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A Proof of Concept of the Usefulness of a TDM-Guided Strategy for Optimizing Pharmacokinetic/Pharmacodynamic Target of Continuous Infusion Ampicillin-Based Regimens in a Case Series of Patients with Enterococcal Bloodstream Infections and/or Endocar

artículo científico publicado en 2022

Activation of an early feedback survival loop involving phospho-ErbB3 is a general response of melanoma cells to RAF/MEK inhibition and is abrogated by anti-ErbB3 antibodies.

artículo científico publicado en 2013

Activation of the ErbB3-AKT axis promotes melanoma cell survival and proliferation in response to RAF/MEK inhibition.

artículo científico publicado en 2014

Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells.

artículo científico

Combination of antibodies directed against different ErbB3 surface epitopes prevents the establishment of resistance to BRAF/MEK inhibitors in melanoma.

artículo científico publicado en 2015

Comparative serum bactericidal activity of meropenem-based combination regimens against extended-spectrum beta-lactamase and KPC-producing Klebsiella pneumoniae

scientific article published on 06 July 2019

CytoMatrix for a reliable and simple characterization of lung cancer stem cells from malignant pleural effusions

scientific article published on 09 August 2019

ErbB3 Phosphorylation as Central Event in Adaptive Resistance to Targeted Therapy in Metastatic Melanoma: Early Detection in CTCs during Therapy and Insights into Regulation by Autocrine Neuregulin

artículo científico publicado en 2019

ErbB3 plays a key role in the early phase of establishment of resistance to BRAF and/or MEK inhibitors

artículo científico publicado en 2015

Identification and Targeting of Stem Cell-Activated Pathways in Cancer Therapy

scientific article published on 04 June 2019

Immunotherapy Bridge 2017 and Melanoma Bridge 2017: meeting abstracts

artículo científico publicado en 2018

In Vitro Biophysical and Biological Characterization of Lipid Nanoparticles Co-Encapsulating Oncosuppressors miR-199b-5p and miR-204-5p as Potentiators of Target Therapy in Metastatic Melanoma

artículo científico publicado en 2020

Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma

artículo científico publicado en 2018

Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015

artículo científico publicado en 2016

Metronomic Chemotherapy with Vinorelbine Produces Clinical Benefit and Low Toxicity in Frail Elderly Patients Affected by Advanced Non-Small Cell Lung Cancer

article

MicroRNAs in melanoma development and resistance to target therapy

artículo científico publicado en 2017

Reprogramming miRNAs global expression orchestrates development of drug resistance in BRAF mutated melanoma

scientific article published on 25 September 2018

The potential of BRAF-associated non-coding RNA as a therapeutic target in melanoma

scientific article published on 09 December 2018

The promise of anti-ErbB3 monoclonals as new cancer therapeutics

artículo científico publicado el 1 de agosto de 2012

miR-579-3p controls melanoma progression and resistance to target therapy

artículo científico publicado en 2016