Lista de obras -

1010 - CHARACTERIZING HOXA-EXPRESSING ENDOTHELIAL AND HAEMATOPOIETIC POPULATIONS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS

scholarly article

3176 – MULTIPOTENT RAG1+ PROGENITORS EMERGE DIRECTLY FROM HEMOGENIC ENDOTHELIUM IN HUMAN PSC DERIVED HEMOPOIETIC ORGANOIDS ⬇️

artículo científico publicado en 2019

A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells

artículo científico publicado en 2016

A method for genetic modification of human embryonic stem cells using electroporation

artículo científico publicado en 2007

A mouse carrying the green fluorescent protein gene targeted to the Pdx1 locus facilitates the study of pancreas development and function.

artículo científico publicado en 2006

A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies

artículo científico publicado en 2008

A protocol for removal of antibiotic resistance cassettes from human embryonic stem cells genetically modified by homologous recombination or transgenesis

scientific article published on 01 January 2008

A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives.

artículo científico publicado en 2011

ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy.

artículo científico publicado en 2016

APELIN promotes hematopoiesis from human embryonic stem cells

scientific article published on 18 May 2012

An INSULIN-GFP/GLUCAGON-mCherry reporter line for the study of human pancreatic endocrine cell development

artículo científico

Analysis of mitochondrial function and localisation during human embryonic stem cell differentiation in vitro.

artículo científico publicado en 2012

Blood cells form from phenotypically distinct precursors during human blast colony differentiation

artículo científico publicado en 2015

Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity

artículo científico publicado en 2011

Building better beta cells

scientific article published on 01 April 2008

CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells

artículo científico publicado en 2016

CD90 Marks a Mesenchymal Program in Human Thymic Epithelial Cells <i>In Vitro</i> and <i>In Vivo</i>

artículo científico publicado en 2022

CRISPR/Cas9 gene editing of a SOX9 reporter human iPSC line to produce two TRPV4 patient heterozygous missense mutant iPSC lines, MCRIi001-A-3 (TRPV4 p.F273L) and MCRIi001-A-4 (TRPV4 p.P799L)

scientific article published on 03 August 2020

Coculturing with endothelial cells promotes in vitro maturation and electrical coupling of human embryonic stem cell-derived cardiomyocytes

artículo científico publicado en 2017

Defined substrates for pluripotent stem cells: are we there yet? ⬇️

artículo científico publicado el 1 de diciembre de 2010

Derivation of endothelial cells from human embryonic stem cells in fully defined medium enables identification of lysophosphatidic acid and platelet activating factor as regulators of eNOS localization

artículo científico publicado en 2012

Derivation of insulin-producing beta-cells from human pluripotent stem cells

artículo científico publicado en 2014

Differentiating embryonic stem cells pass through 'temporal windows' that mark responsiveness to exogenous and paracrine mesendoderm inducing signals

artículo científico publicado en 2010

Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis

artículo científico publicado en 2007

Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros.

artículo científico publicado en 2016

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

artículo científico publicado en 2013

Directed differentiation of human embryonic stem cells as spin embryoid bodies and a description of the hematopoietic blast colony forming assay

artículo científico publicado en 2008

Efficient Cre-mediated deletion in cardiac progenitor cells conferred by a 3'UTR-ires-Cre allele of the homeobox gene Nkx2-5.

artículo científico publicado en 2002

Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations.

artículo científico publicado en 2014

Efficient generation of NKX6-1+ pancreatic progenitors from multiple human pluripotent stem cell lines

artículo científico publicado en 2015

Efficient generation of adipocytes in a dish ⬇️

artículo científico publicado el 2 de febrero de 2012

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents.

artículo científico publicado en 2016

Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid

artículo científico publicado en 2007

Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.

scientific article published on 28 June 2016

Enforced expression of Mixl1 during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation

scientific journal article

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

artículo científico publicado en 2016

ErythRED, a hESC line enabling identification of erythroid cells

artículo científico publicado en 2009

Expansion of human embryonic stem cells in vitro

artículo científico publicado en 2008

Expression from a betageo gene trap in the Slain1 gene locus is predominantly associated with the developing nervous system.

artículo científico publicado en 2010

Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells

artículo científico publicado en 2020

FOXN1 (GFP/w) reporter hESCs enable identification of integrin-β4, HLA-DR, and EpCAM as markers of human PSC-derived FOXN1(+) thymic epithelial progenitors.

artículo científico publicado en 2014

Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation.

artículo científico publicado en 2005

Fourier transform infrared microspectroscopy identifies early lineage commitment in differentiating human embryonic stem cells

artículo científico publicado en 2009

Fourier transform infrared microspectroscopy reveals that tissue culture conditions affect the macromolecular phenotype of human embryonic stem cells

artículo científico publicado en 2013

Fourier transform infrared microspectroscopy reveals unique phenotypes for human embryonic and induced pluripotent stem cell lines and their progeny.

artículo científico publicado en 2013

Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.

artículo científico publicado en 2013

Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration

artículo científico publicado en 2017

GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives

artículo científico publicado en 2016

Generating GABAergic cerebral cortical interneurons from mouse and human embryonic stem cells.

artículo científico

Generation of RAB39B knockout isogenic human embryonic stem cell lines to model RAB39B-mediated Parkinson's disease.

artículo científico publicado en 2018

Generation of a SOX9-tdTomato reporter human iPSC line, MCRIi001-A-2, using CRISPR/Cas9 editing

artículo científico publicado en 2019

Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing

scientific article published on 23 April 2019

Generation of a heterozygous COL2A1 (p.R989C) spondyloepiphyseal dysplasia congenita mutation iPSC line, MCRIi001-B, using CRISPR/Cas9 gene editing

artículo científico publicado en 2020

Generation of human embryonic stem cell reporter knock-in lines by homologous recombination

artículo científico publicado en 2009

Generation of human female reproductive tract epithelium from human embryonic stem cells.

artículo científico publicado en 2011

Generation of iPSC lines from peripheral blood mononuclear cells from 5 healthy adults

scientific article published on 27 December 2018

Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.

artículo científico publicado en 2013

Generation of seven iPSC lines from peripheral blood mononuclear cells suitable to investigate Autism Spectrum Disorder

scientific article published on 01 August 2019

Hrk/DP5 contributes to the apoptosis of select neuronal populations but is dispensable for haematopoietic cell apoptosis.

scientific article published on 29 May 2007

Human chondrogenic paraxial mesoderm, directed specification and prospective isolation from pluripotent stem cells

artículo científico publicado en 2012

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages

artículo científico publicado en 2015

Human embryonic stem cell derived mesenchymal progenitors express cardiac markers but do not form contractile cardiomyocytes.

artículo científico publicado en 2013

Human haematopoietic stem cell development: from the embryo to the dish

artículo científico publicado en 2017

Human yolk sac-like haematopoiesis generates RUNX1- and GFI1/1B-dependent blood and SOX17-positive endothelium

artículo científico publicado en 2020

Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes

artículo científico publicado en 2019

Inhibition of DYRK1A disrupts neural lineage specification in human pluripotent stem cells

artículo científico publicado en 2017

Integrin αvβ5 heterodimer is a specific marker of human pancreatic beta cells

artículo científico publicado en 2021

Isolation of human lymphatic endothelial cells by multi-parameter fluorescence-activated cell sorting

artículo científico publicado en 2015

Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells

article

Long-Term Maintenance of Human Pluripotent Stem Cells on cRGDfK-Presenting Synthetic Surfaces.

artículo científico publicado en 2018

Magnetic Resonance Imaging of Iron Oxide-Labeled Human Embryonic Stem Cell-Derived Cardiac Progenitors

artículo científico publicado en 2015

Microbioreactor arrays for full factorial screening of exogenous and paracrine factors in human embryonic stem cell differentiation.

artículo científico publicado en 2012

Mimicry of embryonic circulation enhances the hoxa hemogenic niche and human blood development

scientific article published in 2022

Mixl1 and oct4 proteins are transiently co-expressed in differentiating mouse and human embryonic stem cells.

artículo científico publicado en 2005

Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo

scientific journal article

Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids

artículo científico publicado en 2020

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

artículo científico publicado en 2018

NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes.

artículo científico publicado en 2011

Overcoming Monocarboxylate Transporter 8 (MCT8)-Deficiency to Promote Human Oligodendrocyte Differentiation and Myelination

artículo científico publicado en 2017

Pancreas differentiation of mouse ES cells

artículo científico publicado en 2007

Pancreatic differentiation from pluripotent stem cells: tweaking the system.

artículo científico publicado en 2009

Pdgfrα and Flk1 are direct target genes of Mixl1 in differentiating embryonic stem cells.

artículo científico publicado en 2011

Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death

artículo científico publicado en 2004

Productive Infection of Human Embryonic Stem Cell-Derived NKX2.1+ Respiratory Progenitors with Human Rhinovirus.

artículo científico publicado en 2015

Publisher Correction: The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome

artículo científico publicado en 2019

RUNX1 AND GROUP F SOX GENES ARE REQUIRED AT DISTINCT STAGES FOR HUMAN HAEMATOPOIETIC DEVELOPMENT

scholarly article

Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin

artículo científico publicado en 2004

Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development

artículo científico publicado en 2017

Reshaping pluripotent stem cells

artículo científico publicado en 2009

Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells

artículo científico publicado en 2004

Rewiring immunity: generating a functional thymus from hESCs… are we there yet?

artículo científico publicado en 2013

SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells. ⬇️

artículo científico publicado en 2011

SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development.

artículo científico publicado en 2014

Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts

artículo científico publicado en 2015

Spatio-temporal re-organization of replication foci accompanies replication domain consolidation during human pluripotent stem cell lineage specification.

artículo científico publicado en 2016

Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells.

artículo científico publicado en 2011

Stems cells and the price of immortality

artículo científico publicado en 2008

Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors.

artículo científico publicado en 2007

Temporal restriction of pancreatic branching competence during embryogenesis is mirrored in differentiating embryonic stem cells

artículo científico publicado en 2011

The Mix family of homeobox genes--key regulators of mesendoderm formation during vertebrate development.

artículo científico publicado en 2012

The characterisation of pluripotent and multipotent stem cells using Fourier transform infrared microspectroscopy.

scientific article published on 26 August 2013

The hESC line Envy expresses high levels of GFP in all differentiated progeny.

artículo científico publicado en 2005

The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells

artículo científico publicado en 2005

The role of cardiac transcription factor NKX2-5 in regulating the human cardiac miRNAome

artículo científico publicado en 2019

The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line

scientific article published on 04 May 2019

Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene.

artículo científico publicado en 2006

WNT3A promotes hematopoietic or mesenchymal differentiation from hESCs depending on the time of exposure

artículo científico publicado en 2013

WNT9A Is a Conserved Regulator of Hematopoietic Stem and Progenitor Cell Development

artículo científico publicado en 2018

β-cell regeneration and differentiation: how close are we to the 'holy grail'?

artículo científico publicado en 2014

Lista de obras de

1010 - CHARACTERIZING HOXA-EXPRESSING ENDOTHELIAL AND HAEMATOPOIETIC POPULATIONS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS

3176 – MULTIPOTENT RAG1+ PROGENITORS EMERGE DIRECTLY FROM HEMOGENIC ENDOTHELIUM IN HUMAN PSC DERIVED HEMOPOIETIC ORGANOIDS ⬇️

A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells

A method for genetic modification of human embryonic stem cells using electroporation

A mouse carrying the green fluorescent protein gene targeted to the Pdx1 locus facilitates the study of pancreas development and function.

A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies

A protocol for removal of antibiotic resistance cassettes from human embryonic stem cells genetically modified by homologous recombination or transgenesis

A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives.

ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy.

APELIN promotes hematopoiesis from human embryonic stem cells

An INSULIN-GFP/GLUCAGON-mCherry reporter line for the study of human pancreatic endocrine cell development

Analysis of mitochondrial function and localisation during human embryonic stem cell differentiation in vitro.

Blood cells form from phenotypically distinct precursors during human blast colony differentiation

Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity

Building better beta cells

CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells

CD90 Marks a Mesenchymal Program in Human Thymic Epithelial Cells <i>In Vitro</i> and <i>In Vivo</i>

CRISPR/Cas9 gene editing of a SOX9 reporter human iPSC line to produce two TRPV4 patient heterozygous missense mutant iPSC lines, MCRIi001-A-3 (TRPV4 p.F273L) and MCRIi001-A-4 (TRPV4 p.P799L)

Coculturing with endothelial cells promotes in vitro maturation and electrical coupling of human embryonic stem cell-derived cardiomyocytes

Defined substrates for pluripotent stem cells: are we there yet? ⬇️

Derivation of endothelial cells from human embryonic stem cells in fully defined medium enables identification of lysophosphatidic acid and platelet activating factor as regulators of eNOS localization

Derivation of insulin-producing beta-cells from human pluripotent stem cells

Differentiating embryonic stem cells pass through 'temporal windows' that mark responsiveness to exogenous and paracrine mesendoderm inducing signals

Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis

Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros.

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

Directed differentiation of human embryonic stem cells as spin embryoid bodies and a description of the hematopoietic blast colony forming assay

Efficient Cre-mediated deletion in cardiac progenitor cells conferred by a 3'UTR-ires-Cre allele of the homeobox gene Nkx2-5.

Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations.

Efficient generation of NKX6-1+ pancreatic progenitors from multiple human pluripotent stem cell lines

Efficient generation of adipocytes in a dish ⬇️

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents.

Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid

Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.

Enforced expression of Mixl1 during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

ErythRED, a hESC line enabling identification of erythroid cells

Expansion of human embryonic stem cells in vitro

Expression from a betageo gene trap in the Slain1 gene locus is predominantly associated with the developing nervous system.

Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells

FOXN1 (GFP/w) reporter hESCs enable identification of integrin-β4, HLA-DR, and EpCAM as markers of human PSC-derived FOXN1(+) thymic epithelial progenitors.

Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation.

Fourier transform infrared microspectroscopy identifies early lineage commitment in differentiating human embryonic stem cells

Fourier transform infrared microspectroscopy reveals that tissue culture conditions affect the macromolecular phenotype of human embryonic stem cells

Fourier transform infrared microspectroscopy reveals unique phenotypes for human embryonic and induced pluripotent stem cell lines and their progeny.

Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.

Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration

GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives

Generating GABAergic cerebral cortical interneurons from mouse and human embryonic stem cells.

Generation of RAB39B knockout isogenic human embryonic stem cell lines to model RAB39B-mediated Parkinson's disease.

Generation of a SOX9-tdTomato reporter human iPSC line, MCRIi001-A-2, using CRISPR/Cas9 editing

Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing

Generation of a heterozygous COL2A1 (p.R989C) spondyloepiphyseal dysplasia congenita mutation iPSC line, MCRIi001-B, using CRISPR/Cas9 gene editing

Generation of human embryonic stem cell reporter knock-in lines by homologous recombination

Generation of human female reproductive tract epithelium from human embryonic stem cells.

Generation of iPSC lines from peripheral blood mononuclear cells from 5 healthy adults

Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.

Generation of seven iPSC lines from peripheral blood mononuclear cells suitable to investigate Autism Spectrum Disorder

Hrk/DP5 contributes to the apoptosis of select neuronal populations but is dispensable for haematopoietic cell apoptosis.

Human chondrogenic paraxial mesoderm, directed specification and prospective isolation from pluripotent stem cells

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages

Human embryonic stem cell derived mesenchymal progenitors express cardiac markers but do not form contractile cardiomyocytes.

Human haematopoietic stem cell development: from the embryo to the dish

Human yolk sac-like haematopoiesis generates RUNX1- and GFI1/1B-dependent blood and SOX17-positive endothelium

Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes

Inhibition of DYRK1A disrupts neural lineage specification in human pluripotent stem cells

Integrin αvβ5 heterodimer is a specific marker of human pancreatic beta cells

Isolation of human lymphatic endothelial cells by multi-parameter fluorescence-activated cell sorting

Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells

Long-Term Maintenance of Human Pluripotent Stem Cells on cRGDfK-Presenting Synthetic Surfaces.

Magnetic Resonance Imaging of Iron Oxide-Labeled Human Embryonic Stem Cell-Derived Cardiac Progenitors

Microbioreactor arrays for full factorial screening of exogenous and paracrine factors in human embryonic stem cell differentiation.

Mimicry of embryonic circulation enhances the hoxa hemogenic niche and human blood development

Mixl1 and oct4 proteins are transiently co-expressed in differentiating mouse and human embryonic stem cells.

Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo

Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes.

Overcoming Monocarboxylate Transporter 8 (MCT8)-Deficiency to Promote Human Oligodendrocyte Differentiation and Myelination