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50 Years Ago in The Journal of Pediatrics: The Effect of Arginine Infusion on Plasma Growth Hormone and Insulin in Children

scientific article published on 01 February 2019

560 STUDIES OF H-Y ANTIGEN IN A 46, XYp- PHENOTYPIC FEMALE WITH TURNER STIGMATA AND UNDIFFERENTIATED GONADS

artículo científico publicado en 1978

A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production

artículo científico publicado en 2016

A Novel Homozygous Mutation of the Acid-Labile Subunit (IGFALS) Gene in a Male Adolescent

scientific article published on 05 February 2019

A Novel Mutation in Insulin-Like Growth Factor 1 Receptor (c.641-2A>G) Is Associated with Impaired Growth, Hypoglycemia, and Modified Immune Phenotypes

artículo científico publicado en 2020

A SHOX to the system

scientific article published on 01 December 2001

A Successful HSCT in a Girl with Novel LRBA Mutation with Refractory Celiac Disease

artículo científico publicado en 2015

A database and website for molecular defects of the GH-IGF axis: www.growthgenetics.com

artículo científico publicado en 2013

A kinase-mediated regulation of granulosa cell-derived insulin-like growth factor binding proteins (IGFBPs): disparate response sensitivities of distinct IGFBP species ⬇️

artículo científico publicado el 1 de abril de 1993

A mutant signal transducer and activator of transcription 5b, associated with growth hormone insensitivity and insulin-like growth factor-I deficiency, cannot function as a signal transducer or transcription factor

artículo científico publicado en 2006

A novel ERCC6 splicing variant associated with a mild Cockayne syndrome phenotype

artículo científico publicado en 2014

A novel GHR intronic variant, c.266+83G>T , activates a cryptic 5' splice site causing severe GHR deficiency and classical GH insensitivity syndrome

artículo científico publicado en 2013

A novel Y332C missense mutation in the intracellular domain of the human growth hormone receptor does not alter STAT5b signaling: redundancy of GHR intracellular tyrosines involved in STAT5b signaling

scientific article published on 21 October 2010

A novel exonic GHR splicing mutation (c.784G > C) in a patient with classical growth hormone insensitivity syndrome

artículo científico publicado en 2012

A novel insulin-like growth factor (IGF)-independent role for IGF binding protein-3 in mesenchymal chondroprogenitor cell apoptosis

artículo científico publicado en 2003

A novel missense mutation in the SH2 domain of the STAT5B gene results in a transcriptionally inactive STAT5b associated with severe IGF-I deficiency, immune dysfunction, and lack of pulmonary disease

scientific article published on 14 March 2012

A novel variant in CDKN1C is associated with intrauterine growth restriction, short stature, and early-adulthood-onset diabetes

artículo científico publicado en 2014

A prospective, randomized study of testosterone treatment of constitutional delay of growth and development in male adolescents.

artículo científico publicado en 1982

A randomized, double blind, placebo-controlled trial on safety and efficacy of recombinant human insulin-like growth factor-I in children with growth hormone receptor deficiency

artículo científico publicado en 1995

A simple assay for proteolysis of IGFBP-3.

artículo científico publicado en 1991

Aberrant folding of a mutant Stat5b causes growth hormone insensitivity and proteasomal dysfunction

artículo científico publicado en 2005

Abnormal GH receptor signaling in children with idiopathic short stature

artículo científico publicado en 2001

Acid-labile subunit (ALS) deficiency.

artículo científico publicado en 2011

Acromegaly and Zollinger-Ellison syndrome secondary to an islet cell tumor: characterization and quantification of plasma and tumor human growth hormone-releasing factor

artículo científico publicado en 1984

Activin-attenuated expression of transcripts encoding granulosa cell-derived insulin-like growth factor binding proteins 4 and 5 in the rat: a putative antiatretic effect

artículo científico publicado en 1997

Acute somatomedin response to growth hormone: radioreceptor assay versus radioimmunoassay

scientific article published on 01 April 1981

Administration of growth hormone (GH), but not insulin-like growth factor-I (IGF-I), by continuous infusion can induce the formation of the 150-kilodalton IGF-binding protein-3 complex in GH-deficient rats

scientific article published on 01 May 1994

Advanced glycosylation end products up-regulate connective tissue growth factor (insulin-like growth factor-binding protein-related protein 2) in human fibroblasts: a potential mechanism for expansion of extracellular matrix in diabetes mellitus

scientific article published on 01 May 2001

Aging alters somatomedin-C-dexamethasone synergism in the stimulation of deoxyribonucleic acid synthesis and replication of cultured human fibroblasts

artículo científico publicado en 1985

Alteration in insulin-like growth factor-binding proteins (IGFBPs) and IGFBP-3 protease activity in serum and urine from acute and chronic renal failure

artículo científico publicado en 1994

Antiproliferative actions of insulin-like growth factor binding protein (IGFBP)-3 in human breast cancer cells.

artículo científico

Antiproliferative effects of insulin-like growth factor-binding protein-3 in mesenchymal chondrogenic cell line RCJ3.1C5.18. relationship to differentiation stage

artículo científico publicado en 2000

Assays for insulin-like growth factors and their binding proteins: practicalities and pitfalls

scientific article published on 01 May 1996

Atypical GH insensitivity syndrome and severe insulin-like growth factor-I deficiency resulting from compound heterozygous mutations of the GH receptor, including a novel frameshift mutation affecting the intracellular domain

artículo científico publicado en 2010

Binding and internalization of insulin and insulin-like growth factors by isolated brain microvessels

artículo científico publicado en 1986

Binding properties and distribution of insulin-like growth factor binding protein-related protein 3 (IGFBP-rP3/NovH), an additional member of the IGFBP Superfamily

artículo científico publicado en 1999

Binding properties of insulin-like growth factor binding protein-3 (IGFBP-3), IGFBP-3 N- and C-terminal fragments, and structurally related proteins mac25 and connective tissue growth factor measured using a biosensor

artículo científico publicado en 2002

Biochemical analysis of prostate specific antigen-proteolyzed insulin-like growth factor binding protein-3

scientific journal article

Biochemical diagnosis and management of corticosterone methyl oxidase type II deficiency

scientific article published on 01 January 1986

Biochemical diagnostic strategies in the evaluation of short stature: the diagnosis of insulin-like growth factor deficiency

artículo científico publicado en 1996

Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease

scientific journal article

Biosynthetic methionyl human growth hormones is biologically active in adult man

scientific article published on 01 June 1982

Body changes in adolescent patients with growth hormone receptor deficiency receiving recombinant human insulin-like growth factor I and luteinizing hormone-releasing hormone analogue: preliminary results

artículo científico publicado en 1994

Bone Mineral, Histomorphometry, and Body Composition in Adults with Growth Hormone Receptor Deficiency ⬇️

artículo científico publicado el 1 de marzo de 1998

Both human pituitary growth hormone and recombinant DNA-derived human growth hormone cause insulin resistance at a postreceptor site

artículo científico publicado en 1982

CTGF (IGFBP-rP2) is specifically expressed in malignant lymphoblasts of patients with acute lymphoblastic leukaemia (ALL).

artículo científico publicado en 2000

Carbohydrate and lipid metabolism in Turner syndrome: effect of therapy with growth hormone, oxandrolone, and a combination of both

artículo científico publicado en 1988

Cardiovascular evaluation in Turner syndrome: utility of MR imaging

artículo científico publicado el 1 de agosto de 1992

Challenges and future for the delivery of growth hormone therapy.

artículo científico publicado en 2017

Characterization and Hormonal Regulation of a Rat Ovarian Insulin-Like Growth Factor Binding Protein-5 Endopeptidase: An FSH-Inducible Granulosa Cell-Derived Metalloprotease* ⬇️

artículo científico publicado el 1 de marzo de 1998

Characterization and hormonal regulation of granulosa cell-derived insulin-like growth factor binding protein-4.

artículo científico publicado en 1996

Characterization of Insulin-Like Growth Factor Binding Proteins (IGFBPs) during Gestation in Mice: Effects of Hypophysectomy and an IGFBP-Specific Serum Protease Activity* ⬇️

artículo científico publicado el 1 de noviembre de 1990

Characterization of Insulin-Like Growth Factor I Receptors on Cultured Rat Bone Cells: Regulation of Receptor Concentration by Glucocorticoids* ⬇️

artículo científico publicado el 1 de octubre de 1984

Characterization of a Specific Receptor for Somatomedin C (SM-C) on Cultured Human Lymphocytes: Evidence that SM-C Modulates Homologous Receptor Concentration* ⬇️

artículo científico publicado el 1 de diciembre de 1980

Characterization of a low molecular mass form of insulin-like growth factor binding protein-3 (17.7 kilodaltons) in urine and serum from healthy children and growth hormone (GH)-deficient patients: relationship with GH therapy

artículo científico publicado en 1995

Characterization of a specific insulin-like growth factor-I/somatomedin-C receptor on high density, primary monolayer cultures of bovine articular chondrocytes: regulation of receptor concentration by somatomedin, insulin and growth hormone

artículo científico publicado en 1985

Characterization of an insulin-like growth factor binding protein-5 protease produced by rat articular chondrocytes and a neuroblastoma cell line.

artículo científico publicado en 1996

Characterization of high affinity receptors for insulin-like growth factors I and II on rat anterior pituitary cells

artículo científico publicado en 1984

Characterization of insulin, insulin-like growth factors I and II, and growth hormone receptors on human leukemic lymphoblasts

artículo científico publicado en 1986

Characterization of insulin-like growth factor binding protein-3 (IGFBP-3) binding to human breast cancer cells: kinetics of IGFBP-3 binding and identification of receptor binding domain on the IGFBP-3 molecule

scientific article published on 01 March 1999

Characterization of insulin-like growth factor binding proteins from human breast cancer cells

artículo científico publicado en 1989

Characterization of insulin-like growth factor binding proteins of cultured rat astroglial and neuronal cells

artículo científico publicado en 1989

Characterization of insulin-like growth factor-I/somatomedin-C receptors on human keratinocyte monolayers

scientific article published on 01 August 1986

Characterization of insulin-like growth factor-binding protein-related protein-1 in prostate cells

artículo científico publicado en 1998

Characterization of insulin-like growth factor-binding protein-related proteins (IGFBP-rPs) 1, 2, and 3 in human prostate epithelial cells: potential roles for IGFBP-rP1 and 2 in senescence of the prostatic epithelium

artículo científico publicado en 2000

Characterization of insulin-like growth factor-binding proteins in cultured rat pituitary cells.

artículo científico publicado en 1989

Characterization of the Somatomedin-C/Insulin-Like Growth Factor I (SM-C/IGF-I) Receptor on Cultured Human Fibroblast Monolayers: Regulation of Receptor Concentrations by SM-C/IGF-I and Insulin* ⬇️

artículo científico publicado el 1 de septiembre de 1982

Characterization of the affinities of insulin-like growth factor (IGF)-binding proteins 1-4 for IGF-I, IGF-II, IGF-I/insulin hybrid, and IGF-I analogs ⬇️

artículo científico publicado el 1 de marzo de 1993

Characterization of the insulin-like growth factors (IGF) axis in a cultured mouse Leydig cell line (TM-3)

artículo científico publicado el 1 de septiembre de 1995

Characterization of urinary insulin-like growth factor binding proteins

artículo científico publicado el 1 de abril de 1992

Circulating ghrelin levels are suppressed by meals and octreotide therapy in children with Prader-Willi syndrome

artículo científico publicado en 2003

Circulating growth hormone binding proteins

artículo científico publicado en 1994

Clinical and biochemical characteristics of growth hormone receptor deficiency (Laron syndrome).

artículo científico publicado en 1992

Clinical and endocrine characteristics in atypical and classical growth hormone insensitivity syndrome

artículo científico publicado en 2001

Clinical aspects of insulin-like growth factor binding proteins

artículo científico publicado el 1 de enero de 1991

Clinical features and endocrine status in patients with growth hormone insensitivity (Laron syndrome)

artículo científico publicado en 1993

Clinical uses of synthetic growth hormone

artículo científico publicado en 1983

Clinical utility of insulin-like growth factor assays.

artículo científico publicado en 1987

Collection of blood in heparinized tubes does not alter the molecular distribution or forms of IGFBP-3 and IGF ⬇️

artículo científico publicado el 1 de agosto de 1996

Comparative effects of somatomedin C and insulin on the metabolism and growth of cultured human fibroblasts

scientific article published on 01 January 1985

Compartmentalization of Human Growth Hormone by Cultured Human Lymphocytes* ⬇️

artículo científico publicado el 1 de agosto de 1980

Compliance and persistence in pediatric and adult patients receiving growth hormone therapy

artículo científico publicado en 2008

Concentrations of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3), IGF, and IGFBP-3 protease activity in cerebrospinal fluid of children with leukemia, central nervous system tumor, or meningitis

artículo científico publicado en 1993

Connective tissue growth factor/IGF-binding protein-related protein-2 is a mediator in the induction of fibronectin by advanced glycosylation end-products in human dermal fibroblasts

artículo científico publicado en 2002

Constancy of somatomedin response to growth hormone treatment of hypopituitary dwarfism, and lack of correlation with growth rate

artículo científico publicado en 1981

Current Issues on Molecular Diagnosis of GH Signaling Defects ⬇️

artículo científico publicado el 1 de enero de 2013

Cutting edge: Decreased accumulation and regulatory function of CD4+ CD25(high) T cells in human STAT5b deficiency

artículo científico publicado en 2006

Decreased expression of Wilms' tumor gene WT-1 and elevated expression of insulin growth factor-II (IGF-II) and type 1 IGF receptor genes in prostatic stromal cells from patients with benign prostatic hyperplasia

scientific article published on 01 July 1997

Decreased serum insulin-like growth factor-I associated with growth failure in newborn lambs with experimental cyanotic heart disease ⬇️

artículo científico publicado el 1 de abril de 1992

Decreased ternary complex formation and predominance of a 29 kDa IGFBP-3 fragment in human fetal serum

artículo científico publicado el 1 de junio de 1994

Defects in growth hormone receptor signaling

scientific article published on 27 March 2007

Demonstration and structural comparison of receptors for insulin-like growth factor-I and -II (IGF-I and -II) in brain and blood-brain barrier

artículo científico publicado en 1987

Demonstration of insulin-like growth factor (IGF-I and -II) receptors and binding protein in human breast cancer cell lines

artículo científico publicado en 1988

Demonstration of normal plasma somatomedin concentrations in cystic fibrosis

scientific article published on 01 August 1981

Demonstration of receptors for insulin-like growth factor binding protein-3 on Hs578T human breast cancer cells

artículo científico publicado en 1993

Density-associated loss of functional receptors for somatomedin-C/insulinlike growth factor I (SM-C/IGF-I) on cultured human fibroblast monolayers ⬇️

artículo científico publicado el 1 de noviembre de 1984

Development of additional pituitary hormone deficiencies in pediatric patients originally diagnosed with idiopathic isolated GH deficiency

artículo científico publicado en 2013

Development of additional pituitary hormone deficiencies in pediatric patients originally diagnosed with isolated growth hormone deficiency due to organic causes

artículo científico publicado en 2016

Developmental expression of insulin-like growth factor-II receptor immunoreactivity in the rat central nervous system

artículo científico publicado en 1990

Diagnosis and treatment of growth hormone deficiency in children and adolescents: towards a consensus. Ten years after the Availability of Recombinant Human Growth Hormone Workshop held in Pisa, Italy, 27-28 March 1998

artículo científico publicado en 1998

Diagnosis of intra-amniotic infection by proteomic profiling and identification of novel biomarkers

artículo científico publicado en 2004

Diagnosis, Genetics, and Therapy of Short Stature in Children: A Growth Hormone Research Society International Perspective

artículo científico publicado en 2019

Diagnostic controversy: the diagnosis of childhood growth hormone deficiency revisited

artículo científico publicado en 1995

Different molecular and messenger ribonucleic acid forms of insulin-like growth factor-binding protein-3 in the pregnant baboon (Papio anubis)

artículo científico publicado en 1995

Differential Regulation of the Insulin-Like Growth Factors (IGF-I and -II) and IGF Binding Proteins During Malnutrition in the Neonatal Rat* ⬇️

artículo científico publicado el 1 de julio de 1991

Differential activation of the IGF binding protein-3 promoter by butyrate in prostate cancer cells

artículo científico publicado en 2002

Differential binding of 125I-IGF-I preparations to human fibroblast monolayers

artículo científico publicado en 1988

Differential effects of insulin-like growth factor (IGF)-I and IGF-II on the expression of IGF binding proteins (IGFBPs) in a rat neuroblastoma cell line: isolation and characterization of two forms of IGFBP-4.

artículo científico publicado en 1991

Differential effects of insulin-like growth factor (IGF)-binding protein-3 and its proteolytic fragments on ligand binding, cell surface association, and IGF-I receptor signaling

artículo científico publicado en 2000

Differentiating the roles of STAT5B and STAT5A in human CD4+ T cells.

artículo científico publicado en 2013

Direct evidence that the insulin receptor mediates a mitogenic response in cultured human fibroblasts

artículo científico publicado en 1989

Distribution of insulin-like growth factor II receptor immunoreactivity in rat tissues

artículo científico publicado en 1988

Does the GH-IGF axis play a role in cancer pathogenesis?

artículo científico publicado en 2000

Dominant-negative STAT5B mutations cause growth hormone insensitivity with short stature and mild immune dysregulation.

artículo científico publicado en 2018

Dose-sparing and safety-enhancing effects of an IGF-I-based dosing regimen in short children treated with growth hormone in a 2-year randomized controlled trial: therapeutic and pharmacoeconomic considerations

artículo científico publicado en 2014

Early, discontinuous, high dose growth hormone treatment to normalize height and weight of short children born small for gestational age: results over 6 years

artículo científico publicado en 1999

Editorial: The Blind Men and the Elephant—A Parable for the Study of Insulin-Like Growth Factor Binding Proteins ⬇️

artículo científico publicado el 1 de enero de 1998

Editorial: the pharmacogenomics of human growth

artículo científico publicado en 2006

Effect of IGFBP-3 on IGF- and IGF-analogue-induced insulin-like growth factor-I receptor (IGFIR) signalling ⬇️

artículo científico publicado el 1 de agosto de 2001

Effect of an anti-insulin-like growth factor I receptor antibody on insulin-like growth factor II stimulation of DNA synthesis in human fibroblasts

artículo científico publicado en 1986

Effects of Dose and Gender on the Growth and Growth Factor Response to GH in GH-Deficient Children: Implications for Efficacy and Safety ⬇️

artículo científico publicado el 1 de enero de 2002

Effects of continuous infusion of insulin-like growth factor I and II, alone and in combination with thyroxine or growth hormone, on the neonatal hypophysectomized rat

artículo científico publicado el 1 de enero de 1992

Effects of elevated serum insulinlike growth factor-II on growth hormone and insulinlike growth factor-I mRNA and secretion

artículo científico publicado en 1989

Effects of estrogen on growth hormone following clonidine stimulation.

artículo científico publicado en 1993

Effects of growth hormone on pulmonary function, sleep quality, behavior, cognition, growth velocity, body composition, and resting energy expenditure in Prader-Willi syndrome

artículo científico publicado en 2003

Effects of growth hormone therapy and malnutrition on the growth of rats with renal failure

artículo científico publicado en 1988

Effects of insulin-like growth factors (IGFs) and IGF receptor antibodies on the proliferation of human breast cancer cells

artículo científico publicado el 1 de enero de 1992

Effects of insulin‐like growth factor I treatment on the molecular distribution of insulin‐like growth factors among different binding proteins ⬇️

artículo científico publicado el 1 de abril de 1994

Effects of sodium butyrate on expression of members of the IGF-binding protein superfamily in human mammary epithelial cells

artículo científico publicado en 2001

Effects of testosterone therapy for pubertal delay

artículo científico publicado en 1988

Efficacy of IGF‐based growth hormone (GH) dosing in nonGH‐deficient (nonGHD) short stature children with low IGF‐I is not related to basal IGF‐I levels ⬇️

artículo científico publicado el 1 de marzo de 2013

Efficacy of insulin-like growth factor I levels in predicting the response to provocative growth hormone testing

artículo científico publicado en 1990

Elevated levels of insulin-like growth factor-binding protein-2 in the serum of prostate cancer patients ⬇️

artículo científico publicado el 1 de abril de 1993

Evaluation of the components of insulin-like growth factor (IGF)-IGF binding protein (IGFBP) system in adolescents with type 1 diabetes and persistent microalbuminuria: relationship with increased urinary excretion of IGFBP-3 18 kD N-terminal fragme

artículo científico publicado en 1999

Evidence for a continuum of genetic, phenotypic, and biochemical abnormalities in children with growth hormone insensitivity.

artículo científico publicado en 2011

Evidence for insulin-like growth factor (IGF)-independent transcriptional regulation of IGF binding protein-3 by growth hormone in SKHEP-1 human hepatocarcinoma cells

scientific article published on 01 April 1997

Evidence for pituitary regulation of somatic growth, insulin-like growth factors-I and -II, and their binding proteins in the fetal rat.

artículo científico publicado en 1993

Expanding Genetic and Functional Diagnoses of IGF1R Haploinsufficiencies

artículo científico publicado en 2017

Expression and down-regulation by retinoic acid of IGF binding protein-2 and -4 in medium from human neuroblastoma cells.

artículo científico publicado en 1994

Expression of a lactogen-dependent insulin-like growth factor-binding protein in cultured mouse mammary epithelial cells

artículo científico publicado el 1 de julio de 1992

Expression of serum insulin-like growth factors, insulin-like growth factor-binding proteins, and the growth hormone-binding protein in heterozygote relatives of Ecuadorian growth hormone receptor deficient patients

artículo científico publicado el 1 de abril de 1992

Expression of the BRL-3A insulin-like growth factor binding protein (rBP-30) in the rat central nervous system

artículo científico publicado en 1989

Expression of two insulin-like growth factor-binding proteins in a human endometrial cancer cell line: structural, immunological, and genetic characterization

artículo científico publicado en 1989

Extreme elevation of serum growth hormone-binding protein concentrations resulting from a novel heterozygous splice site mutation of the growth hormone receptor gene

artículo científico publicado en 2009

Factors predicting the response to growth hormone (GH) therapy in prepubertal children with GH deficiency

artículo científico publicado en 1993

Familial Short Stature Caused by Haploinsufficiency of The Insulin-like Growth Factor 1 Receptor Due to Nonsense-Mediated mRNA Decay

artículo científico publicado en 2009

Familial precocious puberty associated with isolated elevation of luteinizing hormone

scientific article published on 01 October 1980

Familial short stature caused by haploinsufficiency of the insulin-like growth factor i receptor due to nonsense-mediated messenger ribonucleic acid decay

artículo científico publicado en 2009

Fasting affects serum insulin-like growth factors (IGFs) and IGF-binding proteins differently in patients with noninsulin-dependent diabetes mellitus versus healthy nonobese and obese subjects

artículo científico

First-year response to rhGH therapy in children with CKD: a National Cooperative Growth Study Report

artículo científico publicado en 2010

Follicle-stimulating hormone inhibits the constitutive release of insulin-like growth factor binding proteins by cultured rat ovarian granulosa cells

artículo científico publicado en 1990

Foreword from the editors

artículo científico publicado en 2016

Foreword from the guest editors

scientific article published on 01 August 2020

Foreword from the guest editors.

artículo científico publicado en 2017

Further Delineation of Aortic Dilation, Dissection, and Rupture in Patients With Turner Syndrome ⬇️

artículo científico publicado el 1 de julio de 1998

Further characterization of the keratinocyte somatomedin-C/insulin-like growth factor I (SM-C/IGF-I) receptor and the biological responsiveness of cultured keratinocytes to SM-C/IGF-I

scientific article published on 01 January 1988

Gender differences in height: an evolutionary perspective

artículo científico publicado en 2004

Generation and characterization of an IGFBP-7 antibody: identification of 31kD IGFBP-7 in human biological fluids and Hs578T human breast cancer conditioned media

artículo científico publicado en 1997

Generation of anti-insulin-like growth factor-binding protein-related protein 1 (IGFBP-rP1/MAC25) monoclonal antibodies and immunoassay: quantification of IGFBP-rP1 in human serum and distribution in human fluids and tissues

artículo científico publicado en 2003

Genetic Defects in the Growth Hormone-IGF-I Axis Causing Growth Hormone Insensitivity and Impaired Linear Growth

artículo científico publicado en 2011

Genetic causes of growth hormone insensitivity beyond GHR

artículo científico publicado en 2020

Genetic defects of the growth hormone-insulin-like growth factor axis

artículo científico publicado en 2000

Genetic evaluation of short stature.

artículo científico publicado en 2014

Growth Hormone Insensitivity Syndromes: Lessons Learned and Opportunities Missed ⬇️

artículo científico publicado el 1 de enero de 2001

Growth Hormone Research Society perspective on biomarkers of GH action in children and adults.

artículo científico publicado en 2018

Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations

artículo científico publicado en 2016

Growth and intellectual development

artículo científico publicado en 1986

Growth hormone (GH) insensitivity and insulin-like growth factor-I deficiency in Inuit subjects and an Ecuadorian cohort: functional studies of two codon 180 GH receptor gene mutations

artículo científico publicado en 2007

Growth hormone (GH) insensitivity due to primary GH receptor deficiency

artículo científico publicado en 1994

Growth hormone insensitivity

artículo científico publicado en 1997

Growth hormone insensitivity and severe short stature in siblings: a novel mutation at the exon 13-intron 13 junction of the STAT5b gene

artículo científico publicado en 2007

Growth hormone insensitivity associated with a STAT5b mutation

artículo científico publicado en 2003

Growth hormone insensitivity resulting from post-GH receptor defects

artículo científico publicado en 2004

Growth hormone insensitivity syndromes

scientific article published on 01 September 1995

Growth hormone insensitivity.

artículo científico publicado en 1997

Growth hormone mediates the growth of T-lymphoblast cell lines via locally generated insulin-like growth factor-I.

artículo científico publicado en 1990

Growth hormone receptor deficiency (Laron syndrome): clinical and genetic characteristics

artículo científico publicado en 1991

Growth hormone receptor deficiency in Ecuador

artículo científico publicado en 1999

Growth hormone receptor deficiency in Ecuador: clinical and biochemical phenotype in two populations ⬇️

artículo científico publicado el 1 de febrero de 1993

Growth hormone replacement therapy during transition of patients with childhood-onset growth hormone deficiency into adulthood: what are the issues?

artículo científico publicado en 1998

Growth hormone therapy in hypophosphatemic rickets

scientific article published on 01 October 1991

Growth hormone therapy of Turner syndrome: the impact of age of estrogen replacement on final height. Genentech, Inc., Collaborative Study Group

artículo científico publicado en 2000

Growth hormone therapy of Turner's syndrome: Beneficial effect on adult height ⬇️

artículo científico publicado el 1 de febrero de 1998

Growth hormone treatment in the United States: demographic and diagnostic features of 2331 children

artículo científico publicado en 1990

Growth hormone treatment of short children born small for gestational age: growth responses with continuous and discontinuous regimens over 6 years

artículo científico publicado en 2000

Growth in growth hormone insensitivity

scientific article published on 01 September 1994

Heart rate increases in patients with growth hormone receptor deficiency treated with insulin-like growth factor I

scientific article published on 01 April 1994

Height Gain and Safety Outcomes in Growth Hormone-Treated Children with Idiopathic Short Stature: Experience from a Prospective Observational Study

artículo científico publicado en 2019

Height velocity targets from the national cooperative growth study for first-year growth hormone responses in short children

artículo científico publicado en 2007

Heterogeneity of insulin-like growth factor-I affinity for the insulin-like growth factor-II receptor: comparison of natural, synthetic and recombinant DNA-derived insulin-like growth factor-I.

artículo científico publicado en 1987

High-dose growth hormone treatment of short children born small for gestational age

artículo científico publicado en 1996

Hormonal and metabolic effects and pharmacokinetics of recombinant insulin-like growth factor-I in growth hormone receptor deficiency/Laron syndrome ⬇️

artículo científico publicado el 1 de julio de 1993

Hormonal control of the replication of human fetal fibroblasts: role of somatomedin C/insulin-like growth factor I.

artículo científico publicado en 1986

Human acid-labile subunit deficiency: clinical, endocrine and metabolic consequences.

scientific article published on September 2009

Human blood-brain barrier insulin-like growth factor receptor

artículo científico publicado en 1988

Hypertension caused by an aldosterone-secreting adenoma. Occurrence in a 7-year-old child

articulo cientifico

Hypoxia-lnduced Changes in Insulin-Like Growth Factors and Their Binding Proteins in Pregnant Rats ⬇️

artículo científico publicado el 1 de enero de 1997

IGF generation in short stature

artículo científico publicado en 2002

IGF-I in human growth: lessons from defects in the GH-IGF-I axis

artículo científico publicado en 2013

IGF-I stimulates granulosa cell-derived insulin-like growth factor binding protein-5: evidence for medication via type I IGF receptors

artículo científico publicado en 1994

IGF-II and IGF-binding proteins increase dramatically during rabbit pregnancy

scientific article published on 01 January 1996

IGFALS gene dosage effects on serum IGF-I and glucose metabolism, body composition, bone growth in length and width, and the pharmacokinetics of recombinant human IGF-I administration

artículo científico publicado en 2014

IGFBP-3 sensitizes prostate cancer cells to interferon-gamma-induced apoptosis

artículo científico publicado en 2007

IGFBPs and cancer.

artículo científico publicado en 2004

Identification and characterization of insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs), and IGFBP proteases in human synovial fluid

artículo científico publicado en 1996

Identification and management of poor response to growth-promoting therapy in children with short stature

artículo científico

Identification of Glycosylated 38-kDa Connective Tissue Growth Factor (IGFBP-Related Protein 2) and Proteolytic Fragments in Human Biological Fluids, and Up-Regulation of IGFBP-rP2 Expression by TGF-β in Hs578T Human Breast Cancer Cells ⬇️

artículo científico publicado el 1 de julio de 1998

Identification of Insulin-Like Growth Factor-Binding Protein-3 (IGFBP-3) and IGFBP-2 in Human Follicular Fluid* ⬇️

artículo científico publicado el 1 de noviembre de 1990

Identification of STAT-1 as a molecular target of IGFBP-3 in the process of chondrogenesis

artículo científico publicado en 2002

Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily ⬇️

artículo científico publicado el 25 de noviembre de 1997

Identification of a novel heterozygous IGF1 splicing mutation in a large kindred with familial short stature

scientific article published on 20 July 2012

Identification of insulin-like growth factor-binding protein-2 (IGF-BP-2) and a low molecular weight IGF-BP in human seminal plasma ⬇️

artículo científico publicado el 1 de febrero de 1990

Identification of insulin-like growth factor-binding protein-3 (IGFBP-3) fragments and IGFBP-5 proteolytic activity in human seminal plasma: a comparison of normal and vasectomized patients

artículo científico publicado en 1994

Identification of receptors for insulin-like growth factor II in two insulin-like growth factor II producing cell lines

artículo científico publicado en 1986

Identification of the first patient with a confirmed mutation of the JAK-STAT system.

artículo científico publicado en 2005

Idiopathic short stature: will genetics influence the choice between GH and IGF-I therapy?

artículo científico publicado en 2007

Immunoblot studies of the acid‐labile subunit (ALS) in biological fluids, normal human serum and in children with GH deficiency and GH receptor deficiency before and after long‐term therapy with GH or IGF‐I respectively ⬇️

artículo científico publicado el 1 de diciembre de 1997

Impact of heterozygosity for acid-labile subunit (IGFALS) gene mutations on stature: results from the international acid-labile subunit consortium.

artículo científico publicado en 2010

Impaired synergism between somatomedin C/insulin-like growth factor I and dexamethasone in the growth of fibroblasts from a patient with insulin resistance

artículo científico publicado en 1987

In Vivo Modulation of Somatomedin Receptor Sites: Effects of Growth Hormone Treatment of Hypopituitary Children* ⬇️

artículo científico publicado el 1 de abril de 1981

In vivo imaging of hepatic growth hormone signaling

artículo científico publicado en 2006

Increased proteolysis of insulin-like growth factor-binding protein-3 (IGFBP-3) in noninsulin-dependent diabetes mellitus serum, with elevation of a 29-kilodalton (kDa) glycosylated IGFBP-3 fragment contained in the approximately 130- to 150-kDa ter

artículo científico publicado en 1994

Inhibition of Insulin Receptor Activation by Insulin-like Growth Factor Binding Proteins ⬇️

artículo científico publicado el 5 de diciembre de 1997

Inhibitory effects of insulin-like growth factor (IGF)-binding proteins-1 and -3 on IGF-activated glucose consumption in mouse BALB/c 3T3 fibroblasts ⬇️

artículo científico publicado el 1 de marzo de 1993

Insulin and IGF Binding by IGFBP-3 Fragments Derived From Proteolysis, Baculovirus Expression and Normal Human Urine ⬇️

artículo científico publicado el 1 de abril de 1998

Insulin and insulin-like growth factor (somatomedin) receptors on cloned rat pituitary tumor cells

artículo científico publicado en 1985

Insulin growth factor-based dosing of growth hormone therapy in children: a randomized, controlled study

artículo científico publicado en 2007

Insulin resistance is associated with increased serum concentration of IGF-binding protein-related protein 1 (IGFBP-rP1/MAC25).

artículo científico publicado en 2006

Insulin-Like Growth Factor Binding Protein-3 Concentrations and Insulin-Like Growth Factor Binding Protein-3 Protease Activity in Sera of Patients with Malignant Solid Tumors or Leukemia ⬇️

artículo científico publicado el 1 de junio de 1994

Insulin-Like Growth Factor Binding Protein-I Levels Are Strongly Associated with Insulin Sensitivity and Obesity in Early Pubertal Children1 ⬇️

artículo científico publicado el 1 de junio de 1998

Insulin-Like Growth Factor Binding Proteins in Maternal Serum Throughout Gestation and in the Puerperium: Effects of a Pregnancy-Associated Serum Protease Activity* ⬇️

artículo científico publicado el 1 de octubre de 1990

Insulin-Like Growth Factor Binding Proteins: Structural and Molecular Relationships ⬇️

artículo científico publicado el 1 de enero de 1991

Insulin-Like Growth Factors (IGFs), IGF Receptors, and IGF-Binding Proteins in Primary Cultures of Prostate Epithelial Cells* ⬇️

artículo científico publicado el 1 de agosto de 1991

Insulin-induced Loss of Insulin-like Growth Factor-I Receptors on IM-9 Lymphocytes ⬇️

artículo científico publicado el 1 de mayo de 1982

Insulin-like Growth Factor-II (IGF-II) and IGF Binding Proteins in Human Endometrium ⬇️

artículo científico publicado el 1 de enero de 1991

Insulin-like growth factor (IGF) binding protein-1 is an antigonadotropin: evidence that optimal follicle-stimulating hormone action in ovarian granulosa cells is contingent upon amplification by endogenously-derived IGFs

artículo científico publicado en 1993

Insulin-like growth factor (IGF) parameters and tools for efficacy: the IGF-I generation test in children

artículo científico publicado en 2004

Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition ⬇️

artículo científico publicado el 15 de julio de 1993

Insulin-like growth factor I improves height in growth hormone insensitivity: two years' results

artículo científico publicado en 1995

Insulin-like growth factor I/somatomedin-C (IGF-I/SM-C) and glucocorticoids synergistically regulate mitosis in competent human fibroblasts ⬇️

artículo científico publicado el 1 de agosto de 1983

Insulin-like growth factor II binding and action in human fetal fibroblasts

artículo científico publicado en 1987

Insulin-like growth factor axis abnormalities in prostatic stromal cells from patients with benign prostatic hyperplasia

artículo científico publicado en 1994

Insulin-like growth factor binding protein (IGFBP)-3 levels in conditioned media of Hs578T human breast cancer cells are post-transcriptionally regulated

artículo científico publicado el 1 de marzo de 1993

Insulin-like growth factor binding protein 3 mediates retinoic acid- and transforming growth factor beta2-induced growth inhibition in human breast cancer cells.

artículo científico publicado en 1996

Insulin-like growth factor binding protein expression in the hypothyroid rat is age dependent

artículo científico publicado el 1 de septiembre de 1992

Insulin-like growth factor binding protein production in human follicular thyroid carcinoma cells

artículo científico publicado en 1995

Insulin-like growth factor binding protein-3 and-5 are regulated by transforming growth factor-β and retinoic acid in the human prostate adenocarcinoma cell line PC-3 ⬇️

artículo científico publicado el 1 de junio de 1997

Insulin-like growth factor binding protein-3 generation as a measure of GH sensitivity

artículo científico publicado en 2002

Insulin-like growth factor binding protein-3 protease activity in the urine of children with chronic renal failure ⬇️

artículo científico publicado el 1 de agosto de 1993

Insulin-like growth factor binding protein-4 accumulation is negatively correlated with growth rate in TM-3 cells

artículo científico publicado en 1998

Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) is a potential tumor suppressor protein for prostate cancer

artículo científico publicado en 1999

Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1/MAC25) is linked to endothelial-dependent vasodilation in high-ferritin type 2 diabetes

artículo científico publicado en 2007

Insulin-like growth factor binding proteins (IGFBPs) and IGFBP-related protein 1-levels in cerebrospinal fluid of children with acute lymphoblastic leukemia

artículo científico publicado en 1999

Insulin-like growth factor binding proteins from cultured human fibroblasts. Characterization and hormonal regulation

artículo científico publicado en 1989

Insulin-like growth factor binding proteins in human breast cancer cells: relationship to hIGFBP-2 and hIGFBP-3.

artículo científico publicado en 1990

Insulin-like growth factor binding proteins in human endometrium: steroid-dependent messenger ribonucleic acid expression and protein synthesis

artículo científico publicado en 1991

Insulin-like growth factor binding proteins in sera of pregnant nonhuman primates ⬇️

artículo científico publicado el 1 de abril de 1993

Insulin-like growth factor binding proteins: a proposed superfamily

artículo científico publicado en 1999

Insulin-like growth factor receptors

artículo científico publicado en 1991

Insulin-like growth factor receptors and binding protein in rat neuroblastoma cells

artículo científico publicado en 1989

Insulin-like growth factor-I (IGF-I) and IGF-II hormonal action in cultured rat granulosa cells: mediation via type I but not type II IGF receptors

scientific article published on 01 January 1990

Insulin-like growth factor-I in growth and metabolism.

artículo científico publicado en 2010

Insulin-like growth factor-I is internalized after binding to the type I insulin-like growth factor receptor

artículo científico publicado en 1989

Insulin-like growth factor-binding protein-2 concentrations in cerebrospinal fluid and serum of children with malignant solid tumors or acute leukemia

artículo científico publicado en 1994

Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics

artículo científico publicado en 1996

Insulin-like growth factors (IGFs) block FSH-induced proteolysis of IGF-binding protein-5 (BP-5) in cultured rat granulosa cells ⬇️

artículo científico publicado el 1 de julio de 1993

Insulin-like growth factors (IGFs) stimulate and dexamethasone inhibits IGF binding protein (BP)-5 expression in a mouse pituitary cell line.

artículo científico publicado en 1993

Insulin-like growth factors I and II and their binding proteins in human milk: effect of heat treatment on IGF and IGF binding protein stability.

artículo científico publicado en 1991

Insulin-like growth factors I and II and their binding proteins in rat milk

artículo científico publicado en 1991

Insulin-like growth factors I and II in evaluation of growth retardation

artículo científico publicado en 1986

Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth.

artículo científico publicado en 1995

Insulin-like growth factors are mitogenic for human keratinocytes and a squamous cell carcinoma

artículo científico publicado en 1991

Insulinlike Growth Factor-Binding Proteins

artículo científico publicado el 1 de enero de 1990

Insulin‐like growth factor binding proteins and their regulation ⬇️

artículo científico publicado el 1 de abril de 1994

Interaction of IGF-binding protein-related protein 1 with a novel protein, neuroendocrine differentiation factor, results in neuroendocrine differentiation of prostate cancer cells

artículo científico publicado en 2001

Interferon-gamma-induced dephosphorylation of STAT3 and apoptosis are dependent on the mTOR pathway

artículo científico publicado en 2006

Intrauterine and postnatal growth failure with normal GH/IGF1 axis and insulin-resistant diabetes in a consanguineous kinship ⬇️

artículo científico publicado el 14 de diciembre de 2011

Investigation into the potential physiological sources of rat milk IGF-I and IGF-binding proteins

artículo científico publicado en 1995

Is growth hormone deficiency a viable diagnosis?

artículo científico publicado en 1997

Is there a medical need to explore the clinical use of insulin-like growth factor I?

artículo científico publicado en 2001

Is there heterozygote expression of growth hormone receptor deficiency?

scientific article published on 01 April 1994

Leptin concentrations in GH deficiency: the effect of GH insensitivity

artículo científico publicado en 2002

Levels of Insulin-like Growth Factors I and II in Human Cord Blood* ⬇️

artículo científico publicado el 1 de septiembre de 1983

Linear growth response to exogenous growth hormone in Prader-Willi syndrome.

artículo científico publicado en 1987

Localization and structural characterization of insulin-like growth factor receptors in mammalian retina

artículo científico publicado en 1989

Long-Acting C-Terminal Peptide-Modified hGH (MOD-4023): Results of a Safety and Dose-Finding Study in GHD Children

artículo científico publicado en 2017

Long-Term Surveillance of Growth Hormone Therapy ⬇️

artículo científico publicado el 15 de diciembre de 2011

Long-term effects of insulin-like growth factor (IGF)-I treatment on serum IGFs and IGF binding proteins in adolescent patients with growth hormone receptor deficiency

artículo científico publicado en 1995

Long-term treatment of growth hormone insensitivity syndrome with IGF-I. Results of the European Multicentre Study. The Working Group on Growth Hormone Insensitivity Syndromes

artículo científico publicado en 1999

Maternal Insulin-Like Growth Factor-Binding Protein Messenger Ribonucleic Acid during Rat Pregnancy* ⬇️

artículo científico publicado el 1 de diciembre de 1991

Maternal hypoxia as a model for intrauterine growth retardation: effects on insulin-like growth factors and their binding proteins

artículo científico publicado en 1994

Measurement and characterization of insulin-like growth factor binding protein-3 in human biological fluids: discrepancies between radioimmunoassay and ligand blotting ⬇️

artículo científico publicado el 1 de diciembre de 1992

Mechanisms of thyroid hormone action on the insulin-like growth factor system: all thyroid hormone effects are not growth hormone mediated ⬇️

artículo científico publicado el 1 de febrero de 1993

Meeting Report: The 2015-USFQ Biennial Meeting on Growth Hormone Research

Meeting Reports: The 2017-USFQ Biennial Meeting on Growth Hormone and IGF1 Research

scientific article published on 01 December 2017

Methionyl human growth hormone and oxandrolone in Turner syndrome: preliminary results of a prospective randomized trial

artículo científico publicado en 1986

Modulation of Homologous Receptor Concentratons: A Sensitive Radioassay for Human Growth Hormone in Acromegalic, Newborn, and Stimulated Plasma* ⬇️

artículo científico publicado el 1 de enero de 1980

Molecular mechanisms of IGF-I deficiency

artículo científico publicado en 2006

Monitoring rhGH Safety: rhGH Registries, SAGhE and Future Needs

artículo científico publicado en 2018

Mortality in Children Receiving Growth Hormone Treatment for Growth Disorders: Data from the GeNeSIS Observational Program

artículo científico publicado en 2017

Mutation creating a new splice site in the growth hormone receptor genes of 37 Ecuadorean patients with Laron syndrome ⬇️

artículo científico publicado el 1 de enero de 1992

Mutation of three critical amino acids of the N-terminal domain of IGF-binding protein-3 essential for high affinity IGF binding

artículo científico publicado en 2001

Mutations in pregnancy-associated plasma protein A2 cause short stature due to low IGF-I availability

artículo científico publicado en 2016

Natural history of growth hormone receptor deficiency.

artículo científico publicado en 1999

New concepts in insulin-like growth factor receptor physiology.

artículo científico publicado en 1993

New molecular mechanisms of GH resistance

artículo científico publicado en 2004

Nomenclature of the insulin-like growth factor-binding protein superfamily

artículo científico publicado en 2001

Non-conventional growth hormone therapy in Turner syndrome: the United States experience

artículo científico publicado en 1990

Non-receptor mediated, post-transcriptional regulation of insulin-like growth factor binding protein (IGFBP)-3 in Hs578T human breast cancer cells ⬇️

artículo científico publicado el 1 de diciembre de 1992

Nonclassical GH Insensitivity: Characterization of Mild Abnormalities of GH Action

scientific article published on 01 April 2019

Normal Somatomedin and Somatomedin Receptors in Achondroplastic Dwarfism ⬇️

artículo científico publicado el 1 de febrero de 1980

Normal somatomedin-C/insulin-like growth factor I binding and action in cultured human fibroblasts from Turner syndrome ⬇️

artículo científico publicado el 1 de diciembre de 1983

Not all insulin-like growth factor-binding proteins (IGFBPs) are detectable by western ligand blotting: case studies of PC12 pheochromocytoma and rat anterior pituitary IGFBPs and proteolyzed IGFBP-3.

artículo científico publicado en 1992

Novel Dominant-Negative GH Receptor Mutations Expands the Spectrum of GHI and IGF-I Deficiency.

artículo científico publicado en 2017

Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein

artículo científico publicado en 2012

Novel spinal dysplasia in two generations

artículo científico publicado en 1995

Ontogeny of insulin-like growth factor-binding protein-1, -2, and -3: quantitative measurements by radioimmunoassay in human fetal serum

scientific article published on 01 October 1994

Ontogeny of pituitary regulation of growth in the developing rat: comparison of effects of hypophysectomy and hormone replacement on somatic and organ growth, serum insulin-like growth factor-I (IGF-I) and IGF-II levels, and IGF-binding protein leve ⬇️

artículo científico publicado el 1 de febrero de 1991

Ontogeny of serum insulin-like growth factor binding proteins in the rat.

artículo científico publicado en 1989

Personalized approach to growth hormone treatment: clinical use of growth prediction models.

artículo científico publicado en 2013

Pharmacokinetic and Pharmacodynamic Modeling of MOD-4023, a Long-Acting Human Growth Hormone, in Growth Hormone Deficiency Children

artículo científico publicado en 2017

Pharmacokinetics of recombinant human insulin-like growth factor I given subcutaneously to healthy volunteers and to patients with growth hormone receptor deficiency

artículo científico publicado en 1993

Phenotype: Genotype Relationships in Growth Hormone Insensitivity Syndrome1 ⬇️

artículo científico publicado el 1 de noviembre de 1997

Pituitary Control of Growth in the Neonatal Rat: Effects of Neonatal Hypophysectomy on Somatic and Organ Growth, Serum Insulin-Like Growth Factors (IGF)-I and -II Levels, and Expression of IGF Binding Proteins* ⬇️

artículo científico publicado el 1 de octubre de 1990

Plasma Somatomedin-Binding Proteins in Hypopituitarism: Changes during Growth Hormone Therapy* ⬇️

artículo científico publicado el 1 de julio de 1981

Plasma somatomedin-C levels in psoriasis

scientific article published on 01 January 1987

Pregnancy in growth hormone-deficient rats: assessment of insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs) and IGFBP protease activity ⬇️

artículo científico publicado el 1 de marzo de 1993

Presence of insulinlike growth factor receptors and lack of insulin receptors on fetal bovine smooth muscle cells

artículo científico publicado en 1988

Primary growth hormone (GH) insensitivity and insulin-like growth factor deficiency caused by novel compound heterozygous mutations of the GH receptor gene: genetic and functional studies of simple and compound heterozygous states

scientific article published on 03 April 2007

Production of monoclonal antibodies to the rat insulin-like growth factor II (IGF-II) receptor

scientific article published on 01 July 1987

Prospective clinical trial of human growth hormone in short children without growth hormone deficiency ⬇️

artículo científico publicado el 1 de febrero de 1984

Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma

artículo científico publicado en 1992

Proteolysis of IGFBP-3 may be a common regulatory mechanism of IGF action in vivo

artículo científico publicado el 1 de marzo de 1993

Psychosocial correlates of short stature and delayed puberty

artículo científico publicado en 1987

Purification of the insulin-like growth factor II (IGF-II) receptor from an IGF-II-producing cell line, and generation of an antibody which both immunoprecipitates and blocks the type 2 IGF receptor

artículo científico publicado en 1986

Recombinant DNA-derived methionyl human growth hormone is similar in membrane binding properties to human pituitary growth hormone ⬇️

artículo científico publicado el 14 de mayo de 1982

Recommendations for Diagnosis, Treatment, and Management of Individuals with Turner Syndrome

article

Recommendations for nomenclature of the insulin-like growth factor binding protein (IGFBP) superfamily

artículo científico publicado en 1998

Recommendations for nomenclature of the insulin-like growth factor binding protein superfamily

artículo científico publicado en 1998

Recommendations for nomenclature of the insulin-like growth factor binding protein superfamily

artículo científico publicado en 1998

Regulation of Serum Insulin-Like Growth Factors and Their Binding Proteins in Ecuadorean Patients with Growth Hormone Receptor Dysfunction (Growth Hormone Insensitivity) ⬇️

artículo científico publicado el 1 de enero de 1991

Regulation of extragonadal insulin-like growth factor-binding protein-3 by testosterone in oophorectomized women

artículo científico publicado en 1994

Regulation of growth hormone release from cultured human pituitary adenomas by somatomedins and insulin

artículo científico publicado en 1985

Regulation of insulin-like growth factor-binding protein expression by thyroid hormone in rat GH3 pituitary tumor cells

artículo científico publicado en 1992

Reproducibility in Patterns of IGF Generation with Special Reference to Idiopathic Short Stature ⬇️

artículo científico publicado el 1 de enero de 2003

Results from the first 2 years of a clinical trial with recombinant DNA-derived human growth hormone (somatrem) in Turner's syndrome

scientific article published on 01 January 1987

STAT5B mutations in heterozygous state have negative impact on height: another clue in human stature heritability

artículo científico publicado en 2015

STAT5b Deficiency: An Unsuspected Cause of Growth Failure, Immunodeficiency, and Severe Pulmonary Disease ⬇️

artículo científico publicado el 17 de marzo de 2011

STAT5b deficiency: Lessons from STAT5b gene mutations ⬇️

artículo científico publicado el 1 de febrero de 2011

Safety Outcomes During Pediatric GH Therapy: Final Results From the Prospective GeNeSIS Observational Program

scientific article published on 01 February 2019

Safety of recombinant deoxyribonucleic acid-derived growth hormone: The National Cooperative Growth Study experience

artículo científico publicado en 1996

Screening a large pediatric cohort with GH deficiency for mutations in genes regulating pituitary development and GH secretion: Frequencies, phenotypes and growth outcomes

artículo científico publicado en 2018

Sensitivity to growth hormone-the perspective. Round table discussion

artículo científico publicado en 2001

Serum concentrations of insulin-like growth factor (IGF)-1, IGF-2 and unsaturated somatomedin carrier proteins in children with chronic renal failure

scientific article published on 01 October 1987

Serum free thyroxine values in term, premature, and sick infants

artículo científico publicado en 1982

Serum ghrelin levels are inversely correlated with body mass index, age, and insulin concentrations in normal children and are markedly increased in Prader-Willi syndrome

artículo científico publicado en 2003

Serum glucocorticoids have persistent and controlling effects on insulinlike growth factor I action under serum-free assay conditions in cultured human fibroblasts

artículo científico publicado en 1989

Serum insulin-like growth factors I and II concentrations and growth hormone and insulin responses to arginine infusion in children with protein-energy malnutrition before and after nutritional rehabilitation.

artículo científico publicado en 1986

Serum levels of insulin-like growth factor binding proteins in Ecuadorean children with growth hormone insensitivity

scientific article published on 01 February 1999

Serum profiles of insulin‐like growth factors and their binding proteins in adults with growth hormone receptor deficiency treated with insulin like growth factor I ⬇️

artículo científico publicado el 1 de marzo de 1993

Serum somatomedin levels in adults with chronic renal failure: the importance of measuring insulin-like growth factor I (IGF-I) and IGF-II in acid-chromatographed uremic serum

artículo científico publicado en 1986

Severe Growth Deficiency is Associated with STAT5b Mutations that Disrupt Protein Folding and Activity ⬇️

artículo científico publicado el 16 de noviembre de 2012

Severe growth hormone insensitivity resulting from total absence of signal transducer and activator of transcription 5b.

artículo científico publicado en 2005

Severe short stature caused by novel compound heterozygous mutations of the insulin-like growth factor 1 receptor (IGF1R)

scientific article published on 30 November 2011

Sex chromosome fragment in a phenotypically normal female. Significance of occult Y-related material

artículo científico publicado en 1986

Sexual and somatic determinants of the human Y chromosome: studies in a 46,XYp- phenotypic female ⬇️

artículo científico publicado el 1 de julio de 1979

Short stature in partially corrected X-linked severe combined immunodeficiency--suboptimal response to growth hormone

artículo científico publicado en 2008

Should we treat children with idiopathic short stature?

artículo científico publicado en 1999

Simultaneous inhibition of insulin and somatomedin-C binding to cultured IM-9 lymphocytes by naturally occurring antireceptor antibodies

scientific article published on 01 November 1981

Six-year results of a randomized, prospective trial of human growth hormone and oxandrolone in Turner syndrome ⬇️

artículo científico publicado el 1 de julio de 1992

Somatic and intellectual development in a patient with 47,XX,psu dic(X)(p11.2) chromosome constitution

artículo científico publicado en 1989

Somatomedin C-binding and action in fibroblasts from aged and progeric subjects

artículo científico publicado en 1985

Somatomedin C/insulin-like growth factor I binding and action in human fibroblasts aged in culture: impaired synergism with dexamethasone

artículo científico publicado en 1987

Somatomedin Peptide Distribution and Somatomedin-Binding Protein Content in Cord Plasma: Comparison to Normal and Hypopituitary Plasma* ⬇️

artículo científico publicado el 1 de febrero de 1982

Somatomedin-C in accelerated growth of children with precocious puberty

scientific article published on 01 July 1985

Somatomedins in Adolescence: A Cross-Sectional Study of the Effect of Puberty on Plasma Insulin-Like Growth Factor I and II Levels* ⬇️

artículo científico publicado el 1 de agosto de 1983

Somatomedins in pregnancy: a cross-sectional study of insulin-like growth factors I and II and somatomedin peptide content in normal human pregnancies

artículo científico publicado en 1982

Structural and immunohistochemical characterization of insulin-like growth factor I and II receptors in the murine central nervous system

artículo científico publicado en 1988

Structural and immunological characterization of insulin-like growth factor II binding to IM-9 cells

artículo científico publicado en 1986

Structural and immunological comparison of insulin-like growth factor binding proteins of cerebrospinal and amniotic fluids

artículo científico publicado en 1989

Structural characterization and immunohistochemical localization of receptors for insulin-like growth factor II in the rat pituitary gland

artículo científico publicado en 1989

Subcutaneous versus intramuscular growth hormone therapy: growth and acute somatomedin response

artículo científico publicado en 1985

Suppression of the growth hormone (GH) response to clonidine and GH-releasing hormone by exogenous GH

artículo científico publicado en 1986

Synthesis and characterization of IGF-II analogs: applications in the evaluation of IGF receptor function and IGF-independent actions of IGFBPs.

artículo científico publicado en 1993

Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7. Recombinant human mac25 protein specifically binds IGF-I and -II

artículo científico publicado en 1996

Synthesis of IGFBP-3 fragments in a baculovirus system and characterization of monoclonal anti-IGFBP-3 antibodies

artículo científico publicado en 1997

Testicular tumors with Peutz-Jeghers syndrome

artículo científico publicado en 1986

The E180splice mutation in theGHRgene causing Laron syndrome: Witness of a Sephardic Jewish exodus from the Iberian Peninsula to the New World?

artículo científico publicado en 2014

The Effects of Thyroid Hormone on Insulin-Like Growth Factor (IGF) and IGF-Binding Protein (IGFBP) Expression in the Neonatal Rat: Prolonged High Expression of IGFBP-2 in Methimazole- Induced Congenital Hypothyroidism* ⬇️

artículo científico publicado el 1 de noviembre de 1991

The Growth Hormone Receptor (GHR)c.899dupCMutation Functions as a Dominant Negative: Insights into the Pathophysiology of IntracellularGHRDefects ⬇️

artículo científico publicado el 7 de septiembre de 2011

The IGF axis in the prostate

artículo científico publicado en 1994

The IGF-I Generation Test Revisited: A Marker of GH Sensitivity ⬇️

artículo científico publicado el 1 de noviembre de 2001

The Mouse Intraovarian Insulin-Like Growth Factor I System: Departures from the Rat Paradigm* ⬇️

artículo científico publicado el 1 de septiembre de 1997

The composition and distribution of insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) in the serum of growth hormone receptor-deficient patients: effects of IGF-I therapy on IGFBP-3.

artículo científico publicado en 1993

The continuum of growth hormone-IGF-I axis defects causing short stature: diagnostic and therapeutic challenges

scientific article published on 29 December 2009

The effect of GH therapy on the immunoreactive forms and distribution of IGFBP-3, IGF-I, the acid-labile subunit, and growth rate in GH-deficient children ⬇️

artículo científico publicado el 1 de diciembre de 1997

The effects of short-term administration of two low doses versus the standard GH replacement dose on insulin sensitivity and fasting glucose levels in young healthy adults

artículo científico publicado en 2002

The future of growth-promoting therapy

artículo científico publicado en 2015

The future of research into growth hormone responsiveness

artículo científico publicado en 2009

The growth hormone (GH)-releasing hormone (GHRH)-GH-somatomedin axis: evidence for rapid inhibition of GHRH-elicited GH release by insulin-like growth factors I and II.

artículo científico publicado en 1987

The growth hormone cascade and its role in mammalian growth

scientific article published on 29 April 2009

The insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor mediates IGF-II-induced motility in human rhabdomyosarcoma cells ⬇️

artículo científico publicado el 5 de mayo de 1992

The insulin-like growth factor binding protein superfamily: new perspectives

artículo científico publicado en 1999

The insulin-like growth factor system in human peritoneal fluid: its effects on endometrial stromal cells and its potential relevance to endometriosis

artículo científico publicado en 1994

The insulin-like growth factor system in the prostate.

artículo científico publicado en 1995

The insulin-like growth factor-binding protein (IGFBP) superfamily

artículo científico publicado en 1999

The insulin-like growth factor-binding protein superfamily

artículo científico publicado en 2000

The little women of Loja--growth hormone-receptor deficiency in an inbred population of southern Ecuador

artículo científico publicado en 1990

The molecular basis of idiopathic short stature

artículo científico publicado en 2005

The ovarian expression of the antigonadotropic insulin-like growth factor binding protein-2 is theca-interstitial cell-selective: evidence for hormonal regulation ⬇️

artículo científico publicado el 1 de octubre de 1991

The role of insulin-like growth factors in prostate biology.

artículo científico publicado en 1996

The roles of insulin sensitivity, insulin-like growth factor I (IGF-I), and IGF-binding protein-1 and -3 in the hyperandrogenism of African-American and Caribbean Hispanic girls with premature adrenarche

artículo científico publicado en 1999

The transition from adolescence to adult life: physiology of the 'transition' phase and its evolutionary basis

artículo científico publicado en 2003

The utility of the IGF-I generation test in children with chronic kidney disease

artículo científico publicado en 2013

Three novel IGFALS gene mutations resulting in total ALS and severe circulating IGF-I/IGFBP-3 deficiency in children of different ethnic origins

artículo científico publicado en 2009

Three-year results of a randomized prospective trial of methionyl human growth hormone and oxandrolone in Turner syndrome ⬇️

artículo científico publicado el 1 de agosto de 1988

Total absence of functional acid labile subunit, resulting in severe insulin-like growth factor deficiency and moderate growth failure.

artículo científico publicado en 2006

Toward a molecular basis for idiopathic short stature

scientific article published on 01 March 2004

Transcriptional and post-translational regulation of insulin-like growth factor-binding protein-5 in rat articular chondrocytes

artículo científico publicado en 1996

Transcriptional and posttranscriptional regulation of intraovarian insulin-like growth factor-binding proteins by interleukin-1beta (IL-1beta): evidence for IL-1beta as an antiatretic principal

scientific article published on 01 August 1999

Transcriptional regulation of insulin-like growth factor-I by interferon-gamma requires STAT-5b

artículo científico publicado en 2003

Transfection of the human IGFBP-3 gene into Balb/c fibroblasts: a model for the cellular functions of IGFBPs

artículo científico publicado el 1 de marzo de 1993

Transfection of the human insulin-like growth factor binding protein-3 gene into Balb/c fibroblasts inhibits cellular growth ⬇️

artículo científico publicado el 1 de marzo de 1993

Transforming growth factor-beta-induced cell growth inhibition in human breast cancer cells is mediated through insulin-like growth factor-binding protein-3 action.

artículo científico publicado en 1995

Transition from pediatric to adult care for growth hormone deficiency

scientific article published on 01 May 2003

Transitioning patients with childhood-onset growth hormone deficiency to treatment in adulthood.

artículo científico publicado en 2002

Transplantation of insulin-like growth factor-II-secreting tumors into nude rodents

scientific article published on 01 May 1987

Treatment With Recombinant Human Insulin-Like Growth Factor-1 Improves Growth in Patients With PAPP-A2 Deficiency

artículo científico publicado en 2016

Treatment of Turner's syndrome with recombinant human growth hormone (somatrem).

artículo científico publicado en 1988

Treatment of short stature and delayed adolescence

artículo científico publicado en 1987

Triiodothyronine regulates insulin-like growth factor-I binding to cultured rat pituitary cells

artículo científico publicado en 1989

Triple A syndrome in a patient with genetic growth hormone insensitivity: phenotypic effects of two genetic disorders.

artículo científico publicado en 2012

Turner syndrome adolescents receiving growth hormone are not osteopenic

artículo científico publicado en 1993

Two-year treatment of growth hormone (GH) receptor deficiency with recombinant insulin-like growth factor I in 22 children: comparison of two dosage levels and to GH-treated GH deficiency

scientific article published on 01 February 1997

Up-regulation of IGF-I receptors on IM-9 cells by IGF-II peptides.

artículo científico publicado en 1989

Urinary insulin-like growth factors (IGF) and IGF-binding proteins in normal subjects, growth hormone deficiency, and renal disease ⬇️

artículo científico publicado el 1 de junio de 1993

Usefulness of different biochemical markers of the insulin-like growth factor (IGF) family in diagnosing growth hormone excess and deficiency in adults

artículo científico publicado en 2001

Valid measurements of total IGF concentrations in biological fluids. Recommendations from the 3rd International Symposium on Insulin-like Growth Factors

artículo científico publicado en 1994

Variable degree of growth hormone (GH) and insulin-like growth factor (IGF) sensitivity in children with idiopathic short stature compared with GH-deficient patients: evidence from an IGF-based dosing study of short children

artículo científico publicado en 2010

[Insulin growth factor-I-based dosing of growth hormone therapy in children: a randomized, controlled study]

scientific article published on 15 April 2009

[Leu27] insulin-like growth factor II is highly selective for the type-II IGF receptor in binding, cross-linking and thymidine incorporation experiments

artículo científico publicado en 1991

40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004 ⬇️

artículo

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