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A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog

Applying Microfluidics for the Production of the Cationic Liposome-Based Vaccine Adjuvant CAF09b

scientific article published on 19 December 2020

Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6,6'-dibehenate)-a novel adjuvant inducing both strong CMI and antibody responses

artículo científico publicado en 2005

Comparison of the Depot Effect and Immunogenicity of Liposomes Based on Dimethyldioctadecylammonium (DDA), 3β-[N-(N′,N′-Dimethylaminoethane)carbomyl] Cholesterol (DC-Chol), and 1,2-Dioleoyl-3-trimethylammonium Propane (DOTAP): Prolonged Liposome

High-throughput screening of excipients with a biological effect: a kinetic study on the effects of surfactants on efflux-mediated transport

artículo científico publicado en 2019

Investigating Prime-Pull Vaccination through a Combination of Parenteral Vaccination and Intranasal Boosting

artículo científico publicado en 2019

Investigating the Impact of Delivery System Design on the Efficacy of Self-Amplifying RNA Vaccines

scientific article published on 08 May 2020

Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce a CMI response

article

Liposomal vaccine delivery systems

scientific article published on 18 March 2011

Liposome-based cationic adjuvant formulations (CAF): past, present, and future

artículo científico publicado en 2009

Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen

artículo científico publicado en 2009

Manufacturing Considerations for the Development of Lipid Nanoparticles Using Microfluidics

scientific article published on 15 November 2020

Scalable solvent-free production of liposomes

scientific article published on 16 July 2020

Scale-Independent Microfluidic Production of Cationic Liposomal Adjuvants and Development of Enhanced Lymphatic Targeting Strategies

artículo científico publicado en 2019

Silk Nanoparticle Manufacture in Semi-Batch Format

artículo científico publicado en 2020

The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile

artículo científico publicado en 2016

alpha,alpha'-trehalose 6,6'-dibehenate in non-phospholipid-based liposomes enables direct interaction with trehalose, offering stability during freeze-drying

artículo científico publicado en 2008