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A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity.

artículo científico publicado en 2016

A Small-Molecule SIRT2 Inhibitor That Promotes K-Ras4a Lysine Fatty-Acylation

scientific article published on 25 February 2019

Bortezomib Sensitizes Human Acute Myeloid Leukemia Cells to All-Trans-Retinoic Acid–Induced Differentiation by Modifying the RARα/STAT1 Axis ⬇️

artículo científico publicado el 13 de diciembre de 2012

Involvement of mitogen‐activated protein kinase in signal transducer and activator of transcription‐1 mediated differentiation induced by bortezomib in acute myeloid leukemia cells ⬇️

artículo científico publicado el 17 de octubre de 2011

Lessons learned from a SIRT2-selective inhibitor

artículo científico publicado en 2016

MEK/ERK Dependent Activation of STAT1 Mediates Dasatinib-Induced Differentiation of Acute Myeloid Leukemia ⬇️

artículo científico publicado el 25 de junio de 2013

Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis

scientific article published on 01 June 2019

SIRT2 and Lysine Fatty Acylation Regulate the Activity of RalB and Cell Migration

scientific article published on 03 September 2019

SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a.

artículo científico publicado en 2017

Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo

article

Suppression of Hypoxia-Inducible Factor 1α (HIF-1α) by Tirapazamine Is Dependent on eIF2α Phosphorylation Rather Than the mTORC1/4E-BP1 Pathway ⬇️

artículo científico publicado el 9 de noviembre de 2010

The Substrate Specificity of Sirtuins

artículo científico publicado en 2016

The ubiquitin-proteasome pathway plays essential roles in ATRA-induced leukemia cells G0/G1phase arrest and transition into granulocytic differentiation ⬇️

artículo científico publicado el 1 de diciembre de 2010

Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions

artículo científico publicado en 2020

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