Lista de obras - David Palmer - Dominio Público Uruguay

A missense mutation (c.184C>T) in ovine CLN6 causes neuronal ceroid lipofuscinosis in Merino sheep whereas affected South Hampshire sheep have reduced levels of CLN6 mRNA.

artículo científico publicado en 2006

A new large animal model of CLN5 neuronal ceroid lipofuscinosis in Borderdale sheep is caused by a nucleotide substitution at a consensus splice site (c.571+1G>A) leading to excision of exon 3.

artículo científico publicado en 2007

A triad of highly divergent polymeric immunoglobulin receptor (PIGR) haplotypes with major effect on IgA concentration in bovine milk

artículo científico publicado en 2013

Accumulation of sphingolipid activator proteins (SAPs) A and D in granular osmiophilic deposits in miniature Schnauzer dogs with ceroid-lipofuscinosis

artículo científico publicado en 1997

Activation of non-neuronal cells within the prenatal developing brain of sheep with neuronal ceroid lipofuscinosis

artículo científico publicado en 2006

An EEG Investigation of Sleep Homeostasis in Healthy and CLN5 Batten Disease Affected Sheep.

artículo científico publicado en 2016

Batten disease and the ATP synthase subunit c turnover pathway: raising antibodies to subunit c.

artículo científico publicado en 1995

Biochemical studies on ovine ceroid-lipofuscinosis

1987 doctoral thesis by David Norris Palmer at Massey University

Ceroid lipofuscinosis in sheep. I. Bis(monoacylglycero)phosphate, dolichol, ubiquinone, phospholipids, fatty acids, and fluorescence in liver lipopigment lipids

artículo científico publicado en 1986

Ceroid lipofuscinosis in sheep. II. The major component of the lipopigment in liver, kidney, pancreas, and brain is low molecular weight protein.

artículo científico publicado en 1986

Ceroid-lipofuscinosis (Batten's disease): pathogenesis and sequential neuropathological changes in the ovine model

artículo científico publicado en 1989

Ceroid-lipofuscinosis in miniature Schnauzer dogs

artículo científico publicado en 1997

Changes in GABAergic neuron distribution in situ and in neuron cultures in ovine (OCL6) Batten disease

artículo científico publicado en 2001

Chronic oral administration of minocycline to sheep with ovine CLN6 neuronal ceroid lipofuscinosis maintains pharmacological concentrations in the brain but does not suppress neuroinflammation or disease progression ⬇️

artículo científico publicado el 30 de julio de 2013

Computed tomography provides enhanced techniques for longitudinal monitoring of progressive intracranial volume loss associated with regional neurodegeneration in ovine neuronal ceroid lipofuscinoses

artículo científico publicado en 2018

Defective endoplasmic reticulum-resident membrane protein CLN6 affects lysosomal degradation of endocytosed arylsulfatase A

artículo científico publicado en 2004

Different patterns of hydrophobic protein storage in different forms of neuronal ceroid lipofuscinosis (NCL, Batten disease)

artículo científico publicado en 1997

Disease-specific pathology in neurons cultured from sheep affected with ceroid lipofuscinosis

artículo científico publicado en 1999

Enhanced expression of manganese-dependent superoxide dismutase in human and sheep CLN6 tissues

artículo científico publicado en 2003

Glial activation spreads from specific cerebral foci and precedes neurodegeneration in presymptomatic ovine neuronal ceroid lipofuscinosis (CLN6).

artículo científico publicado en 2005

Immunocytochemical studies in the ceroid-lipofuscinoses (Batten disease) using antibodies to subunit c of mitochondrial ATP synthase

scientific article published on 01 June 1995

In vitro culture of neurons from sheep with Batten disease

artículo científico publicado en 1999

Inhibition of storage pathology in prenatal CLN5-deficient sheep neural cultures by lentiviral gene therapy.

artículo científico publicado en 2013

Ion pores made of mitochondrial ATP synthase subunit c in the neuronal plasma membrane and Batten disease

artículo científico publicado en 1999

Lentiviral-mediated gene transfer to the sheep brain: implications for gene therapy in Batten disease.

artículo científico publicado en 2011

Location and connectivity determine GABAergic interneuron survival in the brains of South Hampshire sheep with CLN6 neuronal ceroid lipofuscinosis

artículo científico publicado en 2008

Longitudinal In Vivo Monitoring of the CNS Demonstrates the Efficacy of Gene Therapy in a Sheep Model of CLN5 Batten Disease

article

Lysine 43 is trimethylated in subunit C from bovine mitochondrial ATP synthase and in storage bodies associated with batten disease

artículo científico publicado en 2004

Mapping quantitative trait loci (QTL) in sheep. I. A new male framework linkage map and QTL for growth rate and body weight

artículo científico publicado en 2009

Metabolomic investigation of CLN6 neuronal ceroid lipofuscinosis in affected South Hampshire sheep

artículo científico publicado en 2007

Mitochondrial ATP synthase subunit c storage in the ceroid-lipofuscinoses (Batten disease)

scientific article published on 01 February 1992

Molecular neuropathology of the synapse in sheep with CLN5 Batten disease

artículo científico publicado en 2015

NCL disease mechanisms

artículo científico

Neuronal ceroid lipofuscinosis in Devon cattle is caused by a single base duplication (c.662dupG) in the bovine CLN5 gene

artículo científico publicado en 2006

Neuronal ceroid lipofuscinosis in Merino sheep

artículo científico publicado en 2002

Neuronal ceroid-lipofuscinosis in Borderdale sheep

artículo científico publicado en 2002

Neuropeptide changes and neuroactive amino acids in CSF from humans and sheep with neuronal ceroid lipofuscinoses (NCLs, Batten disease).

artículo científico publicado en 2009

Ovine ceroid lipofuscinosis. The major lipopigment protein and the lipid-binding subunit of mitochondrial ATP synthase have the same NH2-terminal sequence

scientific article published on 01 April 1989

Ovine ceroid-lipofuscinosis II: Pathologic changes interpreted in light of biochemical observations

artículo científico publicado en 1988

Ovine ceroid-lipofuscinosis. I: Lipopigment composition is indicative of a lysosomal proteinosis.

artículo científico publicado en 1988

Practical implications of motion correction with motion insensitive radial k-space acquisitions in MRI.

artículo científico publicado en 2018

Rapid and Progressive Regional Brain Atrophy in CLN6 Batten Disease Affected Sheep Measured with Longitudinal Magnetic Resonance Imaging

artículo científico publicado en 2015

Rapid, quantitative analysis of 3'- and 6'-sialyllactose in milk by flow-injection analysis-mass spectrometry: screening of milks for naturally elevated sialyllactose concentration

artículo científico publicado en 2013

Recent studies of ovine neuronal ceroid lipofuscinoses from BARN, the Batten Animal Research Network

artículo científico publicado en 2015

Sheep and other animals with ceroid-lipofuscinoses: their relevance to Batten disease.

artículo científico publicado en 1992

Splicing variants in sheep CLN3, the gene underlying juvenile neuronal ceroid lipofuscinosis

artículo científico publicado en 1999

The development and characterisation of complex ovine neuron cultures from fresh and frozen foetal neurons

artículo científico publicado en 2006

The development of brain magnetic resonance approaches in large animal models for preclinical research

artículo científico publicado en 2019

The neuronal ceroid-lipofuscinoses (Batten disease): comparative aspects

artículo científico publicado en 1995

The origin of fluorescence in the neuronal ceroid lipofuscinoses (Batten disease) and neuron cultures from affected sheep for studies of neurodegeneration

artículo científico publicado en 2002

The specific loss of GnRH-positive neurons from the hypothalamus of sheep with CLN6 neuronal ceroid lipofuscinosis occurs without glial activation and has only minor effects on reproduction ⬇️

artículo científico publicado el 24 de noviembre de 2010

Translational neurophysiology in sheep: measuring sleep and neurological dysfunction in CLN5 Batten disease affected sheep.

artículo científico publicado en 2015

Variant proteins in ovine ceroid-lipofuscinosis

scientific article published on 01 June 1995

Lista de obras de David Palmer

A missense mutation (c.184C>T) in ovine CLN6 causes neuronal ceroid lipofuscinosis in Merino sheep whereas affected South Hampshire sheep have reduced levels of CLN6 mRNA.

A new large animal model of CLN5 neuronal ceroid lipofuscinosis in Borderdale sheep is caused by a nucleotide substitution at a consensus splice site (c.571+1G>A) leading to excision of exon 3.

A triad of highly divergent polymeric immunoglobulin receptor (PIGR) haplotypes with major effect on IgA concentration in bovine milk

Accumulation of sphingolipid activator proteins (SAPs) A and D in granular osmiophilic deposits in miniature Schnauzer dogs with ceroid-lipofuscinosis

Activation of non-neuronal cells within the prenatal developing brain of sheep with neuronal ceroid lipofuscinosis

An EEG Investigation of Sleep Homeostasis in Healthy and CLN5 Batten Disease Affected Sheep.

Batten disease and the ATP synthase subunit c turnover pathway: raising antibodies to subunit c.

Biochemical studies on ovine ceroid-lipofuscinosis

Ceroid lipofuscinosis in sheep. I. Bis(monoacylglycero)phosphate, dolichol, ubiquinone, phospholipids, fatty acids, and fluorescence in liver lipopigment lipids

Ceroid lipofuscinosis in sheep. II. The major component of the lipopigment in liver, kidney, pancreas, and brain is low molecular weight protein.

Ceroid-lipofuscinosis (Batten's disease): pathogenesis and sequential neuropathological changes in the ovine model

Ceroid-lipofuscinosis in miniature Schnauzer dogs

Changes in GABAergic neuron distribution in situ and in neuron cultures in ovine (OCL6) Batten disease

Chronic oral administration of minocycline to sheep with ovine CLN6 neuronal ceroid lipofuscinosis maintains pharmacological concentrations in the brain but does not suppress neuroinflammation or disease progression ⬇️

Computed tomography provides enhanced techniques for longitudinal monitoring of progressive intracranial volume loss associated with regional neurodegeneration in ovine neuronal ceroid lipofuscinoses

Defective endoplasmic reticulum-resident membrane protein CLN6 affects lysosomal degradation of endocytosed arylsulfatase A

Different patterns of hydrophobic protein storage in different forms of neuronal ceroid lipofuscinosis (NCL, Batten disease)

Disease-specific pathology in neurons cultured from sheep affected with ceroid lipofuscinosis

Enhanced expression of manganese-dependent superoxide dismutase in human and sheep CLN6 tissues

Glial activation spreads from specific cerebral foci and precedes neurodegeneration in presymptomatic ovine neuronal ceroid lipofuscinosis (CLN6).

Immunocytochemical studies in the ceroid-lipofuscinoses (Batten disease) using antibodies to subunit c of mitochondrial ATP synthase

In vitro culture of neurons from sheep with Batten disease

Inhibition of storage pathology in prenatal CLN5-deficient sheep neural cultures by lentiviral gene therapy.

Ion pores made of mitochondrial ATP synthase subunit c in the neuronal plasma membrane and Batten disease

Lentiviral-mediated gene transfer to the sheep brain: implications for gene therapy in Batten disease.

Location and connectivity determine GABAergic interneuron survival in the brains of South Hampshire sheep with CLN6 neuronal ceroid lipofuscinosis

Longitudinal In Vivo Monitoring of the CNS Demonstrates the Efficacy of Gene Therapy in a Sheep Model of CLN5 Batten Disease

Lysine 43 is trimethylated in subunit C from bovine mitochondrial ATP synthase and in storage bodies associated with batten disease

Mapping quantitative trait loci (QTL) in sheep. I. A new male framework linkage map and QTL for growth rate and body weight

Metabolomic investigation of CLN6 neuronal ceroid lipofuscinosis in affected South Hampshire sheep

Mitochondrial ATP synthase subunit c storage in the ceroid-lipofuscinoses (Batten disease)

Molecular neuropathology of the synapse in sheep with CLN5 Batten disease

NCL disease mechanisms

Neuronal ceroid lipofuscinosis in Devon cattle is caused by a single base duplication (c.662dupG) in the bovine CLN5 gene

Neuronal ceroid lipofuscinosis in Merino sheep

Neuronal ceroid-lipofuscinosis in Borderdale sheep

Neuropeptide changes and neuroactive amino acids in CSF from humans and sheep with neuronal ceroid lipofuscinoses (NCLs, Batten disease).

Ovine ceroid lipofuscinosis. The major lipopigment protein and the lipid-binding subunit of mitochondrial ATP synthase have the same NH2-terminal sequence

Ovine ceroid-lipofuscinosis II: Pathologic changes interpreted in light of biochemical observations

Ovine ceroid-lipofuscinosis. I: Lipopigment composition is indicative of a lysosomal proteinosis.

Practical implications of motion correction with motion insensitive radial k-space acquisitions in MRI.

Rapid and Progressive Regional Brain Atrophy in CLN6 Batten Disease Affected Sheep Measured with Longitudinal Magnetic Resonance Imaging

Rapid, quantitative analysis of 3'- and 6'-sialyllactose in milk by flow-injection analysis-mass spectrometry: screening of milks for naturally elevated sialyllactose concentration

Recent studies of ovine neuronal ceroid lipofuscinoses from BARN, the Batten Animal Research Network

Sheep and other animals with ceroid-lipofuscinoses: their relevance to Batten disease.

Splicing variants in sheep CLN3, the gene underlying juvenile neuronal ceroid lipofuscinosis

The development and characterisation of complex ovine neuron cultures from fresh and frozen foetal neurons

The development of brain magnetic resonance approaches in large animal models for preclinical research

The neuronal ceroid-lipofuscinoses (Batten disease): comparative aspects

The origin of fluorescence in the neuronal ceroid lipofuscinoses (Batten disease) and neuron cultures from affected sheep for studies of neurodegeneration

The specific loss of GnRH-positive neurons from the hypothalamus of sheep with CLN6 neuronal ceroid lipofuscinosis occurs without glial activation and has only minor effects on reproduction ⬇️

Translational neurophysiology in sheep: measuring sleep and neurological dysfunction in CLN5 Batten disease affected sheep.

Variant proteins in ovine ceroid-lipofuscinosis