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A New Role of Mister (MR) T in Hypertension: Mineralocorticoid Receptor, Immune System, and Hypertension.

artículo científico publicado en 2017

A new paradigm of sodium regulation in inflammation and hypertension

artículo científico publicado en 2017

A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth

artículo científico publicado el 20 de octubre de 2011

CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive Stimuli

artículo científico publicado en 2016

Cell death induced by the Jak2 inhibitor, G6, correlates with cleavage of vimentin filaments.

artículo científico publicado en 2011

DC isoketal-modified proteins activate T cells and promote hypertension.

artículo científico publicado en 2014

Dendritic Cell A20: Targeting Hypertension in Autoimmunity

artículo científico publicado en 2019

Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension

artículo científico publicado en 2017

Dendritic cells and isolevuglandins in immunity, inflammation, and hypertension

artículo científico publicado en 2016

Do high-salt microenvironments drive hypertensive inflammation?

artículo científico publicado en 2016

Elevated Eosinophils as a Feature of Inflammation Associated With Hypertension in Virally Suppressed People Living With HIV

scientific article published on 17 February 2020

Elevated levels of mast cells are involved in pruritus associated with polycythemia vera in JAK2V617F transgenic mice

artículo científico publicado en 2014

From Rags to Riches: Moving Beyond RAG1 in Studies of Hypertension

artículo científico publicado en 2020

HIV, immune activation and salt-sensitive hypertension (HISH): a research proposal

scientific article published on 16 July 2019

High CD8 T-Cell Receptor Clonality and Altered CDR3 Properties Are Associated With Elevated Isolevuglandins in Adipose Tissue During Diet-Induced Obesity

scientific article published on 04 September 2018

High Salt Activates CD11c+ Antigen-Presenting Cells via SGK (Serum Glucocorticoid Kinase) 1 to Promote Renal Inflammation and Salt-Sensitive Hypertension

scientific article published on 08 July 2019

High dietary salt-induced dendritic cell activation underlies microbial dysbiosis-associated hypertension

scientific article published on 04 June 2019

Highly Reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension

artículo científico publicado en 2020

Identification of a novel inhibitor of JAK2 tyrosine kinase by structure-based virtual screening

artículo científico publicado en 2009

Identification of tyrosine 972 as a novel site of Jak2 tyrosine kinase phosphorylation and its role in Jak2 activation

artículo científico publicado en 2008

Immune activation caused by vascular oxidation promotes fibrosis and hypertension

artículo científico publicado en 2015

Immune activation caused by vascular oxidation promotes fibrosis and hypertension.

artículo científico publicado en 2016

Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase.

artículo científico publicado en 2013

Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells

artículo científico publicado en 2019

Isolevuglandins as mediators of disease and the development of dicarbonyl scavengers as pharmaceutical interventions

scientific article published on 16 October 2019

Jak2 Tyrosine Kinase: A Potential Therapeutic Target for AT1 Receptor Mediated Cardiovascular Disease.

artículo científico publicado en 2010

Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation

artículo científico publicado en 2015

Mechanisms of Isolevuglandin-protein Adduct Formation in Inflammation and Hypertension

artículo científico publicado en 2018

Neuregulin-1β induces proliferation, survival and paracrine signaling in normal human cardiac ventricular fibroblasts

artículo científico publicado en 2017

Oligoclonal CD8+ T cells play a critical role in the development of hypertension

artículo científico publicado en 2014

Patho-immune Mechanisms of Hypertension in HIV: a Systematic and Thematic Review

scientific article published on 04 June 2019

Renal Denervation Prevents Immune Cell Activation and Renal Inflammation in Angiotensin II-Induced Hypertension

artículo científico publicado en 2015

Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice

artículo científico publicado en 2015

The Jak2 inhibitor, G6, alleviates Jak2-V617F-mediated myeloproliferative neoplasia by providing significant therapeutic efficacy to the bone marrow

artículo científico publicado en 2011

The Stilbenoid Tyrosine Kinase Inhibitor, G6, Suppresses Jak2-V617F-mediated Human Pathological Cell Growth in Vitro and in Vivo

artículo científico publicado el 2 de diciembre de 2010

The small molecule inhibitor G6 significantly reduces bone marrow fibrosis and the mutant burden in a mouse model of Jak2-mediated myelofibrosis.

artículo científico publicado en 2012

Vascular smooth muscle Jak2 deletion prevents angiotensin II-mediated neointima formation following injury in mice.

artículo científico publicado en 2011

Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species

artículo científico publicado el 24 de febrero de 2011