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A 3-plex methylation assay combined with the FGFR3 mutation assay sensitively detects recurrent bladder cancer in voided urine

artículo científico publicado en 2013

A SNaPshot assay for the rapid and simple detection of four common hotspot codon mutations in the PIK3CA gene

artículo científico publicado en 2009

A Urine Based Genomic Assay to Triage Patients with Hematuria for Cystoscopy

artículo científico publicado en 2020

A methylation assay for the detection of non-muscle-invasive bladder cancer (NMIBC) recurrences in voided urine.

artículo científico publicado en 2011

A new system for substaging pT1 papillary bladder cancer: a prognostic evaluation

artículo científico publicado en 2005

A noninvasive multi-analyte diagnostic assay: combining protein and DNA markers to stratify bladder cancer patients

artículo científico publicado en 2012

A reported 20-gene expression signature to predict lymph node-positive disease at radical cystectomy for muscle-invasive bladder cancer is clinically not applicable.

artículo científico publicado en 2017

A simple and fast method for the simultaneous detection of nine fibroblast growth factor receptor 3 mutations in bladder cancer and voided urine

artículo científico publicado en 2005

Abstract 1932: Cationic amphiphilic drugs as a potential new treatment option for patients with high risk non-muscle invasive bladder cancer

scholarly article

Abstract 4023: Genome-wide analysis of CpG island methylation identified OTX1, OSR1 and ONECUT2 as biomarkers for recurrent bladder cancer detection in voided urine

Abstract 4897: Genome-wide analysis of CGIs in bladder cancer identifies novel epigenetic biomarkers for diagnosis and follow-up

article published in 2010

An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer

artículo científico publicado en 2021

Analysis of Point Mutations in Clinical Samples of Urothelial Carcinoma

artículo científico publicado en 2018

Bladder cancer biomarkers and their role in surveillance and screening

artículo científico publicado en 2009

Bladder cancer: novel molecular characteristics, diagnostic, and therapeutic implications

artículo científico publicado en 2010

Cationic amphiphilic drugs as potential anti-cancer therapy for bladder cancer

artículo científico publicado en 2020

Chromosomal instability in meningiomas

artículo científico publicado en 2005

Chromosome 9 deletions are more frequent than FGFR3 mutations in flat urothelial hyperplasias of the bladder.

artículo científico publicado en 2006

Clinical and Pathological Prognostic Factors for Recurrence, Progression and Mortality in Non-Muscle Invasive Bladder Cancer: A Meta-Analysis

Combinations of Urinary Biomarkers for Surveillance of Patients with Incident Nonmuscle Invasive Bladder Cancer: The European FP7 UROMOL Project

scientific article published on 28 November 2012

Combined microsatellite and FGFR3 mutation analysis enables a highly sensitive detection of urothelial cell carcinoma in voided urine

artículo científico publicado en 2003

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

artículo científico

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Comprehensive Transcriptional Analysis of Early-Stage Urothelial Carcinoma.

artículo científico publicado en 2016

Cystoscopy revisited as the gold standard for detecting bladder cancer recurrence: diagnostic review bias in the randomized, prospective CEFUB trial.

artículo científico publicado en 2010

DNA methylation-based biomarkers in bladder cancer

artículo científico

Defined morphological criteria allow reliable diagnosis of colorectal serrated polyps and predict polyp genetics

artículo científico publicado en 2014

Detection of multiple mutations in urinary exfoliated cells from male bladder cancer patients at diagnosis and during follow-up

artículo científico publicado en 2016

Detection of tumours of the urinary tract in voided urine

artículo científico publicado en 2008

Detection of urothelial bladder cancer cells in voided urine can be improved by a combination of cytology and standardized microsatellite analysis

artículo científico publicado en 2009

Development and Validation of Urine-based Peptide Biomarker Panels for Detecting Bladder Cancer in a Multi-center Study.

artículo científico publicado en 2016

Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines

artículo científico publicado en 2009

Divergent Biological Response to Neoadjuvant Chemotherapy in Muscle-invasive Bladder Cancer

scientific article published on 17 September 2018

Down-staging (<pT2) of urothelial cancer at cystectomy after the diagnosis of detrusor muscle invasion (pT2) at diagnostic transurethral resection (TUR): is prediction possible? ⬇️

artículo científico publicado el 10 de julio de 2012

Editorial Comment

Elevated Derived Neutrophil-to-Lymphocyte Ratio Corresponds With Poor Outcome in Patients Undergoing Pre-Operative Chemotherapy in Muscle-Invasive Bladder Cancer

artículo científico publicado en 2016

Epidermal nevus in association with some uncommon manifestations

artículo científico publicado en 2013

Evaluation of an Epigenetic Profile for the Detection of Bladder Cancer in Patients with Hematuria

artículo científico publicado en 2015

Expression of the endothelin axis in noninvasive and superficially invasive bladder cancer: relation to clinicopathologic and molecular prognostic parameters

artículo científico publicado en 2008

External validation of a multiplex urinary protein panel for the detection of bladder cancer in a multicenter cohort

artículo científico publicado en 2014

FGFR3 Mutation Analysis in Voided Urine Samples to Decrease Cystoscopies and Cost in Nonmuscle Invasive Bladder Cancer Surveillance: A Comparison of 3 Strategies

article

FGFR3 Mutation Status and FGFR3 Expression in a Large Bladder Cancer Cohort Treated by Radical Cystectomy: Implications for Anti-FGFR3 Treatment?†

artículo científico publicado en 2020

FGFR3 and P53 characterize alternative genetic pathways in the pathogenesis of urothelial cell carcinoma

artículo científico publicado en 2004

FGFR3 mutations and a normal CK20 staining pattern define low-grade noninvasive urothelial bladder tumours

artículo científico publicado en 2007

FGFR3 mutations in seborrheic keratoses are already present in flat lesions and associated with age and localization

scientific article published on 22 June 2007

FGFR3 mutations indicate better survival in invasive upper urinary tract and bladder tumours.

artículo científico publicado en 2008

FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy.

artículo científico publicado en 2010

FGFR3, TERT and OTX1 as a Urinary Biomarker Combination for Surveillance of Patients with Bladder Cancer in a Large Prospective Multicenter Study.

artículo científico publicado en 2016

Feasibility study of screening for bladder cancer with urinary molecular markers (the BLU-P project).

artículo científico publicado en 2010

Fibroblast growth factor receptor 3 mutation analysis on voided urine for surveillance of patients with low-grade non-muscle-invasive bladder cancer.

artículo científico publicado en 2010

Fibroblast growth factor receptor 3 mutations in bladder tumors correlate with low frequency of chromosome alterations

artículo científico publicado en 2008

FrequentFGFR3mutations in urothelial papilloma

article

Genome-wide analysis of CpG island methylation in bladder cancer identified TBX2, TBX3, GATA2, and ZIC4 as pTa-specific prognostic markers

artículo científico publicado en 2012

Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer

artículo científico publicado en 2014

HRAS mutations in bladder cancer at an early age and the possible association with the Costello Syndrome

artículo científico publicado en 2013

High frequency of FGFR3 mutations in adenoid seborrheic keratoses

artículo científico publicado en 2006

Hypermethylation of the polycomb group target gene PCDH7 in bladder tumors from patients of all ages

artículo científico publicado en 2013

Immunohistochemical and genetic profiles of endometrioid endometrial carcinoma arising from atrophic endometrium

artículo científico publicado en 2015

Immunohistochemical and molecular characterizations in urothelial carcinoma of bladder in patients less than 45 years

artículo científico publicado en 2017

Impact of Molecular Subtypes in Muscle-invasive Bladder Cancer on Predicting Response and Survival after Neoadjuvant Chemotherapy

artículo científico publicado en 2017

In-depth investigation of the molecular pathogenesis of bladder cancer in a unique 26-year old patient with extensive multifocal disease: a case report

artículo científico publicado en 2010

Intratumour heterogeneity in urologic cancers: from molecular evidence to clinical implications

artículo científico

KRAS and BRAF mutation analysis in routine molecular diagnostics: comparison of three testing methods on formalin-fixed, paraffin-embedded tumor-derived DNA.

artículo científico publicado en 2012

Keratinocytic epidermal nevi are associated with mosaic RAS mutations.

artículo científico publicado en 2012

Lack of genetic and epigenetic changes in meningiomas without NF2 loss

artículo científico publicado en 2006

Limited Funds for Bladder Cancer Research and What Can We Do About It.

artículo científico publicado en 2016

Liquid Biopsy Analysis of FGFR3 and PIK3CA Hotspot Mutations for Disease Surveillance in Bladder Cancer

artículo científico publicado en 2017

Long non-coding RNAs identify a subset of luminal muscle-invasive bladder cancer patients with favorable prognosis

artículo científico publicado en 2019

Low frequency of molecular changes and tumor recurrence in inverted papillomas of the urinary tract.

artículo científico publicado en 2007

MN1 affects expression of genes involved in hematopoiesis and can enhance as well as inhibit RAR/RXR-induced gene expression

artículo científico publicado en 2008

Markers predicting response to bacillus Calmette-Guérin immunotherapy in high-risk bladder cancer patients: a systematic review

artículo científico publicado en 2011

Meningioma 1 is required for appropriate osteoblast proliferation, motility, differentiation, and function

artículo científico publicado en 2009

Microhematuria assessment an IBCN consensus-Based upon a critical review of current guidelines

artículo científico publicado en 2016

Microsatellite analysis of voided-urine samples for surveillance of low-grade non-muscle-invasive urothelial carcinoma: feasibility and clinical utility in a prospective multicenter study (Cost-Effectiveness of Follow-Up of Urinary Bladder Cancer tr

artículo científico publicado en 2008

Molecular Grade (FGFR3/MIB-1) and EORTC Risk Scores Are Predictive in Primary Non–Muscle-Invasive Bladder Cancer

scientific article published on 09 June 2010

Molecular and clinical heterogeneity within the luminal subtype

scientific article published on 01 February 2020

Molecular and clinical support for a four-tiered grading system for bladder cancer based on the WHO 1973 and 2004 classifications

artículo científico publicado en 2014

Molecular changes during progression from nonmuscle invasive to advanced urothelial carcinoma

artículo científico publicado en 2019

Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MIB-1 is superior to pathologic grade for the prediction of clinical outcome

artículo científico publicado en 2003

Molecular markers increase precision of the European Association of Urology non-muscle invasive bladder cancer progression risk groups.

artículo científico publicado en 2018

Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi

artículo científico publicado en 2006

New horizons in bladder cancer research

artículo científico publicado en 2019

No evidence of FGFR3 mutations in prostate cancer ⬇️

artículo científico publicado el 18 de octubre de 2010

Non-muscle-invasive bladder cancer surveillance for which cystoscopy is partly replaced by microsatellite analysis of urine: a cost-effective alternative?

artículo científico publicado en 2008

Novel fibroblast growth factor receptor 3 (FGFR3) mutations in bladder cancer previously identified in non-lethal skeletal disorders

artículo científico publicado en 2002

Optimal Trial Design for Studying Urinary Markers in Bladder Cancer: A Collaborative Review

scientific article published on 15 May 2018

Optimization of Nonmuscle Invasive Bladder Cancer Recurrence Detection Using a Urine Based FGFR3 Mutation Assay ⬇️

artículo científico publicado el 17 de junio de 2011

Outcomes of a bladder cancer screening program using home hematuria testing and molecular markers.

artículo científico publicado en 2013

Patients' perceived burden of cystoscopic and urinary surveillance of bladder cancer: a randomized comparison

artículo científico publicado en 2007

Positive fibroblast growth factor receptor 3 immunoreactivity is associated with low-grade non-invasive urothelial bladder cancer

artículo científico publicado en 2015

Predicting Response to Intravesical Bacillus Calmette-Guérin Immunotherapy: Are We Moving Forward?

artículo científico publicado en 2015

Prediction of Multiple Recurrent Events: A Comparison of Extended Cox Models in Bladder Cancer

artículo científico

Prediction of Progression of Non–Muscle-Invasive Bladder Cancer by WHO 1973 and 2004 Grading and by FGFR3 Mutation Status: A Prospective Study

article

Prevalence and implications of TERT promoter mutation in uveal and conjunctival melanoma and in benign and premalignant conjunctival melanocytic lesions.

artículo científico publicado en 2014

Prognostic Impact of a 12-gene Progression Score in Non-muscle-invasive Bladder Cancer: A Prospective Multicentre Validation Study

artículo científico publicado en 2017

Prognostic value of molecular markers, sub-stage and European Organisation for the Research and Treatment of Cancer risk scores in primary T1 bladder cancer.

artículo científico publicado en 2012

Re: A urine-based genomic assay to triage patients with hematuria for cystoscopy

artículo científico publicado en 2020

Reply by Authors

artículo científico publicado en 2020

Risk prediction scores for recurrence and progression of non-muscle invasive bladder cancer: an international validation in primary tumours.

artículo científico publicado en 2014

Selection of microsatellite markers for bladder cancer diagnosis without the need for corresponding blood.

artículo científico publicado en 2012

Sexual function of patients under surveillance for bladder cancer

scientific article published on 14 January 2009

Spectrum of KIT/PDGFRA/BRAF mutations and Phosphatidylinositol-3-Kinase pathway gene alterations in gastrointestinal stromal tumors (GIST) ⬇️

artículo científico publicado el 6 de agosto de 2011

Stratification based on methylation of TBX2 and TBX3 into three molecular grades predicts progression in patients with pTa-bladder cancer

artículo científico publicado en 2014

Surveillance with microsatellite analysis of urine in bladder cancer patients treated by radiotherapy.

artículo científico publicado en 2003

Synchronous and metachronous urothelial carcinoma of the upper urinary tract and the bladder: Are they clonally related? A systematic review

artículo científico publicado en 2020

T1-Substaging of Non-muscle Invasive Bladder Cancer is Associated with BCG-Failure and Improves Patient Stratification at Diagnosis

artículo científico publicado en 2020

TERT promoter mutations and BRAF mutations are rare in sporadic, and TERT promoter mutations are absent in NF1-related malignant peripheral nerve sheath tumors

artículo científico publicado en 2014

Targeted disruption of the Mn1 oncogene results in severe defects in development of membranous bones of the cranial skeleton.

artículo científico publicado en 2005

Targeted therapies in bladder cancer: an overview of in vivo research

artículo científico

Telomerase reverse transcriptase promoter mutations in bladder cancer: high frequency across stages, detection in urine, and lack of association with outcome

artículo científico publicado en 2013

Telomerase reverse transcriptase promoter mutations in tumors originating from the adrenal gland and extra-adrenal paraganglia

artículo científico publicado en 2014

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The ETS family member TEL binds to nuclear receptors RAR and RXR and represses gene activation.

artículo científico publicado en 2011

The FGFR3 mutation is related to favorable pT1 bladder cancer.

artículo científico publicado en 2011

The MN1 oncoprotein activates transcription of the IGFBP5 promoter through a CACCC-rich consensus sequence

artículo científico publicado en 2007

The MN1 oncoprotein synergizes with coactivators RAC3 and p300 in RAR-RXR-mediated transcription.

artículo científico publicado en 2003

The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice.

artículo científico publicado en 2008

The RAS-BRAF kinase pathway is not involved in uveal melanoma

artículo científico publicado en 2004

The absence of BRAF, FGFR3, and PIK3CA mutations differentiates lentigo simplex from melanocytic nevus and solar lentigo

artículo científico publicado en 2009

The clonal relation of primary upper urinary tract urothelial carcinoma and paired urothelial carcinoma of the bladder

scientific article published on 02 October 2020

The development of multiple bladder tumour recurrences in relation to the FGFR3 mutation status of the primary tumour.

artículo científico publicado en 2009

The diagnostic accuracy of methylation markers in urine for the detection of bladder cancer: a systematic review

artículo científico publicado en 2018

The leukemia-associated fusion protein MN1-TEL blocks TEL-specific recognition sequences.

artículo científico publicado en 2012

The random development of LOH on chromosome 9q in superficial bladder cancers

artículo científico publicado en 2002

The use of molecular analyses in voided urine for the assessment of patients with hematuria.

artículo científico publicado en 2013

Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes

artículo científico publicado en 2010

Urinary peptide panel for prognostic assessment of bladder cancer relapse

artículo científico publicado en 2019

Validation of a DNA Methylation-Mutation Urine Assay to Select Patients with Hematuria for Cystoscopy

artículo científico publicado en 2016

[Correlation of FGFR3 mutations and chromosomal alterations in bladder cancer]

artículo científico publicado en 2006

[Urothelial neoplasms in individuals younger than 20 years show very few genetic alterations and have a favourable clinical outcome]

artículo científico publicado en 2006

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