Lista de obras -

A sweet link between TGFbeta and vascular disease?

artículo científico publicado en 2006

BMP-9 balances endothelial cell fate

artículo científico publicado en 2013

Cancer: dangerous liaisons

artículo científico publicado en 2004

Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition

scientific article published on 26 February 2019

Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice ⬇️

artículo científico publicado el 1 de junio de 1995

Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β.

artículo científico publicado en 2012

Differentiation plasticity regulated by TGF-beta family proteins in development and disease

artículo científico publicado en 2007

Elevated cutaneous Smad activation associates with enhanced skin tumor susceptibility in organ transplant recipients

artículo científico publicado en 2009

Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo ⬇️

artículo científico publicado el 1 de enero de 1991

Enhanced TGF-β Signaling Contributes to the Insulin-Induced Angiogenic Responses of Endothelial Cells

article

Epistatic interactions between Tgfb1 and genetic loci, Tgfbm2 and Tgfbm3, determine susceptibility to an asthmatic stimulus

artículo científico publicado en 2012

Epistatic interactions between modifier genes confer strain-specific redundancy for Tgfb1 in developmental angiogenesis

artículo científico publicado en 2005

Epithelial carcinogenesis in the mouse: correlating the genetics and the biology ⬇️

artículo científico publicado el 29 de junio de 1998

Erratum: Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia

artículo científico publicado en 2012

Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain

artículo científico publicado en 2014

From prevention to cure, repurposing anti-viral vaccines for cancer immunotherapy

scientific article published on 01 December 2018

Functional loss of tumour suppressor genes in multistage chemical carcinogenesis

artículo científico publicado el 1 de enero de 1991

Genetic modifiers interact with maternal determinants in vascular development of Tgfb1(-/-) mice

scientific article published on 01 July 2003

Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.

artículo científico publicado en 2014

Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility.

artículo científico publicado en 2006

Genetic variation in the functional ENG allele inherited from the non-affected parent associates with presence of pulmonary arteriovenous malformation in hereditary hemorrhagic telangiectasia 1 (HHT1) and may influence expression of PTPN14

artículo científico publicado en 2015

Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy

artículo científico publicado en 2021

Large- and small-molecule inhibitors of transforming growth factor-beta signaling.

artículo científico publicado en 2006

Latent transforming growth factor-beta activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation

artículo científico publicado en 2002

Matters of context guide future research in TGFβ superfamily signaling

artículo científico publicado en 2015

Metastasis is driven by sequential elevation of H-ras and Smad2 levels.

artículo científico publicado en 2002

Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia

artículo científico publicado en 2012

Mouse strain-dependent heterogeneity of resting limbal vasculature

artículo científico publicado en 2004

Multiple self-healing squamous epithelioma (MSSE): rare variants in an adjacent region of chromosome 9q22.3 to known TGFBR1 mutations suggest a digenic or multilocus etiology

artículo científico publicado en 2013

Mutations of TGFbeta signaling molecules in human disease

artículo científico publicado en 2006

Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term TβRI/II kinase inhibition with LY2109761.

artículo científico publicado en 2011

RNA and protein localisations of TGFβ2 in the early mouse embryo suggest an involvement in cardiac development ⬇️

artículo científico publicado el 1 de febrero de 1993

ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation

artículo científico publicado en 2015

Smad3-mediated recruitment of the methyltransferase SETDB1/ESET controls Snail1 expression and epithelial-mesenchymal transition.

artículo científico publicado en 2017

TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis ⬇️

artículo científico publicado el 1 de abril de 1990

TGF beta inhibition for cancer therapy

artículo científico publicado en 2006

TGF beta signaling in health and disease

artículo científico publicado en 2004

TGF-beta antagonists: why suppress a tumor suppressor?

artículo científico publicado en 2002

TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion

artículo científico publicado en 2012

TGFbeta inhibition of yolk-sac-like differentiation of human embryonic stem-cell-derived embryoid bodies illustrates differences between early mouse and human development

artículo científico publicado en 2006

TGFβ biology in cancer progression and immunotherapy

artículo científico publicado en 2020

TGFβ1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo.

artículo científico publicado en 2011

Taking thalidomide out of rehab

artículo científico publicado en 2010

Targeting TGF-β Signaling for Therapeutic Gain

artículo científico publicado en 2017

Targeting the TGFβ signalling pathway in disease

artículo científico publicado en 2012

The Role of TGF? in Mouse Development ⬇️

artículo científico publicado el 1 de enero de 1990

The complexities of TGF-β action during mammary and squamous cell carcinogenesis

artículo científico publicado en 2011

The paradoxical TGF-β vasculopathies ⬇️

artículo científico publicado el 27 de julio de 2012

The type I TGF-beta receptor is covalently modified and regulated by sumoylation

artículo científico publicado en 2008

Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion ⬇️

artículo científico publicado el 1 de mayo de 1998

Transforming growth factor-beta in breast cancer: too much, too late

scientific article published on 26 February 2009

Transforming growth factor-beta receptor inhibition enhances adenoviral infectability of carcinoma cells via up-regulation of Coxsackie and Adenovirus Receptor in conjunction with reversal of epithelial-mesenchymal transition.

artículo científico publicado en 2006

Transforming growth factor-beta1 mediates cellular response to DNA damage in situ.

artículo científico publicado en 2002

α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas

scientific article published on 04 March 2019

Lista de obras de

A sweet link between TGFbeta and vascular disease?

BMP-9 balances endothelial cell fate

Cancer: dangerous liaisons

Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition

Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice ⬇️

Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β.

Differentiation plasticity regulated by TGF-beta family proteins in development and disease

Elevated cutaneous Smad activation associates with enhanced skin tumor susceptibility in organ transplant recipients

Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo ⬇️

Enhanced TGF-β Signaling Contributes to the Insulin-Induced Angiogenic Responses of Endothelial Cells

Epistatic interactions between Tgfb1 and genetic loci, Tgfbm2 and Tgfbm3, determine susceptibility to an asthmatic stimulus

Epistatic interactions between modifier genes confer strain-specific redundancy for Tgfb1 in developmental angiogenesis

Epithelial carcinogenesis in the mouse: correlating the genetics and the biology ⬇️

Erratum: Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia

Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain

From prevention to cure, repurposing anti-viral vaccines for cancer immunotherapy

Functional loss of tumour suppressor genes in multistage chemical carcinogenesis

Genetic modifiers interact with maternal determinants in vascular development of Tgfb1(-/-) mice

Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.

Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility.

Genetic variation in the functional ENG allele inherited from the non-affected parent associates with presence of pulmonary arteriovenous malformation in hereditary hemorrhagic telangiectasia 1 (HHT1) and may influence expression of PTPN14

Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy

Large- and small-molecule inhibitors of transforming growth factor-beta signaling.

Latent transforming growth factor-beta activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation

Matters of context guide future research in TGFβ superfamily signaling

Metastasis is driven by sequential elevation of H-ras and Smad2 levels.

Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia

Mouse strain-dependent heterogeneity of resting limbal vasculature

Multiple self-healing squamous epithelioma (MSSE): rare variants in an adjacent region of chromosome 9q22.3 to known TGFBR1 mutations suggest a digenic or multilocus etiology

Mutations of TGFbeta signaling molecules in human disease

Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term TβRI/II kinase inhibition with LY2109761.

RNA and protein localisations of TGFβ2 in the early mouse embryo suggest an involvement in cardiac development ⬇️

ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation

Smad3-mediated recruitment of the methyltransferase SETDB1/ESET controls Snail1 expression and epithelial-mesenchymal transition.

TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis ⬇️

TGF beta inhibition for cancer therapy

TGF beta signaling in health and disease

TGF-beta antagonists: why suppress a tumor suppressor?

TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion

TGFbeta inhibition of yolk-sac-like differentiation of human embryonic stem-cell-derived embryoid bodies illustrates differences between early mouse and human development

TGFβ biology in cancer progression and immunotherapy

TGFβ1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo.

Taking thalidomide out of rehab

Targeting TGF-β Signaling for Therapeutic Gain

Targeting the TGFβ signalling pathway in disease

The Role of TGF? in Mouse Development ⬇️

The complexities of TGF-β action during mammary and squamous cell carcinogenesis

The paradoxical TGF-β vasculopathies ⬇️

The type I TGF-beta receptor is covalently modified and regulated by sumoylation

Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion ⬇️

Transforming growth factor-beta in breast cancer: too much, too late

Transforming growth factor-beta receptor inhibition enhances adenoviral infectability of carcinoma cells via up-regulation of Coxsackie and Adenovirus Receptor in conjunction with reversal of epithelial-mesenchymal transition.

Transforming growth factor-beta1 mediates cellular response to DNA damage in situ.

α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas