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Antigen- and Epitope-Delivering Nanoparticles Targeting Liver Induce Comparable Immunotolerance in Allergic Airway Disease and Anaphylaxis as Nanoparticle-Delivering Pharmaceuticals

artículo científico publicado en 2020

Aspect ratio determines the quantity of mesoporous silica nanoparticle uptake by a small GTPase-dependent macropinocytosis mechanism.

artículo científico publicado en 2011

Aspect ratio plays a role in the hazard potential of CeO2 nanoparticles in mouse lung and zebrafish gastrointestinal tract

artículo científico publicado en 2014

Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo

artículo científico publicado en 2013

Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals

artículo científico publicado en 2015

Decreased dissolution of ZnO by iron doping yields nanoparticles with reduced toxicity in the rodent lung and zebrafish embryos

artículo científico publicado en 2011

Designed synthesis of CeO2 nanorods and nanowires for studying toxicological effects of high aspect ratio nanomaterials

artículo científico publicado en 2012

Differences in the Toxicological Potential of 2D versus Aggregated Molybdenum Disulfide in the Lung

artículo científico publicado en 2015

Differential expression of syndecan-1 mediates cationic nanoparticle toxicity in undifferentiated versus differentiated normal human bronchial epithelial cells

artículo científico publicado en 2011

Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during aerosolized inhalation in mice

artículo científico publicado en 2016

Dispersal state of multiwalled carbon nanotubes elicits profibrogenic cellular responses that correlate with fibrogenesis biomarkers and fibrosis in the murine lung

artículo científico publicado en 2011

Dispersion and stability optimization of TiO2 nanoparticles in cell culture media.

scientific article published on October 2010

Engineering an effective immune adjuvant by designed control of shape and crystallinity of aluminum oxyhydroxide nanoparticles

artículo científico publicado en 2013

Enhanced Immune Adjuvant Activity of Aluminum Oxyhydroxide Nanorods through Cationic Surface Functionalization.

artículo científico publicado en 2017

Enhancing the imaging and biosafety of upconversion nanoparticles through phosphonate coating.

artículo científico publicado en 2015

Facilitating Translational Nanomedicine via Predictive Safety Assessment

artículo científico publicado en 2017

High content screening in zebrafish speeds up hazard ranking of transition metal oxide nanoparticles

artículo científico publicado en 2011

Implications of the Differential Toxicological Effects of III-V Ionic and Particulate Materials for Hazard Assessment of Semiconductor Slurries

artículo científico publicado en 2015

Interference in autophagosome fusion by rare earth nanoparticles disrupts autophagic flux and regulation of an interleukin-1β producing inflammasome.

artículo científico publicado en 2014

Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium

artículo científico publicado en 2013

Mammalian Cells Exhibit a Range of Sensitivities to Silver Nanoparticles that are Partially Explicable by Variations in Antioxidant Defense and Metallothionein Expression

artículo científico publicado en 2015

Mechanistic Differences in Cell Death Responses to Metal-Based Engineered Nanomaterials in Kupffer Cells and Hepatocytes

scientific article published on 26 April 2020

NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes

artículo científico publicado en 2015

NLRP3 inflammasome activation induced by engineered nanomaterials

artículo científico publicado en 2013

Nanomaterial toxicity testing in the 21st century: use of a predictive toxicological approach and high-throughput screening

artículo científico publicado en 2013

Nanosilver incurs an adaptive shunt of energy metabolism mode to glycolysis in tumor and nontumor cells

artículo científico publicado en 2014

PdO doping tunes band-gap energy levels as well as oxidative stress responses to a Co₃O₄ p-type semiconductor in cells and the lung

artículo científico publicado en 2014

Pluronic F108 coating decreases the lung fibrosis potential of multiwall carbon nanotubes by reducing lysosomal injury

artículo científico publicado en 2012

Predictive Metabolomic Signatures for Safety Assessment of Metal Oxide Nanoparticles

artículo científico publicado en 2019

Pro-Inflammatory and Pro-Fibrogenic Effects of Ionic and Particulate Arsenide and Indium-Containing Semiconductor Materials in the Murine Lung.

artículo científico publicado en 2017

Processing pathway dependence of amorphous silica nanoparticle toxicity: colloidal vs pyrolytic

artículo científico publicado en 2012

Quantitative techniques for assessing and controlling the dispersion and biological effects of multiwalled carbon nanotubes in mammalian tissue culture cells

artículo científico publicado en 2010

Reduction of Acute Inflammatory Effects of Fumed Silica Nanoparticles in the Lung by Adjusting Silanol Display through Calcination and Metal Doping

artículo científico publicado en 2015

Reduction of pulmonary toxicity of metal oxide nanoparticles by phosphonate-based surface passivation.

artículo científico publicado en 2017

Repetitive Dosing of Fumed Silica Leads to Profibrogenic Effects through Unique Structure-Activity Relationships and Biopersistence in the Lung

artículo científico publicado en 2016

Semiconductor Electronic Label-Free Assay for Predictive Toxicology

artículo científico publicado en 2016

Surface charge and cellular processing of covalently functionalized multiwall carbon nanotubes determine pulmonary toxicity

artículo científico publicado en 2013

Surface defects on plate-shaped silver nanoparticles contribute to its hazard potential in a fish gill cell line and zebrafish embryos

artículo científico publicado en 2012

Surface interactions with compartmentalized cellular phosphates explain rare earth oxide nanoparticle hazard and provide opportunities for safer design

artículo científico publicado en 2014

The Crystallinity and Aspect Ratio of Cellulose Nanomaterials Determine Their Pro-Inflammatory and Immune Adjuvant Effects In Vitro and In Vivo

scientific article published on 28 August 2019

The Genetic Heterogeneity among Different Mouse Strains Impacts the Lung Injury Potential of Multiwalled Carbon Nanotubes

artículo científico publicado en 2017

Toxicological Profiling of Highly Purified Metallic and Semiconducting Single-Walled Carbon Nanotubes in the Rodent Lung and E. coli

artículo científico publicado en 2016

Use of Polymeric Nanoparticle Platform Targeting the Liver To Induce Treg-Mediated Antigen-Specific Immune Tolerance in a Pulmonary Allergen Sensitization Model

scientific article published on 12 April 2019

Use of a high-throughput screening approach coupled with in vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials

artículo científico publicado en 2011

Use of a pro-fibrogenic mechanism-based predictive toxicological approach for tiered testing and decision analysis of carbonaceous nanomaterials

artículo científico publicado en 2015

Use of coated silver nanoparticles to understand the relationship of particle dissolution and bioavailability to cell and lung toxicological potential

artículo científico publicado en 2014

Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation

artículo científico publicado en 2012

Zebrafish high-throughput screening to study the impact of dissolvable metal oxide nanoparticles on the hatching enzyme, ZHE1

artículo científico publicado en 2013