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Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

scientific article published on 23 December 2020

Afucosylated immunoglobulin G responses are a hallmark of enveloped virus infections and show an exacerbated phenotype in COVID-19

artículo científico publicado en 2020

An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability

artículo científico publicado en 2016

Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike

artículo científico publicado en 2015

Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer

artículo científico publicado en 2015

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.

artículo científico publicado en 2017

Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer

artículo científico publicado en 2016

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

artículo científico publicado en 2017

Functional Attributes of Antibodies, Effector Cells, and Target Cells Affecting NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity

scientific article published on 20 November 2019

Glycine 236 in the Lower Hinge Region of Human IgG1 Differentiates FcγR from Complement Effector Function

artículo científico publicado en 2020

HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds

artículo científico publicado en 2016

IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming

artículo científico publicado en 2020

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization

artículo científico publicado en 2017

Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

artículo científico publicado en 2015

Neutralizing antibody responses induced by HIV-1 envelope glycoprotein SOSIP trimers derived from elite neutralizers

artículo científico publicado en 2020

Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers

artículo científico publicado en 2017