosis

artículo científico publicado en 2015

Linezolid pharmacokinetics in MDR-TB: a systematic review, meta-analysis and Monte Carlo simulation.

artículo científico publicado en 2018

Longitudinal Pharmacokinetic-Pharmacodynamic Biomarkers Correlate With Treatment Outcome in Drug-Sensitive Pulmonary Tuberculosis: A Population Pharmacokinetic-Pharmacodynamic Analysis

artículo científico publicado en 2020

Making up the difference: ensuring the bioequivalence of fixed-dose combinations for tuberculosis

artículo científico publicado en 2018

Methods for selecting regimen duration to prevent relapse in drug-susceptible and drug-resistant TB.

artículo científico publicado en 2016

Mixture analysis of tuberculin survey data from northern Malawi and critique of the method.

artículo científico publicado en 2006

Model-Based Relationship between the Molecular Bacterial Load Assay and Time to Positivity in Liquid Culture

scientific article published on 23 September 2019

Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in rural Africa

artículo científico publicado en 1997

Mouse models of Japanese encephalitis virus infection: A systematic review and meta-analysis using a meta-regression approach

artículo científico publicado en 2022

Moxifloxacin replacement in contemporary tuberculosis drug regimens is ineffective against persistent Mycobacterium tuberculosis: Novel insights from the Cornell mouse model.

artículo científico publicado en 2018

Opinion: the pharmacometrics of infectious disease

artículo científico publicado en 2013

Optimal doses of rifampicin in the standard drug regimen to shorten tuberculosis treatment duration and reduce relapse by eradicating persistent bacteria

artículo científico publicado en 2017

Optimal sampling strategies for early pharmacodynamic measures in tuberculosis

artículo científico publicado en 2006

Optimising molecular diagnostic capacity for effective control of tuberculosis in high-burden settings

artículo científico publicado en 2016

Optimizing outpatient serial sputum colony counting for studies of tuberculosis treatment in resource-poor settings

artículo científico publicado en 2012

Pediatric tuberculosis in rural South Africa--value of directly observed therapy

artículo científico publicado en 1998

Perceptions of Research Bronchoscopy in Malawian Adults with Pulmonary Tuberculosis: A Cross-Sectional Study

artículo científico publicado en 2016

Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis

artículo científico publicado en 2015

Pharmacokinetics and pharmacodynamics in the development of anti-tuberculosis drugs

artículo científico publicado en 2008

Pharmacokinetics of anti-TB drugs in Malawian children: reconsidering the role of ethambutol

artículo científico publicado en 2015

Pharmacokinetics of co-formulated mefloquine and artesunate in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum infection in Burkina Faso

artículo científico publicado en 2014

Pharmacokinetics of rifampin in Peruvian tuberculosis patients with and without comorbid diabetes or HIV

artículo científico publicado en 2012

Pharmacologic considerations in use and development of antituberculosis drugs

artículo científico publicado en 2014

Poor outcomes in recurrent tuberculosis: More than just drug resistance?

artículo científico publicado en 2019

Population pharmacokinetic modelling of once-daily ritonavir-boosted darunavir in HIV-infected patients.

artículo científico publicado en 2010

Population pharmacokinetics of ritonavir-boosted atazanavir in HIV-infected patients and healthy volunteers

artículo científico publicado en 2009

Protocol for the development of the STrengthening the Reporting Of Pharmacogenetic Studies (STROPS) guideline: checklist of items for reporting pharmacogenetic studies

scientific article published on 11 July 2019

Publisher Correction: A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis

scientific article published on 01 January 2019

Rapid degradation of oseltamivir phosphate in clinical samples by plasma esterases

artículo científico publicado en 2006

Re-growth of Mycobacterium tuberculosis populations exposed to antibiotic combinations is due to the presence of isoniazid and not bacterial growth rate

artículo científico publicado en 2019

Recent advances in tuberculosis: New drugs and treatment regimens.

artículo científico publicado en 2013

Reply to "adequate design of pharmacokinetic-pharmacodynamic studies will help optimize tuberculosis treatment for the future".

artículo científico publicado en 2015

Reply to te Brake : Conflicting Findings on an Intermediate Dose of Rifampicin for Pulmonary Tuberculosis

artículo científico publicado en 2019

Reported outcomes in phase II studies of newly-diagnosed pulmonary tuberculosis

artículo científico publicado en 2015

Resistance to antituberculosis drugs in rural South Africa: rates, patterns, risks, and transmission dynamics

artículo científico publicado en 1996

STrengthening the Reporting Of Pharmacogenetic Studies: Development of the STROPS guideline

scientific article published on 21 September 2020

Sales of over-the-counter remedies as an early warning system for winter bed crises ⬇️

artículo científico publicado el 1 de agosto de 2003

Sequential population pharmacokinetic modeling of lopinavir and ritonavir in healthy volunteers and assessment of different dosing strategies

artículo científico publicado en 2011

Serial image analysis of Mycobacterium tuberculosis colony growth reveals a persistent subpopulation in sputum during treatment of pulmonary TB

artículo científico publicado en 2016

TB control programmes remain an important gateway to HIV diagnosis in the era of expanded access to HIV care

artículo científico publicado en 2020

TST positivity in household contacts of tuberculosis patients: a case-contact study in Malawi.

artículo científico publicado en 2017

The ANC National Health Plan

artículo científico publicado en 1994

The impact of inclusion, dose and duration of pyrazinamide (PZA) on efficacy and safety outcomes in tuberculosis: systematic review and meta-analysis protocol

scientific article published on 17 December 2019

The implications of model-informed drug discovery and development for tuberculosis

artículo científico publicado en 2016

The increasing burden of tuberculosis in rural South Africa--impact of the HIV epidemic

artículo científico publicado el 1 de abril de 1997

Tuberculosis bacillary load, an early marker of disease severity: the utility of tuberculosis Molecular Bacterial Load Assay

artículo científico publicado en 2020

Twice-weekly, directly observed treatment for HIV-infected and uninfected tuberculosis patients: cohort study in rural South Africa

artículo científico publicado en 1999

Use of nonlinear mixed-effects analysis for improved precision of early pharmacodynamic measures in tuberculosis treatment

artículo científico publicado en 2006

Vitamin D deficiency in Malawian adults with pulmonary tuberculosis: risk factors and treatment outcomes

artículo científico publicado en 2015

Who fails to complete tuberculosis treatment? Temporal trends and risk factors for treatment interruption in a community-based directly observed therapy programme in a rural district of South Africa

artículo científico publicado en 1999

Lista de obras de

A Phase II study of the sterilising activities of ofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis

A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis

A rapid and sensitive HPLC–MS method for the detection of plasma and cellular rifampicin

Accelerating the transition of new tuberculosis drug combinations from Phase II to Phase III trials: New technologies and innovative designs

Adaptive clinical trials in tuberculosis: applications, challenges and solutions

Adequacy of Rifampin Absorption after Jejunostomy Tube Administration.

Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia (ARREST): study protocol for a randomised controlled trial

An integrated model of care for neurological infections: the first six years of referrals to a specialist service at a university teaching hospital in Northwest England

Assessment of the Efficacy of New Anti-Tuberculosis Drugs

Association of variants within the GST and other genes with anti-tubercular agents related toxicity: a systematic review and meta-analysis

Bedaquiline kills persistent Mycobacterium tuberculosis with no disease relapse: an in vivo model of a potential cure

Biomarkers for tuberculosis disease activity, cure, and relapse

Bridging the gap in the fight against tuberculosis

CYP genetic variants and toxicity related to anti-tubercular agents: a systematic review and meta-analysis

Comparing the efficacy of drug regimens for pulmonary tuberculosis: meta-analysis of endpoints in early phase clinical trials

Coping with Africa's increasing tuberculosis burden: are community supervisors an essential component of the DOT strategy? Directly observed therapy

Delivery of long-term-injectable agents for TB by lay carers: pragmatic randomised trial

Directly observed therapy for tuberculosis in rural South Africa, 1991 through 1994

Doubts about DOTS.

Early clinical development of anti-tuberculosis drugs: science, statistics and sterilizing activity

Effects of dosage, comorbidities, and food on isoniazid pharmacokinetics in Peruvian tuberculosis patients

Efficacy and Safety of High-Dose Rifampin in Pulmonary Tuberculosis. A Randomized Controlled Trial

Efficacy of twice weekly treatment for tuberculosis given under direct observation in Africa

Emergence of multidrug-resistant tuberculosis in a community-based directly observed treatment programme in rural South Africa.

Evaluation of high-dose rifampin in patients with new, smear-positive tuberculosis (HIRIF): study protocol for a randomized controlled trial

Evaluation of new antituberculosis drugs in mouse models

Fluoroquinolones for treating tuberculosis (presumed drug-sensitive)

Frequency of functional drug disposition gene polymorphism in Thai population: relevance to antiretroviral drugs

Genetic Determinants of the Pharmacokinetic Variability of Rifampin in Malawian Adults with Pulmonary Tuberculosis

HIV and tuberculosis

High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

Impact of the human immunodeficiency virus epidemic on mortality among adults with tuberculosis in rural South Africa, 1991-1995.

Importance of collection tube during clinical studies of oseltamivir

In routine UK hospital practice T-SPOT.TB™ is useful in some patients with a modest pre-test probability of active tuberculosis.

Influence of genetic variants on toxicity to anti-tubercular agents: a systematic review and meta-analysis (protocol)

Insufficient evidence for chest CT scan in TB outbreak investigation.

Intra-individual effects of food upon the pharmacokinetics of rifampicin and isoniazid

Intrapulmonary pharmacokinetics of first-line anti-TB drugs in Malawian tuberculosis patients

Investigation of Elimination Rate, Persistent Subpopulation Removal, and Relapse Rates of Mycobacterium tuberculosis by Using Combinations of First-Line Drugs in a Modified Cornell Mouse Model

Isoniazid activity is terminated by bacterial persistence

Kinetics of Mycobacterium tuberculosis-specific IFN-γ responses and sputum bacillary clearance in HIV-infected adults during treatment of pulmonary tuberculosis

Linezolid pharmacokinetics in MDR-TB: a systematic review, meta-analysis and Monte Carlo simulation.

Longitudinal Pharmacokinetic-Pharmacodynamic Biomarkers Correlate With Treatment Outcome in Drug-Sensitive Pulmonary Tuberculosis: A Population Pharmacokinetic-Pharmacodynamic Analysis

Making up the difference: ensuring the bioequivalence of fixed-dose combinations for tuberculosis

Methods for selecting regimen duration to prevent relapse in drug-susceptible and drug-resistant TB.

Mixture analysis of tuberculin survey data from northern Malawi and critique of the method.

Model-Based Relationship between the Molecular Bacterial Load Assay and Time to Positivity in Liquid Culture

Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in rural Africa

Mouse models of Japanese encephalitis virus infection: A systematic review and meta-analysis using a meta-regression approach

Moxifloxacin replacement in contemporary tuberculosis drug regimens is ineffective against persistent Mycobacterium tuberculosis: Novel insights from the Cornell mouse model.

Opinion: the pharmacometrics of infectious disease

Optimal doses of rifampicin in the standard drug regimen to shorten tuberculosis treatment duration and reduce relapse by eradicating persistent bacteria

Optimal sampling strategies for early pharmacodynamic measures in tuberculosis

Optimising molecular diagnostic capacity for effective control of tuberculosis in high-burden settings

Optimizing outpatient serial sputum colony counting for studies of tuberculosis treatment in resource-poor settings

Pediatric tuberculosis in rural South Africa--value of directly observed therapy

Perceptions of Research Bronchoscopy in Malawian Adults with Pulmonary Tuberculosis: A Cross-Sectional Study

Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis

Pharmacokinetics and pharmacodynamics in the development of anti-tuberculosis drugs

Pharmacokinetics of anti-TB drugs in Malawian children: reconsidering the role of ethambutol

Pharmacokinetics of co-formulated mefloquine and artesunate in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum infection in Burkina Faso

Pharmacokinetics of rifampin in Peruvian tuberculosis patients with and without comorbid diabetes or HIV

Pharmacologic considerations in use and development of antituberculosis drugs

Poor outcomes in recurrent tuberculosis: More than just drug resistance?

Population pharmacokinetic modelling of once-daily ritonavir-boosted darunavir in HIV-infected patients.

Population pharmacokinetics of ritonavir-boosted atazanavir in HIV-infected patients and healthy volunteers

Protocol for the development of the STrengthening the Reporting Of Pharmacogenetic Studies (STROPS) guideline: checklist of items for reporting pharmacogenetic studies

Publisher Correction: A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis

Rapid degradation of oseltamivir phosphate in clinical samples by plasma esterases

Re-growth of Mycobacterium tuberculosis populations exposed to antibiotic combinations is due to the presence of isoniazid and not bacterial growth rate

Recent advances in tuberculosis: New drugs and treatment regimens.

Reply to "adequate design of pharmacokinetic-pharmacodynamic studies will help optimize tuberculosis treatment for the future".

Reply to te Brake : Conflicting Findings on an Intermediate Dose of Rifampicin for Pulmonary Tuberculosis

Reported outcomes in phase II studies of newly-diagnosed pulmonary tuberculosis

Resistance to antituberculosis drugs in rural South Africa: rates, patterns, risks, and transmission dynamics

STrengthening the Reporting Of Pharmacogenetic Studies: Development of the STROPS guideline

Sales of over-the-counter remedies as an early warning system for winter bed crises ⬇️

Sequential population pharmacokinetic modeling of lopinavir and ritonavir in healthy volunteers and assessment of different dosing strategies

Serial image analysis of Mycobacterium tuberculosis colony growth reveals a persistent subpopulation in sputum during treatment of pulmonary TB