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A domain level interaction network of amyloid precursor protein and Abeta of Alzheimer's disease

artículo científico

A harmonized longitudinal biomarkers and cognition database for assessing the natural history of preclinical Alzheimer's disease from young adulthood and for designing prevention trials

artículo científico publicado en 2019

ATN profiles among cognitively normal individuals and longitudinal cognitive outcomes

scientific article published on 06 March 2019

Behavioural phenotype of APPC100.V717F transgenic mice over-expressing a mutant Abeta-bearing fragment is associated with reduced NMDA receptor density

artículo científico publicado en 2010

Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease

artículo científico publicado en 2013

Chronic exposure to high levels of zinc or copper has little effect on brain metal homeostasis or Abeta accumulation in transgenic APP-C100 mice

artículo científico publicado en 2009

Copper promotes the trafficking of the amyloid precursor protein

artículo científico publicado en 2010

Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity

artículo científico publicado en 2006

Enduring Elevations of Hippocampal Amyloid Precursor Protein and Iron Are Features of β-Amyloid Toxicity and Are Mediated by Tau

artículo científico publicado en 2015

Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: implications for Alzheimer beta-amyloid pathology

artículo científico publicado en 2006

Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation

scholarly article

Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults.

artículo científico

Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

artículo científico publicado en 2003

Metals and amyloid-beta in Alzheimer's disease

artículo científico publicado en 2005

Mitochondrial oxidative stress causes hyperphosphorylation of tau.

artículo científico publicado en 2007

Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis.

artículo científico publicado en 2014

Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron

artículo científico publicado en 2002

Paradoxical condensation of copper with elevated beta-amyloid in lipid rafts under cellular copper deficiency conditions: implications for Alzheimer disease

artículo científico publicado en 2009

Plasma amyloid beta42 and amyloid beta40 levels are associated with early cognitive dysfunction after cardiac surgery

artículo científico publicado en 2009

Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

artículo científico publicado en 2008

Selenium Levels in Serum, Red Blood Cells, and Cerebrospinal Fluid of Alzheimer's Disease Patients: A Report from the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL).

artículo científico publicado en 2017

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

artículo científico publicado en 2011

The Transcription Factor MYB59 Regulates K/NO Translocation in the Arabidopsis Response to Low K Stress

scientific article published on 13 February 2019

Traumatic brain injury induces elevation of Co in the human brain

artículo científico publicado en 2014

Utility of an Alzheimer's Disease Risk-Weighted Polygenic Risk Score for Predicting Rates of Cognitive Decline in Preclinical Alzheimer's Disease: A Prospective Longitudinal Study

artículo científico publicado en 2018

β-amyloid in biological samples: not all Aβ detection methods are created equal

artículo científico publicado en 2014