Lista de obras -

A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis

artículo científico publicado en 2009

A novel DDB2 mutation causes defective recognition of UV-induced DNA damages and prevalent equine squamous cell carcinoma

scientific article published on 12 November 2020

A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate.

artículo científico publicado en 2015

Aging, graying and loss of melanocyte stem cells.

artículo científico publicado en 2007

An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1

artículo científico publicado en 2018

Approaching TERRA Firma: Genomic Functions of Telomeric Noncoding RNA.

artículo científico publicado en 2017

Complex roles for telomeres and telomerase in breast carcinogenesis

artículo científico publicado en 2003

Conditional telomerase induction causes proliferation of hair follicle stem cells ⬇️

artículo científico publicado en 2005

Constitutive telomerase expression promotes mammary carcinomas in aging mice

artículo científico publicado en 2002

Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres

artículo científico publicado en 2017

DNA repair: Telomere-lengthening mechanism revealed.

artículo científico publicado en 2016

DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse

scientific journal article

Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease

artículo científico publicado en 2019

Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita

artículo científico publicado en 2011

Distributed hepatocytes expressing telomerase repopulate the liver in homeostasis and injury

artículo científico publicado en 2018

Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells.

artículo científico publicado en 2016

Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions

artículo científico publicado en 2011

HiChIRP reveals RNA-associated chromosome conformation

artículo científico publicado en 2019

High telomerase is a hallmark of undifferentiated spermatogonia and is required for maintenance of male germline stem cells

artículo científico publicado en 2015

Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly

artículo científico publicado en 2008

In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases ⬇️

artículo científico publicado el 1 de noviembre de 2011

Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis

artículo científico publicado en 2014

Keeping It in the Family: ATRX Loss Promotes Persistent Sister Telomere Cohesion in ALT Cancer Cells

artículo científico publicado en 2015

Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation

artículo científico publicado en 2020

Pathways connecting telomeres and p53 in senescence, apoptosis, and cancer

artículo científico publicado en 2005

Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1

artículo científico publicado en 2014

Pulmonary arteriovenous malformations: an uncharacterised phenotype of dyskeratosis congenita and related telomere biology disorders.

artículo científico publicado en 2016

Purification of GFRα1+ and GFRα1- Spermatogonial Stem Cells Reveals a Niche-Dependent Mechanism for Fate Determination

artículo científico publicado en 2018

Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain

scientific journal article

Regulation of human telomerase in homeostasis and disease

artículo científico publicado en 2020

Reverse transcribing the code for chromosome stability

artículo científico publicado en 2009

Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice

artículo científico publicado en 2015

Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling

artículo científico publicado en 2011

Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.

artículo científico publicado en 2010

Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice

artículo científico publicado en 2010

Stem Cells and Aging: What's Next?

artículo científico publicado en 2015

Stem cell aging and aberrant differentiation within the niche

scientific article published on 01 July 2009

TCAB1: driving telomerase to Cajal bodies

artículo científico publicado en 2009

TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program

artículo científico publicado en 2007

TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends

artículo científico publicado en 2012

TRAPping telomerase within the intestinal stem cell niche ⬇️

artículo científico publicado el 16 de marzo de 2011

Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus

Telomerase flies the coop: the telomerase RNA component as a viral-encoded oncogene

artículo científico publicado en 2006

Telomerase modulates Wnt signalling by association with target gene chromatin

artículo científico publicado en 2009

Telomerase-dependent and -independent chromosome healing in mouse embryonic stem cells

artículo científico publicado en 2008

Telomere dysfunction provokes regional amplification and deletion in cancer genomes

artículo científico publicado en 2002

Telomere protection and TRF2 expression are enhanced by the canonical Wnt signalling pathway.

artículo científico publicado en 2013

Telomere shortening and cell fates in mouse models of neoplasia

artículo científico publicado en 2002

Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells

artículo científico publicado en 2011

Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo

artículo científico publicado en 2007

Telomere uncapping, chromosomes, and carcinomas

artículo científico publicado en 2009

Telomeres and telomerase in cancer

artículo científico publicado en 2009

Telomeres, telomerase, and human disease

artículo científico publicado en 2006

The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans

artículo científico publicado en 2022

Understanding telomere diseases through analysis of patient-derived iPS cells ⬇️

artículo científico publicado el 28 de agosto de 2013

Lista de obras de

A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis

A novel DDB2 mutation causes defective recognition of UV-induced DNA damages and prevalent equine squamous cell carcinoma

A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate.

Aging, graying and loss of melanocyte stem cells.

An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1

Approaching TERRA Firma: Genomic Functions of Telomeric Noncoding RNA.

Complex roles for telomeres and telomerase in breast carcinogenesis

Conditional telomerase induction causes proliferation of hair follicle stem cells ⬇️

Constitutive telomerase expression promotes mammary carcinomas in aging mice

Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres

DNA repair: Telomere-lengthening mechanism revealed.

DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse

Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease

Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita

Distributed hepatocytes expressing telomerase repopulate the liver in homeostasis and injury

Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells.

Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions

HiChIRP reveals RNA-associated chromosome conformation

High telomerase is a hallmark of undifferentiated spermatogonia and is required for maintenance of male germline stem cells

Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly

In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases ⬇️

Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis

Keeping It in the Family: ATRX Loss Promotes Persistent Sister Telomere Cohesion in ALT Cancer Cells

Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation

Pathways connecting telomeres and p53 in senescence, apoptosis, and cancer

Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1

Pulmonary arteriovenous malformations: an uncharacterised phenotype of dyskeratosis congenita and related telomere biology disorders.

Purification of GFRα1+ and GFRα1- Spermatogonial Stem Cells Reveals a Niche-Dependent Mechanism for Fate Determination

Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain

Regulation of human telomerase in homeostasis and disease

Reverse transcribing the code for chromosome stability

Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice

Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling

Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.

Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice

Stem Cells and Aging: What's Next?

Stem cell aging and aberrant differentiation within the niche

TCAB1: driving telomerase to Cajal bodies

TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program

TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends

TRAPping telomerase within the intestinal stem cell niche ⬇️

Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus

Telomerase flies the coop: the telomerase RNA component as a viral-encoded oncogene

Telomerase modulates Wnt signalling by association with target gene chromatin

Telomerase-dependent and -independent chromosome healing in mouse embryonic stem cells

Telomere dysfunction provokes regional amplification and deletion in cancer genomes

Telomere protection and TRF2 expression are enhanced by the canonical Wnt signalling pathway.

Telomere shortening and cell fates in mouse models of neoplasia

Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells

Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo

Telomere uncapping, chromosomes, and carcinomas

Telomeres and telomerase in cancer

Telomeres, telomerase, and human disease

The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans

Understanding telomere diseases through analysis of patient-derived iPS cells ⬇️