Lista de obras -

A 12-week, randomized, double-blind, placebo-controlled, four-arm dose-finding phase 2 study evaluating bexagliflozin as monotherapy for adults with type 2 diabetes

scientific article published on 11 December 2019

A 24-week, randomized, double-blind, active-controlled clinical trial comparing bexagliflozin with sitagliptin as an adjunct to metformin for the treatment of type 2 diabetes in adults

scientific article published on 30 June 2019

A 96-week, multinational, randomized, double-blind, parallel-group, clinical trial evaluating the safety and effectiveness of bexagliflozin as a monotherapy for adults with type 2 diabetes

scientific article published on 08 August 2019

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

artículo científico publicado en 2002

A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies

artículo científico publicado en 2006

ABCA12 maintains the epidermal lipid permeability barrier by facilitating formation of ceramide linoleic esters

artículo científico publicado en 2008

ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol

artículo científico publicado en 2006

ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities

artículo científico publicado en 2004

Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.

artículo científico publicado en 2004

Activation of signaling pathways by putative scavenger receptor class A (SR-A) ligands requires CD14 but not SR-A ⬇️

artículo científico publicado el 17 de octubre de 2003

Atherosclerosis and innate immune signaling.

artículo científico publicado en 2005

C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway

artículo científico publicado en 2002

CD36 mediates the innate host response to beta-amyloid

artículo científico publicado en 2003

Case 22-2019: A 65-Year-Old Woman with Myopathy. Reply

artículo científico publicado en 2019

Case 22-2019: A 65-Year-Old Woman with Weakness, Dark Urine, and Dysphagia

artículo científico publicado en 2019

Cellular Activation, Phagocytosis, and Bactericidal Activity Against Group B Streptococcus Involve Parallel Myeloid Differentiation Factor 88-Dependent and Independent Signaling Pathways

scientific article published on 01 October 2002

Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1.

artículo científico publicado en 2004

Distinct roles of pattern recognition receptors CD14 and Toll-like receptor 4 in acute lung injury

artículo científico publicado en 2005

Effect of Patiromer on Serum Potassium Level in Patients With Hyperkalemia and Diabetic Kidney Disease: The AMETHYST-DN Randomized Clinical Trial

artículo científico

Efficacy and safety of the coadministration of ezetimibe with fenofibrate in patients with mixed hyperlipidaemia

artículo científico publicado en 2005

Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.

artículo científico publicado en 2013

Exome sequencing in suspected monogenic dyslipidemias

artículo científico publicado en 2015

Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association

artículo científico publicado en 2015

Generalized rank tests for replicated microarray data

artículo científico publicado en 2005

Genetic etiology of isolated low HDL syndrome: incidence and heterogeneity of efflux defects

artículo científico publicado en 2007

High-density lipoprotein-mediated cholesterol efflux capacity is improved by treatment with antiretroviral therapy in acute human immunodeficiency virus infection

artículo científico publicado en 2014

Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment

scientific article published on 01 July 2005

Local Injection of Bevacizumab (Avastin) and Angiolytic KTP Laser Treatment of Recurrent Respiratory Papillomatosis of the Vocal Folds: A Prospective Study ⬇️

artículo científico publicado el 1 de octubre de 2011

Long-term effects of patiromer for hyperkalaemia treatment in patients with mild heart failure and diabetic nephropathy on angiotensin-converting enzymes/angiotensin receptor blockers: results from AMETHYST-DN

artículo científico publicado en 2018

Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice

scientific article published on 23 October 2008

Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

artículo científico publicado en 2005

NIH Centers for Accelerated Innovations Program: principles, practices, successes and challenges

artículo científico publicado en 2017

Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I

artículo científico publicado en 2002

Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice

artículo científico publicado en 2002

Nonparametric methods for microarray data based on exchangeability and borrowed power

artículo científico publicado en 2005

Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home

artículo científico publicado en 2002

Patiromer induces rapid and sustained potassium lowering in patients with chronic kidney disease and hyperkalemia

artículo científico publicado en 2015

Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux

artículo científico publicado en 2005

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

artículo científico publicado en 2004

Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis

artículo científico publicado en 2004

Risk factors for coronary artery disease in patients with elevated high-density lipoprotein cholesterol

artículo científico publicado en 2006

SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter

scientific journal article

Safety and Effectiveness of Bexagliflozin in Patients With Type 2 Diabetes Mellitus and Stage 3a/3b CKD

artículo científico publicado en 2019

Safety and dosing of bevacizumab (avastin) for the treatment of recurrent respiratory papillomatosis

artículo científico publicado en 2012

Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages

artículo científico publicado en 2002

Scavenger receptors in atherosclerosis: beyond lipid uptake

artículo científico publicado en 2006

Statins, cholesterol, and the prevention of coronary heart disease

artículo científico publicado en 2006

Targeting Innate Immunity for CV Benefit

artículo científico publicado en 2008

The Creating an Optimal Warfarin Nomogram (CROWN) Study ⬇️

artículo científico publicado el 24 de noviembre de 2011

The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades

artículo científico publicado en 2004

US immigration order strikes against biotech.

artículo científico publicado en 2017

Wild type and Tangier disease ABCA1 mutants modulate cellular amyloid-β production independent of cholesterol efflux activity

artículo científico publicado en 2011

eLiXiRs for restraining inflammation

artículo científico publicado en 2003

Lista de obras de

A 12-week, randomized, double-blind, placebo-controlled, four-arm dose-finding phase 2 study evaluating bexagliflozin as monotherapy for adults with type 2 diabetes

A 24-week, randomized, double-blind, active-controlled clinical trial comparing bexagliflozin with sitagliptin as an adjunct to metformin for the treatment of type 2 diabetes in adults

A 96-week, multinational, randomized, double-blind, parallel-group, clinical trial evaluating the safety and effectiveness of bexagliflozin as a monotherapy for adults with type 2 diabetes

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies

ABCA12 maintains the epidermal lipid permeability barrier by facilitating formation of ceramide linoleic esters

ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol

ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities

Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.

Activation of signaling pathways by putative scavenger receptor class A (SR-A) ligands requires CD14 but not SR-A ⬇️

Atherosclerosis and innate immune signaling.

C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway

CD36 mediates the innate host response to beta-amyloid

Case 22-2019: A 65-Year-Old Woman with Myopathy. Reply

Case 22-2019: A 65-Year-Old Woman with Weakness, Dark Urine, and Dysphagia

Cellular Activation, Phagocytosis, and Bactericidal Activity Against Group B Streptococcus Involve Parallel Myeloid Differentiation Factor 88-Dependent and Independent Signaling Pathways

Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1.

Distinct roles of pattern recognition receptors CD14 and Toll-like receptor 4 in acute lung injury

Effect of Patiromer on Serum Potassium Level in Patients With Hyperkalemia and Diabetic Kidney Disease: The AMETHYST-DN Randomized Clinical Trial

Efficacy and safety of the coadministration of ezetimibe with fenofibrate in patients with mixed hyperlipidaemia

Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.

Exome sequencing in suspected monogenic dyslipidemias

Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association

Generalized rank tests for replicated microarray data

Genetic etiology of isolated low HDL syndrome: incidence and heterogeneity of efflux defects

High-density lipoprotein-mediated cholesterol efflux capacity is improved by treatment with antiretroviral therapy in acute human immunodeficiency virus infection

Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment

Local Injection of Bevacizumab (Avastin) and Angiolytic KTP Laser Treatment of Recurrent Respiratory Papillomatosis of the Vocal Folds: A Prospective Study ⬇️

Long-term effects of patiromer for hyperkalaemia treatment in patients with mild heart failure and diabetic nephropathy on angiotensin-converting enzymes/angiotensin receptor blockers: results from AMETHYST-DN

Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice

Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

NIH Centers for Accelerated Innovations Program: principles, practices, successes and challenges

Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I

Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice

Nonparametric methods for microarray data based on exchangeability and borrowed power

Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home

Patiromer induces rapid and sustained potassium lowering in patients with chronic kidney disease and hyperkalemia

Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis

Risk factors for coronary artery disease in patients with elevated high-density lipoprotein cholesterol

SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter

Safety and Effectiveness of Bexagliflozin in Patients With Type 2 Diabetes Mellitus and Stage 3a/3b CKD

Safety and dosing of bevacizumab (avastin) for the treatment of recurrent respiratory papillomatosis

Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages

Scavenger receptors in atherosclerosis: beyond lipid uptake

Statins, cholesterol, and the prevention of coronary heart disease

Targeting Innate Immunity for CV Benefit

The Creating an Optimal Warfarin Nomogram (CROWN) Study ⬇️

The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades

US immigration order strikes against biotech.

Wild type and Tangier disease ABCA1 mutants modulate cellular amyloid-β production independent of cholesterol efflux activity

eLiXiRs for restraining inflammation