Lista de obras -

A Formulated TLR7/8 Agonist is a Flexible, Highly Potent and Effective Adjuvant for Pandemic Influenza Vaccines

artículo científico publicado en 2017

A Nanostructured Lipid Carrier for Delivery of a Replicating Viral RNA Provides Single, Low-Dose Protection against Zika

scholarly article by Jesse H Erasmus et al published 2 August 2018 in Molecular Therapy

A Novel Synthetic TLR-4 Agonist Adjuvant Increases the Protective Response to a Clinical-Stage West Nile Virus Vaccine Antigen in Multiple Formulations

artículo científico publicado en 2016

A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine for use in the prevention of visceral leishmaniasis

article by Jaya Chakravarty et al published April 2011 in Vaccine

A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine when used in combination with meglumine antimoniate for the treatment of cutaneous leishmaniasis

artículo científico publicado en 2010

A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine when used in combination with sodium stibogluconate for the treatment of mucosal leishmaniasis

artículo científico publicado en 2010

A combination of TLR-4 agonist and saponin adjuvants increases antibody diversity and protective efficacy of a recombinant West Nile Virus antigen

article published in 2018

A defined subunit vaccine that protects against vector-borne visceral leishmaniasis

artículo científico publicado en 2017

A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosis

artículo científico publicado en 2010

A dual TLR agonist adjuvant enhances the immunogenicity and protective efficacy of the tuberculosis vaccine antigen ID93.

scientific article published on 03 January 2014

A phase 1 antigen dose escalation trial to evaluate safety, tolerability and immunogenicity of the leprosy vaccine candidate LepVax (LEP-F1 + GLA-SE) in healthy adults

scientific article published on 30 December 2019

A structure-function approach to optimizing TLR4 ligands for human vaccines

artículo científico publicado en 2016

A synthetic adjuvant to enhance and expand immune responses to influenza vaccines

artículo científico publicado en 2010

Adjuvant formulation structure and composition are critical for the development of an effective vaccine against tuberculosis

artículo científico publicado en 2013

Adjuvanted pandemic influenza vaccine: variation of emulsion components affects stability, antigen structure, and vaccine efficacy

artículo científico publicado en 2012

Advancing Translational Science for Pulmonary NTM Infections: A Roadmap for Research

artículo científico publicado en 2019

An mRNA Vaccine against SARS-CoV-2 - Preliminary Report

artículo científico publicado en 2020

Antigen presentation by B cells guides programing of memory CD4+ T-cell responses to a TLR4-agonist containing vaccine in mice

artículo científico publicado en 2016

Bioinformatic identification of tandem repeat antigens of the Leishmania donovani complex

artículo científico publicado en 2006

Broadened immunity and protective responses with emulsion-adjuvanted H5 COBRA-VLP vaccines

artículo científico publicado en 2017

CD11a and CD49d enhance the detection of antigen-specific T cells following human vaccination

artículo científico publicado en 2017

Chitin microneedles for an easy-to-use tuberculosis skin test

artículo científico publicado en 2013

Cloning, characterization, and serodiagnostic evaluation of Leishmania infantum tandem repeat proteins

artículo científico publicado en 2006

Comparative Systems Analyses Reveal Molecular Signatures of Clinically tested Vaccine Adjuvants

artículo científico publicado en 2016

Cryogenic transmission electron microscopy of recombinant tuberculosis vaccine antigen with anionic liposomes reveals formation of flattened liposomes

artículo científico publicado en 2014

Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys

scholarly article

Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant

artículo científico publicado en 2011

Development of a leishmaniasis vaccine: the importance of MPL.

artículo científico publicado en 2003

Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens

artículo científico publicado en 2016

Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ)

artículo científico publicado en 2012

E114 Rational Design and Clinical Development of New Adjuvants

article

Effect of chemotherapy on whole-blood cytokine responses to Mycobacterium tuberculosis antigens in a small cohort of patients with pulmonary tuberculosis

artículo científico publicado en 2011

Elimination of the cold-chain dependence of a nanoemulsion adjuvanted vaccine against tuberculosis by lyophilization

scientific article published on 29 December 2013

Enhanced Anti-Mycobacterium tuberculosis Immunity over Time with Combined Drug and Immunotherapy Treatment.

artículo científico publicado en 2018

Enhanced humoral and Type 1 cellular immune responses with Fluzone adjuvanted with a synthetic TLR4 agonist formulated in an emulsion

artículo científico publicado en 2009

Evaluation of diagnostic performance of rK28 ELISA using urine for diagnosis of visceral leishmaniasis

artículo científico publicado en 2016

From mouse to man: safety, immunogenicity and efficacy of a candidate leishmaniasis vaccine LEISH-F3+GLA-SE.

artículo científico publicado en 2015

Glucopyranosyl Lipid Adjuvant (GLA), a Synthetic TLR4 agonist, promotes potent systemic and mucosal responses to intranasal immunization with HIVgp140.

artículo científico publicado en 2012

Identification and characterization of novel recombinant vaccine antigens for immunization against genital Chlamydia trachomatis

artículo científico publicado en 2009

Identification of Mycobacterium tuberculosis vaccine candidates using human CD4+ T-cells expression cloning

artículo científico publicado en 2008

Identification of human T cell antigens for the development of vaccines against Mycobacterium tuberculosis

artículo científico publicado en 2008

Immune subdominant antigens as vaccine candidates against Mycobacterium tuberculosis

artículo científico publicado en 2014

Immunisation with ID83 fusion protein induces antigen-specific cell mediated and humoral immune responses in cattle

artículo científico publicado en 2013

Immunization with a polyprotein vaccine consisting of the T-Cell antigens thiol-specific antioxidant, Leishmania major stress-inducible protein 1, and Leishmania elongation initiation factor protects against leishmaniasis

artículo científico publicado en 2002

Immunologic correlates of protection and potential role for adjuvants to improve influenza vaccines in older adults ⬇️

artículo científico publicado el 1 de julio de 2013

Immunotherapy for drug-refractory mucosal leishmaniasis

artículo científico publicado en 2006

Improved Immune Responses in Young and Aged Mice with Adjuvanted Vaccines against H1N1 Influenza Infection

artículo científico publicado en 2018

Increased potency of an inactivated trivalent polio vaccine with oil-in-water emulsions

artículo científico publicado en 2010

Interferon γ and Tumor Necrosis Factor Are Not Essential Parameters of CD4+ T-Cell Responses for Vaccine Control of Tuberculosis

artículo científico publicado en 2015

Intradermal immunization improves protective efficacy of a novel TB vaccine candidate

scientific article published on 26 March 2009

Intramuscular Delivery of Replicon RNA Encoding ZIKV-117 Human Monoclonal Antibody Protects against Zika Virus Infection

artículo científico publicado en 2020

Leish-111f, a recombinant polyprotein vaccine that protects against visceral Leishmaniasis by elicitation of CD4+ T cells

artículo científico publicado en 2007

Leishmania infantum sterol 24-c-methyltransferase formulated with MPL-SE induces cross-protection against L. major infection

artículo científico publicado en 2009

Long-term protective efficacy with a BCG-prime ID93/GLA-SE boost regimen against the hyper-virulent Mycobacterium tuberculosis strain K in a mouse model

scientific article published on 29 October 2019

Memory CD4+ T cells enhance B-cell responses to drifting influenza immunization

scientific article published on 21 December 2018

Mucosal delivery switches the response to an adjuvanted tuberculosis vaccine from systemic TH1 to tissue-resident TH17 responses without impacting the protective efficacy

artículo científico publicado en 2015

MyD88 and TRIF synergistic interaction is required for TH1-cell polarization with a synthetic TLR4 agonist adjuvant

scientific article published on 03 July 2013

Mycobacterium tuberculosis Rv0198c, a putative matrix metalloprotease is involved in pathogenicity ⬇️

artículo científico publicado el 8 de enero de 2011

New horizons in adjuvants for vaccine development

scientific article published on 06 December 2008

Optimized subunit vaccine protects against experimental leishmaniasis

scientific article published on 26 September 2009

Optimizing Immunization Strategies for the Induction of Antigen-Specific CD4 and CD8 T Cell Responses for Protection against Intracellular Parasites.

scientific article published on 27 July 2016

Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization

scientific article published on 01 December 2019

Overcoming the Neonatal Limitations of Inducing Germinal Centers through Liposome-Based Adjuvants Including C-Type Lectin Agonists Trehalose Dibehenate or Curdlan

artículo científico publicado en 2018

Physicochemical characterization and biological activity of synthetic TLR4 agonist formulations

artículo científico publicado en 2009

Pre-clinical antigenicity studies of an innovative multivalent vaccine for human visceral leishmaniasis

artículo científico publicado en 2017

Prophylaxis of Mycobacterium tuberculosis H37Rv Infection in a Preclinical Mouse Model via Inhalation of Nebulized Bacteriophage D29

artículo científico publicado en 2019

Protection against Mycobacterium leprae infection by the ID83/GLA-SE and ID93/GLA-SE vaccines developed for tuberculosis

artículo científico publicado en 2014

Protection against tuberculosis with homologous or heterologous protein/vector vaccine approaches is not dependent on CD8+ T cells

scientific article published on 31 July 2013

Protection and Long-Lived Immunity Induced by the ID93/GLA-SE Vaccine Candidate against a Clinical Mycobacterium tuberculosis Isolate

artículo científico publicado en 2015

Protection of mice from Mycobacterium tuberculosis by ID87/GLA-SE, a novel tuberculosis subunit vaccine candidate.

artículo científico publicado en 2011

Protective efficacy of a tandemly linked, multi-subunit recombinant leishmanial vaccine (Leish-111f) formulated in MPL adjuvant

artículo científico publicado en 2002

Protective immunization against visceral leishmaniasis using Leishmania sterol 24-c-methyltransferase formulated in adjuvant

artículo científico publicado en 2007

Pulmonary immunity and durable protection induced by the ID93/GLA-SE vaccine candidate against the hyper-virulent Korean Beijing Mycobacterium tuberculosis strain K.

artículo científico publicado en 2016

Recombinant polymorphic membrane protein D in combination with a novel, second-generation lipid adjuvant protects against intra-vaginal Chlamydia trachomatis infection in mice

artículo científico publicado en 2016

Safety and immunogenicity of a defined vaccine for the prevention of cutaneous leishmaniasis

artículo científico publicado en 2009

Safety and immunogenicity of the novel tuberculosis vaccine ID93 + GLA-SE in BCG-vaccinated healthy adults in South Africa: a randomised, double-blind, placebo-controlled phase 1 trial

artículo científico publicado en 2018

Schistosomiasis vaccine candidate Sm14/GLA-SE: Phase 1 safety and immunogenicity clinical trial in healthy, male adults.

artículo científico publicado en 2015

Second-generation vaccines against leishmaniasis

artículo científico publicado en 2005

Strategic evaluation of vaccine candidate antigens for the prevention of Visceral Leishmaniasis

artículo científico publicado en 2016

TLR4 ligand formulation causes distinct effects on antigen-specific cell-mediated and humoral immune responses

artículo científico publicado en 2013

Taking toll: lipid A mimetics as adjuvants and immunomodulators

artículo científico publicado en 2002

The ID93 tuberculosis vaccine candidate does not induce sensitivity to purified protein derivative

artículo científico publicado en 2014

The TLR-4 agonist adjuvant, GLA-SE, improves magnitude and quality of immune responses elicited by the ID93 tuberculosis vaccine: first-in-human trial

article

The TLR4 Agonist Vaccine Adjuvant, GLA-SE, Requires Canonical and Atypical Mechanisms of Action for TH1 Induction

artículo científico publicado en 2016

The complexities and challenges of preventing and treating nontuberculous mycobacterial diseases

scientific article published on 14 February 2019

The importance of adjuvant formulation in the development of a tuberculosis vaccine

artículo científico publicado en 2012

The stimulatory effect of the TLR4-mediated adjuvant glucopyranosyl lipid A is well preserved in old age.

artículo científico publicado en 2015

Therapeutic immunization against Mycobacterium tuberculosis is an effective adjunct to antibiotic treatment

artículo científico publicado en 2012

Therapeutic vaccination against relevant high virulence clinical isolates of Mycobacterium tuberculosis

artículo científico publicado en 2013

Transcriptional profiling of TLR-4/7/8-stimulated guinea pig splenocytes and whole blood by bDNA assay ⬇️

artículo científico publicado el 3 de agosto de 2011

Vaccination Produces CD4 T Cells with a Novel CD154-CD40-Dependent Cytolytic Mechanism

artículo científico publicado en 2015

Vaccination of aged mice with adjuvanted recombinant influenza nucleoprotein enhances protective immunity

artículo científico publicado en 2020

Vaccination with heat-killed leishmania antigen or recombinant leishmanial protein and CpG oligodeoxynucleotides induces long-term memory CD4+ and CD8+ T cell responses and protection against leishmania major infection

artículo científico publicado en 2002

Lista de obras de

A Formulated TLR7/8 Agonist is a Flexible, Highly Potent and Effective Adjuvant for Pandemic Influenza Vaccines

A Nanostructured Lipid Carrier for Delivery of a Replicating Viral RNA Provides Single, Low-Dose Protection against Zika

A Novel Synthetic TLR-4 Agonist Adjuvant Increases the Protective Response to a Clinical-Stage West Nile Virus Vaccine Antigen in Multiple Formulations

A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine for use in the prevention of visceral leishmaniasis

A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine when used in combination with meglumine antimoniate for the treatment of cutaneous leishmaniasis

A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine when used in combination with sodium stibogluconate for the treatment of mucosal leishmaniasis

A combination of TLR-4 agonist and saponin adjuvants increases antibody diversity and protective efficacy of a recombinant West Nile Virus antigen

A defined subunit vaccine that protects against vector-borne visceral leishmaniasis

A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosis

A dual TLR agonist adjuvant enhances the immunogenicity and protective efficacy of the tuberculosis vaccine antigen ID93.

A phase 1 antigen dose escalation trial to evaluate safety, tolerability and immunogenicity of the leprosy vaccine candidate LepVax (LEP-F1 + GLA-SE) in healthy adults

A structure-function approach to optimizing TLR4 ligands for human vaccines

A synthetic adjuvant to enhance and expand immune responses to influenza vaccines

Adjuvant formulation structure and composition are critical for the development of an effective vaccine against tuberculosis

Adjuvanted pandemic influenza vaccine: variation of emulsion components affects stability, antigen structure, and vaccine efficacy

Advancing Translational Science for Pulmonary NTM Infections: A Roadmap for Research

An mRNA Vaccine against SARS-CoV-2 - Preliminary Report

Antigen presentation by B cells guides programing of memory CD4+ T-cell responses to a TLR4-agonist containing vaccine in mice

Bioinformatic identification of tandem repeat antigens of the Leishmania donovani complex

Broadened immunity and protective responses with emulsion-adjuvanted H5 COBRA-VLP vaccines

CD11a and CD49d enhance the detection of antigen-specific T cells following human vaccination

Chitin microneedles for an easy-to-use tuberculosis skin test

Cloning, characterization, and serodiagnostic evaluation of Leishmania infantum tandem repeat proteins

Comparative Systems Analyses Reveal Molecular Signatures of Clinically tested Vaccine Adjuvants

Cryogenic transmission electron microscopy of recombinant tuberculosis vaccine antigen with anionic liposomes reveals formation of flattened liposomes

Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys

Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant

Development of a leishmaniasis vaccine: the importance of MPL.

Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens

Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ)

E114 Rational Design and Clinical Development of New Adjuvants

Effect of chemotherapy on whole-blood cytokine responses to Mycobacterium tuberculosis antigens in a small cohort of patients with pulmonary tuberculosis

Elimination of the cold-chain dependence of a nanoemulsion adjuvanted vaccine against tuberculosis by lyophilization

Enhanced Anti-Mycobacterium tuberculosis Immunity over Time with Combined Drug and Immunotherapy Treatment.

Enhanced humoral and Type 1 cellular immune responses with Fluzone adjuvanted with a synthetic TLR4 agonist formulated in an emulsion

Evaluation of diagnostic performance of rK28 ELISA using urine for diagnosis of visceral leishmaniasis

From mouse to man: safety, immunogenicity and efficacy of a candidate leishmaniasis vaccine LEISH-F3+GLA-SE.

Glucopyranosyl Lipid Adjuvant (GLA), a Synthetic TLR4 agonist, promotes potent systemic and mucosal responses to intranasal immunization with HIVgp140.

Identification and characterization of novel recombinant vaccine antigens for immunization against genital Chlamydia trachomatis

Identification of Mycobacterium tuberculosis vaccine candidates using human CD4+ T-cells expression cloning

Identification of human T cell antigens for the development of vaccines against Mycobacterium tuberculosis

Immune subdominant antigens as vaccine candidates against Mycobacterium tuberculosis

Immunisation with ID83 fusion protein induces antigen-specific cell mediated and humoral immune responses in cattle

Immunization with a polyprotein vaccine consisting of the T-Cell antigens thiol-specific antioxidant, Leishmania major stress-inducible protein 1, and Leishmania elongation initiation factor protects against leishmaniasis

Immunologic correlates of protection and potential role for adjuvants to improve influenza vaccines in older adults ⬇️

Immunotherapy for drug-refractory mucosal leishmaniasis

Improved Immune Responses in Young and Aged Mice with Adjuvanted Vaccines against H1N1 Influenza Infection

Increased potency of an inactivated trivalent polio vaccine with oil-in-water emulsions

Interferon γ and Tumor Necrosis Factor Are Not Essential Parameters of CD4+ T-Cell Responses for Vaccine Control of Tuberculosis

Intradermal immunization improves protective efficacy of a novel TB vaccine candidate

Intramuscular Delivery of Replicon RNA Encoding ZIKV-117 Human Monoclonal Antibody Protects against Zika Virus Infection

Leish-111f, a recombinant polyprotein vaccine that protects against visceral Leishmaniasis by elicitation of CD4+ T cells

Leishmania infantum sterol 24-c-methyltransferase formulated with MPL-SE induces cross-protection against L. major infection

Long-term protective efficacy with a BCG-prime ID93/GLA-SE boost regimen against the hyper-virulent Mycobacterium tuberculosis strain K in a mouse model

Memory CD4+ T cells enhance B-cell responses to drifting influenza immunization

Mucosal delivery switches the response to an adjuvanted tuberculosis vaccine from systemic TH1 to tissue-resident TH17 responses without impacting the protective efficacy

MyD88 and TRIF synergistic interaction is required for TH1-cell polarization with a synthetic TLR4 agonist adjuvant

Mycobacterium tuberculosis Rv0198c, a putative matrix metalloprotease is involved in pathogenicity ⬇️

New horizons in adjuvants for vaccine development

Optimized subunit vaccine protects against experimental leishmaniasis

Optimizing Immunization Strategies for the Induction of Antigen-Specific CD4 and CD8 T Cell Responses for Protection against Intracellular Parasites.

Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization

Overcoming the Neonatal Limitations of Inducing Germinal Centers through Liposome-Based Adjuvants Including C-Type Lectin Agonists Trehalose Dibehenate or Curdlan

Physicochemical characterization and biological activity of synthetic TLR4 agonist formulations

Pre-clinical antigenicity studies of an innovative multivalent vaccine for human visceral leishmaniasis

Prophylaxis of Mycobacterium tuberculosis H37Rv Infection in a Preclinical Mouse Model via Inhalation of Nebulized Bacteriophage D29

Protection against Mycobacterium leprae infection by the ID83/GLA-SE and ID93/GLA-SE vaccines developed for tuberculosis

Protection against tuberculosis with homologous or heterologous protein/vector vaccine approaches is not dependent on CD8+ T cells

Protection and Long-Lived Immunity Induced by the ID93/GLA-SE Vaccine Candidate against a Clinical Mycobacterium tuberculosis Isolate

Protection of mice from Mycobacterium tuberculosis by ID87/GLA-SE, a novel tuberculosis subunit vaccine candidate.

Protective efficacy of a tandemly linked, multi-subunit recombinant leishmanial vaccine (Leish-111f) formulated in MPL adjuvant

Protective immunization against visceral leishmaniasis using Leishmania sterol 24-c-methyltransferase formulated in adjuvant

Pulmonary immunity and durable protection induced by the ID93/GLA-SE vaccine candidate against the hyper-virulent Korean Beijing Mycobacterium tuberculosis strain K.

Recombinant polymorphic membrane protein D in combination with a novel, second-generation lipid adjuvant protects against intra-vaginal Chlamydia trachomatis infection in mice

Safety and immunogenicity of a defined vaccine for the prevention of cutaneous leishmaniasis

Safety and immunogenicity of the novel tuberculosis vaccine ID93 + GLA-SE in BCG-vaccinated healthy adults in South Africa: a randomised, double-blind, placebo-controlled phase 1 trial

Schistosomiasis vaccine candidate Sm14/GLA-SE: Phase 1 safety and immunogenicity clinical trial in healthy, male adults.

Second-generation vaccines against leishmaniasis

Strategic evaluation of vaccine candidate antigens for the prevention of Visceral Leishmaniasis